AR044940A1 - Compuestos heterociclicos y su uso como moduladores de gamma opioides - Google Patents
Compuestos heterociclicos y su uso como moduladores de gamma opioidesInfo
- Publication number
- AR044940A1 AR044940A1 ARP040102271A ARP040102271A AR044940A1 AR 044940 A1 AR044940 A1 AR 044940A1 AR P040102271 A ARP040102271 A AR P040102271A AR P040102271 A ARP040102271 A AR P040102271A AR 044940 A1 AR044940 A1 AR 044940A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkanyl
- quinolinyl
- amino
- group
- alkenyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Addiction (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente se refiere a moduladores de receptores de delta opioides. En forma más específica, la presente se refiere a moduladores tricíclicos de delta-opioides. Se describen, además, composiciones de uso farmacéutico y veterinario y métodos de tratamiento del dolor leve a moderadamente grave y varias enfermedades que usan los compuestos de la presente. Reivindicación 1: Un compuesto de fórmula (1) en donde R1 y R2 son sustituyentes seleccionados en forma independiente del grupo formado por H y alcanilo C1-8; R3 se selecciona del grupo formado por H, alcanilo C1-8, halo 1-3alcanilo(C1-3), alquenilo C2-8, alquinilo C2-8, cicloalcanilo C3-8, cicloalcanil alcanilo (C1-8), alcanil C1-8 oxialcanilo (C1-8), alcaniltio C1-8 alcanilo(C1-8), hidroxialcanilo C1-8, alcaniloxicarbonilo C1-3, halo1-3 alcanil(C1-8) carbonilo, formilo, tioformilo, carbamimidoilo, fenilimino alcanilo (C1-8), fenilalcanilo (C1-8), fenilalquenilo (C1-8),fenilalquinilo (C1-8), naftilalcanilo C1-8 y heteoarilalcanilo (C1-8), donde el fenilo, naftilo y heteroarilo están sustituidos en forma opcional con 1 a 3 sustituyentes seleccionados en forma independiente del grupo formado por alcanilo C1-8, alquenilo C2-6, alcaniloxi C1-6, amino, alcanilamino C1-6, di(alcanil C1-6)amino, alcanil C1-6carbonilo, alcanil C1-6carboniloxi, alcanil C1-6carbonilamino, alcanil C1-6tio, alcanil C1-6sulfonilo, halógeno, hidroxi, ciano, fluoroalcanilo, tioureido, y fluoroalcaniloxi; en forma alternativa, cuando el fenilo y el heteroarilo están sustituidos en forma opcional con dos sustituyentes unidos a átomos de C adyacentes, los dos sustituyentes pueden formar, juntos, un único resto fusionado; donde el resto fusionado se selecciona del grupo formado por -(CH2)3-6- y -O(CH2)1-3O-; R4 es de 1 a 3 sustituyentes seleccionados en forma independiente del grupo formado por H, alcanilo C1-6, alquenilo C2-6, alcaniloxi C1-6, amino, alcanilamino C1-6, di(alcanil C1-6)amino, alcanil C1-6carbonilo, alcanil C1-6carboniloxi, alcanil C1-6oxicarbonilo, alcanil C1-6aminocarbonilo, di(alcanil C1-6)aminocarbonilo, alcanil C1-6carbonilamino, alcanil C1-6tio, alcanil C1-6sulfonilo, halógeno, hidroxi, ciano, hidroxicarbonilo, arilo C6-10, cromanilo, cromenilo, furanilo, imidazolilo, indazolilo, indolilo, indolinilo, isoindolinilo, isoquinolinilo, isotiazolilo, isoxazolilo, naftiridinilo, oxazolilo, pirazinilo, pirazolilo, piridazinilo, piridinilo, pirimidinilo, pirrolilo, quinazolinilo, quinolinilo, quinolizinilo, quinoxalinilo, tetrazolilo, tiazolilo, tiofenilo, fluoroalcanilo y fluoroalcaniloxi; o en forma opcional, cuando R4 es dos sustituyentes unidos a átomos de C adyacentes, los dos sustituyentes juntos forman un único resto fusionado; en el cual el resto fusionado se selecciona del grupo formado por -(CH2)3-5- y -O(CH2)1-2O-; R5 es de 1 a 2 sustituyentes seleccionados en forma independiente del grupo formado por H, alcanilo C1-6, alquenilo C2-6, alcanil C1-6oxi, amino, alcanil C1-6amino, di(alcanil C1-6)amino, alcanil C1-6carbonilo, alcanil C1-6carboniloxi, alcanil C1-6oxicarbonilo, alcanil C1-6aminocarbonilo, alcanil C1-6carbonilamino, alcanil C1-6tio, alcanil C1-6sulfonilo, halógeno, hidroxi, ciano, fluoroalcanilo y fluoroalcaniloxi; A es -(CH2)m, en el cual m es 0, 2 o 3; Y es -(CH2)nX- o -X(CH2)n; X es O ,o S, n es 0 o 1; Z es O o S; y sus enantiómeros, diastereómeros, tautómeros, solvatos o sales aceptables desde el punto de vista farmacéutico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48338903P | 2003-06-27 | 2003-06-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR044940A1 true AR044940A1 (es) | 2005-10-12 |
Family
ID=33563931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040102271A AR044940A1 (es) | 2003-06-27 | 2004-06-28 | Compuestos heterociclicos y su uso como moduladores de gamma opioides |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US7589103B2 (es) |
| EP (1) | EP1644373A1 (es) |
| JP (1) | JP4810423B2 (es) |
| KR (1) | KR101132208B1 (es) |
| CN (1) | CN100513407C (es) |
| AR (1) | AR044940A1 (es) |
| AU (1) | AU2004253898A1 (es) |
| BR (1) | BRPI0411998A (es) |
| CA (1) | CA2530444C (es) |
| CR (1) | CR8166A (es) |
| EA (1) | EA015491B1 (es) |
| EC (1) | ECSP056256A (es) |
| HK (1) | HK1097532A1 (es) |
| IL (1) | IL172713A0 (es) |
| NO (1) | NO333611B1 (es) |
| NZ (1) | NZ572901A (es) |
| TW (1) | TWI368510B (es) |
| UA (1) | UA86024C2 (es) |
| WO (1) | WO2005003131A1 (es) |
| ZA (1) | ZA200600770B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0300105D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof |
| SE0300103D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| BRPI0411998A (pt) | 2003-06-27 | 2006-09-05 | Janssen Pharmaceutica Nv | moduladores delta-opióides tricìclicos |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| BRPI0511834A (pt) | 2004-07-14 | 2008-01-08 | Ptc Therapeutics Inc | métodos por tratar hepatite c |
| US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| NZ553329A (en) | 2004-07-22 | 2010-09-30 | Ptc Therapeutics Inc | Thienopyridines for treating hepatitis C |
| WO2007030089A1 (en) * | 2004-08-05 | 2007-03-15 | Janssen Pharmaceutica N.V. | Tricyclic delta- opioid modulators |
| US7439239B2 (en) * | 2004-12-22 | 2008-10-21 | Janssen Pharmaceutica N.V. | Tricyclic δ- opioid modulators |
| BRPI0519201A2 (pt) * | 2004-12-22 | 2008-12-30 | Janssen Pharmaceutica Nv | moduladores de delta-opiàide tricÍclico |
| WO2006069275A1 (en) * | 2004-12-22 | 2006-06-29 | Janssen Pharmaceutica N.V. | Tricyclic delta-opioid modulators |
| CN101128460A (zh) * | 2005-01-06 | 2008-02-20 | 詹森药业有限公司 | 三环的δ-阿片样物质调节剂 |
| US7935821B2 (en) * | 2005-06-09 | 2011-05-03 | Mallinckrodt Inc. | Method for separation and purification of naltrexone by preparative chromatography |
| WO2006138528A2 (en) * | 2005-06-16 | 2006-12-28 | Janssen Pharmaceutica N.V | Tricyclic opioid modulators |
| CN101522665B (zh) | 2006-09-29 | 2012-02-08 | 日本脏器制药株式会社 | *庚英衍生物 |
| WO2008096360A2 (en) | 2007-02-06 | 2008-08-14 | Technion Research & Development Foundation Ltd. | Frictionless molecular rotary motors |
| AU2008349239B2 (en) | 2008-01-30 | 2012-12-06 | Nippon Zoki Pharmaceutical Co., Ltd. | Piperidine derivative |
| EP2319840B1 (en) | 2008-08-01 | 2015-12-16 | Nippon Zoki Pharmaceutical Co., Ltd. | Aminopropylidene derivative |
| IT1402691B1 (it) * | 2010-11-10 | 2013-09-13 | Lamberti Spa | Tioxantoni a bassa migrabilita' |
| WO2018083635A2 (en) | 2016-11-04 | 2018-05-11 | Auckland Uniservices Limited | Tricyclic heterocyclic derivatives and uses thereof |
| CN110234634A (zh) * | 2016-12-28 | 2019-09-13 | 汉高股份有限及两合公司 | 噻吨酮衍生物光引发剂 |
| CN110483871A (zh) * | 2019-08-15 | 2019-11-22 | 陈全明 | 一种抗压耐磨的hdpe双壁波纹管 |
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| WO2002048122A2 (en) | 2000-12-14 | 2002-06-20 | Ortho-Mcneil Pharmaceutical, Inc. | Benzamidine derivatives |
| SE0101765D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
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| EP1321169A1 (en) * | 2001-12-18 | 2003-06-25 | Biofrontera Pharmaceuticals AG | Combination of a serotonin receptor antagonist with a histidine decarboxylase inhibitor as a medicament |
