AR049346A1 - 3-amino-1-arilpropil-indoles como inhibidores de reabsorcion de monoaminas - Google Patents
3-amino-1-arilpropil-indoles como inhibidores de reabsorcion de monoaminasInfo
- Publication number
- AR049346A1 AR049346A1 ARP050102217A ARP050102217A AR049346A1 AR 049346 A1 AR049346 A1 AR 049346A1 AR P050102217 A ARP050102217 A AR P050102217A AR P050102217 A ARP050102217 A AR P050102217A AR 049346 A1 AR049346 A1 AR 049346A1
- Authority
- AR
- Argentina
- Prior art keywords
- phenyl
- indole
- optionally substituted
- reabsortion
- arilpropil
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Abstract
Composiciones farmacéuticas que los contienen y métodos para el uso de los mismos en la fabricacion de medicamentos destinados al tratamiento de la depresion o ansiedad. Reivindicacion 1: Un compuesto de formula (1) o sus sales, solvatos o profármacos farmacéuticamente aceptables, en donde Ar es indolilo; indazolilo; bencimidazolilo; benzofuranilo; benzotiofuranilo; benzoxazolilo; o benzotiazolilo; cada uno opcionalmente sustituido; R1 es: arilo elegido entre fenilo y naftilo; heteroarilo elegido entre tienilo, furanilo, piridinilo, pirimidinilo, quinolinilo e isoquinolinilo; cicloalquilo; o alquilo ramificado C4-7; cada uno opcionalmente sustituido; y R2 y R3 cada uno independientemente es hidrogeno, alquilo, hidroxialquilo o alcoxialquilo, o R2 y R3 junto con el nitrogeno al que están unidos pueden formar un anillo de cuatro a siete miembros que incluye opcionalmente un heteroátomo adicional elegido entre N, O y S; con la condicion de que cuando Ar es indol-1-ilo y R1 es fenilo, entonces R2 y R3 no son simultáneamente metilo y no forman un anillo hexagonal, y además con la condicion de que cuando Ar es indol-3-ilo y R1 es fenilo o 3-metoxifenilo, entonces R2 y R3 no son simultáneamente hidrogeno.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57604404P | 2004-06-01 | 2004-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR049346A1 true AR049346A1 (es) | 2006-07-19 |
Family
ID=35094091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050102217A AR049346A1 (es) | 2004-06-01 | 2005-05-30 | 3-amino-1-arilpropil-indoles como inhibidores de reabsorcion de monoaminas |
Country Status (19)
Country | Link |
---|---|
US (1) | US7863305B2 (es) |
EP (1) | EP1756054B1 (es) |
JP (1) | JP4698671B2 (es) |
CN (1) | CN1993321A (es) |
AR (1) | AR049346A1 (es) |
AT (1) | ATE462692T1 (es) |
AU (1) | AU2005250116B2 (es) |
BR (1) | BRPI0511722A (es) |
CA (1) | CA2569238A1 (es) |
DE (1) | DE602005020280D1 (es) |
ES (1) | ES2340180T3 (es) |
IL (1) | IL179371A (es) |
MX (1) | MXPA06014018A (es) |
NO (1) | NO20065880L (es) |
NZ (1) | NZ551292A (es) |
RU (1) | RU2382031C2 (es) |
TW (1) | TWI306027B (es) |
WO (1) | WO2005118539A1 (es) |
ZA (1) | ZA200609545B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4698671B2 (ja) | 2004-06-01 | 2011-06-08 | エフ.ホフマン−ラ ロシュ アーゲー | モノアミン再取り込み阻害剤としての3−アミノ−1−アリールプロピルインドール |
TW200800888A (en) | 2005-09-29 | 2008-01-01 | Wyeth Corp | Substituted propylamine derivatives and methods of their use |
US20070072897A1 (en) * | 2005-09-29 | 2007-03-29 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
EP1957488B1 (en) * | 2005-11-30 | 2009-09-09 | F.Hoffmann-La Roche Ag | 3-amino-2-arylpropyl azaindoles and uses thereof |
EP1957454B1 (en) * | 2005-11-30 | 2011-07-20 | F. Hoffmann-La Roche AG | Methods for synthesis of 3-amino-1-arylpropyl indoles |
CN101316818B (zh) * | 2005-11-30 | 2011-08-31 | 弗·哈夫曼-拉罗切有限公司 | 3-氨基-1-芳基丙基吲哚类和氮杂取代的吲哚类 |
WO2009045700A2 (en) * | 2007-10-05 | 2009-04-09 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (flap) inhibitors |
US8101642B2 (en) | 2008-06-05 | 2012-01-24 | Sk Biopharmaceuticals Co., Ltd. | 3-substituted propanamine compounds |
KR101603487B1 (ko) * | 2008-06-05 | 2016-03-17 | 에스케이바이오팜 주식회사 | 3-치환된 프로판아민 화합물 |
US8546576B2 (en) * | 2008-06-06 | 2013-10-01 | Sk Biopharmaceuticals Co., Ltd. | 3 or 4-substituted piperidine compounds |
DE102008030206A1 (de) | 2008-06-25 | 2009-12-31 | Bayer Schering Pharma Aktiengesellschaft | 3-Cyanoalky- und 3-Hydroxyalkyl-Indole und ihre Verwendung |
DE102008030207A1 (de) | 2008-06-25 | 2009-12-31 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 7-Sulfanylmethyl-, 7-Sulfinylmethyl- und 7-Sulfonylmethyl-Indole und ihre Verwendung |
WO2012097744A1 (en) | 2011-01-20 | 2012-07-26 | Merck Sharp & Dohme Corp. | Mineralocorticoid receptor antagonists |
LT2875013T (lt) * | 2012-07-17 | 2018-02-26 | Glaxosmithkline Intellectual Property (No. 2) Limited | Indolkarbonitrilai, kaip selektyvūs androgeno receptoriaus moduliatoriai |
NZ707366A (en) | 2012-11-07 | 2018-11-30 | Karus Therapeutics Ltd | Novel histone deacetylase inhibitors and their use in therapy |
DK2994465T3 (en) | 2013-05-10 | 2018-10-08 | Karus Therapeutics Ltd | HISTONDEACETYLASE INHIBITORS UNKNOWN |
GB201419264D0 (en) | 2014-10-29 | 2014-12-10 | Karus Therapeutics Ltd | Compounds |
GB201419228D0 (en) | 2014-10-29 | 2014-12-10 | Karus Therapeutics Ltd | Compounds |
AR112463A1 (es) * | 2017-07-27 | 2019-10-30 | Esteve Pharmaceuticals Sa | Derivados de propanamina para tratar el dolor y estados relacionados con dolor |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB705652A (en) * | 1948-10-01 | 1954-03-17 | Farbewerke Hoechst Ag | Manufacture of 3-aminopropane compounds |
DE849108C (de) | 1948-10-01 | 1952-09-11 | Hoechst Ag | Verfahren zur Herstellung von 1-disubstituierten 3-Aminopropanen |
NL82464C (es) * | 1952-01-05 | |||
US2708197A (en) * | 1952-05-24 | 1955-05-10 | Upjohn Co | Preparation of (hydroxy-3-indole)-alkylamines |
US2984670A (en) | 1959-05-22 | 1961-05-16 | Upjohn Co | Novel 3-(1-hydroxy-1-phenyl-3-aminopropyl) indoles |
GB992731A (en) | 1962-09-28 | 1965-05-19 | Koninklijke Pharma Fab Nv | Aminoalkyl-indolyl-benzyl alcohols |
US3972935A (en) * | 1974-07-03 | 1976-08-03 | Eli Lilly And Company | Antiarrhythmic agents |
JPH0314562A (ja) * | 1988-04-11 | 1991-01-23 | Nippon Chemiphar Co Ltd | 新規なアルキレンジアミン誘導体およびグルタミン酸遮断剤 |
DK344489D0 (da) * | 1989-07-12 | 1989-07-12 | Novo Nordisk As | Substituerede 2-imidazoliner og fremstilling og anvendelse deraf |
US5561163A (en) | 1990-08-31 | 1996-10-01 | Deprenyl Animal Health, Inc. | Treating hearing loss with deprenyl |
JPH0578315A (ja) * | 1991-03-11 | 1993-03-30 | Kyowa Hakko Kogyo Co Ltd | インドール誘導体 |
US5177088A (en) | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
US5185350A (en) | 1991-09-23 | 1993-02-09 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted pyridinylamino-1h-indoles,1h-indazoles,2h-indazoles, benzo (b)thiophenes and 1,2-benzisothiazoles |
EP0600830A1 (de) | 1992-11-27 | 1994-06-08 | Ciba-Geigy Ag | Substituierte Derivate von Diaminophthalimid als Protein-Tyrosin-Kinase-Hemmer |
GB9225141D0 (en) | 1992-12-01 | 1993-01-20 | Smithkline Beecham Corp | Chemical compounds |
FR2705095B1 (fr) * | 1993-05-12 | 1995-06-23 | Adir | Nouveaux indoles substitués, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
GB9518552D0 (en) | 1995-09-11 | 1995-11-08 | Fujisawa Pharmaceutical Co | New heterocyclic compounds |
GB9523948D0 (en) * | 1995-11-23 | 1996-01-24 | Univ East Anglia | Process for preparing n-benzyl indoles |
EP0912494A1 (en) | 1996-06-07 | 1999-05-06 | Nps Pharmaceuticals, Inc. | Coumpounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
IT1286866B1 (it) * | 1996-10-28 | 1998-07-17 | Menarini Farma Ind | Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi |
SE9701144D0 (sv) | 1997-03-27 | 1997-03-27 | Pharmacia & Upjohn Ab | Novel compounds, their use and preparation |
EP0887348A1 (en) | 1997-06-25 | 1998-12-30 | Boehringer Mannheim Italia S.p.A. | Bis-Indole derivatives having antimetastatic activity, a process for their preparation and pharmaceutical compositions containing them |
EP1017682A4 (en) | 1997-09-26 | 2000-11-08 | Merck & Co Inc | NEW ANGIOGENESIS INHIBITORS |
AU1124399A (en) | 1997-10-28 | 1999-05-17 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
AU1197299A (en) | 1997-10-28 | 1999-05-17 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
AU771252B2 (en) | 1998-07-13 | 2004-03-18 | Nps Pharmaceuticals, Inc. | Methods and compounds for treating depression and other disorders |
SE9903998D0 (sv) | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
FR2814073B1 (fr) | 2000-09-21 | 2005-06-24 | Yang Ji Chemical Company Ltd | Composition pharmaceutique antifongique et/ou antiparasitaire et nouveaux derives de l'indole a titre de principes actifs d'une telle composition |
WO2002069965A1 (en) | 2001-03-05 | 2002-09-12 | Transtech Pharma, Inc. | Benzimidazole derivatives as therapeutic agents |
AU2003227521A1 (en) * | 2002-05-30 | 2003-12-19 | Neurosearch A/S | Combination of atypical antipsychotic and serotonin reuptake inhibitor for the treatment of chronic pain |
GB0223915D0 (en) * | 2002-10-15 | 2002-11-20 | Univ Cardiff | Benzofuran derivatives formulations and uses thereof |
US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
US7414052B2 (en) * | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US7517899B2 (en) * | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
JP4698671B2 (ja) | 2004-06-01 | 2011-06-08 | エフ.ホフマン−ラ ロシュ アーゲー | モノアミン再取り込み阻害剤としての3−アミノ−1−アリールプロピルインドール |
-
2005
- 2005-05-27 JP JP2007513816A patent/JP4698671B2/ja not_active Expired - Fee Related
- 2005-05-27 WO PCT/EP2005/005734 patent/WO2005118539A1/en active Application Filing
- 2005-05-27 AT AT05747507T patent/ATE462692T1/de active
- 2005-05-27 CN CNA2005800260760A patent/CN1993321A/zh active Pending
- 2005-05-27 DE DE602005020280T patent/DE602005020280D1/de active Active
- 2005-05-27 EP EP05747507A patent/EP1756054B1/en active Active
- 2005-05-27 ES ES05747507T patent/ES2340180T3/es active Active
- 2005-05-27 MX MXPA06014018A patent/MXPA06014018A/es active IP Right Grant
- 2005-05-27 RU RU2006142346/04A patent/RU2382031C2/ru not_active IP Right Cessation
- 2005-05-27 NZ NZ551292A patent/NZ551292A/en unknown
- 2005-05-27 CA CA002569238A patent/CA2569238A1/en not_active Abandoned
- 2005-05-27 AU AU2005250116A patent/AU2005250116B2/en not_active Ceased
- 2005-05-27 BR BRPI0511722-4A patent/BRPI0511722A/pt not_active IP Right Cessation
- 2005-05-30 AR ARP050102217A patent/AR049346A1/es unknown
- 2005-05-30 TW TW094117705A patent/TWI306027B/zh active
- 2005-06-01 US US11/142,076 patent/US7863305B2/en not_active Expired - Fee Related
-
2006
- 2006-11-16 IL IL179371A patent/IL179371A/en not_active IP Right Cessation
- 2006-11-16 ZA ZA200609545A patent/ZA200609545B/en unknown
- 2006-12-19 NO NO20065880A patent/NO20065880L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2005250116A1 (en) | 2005-12-15 |
MXPA06014018A (es) | 2007-02-08 |
ES2340180T3 (es) | 2010-05-31 |
TWI306027B (en) | 2009-02-11 |
BRPI0511722A (pt) | 2008-01-08 |
RU2382031C2 (ru) | 2010-02-20 |
JP2008500983A (ja) | 2008-01-17 |
US20060025467A1 (en) | 2006-02-02 |
ATE462692T1 (de) | 2010-04-15 |
AU2005250116B2 (en) | 2011-01-20 |
RU2006142346A (ru) | 2008-07-20 |
NZ551292A (en) | 2009-11-27 |
CA2569238A1 (en) | 2005-12-15 |
DE602005020280D1 (de) | 2010-05-12 |
EP1756054B1 (en) | 2010-03-31 |
CN1993321A (zh) | 2007-07-04 |
WO2005118539A1 (en) | 2005-12-15 |
IL179371A (en) | 2012-07-31 |
NO20065880L (no) | 2006-12-20 |
JP4698671B2 (ja) | 2011-06-08 |
EP1756054A1 (en) | 2007-02-28 |
US7863305B2 (en) | 2011-01-04 |
IL179371A0 (en) | 2007-03-08 |
ZA200609545B (en) | 2008-06-25 |
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