ES2153498T3 - Proceso para preparar formas de dosificacion farmaceutica solidas. - Google Patents

Proceso para preparar formas de dosificacion farmaceutica solidas.

Info

Publication number
ES2153498T3
ES2153498T3 ES95934712T ES95934712T ES2153498T3 ES 2153498 T3 ES2153498 T3 ES 2153498T3 ES 95934712 T ES95934712 T ES 95934712T ES 95934712 T ES95934712 T ES 95934712T ES 2153498 T3 ES2153498 T3 ES 2153498T3
Authority
ES
Spain
Prior art keywords
water
active substance
pharmaceutically active
dosage forms
pharmaceutical dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95934712T
Other languages
English (en)
Inventor
Richard John Yarwood
Patrick Kearney
Andrew Roy Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Application granted granted Critical
Publication of ES2153498T3 publication Critical patent/ES2153498T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D25/00—Filters formed by clamping together several filtering elements or parts of such elements
    • B01D25/12—Filter presses, i.e. of the plate or plate and frame type
    • B01D25/176—Filter presses, i.e. of the plate or plate and frame type attaching the filter element to the filter press plates, e.g. around the central feed hole in the plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UN PROCESO PARA LA PREPARACION DE UNA FORMA DE DOSIFICACION ORAL, SOLIDA, RAPIDAMENTE DESINTEGRABLE DE UNA SUSTANCIAS FARMACOLOGICAMENTE ACTIVA QUE TENGA UN SABOR NO ACEPTABLE, EL PROCESO COMPRENDE LA FORMACION DE UNA SOLUCION O DE UNA SUSPENSION EN UN SOLVENTE DE UNA FORMA DE UNA SUSTANCIA FARMACOLOGICAMENTE ACTIVA QUE SEA MENOS SOLUBLE EN AGUA Y MAS AGRADABLE AL GUSTO QUE LA FORMA CON EL SABOR INACEPTABLE JUNTO CON UN MATERIAL PORTADORA SOLUBLE O DISPERSIBLE EN AGUA, FORMANDO UNIDADES DISCRETAS DE LA SUSPENSION O SOLUCION Y ELIMINANDO EL SOLVENTE DE LAS UNIDADES DISCRETAS BAJO CONDICIONES MEDIANTE LAS CUALES SE FORME UNA RED DEL MATERIAL PORTADOR QUE LLEVA UNA DOSIS DE LA FORMA MENOS SOLUBLE Y MAS AGRADABLE AL GUSTO DE LA SUBSTANCIA FARMACOLOGICAMENTE ACTIVA.
ES95934712T 1994-10-28 1995-10-20 Proceso para preparar formas de dosificacion farmaceutica solidas. Expired - Lifetime ES2153498T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/330,936 US5738875A (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
CA002134611A CA2134611C (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms
GB9421837A GB9421837D0 (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms

Publications (1)

Publication Number Publication Date
ES2153498T3 true ES2153498T3 (es) 2001-03-01

Family

ID=27169885

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95934712T Expired - Lifetime ES2153498T3 (es) 1994-10-28 1995-10-20 Proceso para preparar formas de dosificacion farmaceutica solidas.

Country Status (16)

