ATE219664T1 - Verfahren zur herstellung fester pharmazeutischer dosisformen - Google Patents

Verfahren zur herstellung fester pharmazeutischer dosisformen

Info

Publication number
ATE219664T1
ATE219664T1 AT98904265T AT98904265T ATE219664T1 AT E219664 T1 ATE219664 T1 AT E219664T1 AT 98904265 T AT98904265 T AT 98904265T AT 98904265 T AT98904265 T AT 98904265T AT E219664 T1 ATE219664 T1 AT E219664T1
Authority
AT
Austria
Prior art keywords
lipid
active substance
pharmaceutically active
carrier
solid pharmaceutical
Prior art date
Application number
AT98904265T
Other languages
English (en)
Inventor
Leon Grother
Michael Hall
Douglas Bryans
Richard Green
Patrick Kearney
Original Assignee
Scherer Technologies Inc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P
Application granted granted Critical
Publication of ATE219664T1 publication Critical patent/ATE219664T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98904265T 1997-02-12 1998-02-12 Verfahren zur herstellung fester pharmazeutischer dosisformen ATE219664T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9702799.9A GB9702799D0 (en) 1997-02-12 1997-02-12 Process for preparing solid pharmaceutical dosage forms
PCT/GB1998/000425 WO1998035656A1 (en) 1997-02-12 1998-02-12 Process for preparing solid pharmaceutical dosage forms

Publications (1)

Publication Number Publication Date
ATE219664T1 true ATE219664T1 (de) 2002-07-15

Family

ID=10807446

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904265T ATE219664T1 (de) 1997-02-12 1998-02-12 Verfahren zur herstellung fester pharmazeutischer dosisformen

Country Status (13)

Country Link
US (1) US6156339A (de)
EP (1) EP0973506B1 (de)
JP (1) JP4763105B2 (de)
AT (1) ATE219664T1 (de)
AU (1) AU6221298A (de)
BR (1) BR9808641B1 (de)
CA (1) CA2278785C (de)
DE (1) DE69806236T2 (de)
DK (1) DK0973506T3 (de)
ES (1) ES2178154T3 (de)
GB (1) GB9702799D0 (de)
PT (1) PT973506E (de)
WO (1) WO1998035656A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19853737C2 (de) * 1998-11-21 2003-03-06 Lohmann Therapie Syst Lts Verfahren zum Spenden von flächigen Gebilden
IT1315252B1 (it) * 1999-10-21 2003-02-03 Truffini & Regge Farmaceutici Compresse gastroresistenti ad uso alimentare o dietetico ottenutemediante grassi miscelati alla massa
US6589955B2 (en) 2001-06-20 2003-07-08 Bristol-Myers Squibb Company Pediatric formulation of gatifloxacin
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
AU2003256284A1 (en) * 2002-06-20 2004-01-06 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
US20040156894A1 (en) * 2003-02-07 2004-08-12 Grother Leon Paul Use of edible acids in fast-dispersing pharmaceutical solid dosage forms
US20040224024A1 (en) * 2003-04-23 2004-11-11 Massachusetts Institute Of Technology Controlled drug release formulations containing polyion complexes
BRPI0409962A (pt) 2003-05-08 2006-04-25 Nektar Therapeutics Uk Ltd co-formulação particulada de uma substáncia ativa e um excipiente, composição farmacêutica ou nutricêutrica, produto farmacêutico ou nutricêutico, método para preparar uma co-formulação particulada de uma substáncia ativa e um excipiente, e, uso de uma substáncia ativa e um excipiente
CA2785138A1 (en) * 2003-10-07 2005-04-21 Andrx Pharmaceuticals Llc Rapidly disintegrating formulation
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
CN1878563A (zh) 2003-11-10 2006-12-13 西摩·H·费恩 包含低剂量去氨加压素的药物组合物
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
TW200815020A (en) * 2006-06-15 2008-04-01 Serenex Inc Stabilized tetracycline compositions
US8889184B2 (en) * 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
PT2425820E (pt) 2007-02-11 2015-08-04 Map Pharmaceuticals Inc Método de administração terapêutica de dhe para permitir o rápido alívio das enxaquecas ao mesmo tempo que minimiza o perfil de efeitos secundários
AU2010284028A1 (en) * 2009-08-17 2012-03-29 Waxtabs (Pty) Ltd Process for manufacturing tablets by using a fluent and settable matrix, and tablets obtained therewith
WO2011026080A1 (en) 2009-08-31 2011-03-03 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam, processes for preparation, and use to treat arthritis and/or pain
FR2950807B1 (fr) * 2009-10-06 2012-02-03 Lvmh Rech Composition cosmetique contenant des liposomes encapsules dans un compose oxazolidin-2-one
CN110337290A (zh) 2016-12-31 2019-10-15 比奥克斯塞尔医疗股份有限公司 舌下右旋美托咪啶用于治疗激越的用途
CN115154440A (zh) 2018-06-27 2022-10-11 比奥克斯塞尔医疗股份有限公司 含右美托咪定的膜制剂及其制造方法
EP3999058A4 (de) 2019-07-19 2023-05-03 Bioxcel Therapeutics, Inc. Behandlungsschemata für nicht-sedierendes dexmedetomidin
US20240189241A1 (en) * 2021-04-01 2024-06-13 R.P. Scherer Technologies, Llc Phospholipids as anion chelating agents in pharmaceutical formulations
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515035A1 (fr) * 1981-10-26 1983-04-29 Rhone Poulenc Sante Nouvelle forme galenique solide pour administration par voie orale et son procede de fabrication
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
WO1985005029A1 (en) * 1984-05-09 1985-11-21 Medaphore Inc. Oral insulin and a method of making the same
JPS62265234A (ja) * 1986-05-14 1987-11-18 Showa Yakuhin Kako Kk 苦味抑制製剤組成物
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
EP0409432A3 (en) * 1989-07-20 1991-12-11 Warner-Lambert Company Confectionery delivery system
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
AU653423B2 (en) * 1991-05-28 1994-09-29 Mcneil-Ppc, Inc. Chewable drug-delivery composition
US5407921A (en) * 1993-07-01 1995-04-18 Kao Corporation Method for suppressing bitter taste
JP3776941B2 (ja) * 1993-12-24 2006-05-24 塩野義製薬株式会社 味覚の改善された顆粒剤及びその製造方法
JPH07267850A (ja) * 1994-03-28 1995-10-17 Eisai Co Ltd 不快味を防止した医薬組成物及びその製造方法
JP3325116B2 (ja) * 1994-04-28 2002-09-17 花王株式会社 苦味低減化剤、その製造法、苦味低減化法、そして苦味低減化組成物
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
GB9421837D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms

Also Published As

Publication number Publication date
AU6221298A (en) 1998-09-08
EP0973506B1 (de) 2002-06-26
PT973506E (pt) 2002-10-31
DE69806236D1 (de) 2002-08-01
GB9702799D0 (en) 1997-04-02
ES2178154T3 (es) 2002-12-16
DK0973506T3 (da) 2002-07-22
CA2278785A1 (en) 1998-08-20
WO1998035656A1 (en) 1998-08-20
DE69806236T2 (de) 2003-02-20
BR9808641B1 (pt) 2009-05-05
EP0973506A1 (de) 2000-01-26
JP2001511800A (ja) 2001-08-14
US6156339A (en) 2000-12-05
JP4763105B2 (ja) 2011-08-31
BR9808641A (pt) 2000-05-23
CA2278785C (en) 2005-08-09

Similar Documents

Publication Publication Date Title
ATE219664T1 (de) Verfahren zur herstellung fester pharmazeutischer dosisformen
GB9421837D0 (en) Process for preparing solid pharmaceutical dosage forms
DE69520036D1 (de) Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen
CA2366702A1 (en) Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
CA2227761A1 (en) Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizers
MY129798A (en) Process for preparing a pharmaceutical composition
MX9306393A (es) Composiciones de ranitidina substancialmente libres de sabor amargo, proceso para su preparacion y composiciones farmaceuticas que las contienen.
MA26471A1 (fr) Derives d'acide arylsulfonylaminohydroxamique, procede pour leur preparation et compositions pharmaceutiques les contenant.
NO20002306D0 (no) FremgangsmÕte ved økning av absorpsjon og transport av lipid- oppløselige forbindelser ved Õ bruke strukturelle glycerider
AU8178601A (en) Sustained release pharmaceutical compositions for the parenteral administration of biologically active hydrophilic compounds
ATE410162T1 (de) Verfahren zur herstellung einer fein selbstemulgierbaren pharmazeutischen zusammensetzung
DE59509566D1 (de) Pharmazeutische zubereitung mit einem hydrophoben wirkstoff und einem brausesystem, sowie verfahren zur herstellung der zubereitung
ATE226065T1 (de) Feste instant-release-darreichungsformen und verfahren zu ihrer herstellung
ATE193297T1 (de) Wasserlösliche derivate epipodophyllotoxine, verfahren zu ihrer herstellung, ihre verwendung als medikament und ihre verwendung zur herstellung eines antikrebsmittels
NO975371D0 (no) Farmasöytisk sammensetning fremstilt ved tilföring av en smakstilsetningsbærer til et medikament
EP0781135A4 (de) Codein enthaltende formulierungen
UA5654C2 (uk) Спосіб одержання липосомального препарату
RU93049678A (ru) Устойчивый водорастворимый ветеринарный препарат и способ его получения

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification