AR023911A1 - Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma - Google Patents
Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la mismaInfo
- Publication number
- AR023911A1 AR023911A1 ARP990105443A ARP990105443A AR023911A1 AR 023911 A1 AR023911 A1 AR 023911A1 AR P990105443 A ARP990105443 A AR P990105443A AR P990105443 A ARP990105443 A AR P990105443A AR 023911 A1 AR023911 A1 AR 023911A1
- Authority
- AR
- Argentina
- Prior art keywords
- effector
- bronchodilator
- pharmaceutical composition
- prepare
- sulfated polysaccharide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una composicion farmacéutica para tratar el asma y patologías relacionadas en un mamífero, que comprende cantidades terapéuticamente efectivas de unbroncodilatador y un efector, en donde dicho efector es un polisacárido sulfatado que comprende de 1 aalrededor de 10 residuos de azucar. La composicion puedecomprender además un portador farmacéuticamente aceptable. Preferentemente, el broncodilatador es un agonista adrenérgico beta2 seleccionado del grupointegrado por salmeterol, formoterol, bambuterol, albuterol, terbutalina, pirbuterol, bitolterol, metaproterenol, isoetarina e isoproterenol. En formapreferida, el efector es un polisacárido N-sulfatado, como por ejemplo la heparina que puede ser una heparina de peso molecular ultra bajo (ULMWH) o unaheparina de bajo peso molecular (LMWH). Uso de un broncodilatador y un efector para preparar una composicion farmacéutica de utilidad en un método paraprevenir la tolerancia al broncodilatador en un mamífero que lo necesite, y que comprendela administracion de cantidades terapéuticamente efectivas delbroncodilatador y del efector, en donde dicho efector es un polisacárido sulfatado que comprende de 1 a alrededor de 10 residuos de azucar. De esta manera sepuede prevenir la tolerancia alos mencionados agonistas adrenérgicos beta2, empleados como broncodilatadores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10650798P | 1998-10-30 | 1998-10-30 | |
US09/362,540 US6235725B1 (en) | 1998-10-30 | 1999-07-28 | Methods and compositions for the prevention of tolerance to medications |
Publications (1)
Publication Number | Publication Date |
---|---|
AR023911A1 true AR023911A1 (es) | 2002-09-04 |
Family
ID=26803748
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990105443A AR023911A1 (es) | 1998-10-30 | 1999-10-28 | Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma |
ARP110103258A AR082913A2 (es) | 1998-10-30 | 2011-09-07 | Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP110103258A AR082913A2 (es) | 1998-10-30 | 2011-09-07 | Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma |
Country Status (25)
Country | Link |
---|---|
US (1) | US6235725B1 (es) |
EP (1) | EP1124563B1 (es) |
JP (1) | JP4585121B2 (es) |
CN (2) | CN100352448C (es) |
AR (2) | AR023911A1 (es) |
AT (1) | ATE277621T1 (es) |
AU (1) | AU760119B2 (es) |
BR (1) | BR9915818A (es) |
CA (1) | CA2348926C (es) |
CO (1) | CO5160320A1 (es) |
CY (1) | CY1107493T1 (es) |
CZ (1) | CZ297914B6 (es) |
DE (1) | DE69920734T2 (es) |
ES (1) | ES2228173T3 (es) |
HK (1) | HK1041596A1 (es) |
HU (1) | HUP0302492A3 (es) |
IL (2) | IL142865A0 (es) |
IS (1) | IS2321B (es) |
NO (1) | NO333194B1 (es) |
NZ (1) | NZ511399A (es) |
PL (1) | PL195592B1 (es) |
PT (1) | PT1124563E (es) |
SK (1) | SK285150B6 (es) |
TW (1) | TW565451B (es) |
WO (1) | WO2000025723A2 (es) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9902689D0 (en) * | 1999-02-08 | 1999-03-31 | Novartis Ag | Organic compounds |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
DZ3477A1 (es) * | 2000-10-12 | 2002-04-18 | ||
