BR9808641B1 - processo para preparação de uma forma de dosagem sólida, oral de rápida desintegração de uma substáncia farmaceuticamente ativa que possui um sabor inaceitável. - Google Patents

processo para preparação de uma forma de dosagem sólida, oral de rápida desintegração de uma substáncia farmaceuticamente ativa que possui um sabor inaceitável.

Info

Publication number
BR9808641B1
BR9808641B1 BRPI9808641-3A BR9808641A BR9808641B1 BR 9808641 B1 BR9808641 B1 BR 9808641B1 BR 9808641 A BR9808641 A BR 9808641A BR 9808641 B1 BR9808641 B1 BR 9808641B1
Authority
BR
Brazil
Prior art keywords
active substance
pharmaceutically active
rapidly disintegrating
lipid
dosage form
Prior art date
Application number
BRPI9808641-3A
Other languages
English (en)
Other versions
BR9808641A (pt
Inventor
Leon Grother
Michael Hall
Douglas Bryans
Richard Green
Patrick Kearney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR9808641A publication Critical patent/BR9808641A/pt
Publication of BR9808641B1 publication Critical patent/BR9808641B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI9808641-3A 1997-02-12 1998-02-12 processo para preparação de uma forma de dosagem sólida, oral de rápida desintegração de uma substáncia farmaceuticamente ativa que possui um sabor inaceitável. BR9808641B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9702799.9A GB9702799D0 (en) 1997-02-12 1997-02-12 Process for preparing solid pharmaceutical dosage forms
PCT/GB1998/000425 WO1998035656A1 (en) 1997-02-12 1998-02-12 Process for preparing solid pharmaceutical dosage forms

Publications (2)

Publication Number Publication Date
BR9808641A BR9808641A (pt) 2000-05-23
BR9808641B1 true BR9808641B1 (pt) 2009-05-05

Family

ID=10807446

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9808641-3A BR9808641B1 (pt) 1997-02-12 1998-02-12 processo para preparação de uma forma de dosagem sólida, oral de rápida desintegração de uma substáncia farmaceuticamente ativa que possui um sabor inaceitável.

Country Status (13)

Country Link
US (1) US6156339A (pt)
EP (1) EP0973506B1 (pt)
JP (1) JP4763105B2 (pt)
AT (1) ATE219664T1 (pt)
AU (1) AU6221298A (pt)
BR (1) BR9808641B1 (pt)
CA (1) CA2278785C (pt)
DE (1) DE69806236T2 (pt)
DK (1) DK0973506T3 (pt)
ES (1) ES2178154T3 (pt)
GB (1) GB9702799D0 (pt)
PT (1) PT973506E (pt)
WO (1) WO1998035656A1 (pt)

Families Citing this family (24)

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DE19853737C2 (de) * 1998-11-21 2003-03-06 Lohmann Therapie Syst Lts Verfahren zum Spenden von flächigen Gebilden
IT1315252B1 (it) * 1999-10-21 2003-02-03 Truffini & Regge Farmaceutici Compresse gastroresistenti ad uso alimentare o dietetico ottenutemediante grassi miscelati alla massa
US6589955B2 (en) 2001-06-20 2003-07-08 Bristol-Myers Squibb Company Pediatric formulation of gatifloxacin
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US20040029843A1 (en) * 2002-06-20 2004-02-12 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
US20040156894A1 (en) * 2003-02-07 2004-08-12 Grother Leon Paul Use of edible acids in fast-dispersing pharmaceutical solid dosage forms
US20040224024A1 (en) * 2003-04-23 2004-11-11 Massachusetts Institute Of Technology Controlled drug release formulations containing polyion complexes
EP1624862B1 (en) 2003-05-08 2014-12-31 Nektar Therapeutics Particulate materials
EP1670441A4 (en) * 2003-10-07 2012-05-02 Andrx Pharmaceuticals Llc FAST RESOLUTION FORMULATION
EP2322197A2 (en) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmaceutical compositions including low dosages of desmopressin
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
AR061485A1 (es) * 2006-06-15 2008-08-27 Serenex Inc Composiciones estabilizadas de tetraciclina
US8889184B2 (en) * 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
EP2120875B1 (en) 2007-02-11 2018-07-11 Map Pharmaceuticals Inc. Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
EP2467130A2 (en) * 2009-08-17 2012-06-27 Waxtabs (Pty) Ltd Process for manufacturing tablets by using a fluent and settable matrix, and tablets obtained therewith
WO2011026080A1 (en) 2009-08-31 2011-03-03 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam, processes for preparation, and use to treat arthritis and/or pain
FR2950807B1 (fr) * 2009-10-06 2012-02-03 Lvmh Rech Composition cosmetique contenant des liposomes encapsules dans un compose oxazolidin-2-one
BR112019013503A2 (pt) 2016-12-31 2020-01-07 Bioxcel Therapeutics, Inc. Uso de dexmedetomidina sublingual para o tratamento da agitação
CN114983981A (zh) 2018-06-27 2022-09-02 比奥克斯塞尔医疗股份有限公司 含右美托咪定的膜制剂及其制造方法
CA3145388A1 (en) 2019-07-19 2021-01-28 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
FR2515035A1 (fr) * 1981-10-26 1983-04-29 Rhone Poulenc Sante Nouvelle forme galenique solide pour administration par voie orale et son procede de fabrication
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
WO1985005029A1 (en) * 1984-05-09 1985-11-21 Medaphore Inc. Oral insulin and a method of making the same
JPS62265234A (ja) * 1986-05-14 1987-11-18 Showa Yakuhin Kako Kk 苦味抑制製剤組成物
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
EP0409432A3 (en) * 1989-07-20 1991-12-11 Warner-Lambert Company Confectionery delivery system
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
ATE245023T1 (de) * 1991-05-28 2003-08-15 Mcneil Ppc Inc Kaubare zusammensetzung zur arzneimittelfreisetzung
US5407921A (en) * 1993-07-01 1995-04-18 Kao Corporation Method for suppressing bitter taste
JP3776941B2 (ja) * 1993-12-24 2006-05-24 塩野義製薬株式会社 味覚の改善された顆粒剤及びその製造方法
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JP3325116B2 (ja) * 1994-04-28 2002-09-17 花王株式会社 苦味低減化剤、その製造法、苦味低減化法、そして苦味低減化組成物
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
CA2134611C (en) * 1994-10-28 2002-12-24 Richard John Yarwood Process for preparing solid pharmaceutical dosage forms
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances

Also Published As

Publication number Publication date
US6156339A (en) 2000-12-05
ES2178154T3 (es) 2002-12-16
JP4763105B2 (ja) 2011-08-31
DK0973506T3 (da) 2002-07-22
BR9808641A (pt) 2000-05-23
WO1998035656A1 (en) 1998-08-20
JP2001511800A (ja) 2001-08-14
EP0973506A1 (en) 2000-01-26
GB9702799D0 (en) 1997-04-02
ATE219664T1 (de) 2002-07-15
DE69806236D1 (de) 2002-08-01
PT973506E (pt) 2002-10-31
DE69806236T2 (de) 2003-02-20
EP0973506B1 (en) 2002-06-26
CA2278785A1 (en) 1998-08-20
AU6221298A (en) 1998-09-08
CA2278785C (en) 2005-08-09

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