AR082913A2 - Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma - Google Patents

Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma

Info

Publication number
AR082913A2
AR082913A2 ARP110103258A ARP110103258A AR082913A2 AR 082913 A2 AR082913 A2 AR 082913A2 AR P110103258 A ARP110103258 A AR P110103258A AR P110103258 A ARP110103258 A AR P110103258A AR 082913 A2 AR082913 A2 AR 082913A2
Authority
AR
Argentina
Prior art keywords
effector
bronchodilator
pharmaceutical composition
prepare
related pathologies
Prior art date
Application number
ARP110103258A
Other languages
English (en)
Inventor
Tahir Ahmed
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26803748&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR082913(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Publication of AR082913A2 publication Critical patent/AR082913A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Una composición farmacéutica para tratar el asma y patologías relacionadas en un mamífero, que comprende cantidades terapéuticamente efectivas de un broncodilatador y un efector, en donde dicho efector es un polisacárido sulfatado que comprende de 1 a alrededor 10 residuos de azúcar. La composición puede comprender además un portador farmacéuticamente aceptable. Preferiblemente, el broncodilatador es un agonista andrenérgico b2 seleccionado del grupo integrado por salmeterol, formoterol, bambuterol, albuterol, terbutalina, pirbuterol, bitolterol, metaproterenol, isoetarina, e isoproterenol. En forma preferida, el efector es un polisacárido N-sulfatado, como por ejemplo la heparina que puede ser una heparina de peso molecular ultra bajo (ULMWH) o una heparina de bajo peso molecular (LMWH). Uso de un broncodilatador y un efector para preparar una composición farmacéutica de utilidad en un método para prevenir la tolerancia al broncodilatador en un mamífero que lo necesite, y que comprende la administración de cantidades terapéuticamente efectivas del broncodilatador y del efector, en donde dicho efector es un polisacárido sulfatado que comprende de 1 a alrededor de 10 residuos de azúcar. De esta manera se puede prevenir la tolerancia a los mencionados agonistas adrenérgicos b2, empleados como broncodilatadores.
ARP110103258A 1998-10-30 2011-09-07 Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma AR082913A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10650798P 1998-10-30 1998-10-30
US09/362,540 US6235725B1 (en) 1998-10-30 1999-07-28 Methods and compositions for the prevention of tolerance to medications

Publications (1)

Publication Number Publication Date
AR082913A2 true AR082913A2 (es) 2013-01-16

Family

ID=26803748

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP990105443A AR023911A1 (es) 1998-10-30 1999-10-28 Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma
ARP110103258A AR082913A2 (es) 1998-10-30 2011-09-07 Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP990105443A AR023911A1 (es) 1998-10-30 1999-10-28 Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma

Country Status (25)

Country Link
US (1) US6235725B1 (es)
EP (1) EP1124563B1 (es)
JP (1) JP4585121B2 (es)
CN (2) CN1329496A (es)
AR (2) AR023911A1 (es)
AT (1) ATE277621T1 (es)
AU (1) AU760119B2 (es)
BR (1) BR9915818A (es)
CA (1) CA2348926C (es)
CO (1) CO5160320A1 (es)
CY (1) CY1107493T1 (es)
CZ (1) CZ297914B6 (es)
DE (1) DE69920734T2 (es)
ES (1) ES2228173T3 (es)
HK (1) HK1041596A1 (es)
HU (1) HUP0302492A3 (es)
IL (2) IL142865A0 (es)
IS (1) IS2321B (es)
NO (1) NO333194B1 (es)
NZ (1) NZ511399A (es)
PL (1) PL195592B1 (es)
PT (1) PT1124563E (es)
SK (1) SK285150B6 (es)
TW (1) TW565451B (es)
WO (1) WO2000025723A2 (es)

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Also Published As

Publication number Publication date
AR023911A1 (es) 2002-09-04
SK5902001A3 (en) 2002-07-02
CZ20011518A3 (cs) 2002-04-17
NO20012097D0 (no) 2001-04-27
US6235725B1 (en) 2001-05-22
CN1572303A (zh) 2005-02-02
JP2002535245A (ja) 2002-10-22
SK285150B6 (sk) 2006-07-07
TW565451B (en) 2003-12-11
EP1124563A4 (en) 2002-01-02
WO2000025723A3 (en) 2000-07-27
PT1124563E (pt) 2005-01-31
ATE277621T1 (de) 2004-10-15
IL142865A0 (en) 2002-03-10
WO2000025723A2 (en) 2000-05-11
ES2228173T3 (es) 2005-04-01
DE69920734D1 (de) 2004-11-04
PL195592B1 (pl) 2007-10-31
NZ511399A (en) 2004-09-24
CA2348926C (en) 2011-08-23
BR9915818A (pt) 2002-06-18
CY1107493T1 (el) 2013-03-13
AU760119B2 (en) 2003-05-08
DE69920734T2 (de) 2005-10-06
AU1205100A (en) 2000-05-22
HK1041596A1 (zh) 2002-07-12
IS2321B (is) 2007-12-15
IL142865A (en) 2006-07-05
JP4585121B2 (ja) 2010-11-24
EP1124563A2 (en) 2001-08-22
CN100352448C (zh) 2007-12-05
CO5160320A1 (es) 2002-05-30
NO333194B1 (no) 2013-04-02
CA2348926A1 (en) 2000-05-11
PL364727A1 (en) 2004-12-13
CZ297914B6 (cs) 2007-04-25
IS5928A (is) 2001-04-27
HUP0302492A3 (en) 2005-05-30
NO20012097L (no) 2001-06-15
CN1329496A (zh) 2002-01-02
EP1124563B1 (en) 2004-09-29
HUP0302492A2 (hu) 2003-11-28

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