AR051662A1 - Proceso para l a preparacion de compuestos a base de quinolina y productos obtenidos de los mismos - Google Patents
Proceso para l a preparacion de compuestos a base de quinolina y productos obtenidos de los mismosInfo
- Publication number
- AR051662A1 AR051662A1 ARP050104640A ARP050104640A AR051662A1 AR 051662 A1 AR051662 A1 AR 051662A1 AR P050104640 A ARP050104640 A AR P050104640A AR P050104640 A ARP050104640 A AR P050104640A AR 051662 A1 AR051662 A1 AR 051662A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- formula
- reaction
- independently hydrogen
- carboalkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Child & Adolescent Psychology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Reivindicacion 1: Un método para preparar un compuesto de la formula (1), en la que: R1 es alquil, alcanoil, aroil, carboalcoxi o carboalcoxiaril; R2 y R3 son, independientemente, hidrogeno, hidroxi, alquil, alcoxi, halogeno, carboxamido, carboalcoxi, perfluoroalquil, ciano, alcanosulfonamido, alcanosulfonil, alcanamido, amino, alquilamino, dialquilamino, perfluoroalcoxi, alcanoiloxi, alcanoil, aroil, aril, arilalquil, heteroaril o heteroarilalquil; R6 y R7 son, independientemente, hidrogeno o alquil; n es 1 o 2; R4 y R5 son, independientemente, hidrogeno o alquil o se toman juntos con los carbonos a los que están unidos, forman un grupo cíclico que es cicloalquil, cicloalquenil, alquil con enlace de dos ciclos, alquenil con enlace de dos ciclos, piranil o tiopiranil en el que el átomo de sulfuro es opcionalmente oxidado para sulfoxida o sulfona; y la línea punteada representa un enlace doble opcional, que comprende la reaccion de un compuesto de la formula (1), en la que: n, R1, R2, R3, R6 y R7 son como se definio precedentemente, con un equivalente de formaldehído equivalente como mínimo y un reactivo con la formula R4-CH=CH-R5 o la formula R4-C:::C-R5, donde R4 y R5 son como se define aquí, en presencia de un ácido de Lewis y un solvente de reaccion para formar un componente de la formula (1), teniendo en cuenta que el equivalente del formaldehído está en forma de solido, al menos antes de la reaccion.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62530004P | 2004-11-05 | 2004-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR051662A1 true AR051662A1 (es) | 2007-01-31 |
Family
ID=35985415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050104640A AR051662A1 (es) | 2004-11-05 | 2005-11-04 | Proceso para l a preparacion de compuestos a base de quinolina y productos obtenidos de los mismos |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US7781427B2 (es) |
| EP (1) | EP1807428A2 (es) |
| JP (1) | JP2008519046A (es) |
| KR (1) | KR20070102665A (es) |
| CN (1) | CN101146809A (es) |
| AR (1) | AR051662A1 (es) |
| AU (1) | AU2005304915A1 (es) |
| CA (1) | CA2586623A1 (es) |
| CL (1) | CL2009001681A1 (es) |
| GT (1) | GT200500317A (es) |
| IL (1) | IL182996A0 (es) |
| NI (1) | NI200700118A (es) |
| NO (1) | NO20072473L (es) |
| PA (1) | PA8651801A1 (es) |
| RU (1) | RU2007117509A (es) |
| SG (1) | SG156695A1 (es) |
| TW (1) | TW200617011A (es) |
| WO (1) | WO2006052768A2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200500317A (es) * | 2004-11-05 | 2006-10-27 | Proceso para preparar compuestos de quinolina y productos obtenidos de los mismos | |
| AR054849A1 (es) * | 2005-07-26 | 2007-07-18 | Wyeth Corp | Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas |
| TW200734334A (en) * | 2006-01-13 | 2007-09-16 | Wyeth Corp | Treatment of substance abuse |
| EP1998781A2 (en) * | 2006-03-24 | 2008-12-10 | Wyeth a Corporation of the State of Delaware | Treatment of pain |
| AR060088A1 (es) * | 2006-03-24 | 2008-05-21 | Wyeth Corp | Metodos para tratar trastornos cognitivos y otros afines |
| CA2644662A1 (en) * | 2006-03-24 | 2007-10-04 | Wyeth | New therapeutic combinations for the treatment of depression |
| CL2008002777A1 (es) * | 2007-09-21 | 2010-01-22 | Wyeth Corp | Metodo de preparacion de compuestos diazepinoquinolinicos quirales por recristalizacion en un sistema de solvente ternario. |
| CA2784549C (en) * | 2009-12-18 | 2018-01-23 | Chevron Oronite Company Llc | Carbonyl-ene functionalized polyolefins |
| AU2019347545A1 (en) * | 2018-09-28 | 2021-03-11 | Celltrion, Inc. | Novel method for preparing (-)-cibenzoline succinate |
| WO2020067683A1 (en) * | 2018-09-28 | 2020-04-02 | Celltrion Inc. | Novel process for the preparation of (+)-cibenzoline succinate |
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| CL2008002777A1 (es) | 2007-09-21 | 2010-01-22 | Wyeth Corp | Metodo de preparacion de compuestos diazepinoquinolinicos quirales por recristalizacion en un sistema de solvente ternario. |
-
2005
- 2005-10-31 GT GT200500317A patent/GT200500317A/es unknown
- 2005-11-02 PA PA20058651801A patent/PA8651801A1/es unknown
- 2005-11-04 TW TW094138739A patent/TW200617011A/zh unknown
- 2005-11-04 JP JP2007540085A patent/JP2008519046A/ja not_active Withdrawn
- 2005-11-04 CN CNA2005800458254A patent/CN101146809A/zh active Pending
- 2005-11-04 US US11/267,448 patent/US7781427B2/en not_active Expired - Fee Related
- 2005-11-04 EP EP05817468A patent/EP1807428A2/en not_active Withdrawn
- 2005-11-04 KR KR1020077012744A patent/KR20070102665A/ko not_active Application Discontinuation
- 2005-11-04 AU AU2005304915A patent/AU2005304915A1/en not_active Abandoned
- 2005-11-04 CA CA002586623A patent/CA2586623A1/en not_active Abandoned
- 2005-11-04 AR ARP050104640A patent/AR051662A1/es unknown
- 2005-11-04 SG SG200907322-2A patent/SG156695A1/en unknown
- 2005-11-04 RU RU2007117509/04A patent/RU2007117509A/ru not_active Application Discontinuation
- 2005-11-04 WO PCT/US2005/040062 patent/WO2006052768A2/en active Application Filing
-
2007
- 2007-05-03 IL IL182996A patent/IL182996A0/en unknown
- 2007-05-04 NI NI200700118A patent/NI200700118A/es unknown
- 2007-05-16 NO NO20072473A patent/NO20072473L/no not_active Application Discontinuation
-
2009
- 2009-07-31 CL CL2009001681A patent/CL2009001681A1/es unknown
-
2010
- 2010-04-07 US US12/755,721 patent/US20100196714A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060122385A1 (en) | 2006-06-08 |
| WO2006052768A2 (en) | 2006-05-18 |
| CL2009001681A1 (es) | 2010-01-22 |
| PA8651801A1 (es) | 2006-07-03 |
| US20100196714A1 (en) | 2010-08-05 |
| US7781427B2 (en) | 2010-08-24 |
| AU2005304915A1 (en) | 2006-05-18 |
| NO20072473L (no) | 2007-07-24 |
| GT200500317A (es) | 2006-10-27 |
| IL182996A0 (en) | 2007-08-19 |
| TW200617011A (en) | 2006-06-01 |
| CA2586623A1 (en) | 2006-05-18 |
| RU2007117509A (ru) | 2008-12-10 |
| JP2008519046A (ja) | 2008-06-05 |
| KR20070102665A (ko) | 2007-10-19 |
| EP1807428A2 (en) | 2007-07-18 |
| CN101146809A (zh) | 2008-03-19 |
| WO2006052768A3 (en) | 2006-08-17 |
| NI200700118A (es) | 2008-05-09 |
| SG156695A1 (en) | 2009-11-26 |
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