EA201990298A1 - Способы и композиции для лечения рака - Google Patents
Способы и композиции для лечения ракаInfo
- Publication number
- EA201990298A1 EA201990298A1 EA201990298A EA201990298A EA201990298A1 EA 201990298 A1 EA201990298 A1 EA 201990298A1 EA 201990298 A EA201990298 A EA 201990298A EA 201990298 A EA201990298 A EA 201990298A EA 201990298 A1 EA201990298 A1 EA 201990298A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compositions
- methods
- cancer treatment
- seq
- polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6445—Haemoglobin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение относится к полипептиду, включающему или состоящему из полипептида с SEQ ID NO: 1, где остаток X в положении 89 в SEQ ID NO: 1 не является цистеином, или функционально эквивалентного варианта указанного полипептида, где остаток X в положении 89 в SEQ ID NO: 1 не является цистеином, и их применению в медицине, в частности, для профилактики и/или лечения рака.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16382339.6A EP3269734A1 (en) | 2016-07-15 | 2016-07-15 | Methods and compositions for the treatment of cancer |
PCT/EP2017/067998 WO2018011433A1 (en) | 2016-07-15 | 2017-07-17 | Methods and compositions for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201990298A1 true EA201990298A1 (ru) | 2019-06-28 |
Family
ID=56497695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201990298A EA201990298A1 (ru) | 2016-07-15 | 2017-07-17 | Способы и композиции для лечения рака |
Country Status (15)
Country | Link |
---|---|
US (1) | US11427621B2 (ru) |
EP (2) | EP3269734A1 (ru) |
JP (1) | JP7090593B2 (ru) |
KR (1) | KR102232500B1 (ru) |
CN (1) | CN109563151B (ru) |
AU (1) | AU2017295071B2 (ru) |
BR (1) | BR112019000732A2 (ru) |
CA (1) | CA3029781A1 (ru) |
EA (1) | EA201990298A1 (ru) |
IL (1) | IL264176B2 (ru) |
MA (1) | MA45675A (ru) |
MX (1) | MX2019000346A (ru) |
SG (1) | SG11201900021PA (ru) |
WO (1) | WO2018011433A1 (ru) |
ZA (1) | ZA201900960B (ru) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101729826B1 (ko) * | 2015-01-09 | 2017-05-11 | 주식회사 동희산업 | 플라스틱 연료탱크의 제조방법 |
KR101862239B1 (ko) * | 2016-07-07 | 2018-05-30 | 주식회사 동희산업 | 플라스틱 연료탱크의 제조방법 |
KR101859583B1 (ko) * | 2016-07-07 | 2018-06-27 | 주식회사 동희산업 | 플라스틱 연료탱크의 제조방법 |
EP3269734A1 (en) | 2016-07-15 | 2018-01-17 | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron | Methods and compositions for the treatment of cancer |
US20210238240A1 (en) * | 2018-08-20 | 2021-08-05 | Helix Nanotechnologies, Inc. | Methods and compositions for rna expression of myc inhibitors |
MX2021011320A (es) * | 2019-03-19 | 2021-12-10 | Fundacio Privada Inst Dinvestigacio Oncològica De Vall Hebron | Terapia de combinacion con omomyc y un anticuerpo que se une a pd-1 o a ctla-4 para el tratamiento del cancer. |
TWI829893B (zh) * | 2019-03-19 | 2024-01-21 | 瓦爾希伯倫私人腫瘤研究基金會 | 診斷肺癌的方法 |
KR102398339B1 (ko) * | 2020-01-09 | 2022-05-13 | 이화여자대학교 산학협력단 | 일산화질소 전달용 융합 펩타이드 및 이의 용도 |
WO2021208787A1 (zh) * | 2020-04-15 | 2021-10-21 | 徐荣臻 | 用于筛选药物的靶标多肽和筛选方法 |
EP4361633A1 (en) | 2022-10-25 | 2024-05-01 | Peptomyc, S.L. | Method for predicting response to a cancer treatment |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
DE3169595D1 (en) | 1980-11-10 | 1985-05-02 | Gersonde Klaus | Method of preparing lipid vesicles by ultrasonic treatment, the use of this method and apparatus for its application |
EP0088046B1 (de) | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
EP0143949B1 (en) | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmaceutical composition containing urokinase |
EP0654077A4 (en) | 1992-07-17 | 1996-03-13 | Ribozyme Pharm Inc | PROCESS AND REAGENT FOR THE TREATMENT OF DISEASES IN ANIMALS. |
US6447796B1 (en) | 1994-05-16 | 2002-09-10 | The United States Of America As Represented By The Secretary Of The Army | Sustained release hydrophobic bioactive PLGA microspheres |
CA2228374A1 (en) * | 1995-07-31 | 1997-02-13 | Charles R. Vinson | Extension of a protein-protein interaction surface to inactivate the function of a cellular protein |
US6395713B1 (en) | 1997-07-23 | 2002-05-28 | Ribozyme Pharmaceuticals, Inc. | Compositions for the delivery of negatively charged molecules |
EP1044021B1 (en) | 1998-01-05 | 2009-09-23 | The University of Washington | Enhanced transport using membrane disruptive agents |
DE60040274D1 (de) | 1999-03-10 | 2008-10-30 | Phogen Ltd | Verabreichung von nukleinsäuren und proteinen an zellen |
US20020130430A1 (en) | 2000-12-29 | 2002-09-19 | Castor Trevor Percival | Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products |
WO2002087541A1 (en) | 2001-04-30 | 2002-11-07 | Protiva Biotherapeutics Inc. | Lipid-based formulations for gene transfer |
US7060498B1 (en) | 2001-11-28 | 2006-06-13 | Genta Salus Llc | Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers |
