SG10201809099PA - Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage - Google Patents

Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

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Publication number
SG10201809099PA
SG10201809099PA SG10201809099PA SG10201809099PA SG10201809099PA SG 10201809099P A SG10201809099P A SG 10201809099PA SG 10201809099P A SG10201809099P A SG 10201809099PA SG 10201809099P A SG10201809099P A SG 10201809099PA SG 10201809099P A SG10201809099P A SG 10201809099PA
Authority
SG
Singapore
Prior art keywords
tissue
peptide analogs
preventing
disorders associated
treating diseases
Prior art date
Application number
SG10201809099PA
Inventor
Michael Brines
Anthony Cerami
Original Assignee
Araim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Araim Pharmaceuticals Inc filed Critical Araim Pharmaceuticals Inc
Publication of SG10201809099PA publication Critical patent/SG10201809099PA/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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Abstract

TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE The present invention provides peptides and peptide analogs that have tissue protective 5 activities while having little or no potentially undesirable hematopoietic effects. The peptides and peptide analogs are useful in preventing and treating a variety of diseases and disorders associated with tissue damage. Fig. 1 10
SG10201809099PA 2013-07-17 2014-07-16 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage SG10201809099PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361847455P 2013-07-17 2013-07-17

Publications (1)

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SG10201809099PA true SG10201809099PA (en) 2018-11-29

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SG10201809099PA SG10201809099PA (en) 2013-07-17 2014-07-16 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
SG11201600294QA SG11201600294QA (en) 2013-07-17 2014-07-16 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

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US (2) US20160168199A1 (en)
EP (1) EP3021863A4 (en)
JP (3) JP6479789B2 (en)
KR (1) KR20160052537A (en)
CN (1) CN105517561A (en)
AU (2) AU2014290116A1 (en)
CA (1) CA2918223A1 (en)
HK (1) HK1223298A1 (en)
IL (1) IL243551A0 (en)
MX (1) MX2016000448A (en)
SG (2) SG10201809099PA (en)
WO (1) WO2015009820A2 (en)
ZA (1) ZA201600362B (en)

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JP2019523633A (en) 2016-04-29 2019-08-29 アライム ファーマシューティカルズ,インコーポレーテッド Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage
KR102167641B1 (en) 2018-08-27 2020-10-19 주식회사 사이루스 Composition for growth-promoting cell containing erythropoietin-derived peptide
CA3112382A1 (en) 2018-09-10 2020-03-19 Cold Spring Harbor Laboratory Methods for treating pancreatitis
DE102022112056A1 (en) 2021-05-28 2022-12-01 Shimano Inc. COMPONENT FOR MAN-PROPELLED VEHICLE AND ELECTRICAL SYSTEM FOR MAN-PROPELLED VEHICLE

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CA2168261A1 (en) * 1993-07-28 1995-02-09 Mathew Alexander Vadas Haemopoietic growth factor antagonists
IL124015A0 (en) * 1998-04-08 1999-01-26 Yeda Res & Dev Pharmaceutical compositions comprising a protein
EP1296702A4 (en) * 2000-05-26 2005-05-11 Ortho Mcneil Pharm Inc Neuroprotective peptides
CN1514733A (en) * 2001-02-06 2004-07-21 Ĭ��ר�����޹�˾ Modified erythropoietin (EPO) with reduced immunogenicity
MXPA05001452A (en) * 2002-08-09 2005-06-06 Merck Patent Gmbh T-cell epitopes in erythropoietin.
US7718363B2 (en) * 2003-04-25 2010-05-18 The Kenneth S. Warren Institute, Inc. Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds
KR20200072568A (en) * 2005-08-05 2020-06-22 아라임 파마슈티칼즈, 인크. Tissue protective peptides and uses thereof
WO2008065372A2 (en) * 2006-11-28 2008-06-05 Nautilus Biotech, S.A. Modified erythropoietin polypeptides and uses thereof for treatment
AU2008328754B2 (en) * 2007-11-29 2015-04-16 Molecular Health Gmbh Novel tissue protective erythropoietin receptor (NEPOR) and methods of use
SG188161A1 (en) * 2008-01-22 2013-03-28 Araim Pharmaceuticals Inc Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
WO2011022056A2 (en) * 2009-08-18 2011-02-24 Medical College Of Georgia Research Institute, Inc. PEPTIDE MODULATORS OF THE δPKC INTERACTION WITH THE D SUBUNIT OF F1FO ATP SYNTHASE/ATPASE AND USES THEREOF

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MX2016000448A (en) 2016-05-12
SG11201600294QA (en) 2016-02-26
WO2015009820A3 (en) 2015-04-09
US20210107942A1 (en) 2021-04-15
CA2918223A1 (en) 2015-01-22
KR20160052537A (en) 2016-05-12
CN105517561A (en) 2016-04-20
JP2021090447A (en) 2021-06-17
JP6479789B2 (en) 2019-03-13
EP3021863A2 (en) 2016-05-25
JP2016531105A (en) 2016-10-06
AU2014290116A1 (en) 2016-02-11
WO2015009820A2 (en) 2015-01-22
JP2019112406A (en) 2019-07-11
IL243551A0 (en) 2016-03-31
HK1223298A1 (en) 2017-07-28
ZA201600362B (en) 2020-05-27
US20160168199A1 (en) 2016-06-16
AU2020200352A1 (en) 2020-02-06
EP3021863A4 (en) 2017-01-04

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