Country Link
US (1) US5738875A (es)
EP (1) EP0737065B1 (es)
JP (2) JP3839845B2 (es)
CN (1) CN1204877C (es)
AT (1) ATE198150T1 (es)
AU (1) AU3702895A (es)
CA (1) CA2134611C (es)
DE (1) DE69519664T2 (es)
DK (1) DK0737065T3 (es)
ES (1) ES2153498T3 (es)
GB (1) GB9421837D0 (es)
GR (1) GR3035194T3 (es)
MX (1) MX9602514A (es)
PT (1) PT737065E (es)
WO (1) WO1996013252A1 (es)
ZA (1) ZA959073B (es)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5738875A (en) * 1994-10-28 1998-04-14 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms
US8071128B2 (en) * 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
BR0007360A (pt) * 1999-12-23 2001-08-14 Johnson & Johnson Composição de liberação controlada
WO2001064202A2 (en) * 2000-03-01 2001-09-07 Euro-Celtique S.A. Tramadol for the treatment of functional gastrointestinal disorders
US6814978B2 (en) 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
CA2449731A1 (en) * 2001-06-07 2002-12-19 Tanabe Seiyaku Co., Ltd. Functional grain-containing preparations quickly disintegrated in the oral cavity
US20030153590A1 (en) * 2001-08-14 2003-08-14 Oy Contral Pharma Ltd Method of treating alcoholism or alcohol abuse
US20040258748A1 (en) * 2001-09-25 2004-12-23 Ashish Madan Process for the preparation of fast dissolving dosage form
CN1596100A (zh) * 2001-09-28 2005-03-16 麦克内尔-Ppc股份有限公司 可食用组合物及含可食用外壳的制剂
US9358214B2 (en) * 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
ATE516799T1 (de) * 2002-02-13 2011-08-15 Michael K Weibel Arzneimitteldosenform und -herstellungsverfahren
CA2478411C (en) * 2002-03-12 2010-09-28 Bristol-Myers Squibb Company Palatable oral suspension and method
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US7985422B2 (en) * 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040234579A1 (en) * 2003-05-22 2004-11-25 Mark D. Finke, Inc. Dietary supplements and methods of preparing and administering dietary supplements
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
US20050112196A1 (en) * 2003-10-07 2005-05-26 Jianbo Xie Rapidly disintegrating formulation
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
EP2322197A2 (en) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmaceutical compositions including low dosages of desmopressin
EP1582221A1 (en) 2004-03-31 2005-10-05 Chiesi S.A. Pharmaceutical oral compositions with a taste masking effect
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP1802285B1 (en) * 2004-10-21 2013-02-27 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
ITMI20042356A1 (it) * 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
US8697674B2 (en) * 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
US20070293580A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies
US20070293582A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US8545879B2 (en) 2009-08-31 2013-10-01 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam
TWI471146B (zh) 2009-12-02 2015-02-01 Aptalis Pharma Ltd 菲索特芬那定（ｆｅｘｏｆｅｎａｄｉｎｅ）微膠囊及包含其之組合物
US20110212171A1 (en) * 2010-01-08 2011-09-01 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
US10548839B2 (en) * 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
CA2819663C (en) 2010-12-02 2019-12-24 Aptalis Pharmatech, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
EP2968181B1 (en) 2013-03-15 2019-10-16 Aprecia Pharmaceuticals LLC Rapidly dispersible dosage form of topiramate
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
AU2014228990B2 (en) 2013-03-15 2017-02-02 Aprecia Pharmaceuticals LLC Rapid disperse dosage form containing levetiracetam
JP6463333B2 (ja) 2013-03-15 2019-01-30 アプレシア・ファーマスーティカルズ・カンパニー オキシカルバゼピンの急速分散性の剤形
WO2015105992A1 (en) 2014-01-10 2015-07-16 Mcneil-Ppc, Inc. Process for making tablet using radiofrequency and lossy coated particles
KR102193599B1 (ko) 2014-09-17 2020-12-21 스티어라이프 인디아 프라이빗 리미티드 발포성 조성물 및 이의 제조방법
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
IT201600078683A1 (it) * 2016-07-27 2018-01-27 Mattia Saporiti Matrice edibile per uso veterinario e zootecnico e relativo metodo di produzione
WO2018115888A1 (en) 2016-12-21 2018-06-28 N4 Pharma Uk Limited Novel formulations of aprepitant
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
EP3883546A1 (en) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
CN113490486A (zh) 2019-02-22 2021-10-08 康特伦英国斯温顿捷迪斯有限公司 最小化团聚、曝气和保持包含布洛芬的药物组合物的包衣
BR112021016408A2 (pt) * 2019-02-22 2021-10-13 Catalent U.K. Swindon Zydis Limited Minimização de aeração de suspensões durante mistura em linha
CN116018131A (zh) 2020-06-26 2023-04-25 阿普雷奇亚制药有限责任公司 具有内腔的快速口腔分散片剂
WO2022179635A1 (zh) * 2021-02-27 2022-09-01 北京兴源联合医药科技有限公司 一种β-烟酰胺单核苷酸冻干口服制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
CA1097233A (en) * 1977-07-20 1981-03-10 George K. E. Gregory Packages
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
IE53696B1 (en) * 1981-12-02 1989-01-18 Wyeth John & Brother Ltd Solid shaped articles
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
US5206025A (en) * 1989-05-24 1993-04-27 Rhone-Poulenc Sante Porous pharmaceutical form and its preparation
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5188825A (en) * 1989-12-28 1993-02-23 Iles Martin C Freeze-dried dosage forms and methods for preparing the same
WO1992017209A1 (en) * 1991-04-08 1992-10-15 Sumitomo Pharmaceuticals Company, Limited Porous solid preparation containing physiologically active protein substance
JP2807346B2 (ja) * 1991-12-24 1998-10-08 山之内製薬株式会社 口腔内崩壊製剤及びその製造法
US5298261A (en) * 1992-04-20 1994-03-29 Oregon Freeze Dry, Inc. Rapidly distintegrating tablet
JPH06298668A (ja) * 1993-02-18 1994-10-25 Takeda Chem Ind Ltd 経口用医薬組成物
US5382437A (en) * 1993-10-25 1995-01-17 Hunter Research Corporation Frozen liquified gas composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5738875A (en) * 1994-10-28 1998-04-14 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms

Also Published As

Publication number Publication date
CN1140407A (zh) 1997-01-15
US5738875A (en) 1998-04-14
EP0737065B1 (en) 2000-12-20
MX9602514A (es) 1997-05-31
DE69519664D1 (de) 2001-01-25
JPH09511256A (ja) 1997-11-11
ATE198150T1 (de) 2001-01-15
AU3702895A (en) 1996-05-23
WO1996013252A1 (en) 1996-05-09
GR3035194T3 (en) 2001-04-30
JP3839845B2 (ja) 2006-11-01
GB9421837D0 (en) 1994-12-14
EP0737065A1 (en) 1996-10-16
CA2134611A1 (en) 1996-04-29
JP2006111635A (ja) 2006-04-27
ZA959073B (en) 1996-05-22
DE69519664T2 (de) 2001-05-17
PT737065E (pt) 2001-04-30
DK0737065T3 (da) 2001-01-15
CN1204877C (zh) 2005-06-08
CA2134611C (en) 2002-12-24

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