US7141540B2 (en) | 2001-11-30 | 2006-11-28 | Genta Salus Llc | Cyclodextrin grafted biocompatible amphilphilic polymer and methods of preparation and use thereof |
WO2006135436A2 (en) | 2004-10-22 | 2006-12-21 | University Of Florida Research Foundation, Inc. | Inhibition of gene expression and therapeutic uses thereof |
WO2013063560A2 (en) | 2011-10-27 | 2013-05-02 | New York University | INHIBITION OF c-MYC UBIQUITINATION TO PREVENT CANCER INITIATION AND PROGRESSION |
EP2801370A1 (en) * | 2013-05-07 | 2014-11-12 | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron | Methods and compositions for the treatment of cancer |
EP3269734A1 (en) | 2016-07-15 | 2018-01-17 | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron | Methods and compositions for the treatment of cancer |
-
2016
- 2016-07-15 EP EP16382339.6A patent/EP3269734A1/en not_active Withdrawn
-
2017
- 2017-07-17 US US16/317,850 patent/US11427621B2/en active Active
- 2017-07-17 KR KR1020197004495A patent/KR102232500B1/ko active IP Right Grant
- 2017-07-17 EA EA201990298A patent/EA201990298A1/ru unknown
- 2017-07-17 CN CN201780043683.0A patent/CN109563151B/zh active Active
- 2017-07-17 MX MX2019000346A patent/MX2019000346A/es unknown
- 2017-07-17 BR BR112019000732A patent/BR112019000732A2/pt unknown
- 2017-07-17 WO PCT/EP2017/067998 patent/WO2018011433A1/en active Application Filing
- 2017-07-17 MA MA045675A patent/MA45675A/fr unknown
- 2017-07-17 EP EP17746413.8A patent/EP3484913B1/en active Active
- 2017-07-17 AU AU2017295071A patent/AU2017295071B2/en active Active
- 2017-07-17 SG SG11201900021PA patent/SG11201900021PA/en unknown
- 2017-07-17 JP JP2019501644A patent/JP7090593B2/ja active Active
- 2017-07-17 CA CA3029781A patent/CA3029781A1/en active Pending
-
2019
- 2019-01-09 IL IL264176A patent/IL264176B2/en unknown
- 2019-02-14 ZA ZA2019/00960A patent/ZA201900960B/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL264176A (en) | 2019-02-28 |
JP7090593B2 (ja) | 2022-06-24 |
KR20190032427A (ko) | 2019-03-27 |
KR102232500B1 (ko) | 2021-03-26 |
EP3484913B1 (en) | 2024-07-03 |
ZA201900960B (en) | 2020-05-27 |
WO2018011433A1 (en) | 2018-01-18 |
MA45675A (fr) | 2021-04-21 |
IL264176B1 (en) | 2023-03-01 |
EP3484913A1 (en) | 2019-05-22 |
BR112019000732A2 (pt) | 2019-07-30 |
CN109563151B (zh) | 2023-03-07 |
EP3269734A1 (en) | 2018-01-17 |
JP2019525753A (ja) | 2019-09-12 |
IL264176B2 (en) | 2023-07-01 |
CN109563151A (zh) | 2019-04-02 |
AU2017295071B2 (en) | 2022-06-09 |
CA3029781A1 (en) | 2018-01-18 |
SG11201900021PA (en) | 2019-01-30 |
MX2019000346A (es) | 2019-04-01 |
US20200247857A1 (en) | 2020-08-06 |
US11427621B2 (en) | 2022-08-30 |
AU2017295071A1 (en) | 2019-01-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA201990298A1 (ru) | Способы и композиции для лечения рака | |
SV2018005614A (es) | Inhibidores peptidicos del receptor de interleucina 23 y uso para tratar enfermedades inflamatorias | |
PH12015501983A1 (en) | Peptides and compositions for treatment of joint damage | |
SG10201907164SA (en) | Rna containing composition for treatment of tumor diseases | |
EA201791775A1 (ru) | Цистеиновая протеаза | |
NZ726448A (en) | Improved immunoglobulin variable domains | |
MD4733B1 (ru) | Антитела анти-TIGIT | |
MX2017005134A (es) | Tratamiento del cáncer con inmunoestimuladores. | |
PH12021550122A1 (en) | Solubilized apyrases, methods and use | |
TW201613977A (en) | Angiopoetin-like 4 (ANGPTL4) antibodies and methods of use | |
SG10201805646WA (en) | Angiopoietin-like 4 antibodies and methods of use | |
MY194448A (en) | Short synthetic peptide for treating diseases and/or conditions related to angiogenesis | |
SG10201809099PA (en) | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage | |
EA201691792A1 (ru) | Фармацевтические составы на основе вилдаглиптина | |
MX2015002279A (es) | Peptido pntx(19) sintético, composición farmacéutica.y uso. | |
BR112022001199A2 (pt) | Imunoterapia para poliomavírus | |
BR112019004102A2 (pt) | imunoterapia para poliomavírus | |
BR112018001207A2 (pt) | novo peptídeo e uso do mesmo | |
MA40642A (fr) | Nouveaux dérivés peptidiques et leurs utilisations | |
NZ734845A (en) | Use of short synthetic peptide for the treatment and/or prophylaxis of dry eye disease | |
MX2017007740A (es) | Peptido c-terminal de acetilcolinesterasa ciclico en el tratamiento o la prevencion de cancer o metastasis. | |
MX365952B (es) | Composiciones para la prevención y/o el tratamiento de patologías relacionadas con alfa-glucosidasa. | |
EA201692056A1 (ru) | Композиция для личной гигиены | |
MX2019004179A (es) | Composiciones de apilimod y metodos para utilizar las mismas en el tratamiento de la enfermedad de alzheimer. | |
MX2019001320A (es) | Composicion y uso de un peptido. |