US6667344B2 (en) * | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
US20030140920A1 (en) * | 2001-10-26 | 2003-07-31 | Dey L.P. | Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma |
JP2003221335A (ja) | 2001-10-26 | 2003-08-05 | Dey Lp | 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法 |
US20030203930A1 (en) * | 2001-10-26 | 2003-10-30 | Imtiaz Chaudry | Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
US20030191151A1 (en) * | 2001-10-26 | 2003-10-09 | Imtiaz Chaudry | Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
US6702997B2 (en) | 2001-10-26 | 2004-03-09 | Dey, L.P. | Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma |
CA2516318C (en) * | 2002-02-18 | 2011-07-19 | University Of Southampton | Use of glycosaminoglycans such as heparin for the treatment of respiratory disorders such as copd |
EP1513502B1 (en) * | 2002-02-18 | 2015-12-30 | Ockham Biotech Limited | Combination therapy for respiratory disorders |
CA2516322C (en) * | 2002-02-18 | 2013-10-15 | University Of Southampton | Glycosaminoglycan-dnase combination therapy |
DE60318938T2 (de) | 2002-03-20 | 2009-01-22 | Mannkind Corp., Valencia | Inhalationsgerät |
CA2483271A1 (en) * | 2002-04-25 | 2003-11-06 | Momenta Pharmaceuticals, Inc. | Methods and products for mucosal delivery |
US20040023935A1 (en) * | 2002-08-02 | 2004-02-05 | Dey, L.P. | Inhalation compositions, methods of use thereof, and process for preparation of same |
US7763280B2 (en) * | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
US20040109826A1 (en) * | 2002-12-06 | 2004-06-10 | Dey, L.P. | Stabilized albuterol compositions and method of preparation thereof |
JP4851185B2 (ja) | 2003-05-16 | 2012-01-11 | ジェレックスインターナショナル株式会社 | アレルギー症状抑制剤及び空気濾過フィルター |
TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
US20050043343A1 (en) * | 2003-07-28 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a PDE IV inhibitor |
ES2385934T3 (es) | 2004-08-20 | 2012-08-03 | Mannkind Corporation | Catálisis de la síntesis de dicetopiperazina. |
EP2314298B1 (en) | 2004-08-23 | 2015-05-27 | MannKind Corporation | Microparticles comprising diketopiperazine salts for drug delivery |
KR20160022404A (ko) | 2005-09-14 | 2016-02-29 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
MX2008010721A (es) | 2006-02-22 | 2008-09-01 | Mannkind Corp | Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo. |
EP3281663B8 (en) | 2008-06-13 | 2022-09-21 | MannKind Corporation | Breath powered dry powder inhaler for drug delivery |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
MX2010014240A (es) | 2008-06-20 | 2011-03-25 | Mankind Corp | Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion. |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
US8551528B2 (en) | 2009-06-12 | 2013-10-08 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
WO2011133687A2 (en) * | 2010-04-20 | 2011-10-27 | President And Fellows Of Harvard College | Methods and compositions for inhibition of beta2-adrenergic receptor degradation |
BR112012033060A2 (pt) | 2010-06-21 | 2018-02-27 | Mannkind Corp | métodos de sistema de liberação de fármaco em pó seco |
KR101940832B1 (ko) | 2011-04-01 | 2019-01-21 | 맨카인드 코포레이션 | 의약 카트리지용 블리스터 패키지 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
EP2776053A1 (en) | 2011-10-24 | 2014-09-17 | MannKind Corporation | Methods and compositions for treating pain |
SG11201500218VA (en) | 2012-07-12 | 2015-03-30 | Mannkind Corp | Dry powder drug delivery systems and methods |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
