SG10201803999UA - Recombinant factor viii formulations - Google Patents
Recombinant factor viii formulationsInfo
- Publication number
- SG10201803999UA SG10201803999UA SG10201803999UA SG10201803999UA SG10201803999UA SG 10201803999U A SG10201803999U A SG 10201803999UA SG 10201803999U A SG10201803999U A SG 10201803999UA SG 10201803999U A SG10201803999U A SG 10201803999UA SG 10201803999U A SG10201803999U A SG 10201803999UA
- Authority
- SG
- Singapore
- Prior art keywords
- factor viii
- recombinant factor
- formulations
- viii formulations
- recombinant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Abstract
RECOMBINANT FACTOR VIII FORMULATIONS Provided are liquid and lyophilized recombinant Factor VIII formulations, including formulations for polymer-conjugated FVIII such as PEGylated Factor VIII. FIGURE 18
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361799495P | 2013-03-15 | 2013-03-15 | |
US201361869191P | 2013-08-23 | 2013-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201803999UA true SG10201803999UA (en) | 2018-06-28 |
Family
ID=51580768
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201803999UA SG10201803999UA (en) | 2013-03-15 | 2014-03-11 | Recombinant factor viii formulations |
SG11201507618YA SG11201507618YA (en) | 2013-03-15 | 2014-03-11 | Recombinant factor viii formulations |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507618YA SG11201507618YA (en) | 2013-03-15 | 2014-03-11 | Recombinant factor viii formulations |
Country Status (17)
Country | Link |
---|---|
US (1) | US20160030524A1 (en) |
EP (1) | EP2970430A4 (en) |
JP (1) | JP2016518321A (en) |
KR (1) | KR20150132449A (en) |
CN (1) | CN105209487A (en) |
AU (1) | AU2014237111B2 (en) |
BR (1) | BR112015022730A2 (en) |
CA (1) | CA2905739A1 (en) |
HK (1) | HK1213273A1 (en) |
MX (1) | MX2015012905A (en) |
PE (1) | PE20160121A1 (en) |
RU (1) | RU2015144076A (en) |
SG (2) | SG10201803999UA (en) |
TW (1) | TW201521761A (en) |
UY (1) | UY35412A (en) |
WO (1) | WO2014150477A1 (en) |
ZA (1) | ZA201507684B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3247400A1 (en) * | 2015-01-18 | 2017-11-29 | Biogen MA Inc. | Formulations and screening of biological therapeutic agents |
TWI777175B (en) | 2015-11-13 | 2022-09-11 | 日商武田藥品工業股份有限公司 | Viral vectors encoding recombinant fviii variants with increased expression for gene therapy of hemophilia a |
TW202039546A (en) | 2019-01-16 | 2020-11-01 | 美商巴克斯歐塔公司 | Viral vectors encoding recombinant fviii variants with increased expression for gene therapy of hemophilia a |
US20220305089A1 (en) * | 2019-08-16 | 2022-09-29 | Octapharma Ag | Stabilizing buffer for factor viii and vwf |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5763401A (en) * | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
EP1152450A4 (en) * | 1999-02-01 | 2004-04-14 | Nippon Electric Glass Co | Cathode-ray tube and its production method |
US6586573B1 (en) * | 1999-02-22 | 2003-07-01 | Baxter International Inc. | Albumin-free Factor VIII formulations |
WO2002103024A2 (en) * | 2001-06-14 | 2002-12-27 | The Scripps Research Institute | Stabilized proteins with engineered disulfide bonds |
GB0207092D0 (en) * | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
MX2007005466A (en) * | 2004-11-12 | 2007-10-19 | Bayer Healthcare Llc | Site-directed modification of fviii. |
AU2007245190B2 (en) * | 2006-03-31 | 2011-07-21 | Takeda Pharmaceutical Company Limited | Pegylated factor VIII |
ES2706296T3 (en) * | 2008-11-07 | 2019-03-28 | Univ Connecticut | Formulations of Factor VIII |
WO2010083536A1 (en) * | 2009-01-19 | 2010-07-22 | Bayer Healthcare Llc | Protein conjugate having an endopeptidase-cleavable bioprotective moiety |
-
2014
- 2014-03-11 CA CA2905739A patent/CA2905739A1/en not_active Abandoned
- 2014-03-11 BR BR112015022730A patent/BR112015022730A2/en not_active IP Right Cessation
- 2014-03-11 PE PE2015002012A patent/PE20160121A1/en not_active Application Discontinuation
- 2014-03-11 AU AU2014237111A patent/AU2014237111B2/en not_active Ceased
- 2014-03-11 CN CN201480025467.XA patent/CN105209487A/en active Pending
- 2014-03-11 KR KR1020157029441A patent/KR20150132449A/en not_active Application Discontinuation
- 2014-03-11 EP EP14770228.6A patent/EP2970430A4/en not_active Withdrawn
- 2014-03-11 SG SG10201803999UA patent/SG10201803999UA/en unknown
- 2014-03-11 WO PCT/US2014/023357 patent/WO2014150477A1/en active Application Filing
- 2014-03-11 JP JP2016501214A patent/JP2016518321A/en active Pending
- 2014-03-11 US US14/774,191 patent/US20160030524A1/en not_active Abandoned
- 2014-03-11 RU RU2015144076A patent/RU2015144076A/en not_active Application Discontinuation
- 2014-03-11 SG SG11201507618YA patent/SG11201507618YA/en unknown
- 2014-03-11 MX MX2015012905A patent/MX2015012905A/en unknown
- 2014-03-13 UY UY0001035412A patent/UY35412A/en not_active Application Discontinuation
- 2014-03-13 TW TW103109012A patent/TW201521761A/en unknown
-
2015
- 2015-10-14 ZA ZA2015/07684A patent/ZA201507684B/en unknown
-
2016
- 2016-02-04 HK HK16101334.5A patent/HK1213273A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2970430A1 (en) | 2016-01-20 |
JP2016518321A (en) | 2016-06-23 |
ZA201507684B (en) | 2017-06-28 |
SG11201507618YA (en) | 2015-10-29 |
KR20150132449A (en) | 2015-11-25 |
MX2015012905A (en) | 2016-06-16 |
WO2014150477A1 (en) | 2014-09-25 |
AU2014237111A1 (en) | 2015-10-08 |
BR112015022730A2 (en) | 2017-10-31 |
EP2970430A4 (en) | 2017-01-11 |
CA2905739A1 (en) | 2014-09-25 |
PE20160121A1 (en) | 2016-03-03 |
CN105209487A (en) | 2015-12-30 |
HK1213273A1 (en) | 2016-06-30 |
UY35412A (en) | 2014-10-31 |
AU2014237111B2 (en) | 2018-06-21 |
RU2015144076A (en) | 2017-04-24 |
US20160030524A1 (en) | 2016-02-04 |
TW201521761A (en) | 2015-06-16 |
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