| BR0314108A (pt) | 2002-09-18 | 2006-04-25 | Fmc Corp | derivados tricìclios inseticidas |
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| WO2007030089A1 (en) * | 2004-08-05 | 2007-03-15 | Janssen Pharmaceutica N.V. | Tricyclic delta- opioid modulators |
| BRPI0519201A2 (pt) * | 2004-12-22 | 2008-12-30 | Janssen Pharmaceutica Nv | moduladores de delta-opiàide tricÍclico |
| US7439239B2 (en) | 2004-12-22 | 2008-10-21 | Janssen Pharmaceutica N.V. | Tricyclic δ- opioid modulators |
| WO2006069275A1 (en) * | 2004-12-22 | 2006-06-29 | Janssen Pharmaceutica N.V. | Tricyclic delta-opioid modulators |
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-
2004
- 2004-06-22 BR BRPI0411998-3A patent/BRPI0411998A/pt not_active IP Right Cessation
- 2004-06-22 CN CNB2004800237098A patent/CN100513407C/zh not_active Expired - Fee Related
- 2004-06-22 UA UAA200512736A patent/UA86024C2/ru unknown
- 2004-06-22 US US10/873,527 patent/US7589103B2/en active Active
- 2004-06-22 KR KR1020057025145A patent/KR101132208B1/ko not_active IP Right Cessation
- 2004-06-22 WO PCT/US2004/019911 patent/WO2005003131A1/en active Application Filing
- 2004-06-22 EA EA200501868A patent/EA015491B1/ru not_active IP Right Cessation
- 2004-06-22 NZ NZ572901A patent/NZ572901A/en unknown
- 2004-06-22 CA CA2530444A patent/CA2530444C/en not_active Expired - Fee Related
- 2004-06-22 JP JP2006517517A patent/JP4810423B2/ja not_active Expired - Fee Related
- 2004-06-22 AU AU2004253898A patent/AU2004253898A1/en not_active Abandoned
- 2004-06-22 EP EP04755822A patent/EP1644373A1/en not_active Withdrawn
- 2004-06-28 AR ARP040102271A patent/AR044940A1/es not_active Application Discontinuation
- 2004-06-28 TW TW093118831A patent/TWI368510B/zh not_active IP Right Cessation
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2005
- 2005-12-20 IL IL172713A patent/IL172713A0/en unknown
- 2005-12-27 EC EC2005006256A patent/ECSP056256A/es unknown
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2006
- 2006-01-02 CR CR8166A patent/CR8166A/es not_active Application Discontinuation
- 2006-01-26 ZA ZA200600770A patent/ZA200600770B/en unknown
- 2006-01-27 NO NO20060446A patent/NO333611B1/no not_active IP Right Cessation
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2007
- 2007-03-23 HK HK07103171.8A patent/HK1097532A1/xx not_active IP Right Cessation
-
2009
- 2009-08-06 US US12/536,635 patent/US7982042B2/en not_active Expired - Fee Related
-
2011
- 2011-06-10 US US13/157,846 patent/US8106207B2/en not_active Expired - Fee Related
- 2011-12-22 US US13/334,374 patent/US8350041B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060035645A (ko) | 2006-04-26 |
| EA015491B1 (ru) | 2011-08-30 |
| HK1097532A1 (en) | 2007-06-29 |
| EP1644373A1 (en) | 2006-04-12 |
| IL172713A0 (en) | 2006-04-10 |
| CN1839135A (zh) | 2006-09-27 |
| UA86024C2 (ru) | 2009-03-25 |
| AU2004253898A1 (en) | 2005-01-13 |
| CA2530444A1 (en) | 2005-01-13 |
| KR101132208B1 (ko) | 2012-04-12 |
| US20050009860A1 (en) | 2005-01-13 |
| WO2005003131A1 (en) | 2005-01-13 |
| NO333611B1 (no) | 2013-07-22 |
| US8106207B2 (en) | 2012-01-31 |
| BRPI0411998A (pt) | 2006-09-05 |
| US20090298867A1 (en) | 2009-12-03 |
| JP4810423B2 (ja) | 2011-11-09 |
| JP2007516175A (ja) | 2007-06-21 |
| CR8166A (es) | 2009-01-16 |
| TWI368510B (en) | 2012-07-21 |
| CN100513407C (zh) | 2009-07-15 |
| CA2530444C (en) | 2012-03-13 |
| EA200501868A1 (ru) | 2006-06-30 |
| US20120095010A1 (en) | 2012-04-19 |
| ZA200600770B (en) | 2007-05-30 |
| NZ572901A (en) | 2010-06-25 |
| US7589103B2 (en) | 2009-09-15 |
| US8350041B2 (en) | 2013-01-08 |
| US7982042B2 (en) | 2011-07-19 |
| US20110245291A1 (en) | 2011-10-06 |
| NO20060446L (no) | 2006-03-27 |
| ECSP056256A (es) | 2006-04-19 |
| TW200528105A (en) | 2005-09-01 |
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