CN104069497A (zh) * | 2014-06-27 | 2014-10-01 | 东莞市凯法生物医药有限公司 | 一种降低药物耐受性的组合物、方法及其应用 |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
US20190070244A1 (en) * | 2017-06-30 | 2019-03-07 | The New Zealand Institute For Plant And Food Research Limited | Boysenberry compositions and methods of preparation and use thereof |
CA3070571A1 (en) | 2017-08-08 | 2019-02-14 | Odette M. Shaw | Boysenberry, apple, and blackcurrant compositions and methods of preparation and use therefor |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1195497B (it) | 1983-03-08 | 1988-10-19 | Opocrin Spa | Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina |
US4906476A (en) | 1988-12-14 | 1990-03-06 | Liposome Technology, Inc. | Novel liposome composition for sustained release of steroidal drugs in lungs |
US5380716A (en) | 1988-12-15 | 1995-01-10 | Glycomed, Inc. | Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation |
US5032679A (en) | 1988-12-15 | 1991-07-16 | Glycomed, Inc. | Heparin fragments as inhibitors of smooth muscle cell proliferation |
US5192548A (en) | 1990-04-30 | 1993-03-09 | Riker Laboratoires, Inc. | Device |
SE9302777D0 (sv) | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
US5874063A (en) | 1991-04-11 | 1999-02-23 | Astra Aktiebolag | Pharmaceutical formulation |
US5714376A (en) | 1991-10-23 | 1998-02-03 | Massachusetts Institute Of Technology | Heparinase gene from flavobacterium heparinum |
US5736124A (en) | 1991-12-12 | 1998-04-07 | Glaxo Group Limited | Aerosol formulations containing P134a and particulate medicament |
ES2079210T3 (es) | 1991-12-12 | 1996-01-01 | Glaxo Group Ltd | Formulacion farmaceutica de aerosol. |
SG48301A1 (en) * | 1991-12-18 | 1998-04-17 | Astra Ab | New combination |
US5690910A (en) * | 1995-08-18 | 1997-11-25 | Baker Norton Pharmaceuticals, Inc. | Method for treating asthma |
-
1999
- 1999-07-28 US US09/362,540 patent/US6235725B1/en not_active Expired - Lifetime
- 1999-10-13 CN CNB2004100629128A patent/CN100352448C/zh not_active Expired - Fee Related
- 1999-10-13 BR BR9915818-3A patent/BR9915818A/pt not_active Application Discontinuation
- 1999-10-13 HU HU0302492A patent/HUP0302492A3/hu not_active Application Discontinuation
- 1999-10-13 CZ CZ20011518A patent/CZ297914B6/cs not_active IP Right Cessation
- 1999-10-13 AU AU12051/00A patent/AU760119B2/en not_active Ceased
- 1999-10-13 SK SK590-2001A patent/SK285150B6/sk not_active IP Right Cessation
- 1999-10-13 JP JP2000579168A patent/JP4585121B2/ja not_active Expired - Fee Related
- 1999-10-13 EP EP99971300A patent/EP1124563B1/en not_active Expired - Lifetime
- 1999-10-13 WO PCT/US1999/024034 patent/WO2000025723A2/en active IP Right Grant
- 1999-10-13 CA CA2348926A patent/CA2348926C/en not_active Expired - Fee Related
- 1999-10-13 IL IL14286599A patent/IL142865A0/xx active IP Right Grant
- 1999-10-13 PL PL99364727A patent/PL195592B1/pl unknown
- 1999-10-13 CN CN99813923A patent/CN1329496A/zh active Pending
- 1999-10-13 AT AT99971300T patent/ATE277621T1/de active
- 1999-10-13 DE DE69920734T patent/DE69920734T2/de not_active Expired - Lifetime
- 1999-10-13 ES ES99971300T patent/ES2228173T3/es not_active Expired - Lifetime
- 1999-10-13 NZ NZ511399A patent/NZ511399A/en not_active IP Right Cessation
- 1999-10-13 PT PT99971300T patent/PT1124563E/pt unknown
- 1999-10-28 AR ARP990105443A patent/AR023911A1/es not_active Application Discontinuation
- 1999-10-29 CO CO99068642A patent/CO5160320A1/es unknown
- 1999-11-09 TW TW088118719A patent/TW565451B/zh not_active IP Right Cessation
-
2001
- 2001-04-27 NO NO20012097A patent/NO333194B1/no not_active IP Right Cessation
- 2001-04-27 IS IS5928A patent/IS2321B/is unknown
- 2001-04-30 IL IL142865A patent/IL142865A/en not_active IP Right Cessation
-
2002
- 2002-05-02 HK HK02103273.0A patent/HK1041596A1/zh unknown
-
2004
- 2004-12-06 CY CY20041101437T patent/CY1107493T1/el unknown
-
2011
- 2011-09-07 AR ARP110103258A patent/AR082913A2/es not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR023911A1 (es) | Composicion farmaceutica para tratar el asma y patologias relacionadas en un mamifero y uso de un broncodilatador y un efector para preparar la misma | |
James | Fractures of the proximal and middle phalanges of the fingers | |
AR030068A1 (es) | Composiciones farmaceuticas para el tratamiento de condiciones dolorosas, inflamatorias y ulcerosas de superficies epiteliales humedas como por ejemplo mucositis, estomatitis y sindrome de behcet | |
BR0111206A (pt) | Derivados de arilmetilamina para uso como inibidores de triptase | |
AR052221A1 (es) | Metodo para el tratamiento de la enfermedad poliquistosis renal | |
ES2235311T8 (es) | Formulación de budesónida/formoterol para inhalación que tiene una densidad aparente de vertido de 0,30 a 0,36 g/ml, un proceso para preparar la formulación y el uso de la misma. | |
BR9907270A (pt) | Composto, composição farmacêutica, uso de um composto, e, processos para tratamento ou profilaxia de doenças inflamatórias, por exemplo, asma ou copd, e para a preparação de um composto | |
ATE233084T1 (de) | Pharmazeutische aerosolformulierung | |
PT915910E (pt) | Analogos de exendina, processos para a sua preparacao e medicamentos que os contem | |
BR9714059A (pt) | S-omeprazol em uma forma neutra, processo para preparar o mesmo, uso deste, composição farmacêutica, e, processo para tratar uma condição relacionada com ácido gástrico. | |
BR9808641B1 (pt) | processo para preparação de uma forma de dosagem sólida, oral de rápida desintegração de uma substáncia farmaceuticamente ativa que possui um sabor inaceitável. | |
GB2385524A (en) | Compositions and methods of use for extracts of magnoliaceae | |
YU73600A (sh) | Novi nukleosidi koji imaju biciklične šećerne grupe | |
EA200200806A1 (ru) | Предупреждение потери и восстановление костной массы некоторыми агонистами простагландина | |
AR019681A1 (es) | Una formulacion conservante de amplio espectro, un metodo para preparar la formulacion conservante, una solucion de yodo propinilo estabilizadora y un procedimiento para destruir o retardar el crecimiento de procedimiento para destruir o retardar el crecimiento de microbios | |
BRPI0110947B8 (pt) | processo para a preparação de uma composição farmacêutica e composição farmacêutica assim obtida | |
ES512464A0 (es) | Un procedimiento para la preparacion de un nuevo antitrombosico a base de oligosacaridos y polisacaridos. | |
BR9005572A (pt) | Sulfonilaminocarboniltriazolinon as com substituintes ligados atraves do enxofre,processo para sua preparacao,composicoes herbicidas,aplicacao,processo para combater ervas daninhas,processo para a preparacao de composicoes herbicidas e derivados de triazolinona | |
ES2144404T3 (es) | Union de piezas huecas, asi como procedimiento para su fabricacion. | |
Fiaud | Theory and practice of vapour phase inhibitors | |
AR030047A1 (es) | Una composicion de poliisocianato liquida y un proceso para prepararla | |
BR9914815A (pt) | Composições para tratamento e prevenção de doenças cardiovasculares | |
NZ218175A (en) | Prazosin-pirbuterol combination for bronchodilation | |
RU2226103C2 (ru) | Способы и композиции для предотвращения развития толерантности к лекарственным средствам | |
KR910015697A (ko) | 한약재를 원료로한 보양주의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |