AR037047A1 - Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales - Google Patents

Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales

Info

Publication number
AR037047A1
AR037047A1 ARP020104078A ARP020104078A AR037047A1 AR 037047 A1 AR037047 A1 AR 037047A1 AR P020104078 A ARP020104078 A AR P020104078A AR P020104078 A ARP020104078 A AR P020104078A AR 037047 A1 AR037047 A1 AR 037047A1
Authority
AR
Argentina
Prior art keywords
prevention
treatment
peroxide
vaginal
peroxide concentration
Prior art date
Application number
ARP020104078A
Other languages
English (en)
Inventor
William J Bologna
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Publication of AR037047A1 publication Critical patent/AR037047A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composición farmacéutica vaginal de aplicación local en forma de gel, crema, pastilla, supositorio y otras adecuadas, con una mezcla sinérgica de a)0,01% a 15% en peso de fuente de peróxido como ser peróxido de carbamida, peróxido de alquilo o bencilo y otros complejos de H202 y b) polímero bioadhesivo policarboxílico que se hincha en agua pero que es insoluble, como ser policarbofilo. Puede contener aditivos como lubricantes, conservantes, colorantes y otros y agua como vehículo. Es de liberación prolongada durante al menos 12 a 72 horas, aumenta la concentración de oxígeno y disminuye el ph en la vagina, sin esterilización ni eliminación de flora normal. Se usa para un método de tratamiento o prevención de infecciones vaginales, tal como vaginosis bacteriana, sin causar inflamación pélvica.
ARP020104078A 2001-10-29 2002-10-28 Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales AR037047A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33068301P 2001-10-29 2001-10-29
US10/278,910 US7709026B2 (en) 2001-10-29 2002-10-24 Low concentration of peroxide for treating or preventing vaginal infections

Publications (1)

Publication Number Publication Date
AR037047A1 true AR037047A1 (es) 2004-10-20

Family

ID=26959335

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020104078A AR037047A1 (es) 2001-10-29 2002-10-28 Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales

Country Status (31)

Country Link
US (1) US7709026B2 (es)
EP (1) EP1441769B1 (es)
JP (2) JP5153049B2 (es)
KR (1) KR101009146B1 (es)
CN (1) CN1578676A (es)
AR (1) AR037047A1 (es)
AT (1) ATE297222T1 (es)
AU (1) AU2002346897B2 (es)
BR (1) BR0213584A (es)
CA (1) CA2465133C (es)
DE (1) DE60204584T2 (es)
DK (1) DK1441769T3 (es)
ES (1) ES2243772T3 (es)
HK (1) HK1063290A1 (es)
HR (1) HRP20040480B1 (es)
HU (1) HU229487B1 (es)
IL (2) IL161512A0 (es)
MA (1) MA26289A1 (es)
ME (1) MEP34608A (es)
MX (1) MXPA04003977A (es)
MY (1) MY137791A (es)
NO (1) NO20042199L (es)
NZ (1) NZ532294A (es)
PE (1) PE20030492A1 (es)
PL (2) PL216746B1 (es)
PT (1) PT1441769E (es)
RS (1) RS51154B (es)
RU (1) RU2329829C2 (es)
SI (1) SI1441769T1 (es)
WO (1) WO2003037382A1 (es)
ZA (1) ZA200402943B (es)

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DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
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US20050276865A1 (en) * 2004-05-20 2005-12-15 Servet Buyuktimkin Peroxide compounds for the prevention and treatment of sexual dysfunction in humans
DE102004054552A1 (de) * 2004-11-11 2006-05-18 Hcb Happy Child Birth Holding Ag Neue Zusammensetzung zur Erleichterung der Humangeburt
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US20120074014A1 (en) * 2010-09-27 2012-03-29 Lutran Industries, Inc. Product typically based on salt of peroxymonosulfuric acid and suitable for medicinal usage, and associated product fabrication
US10383894B2 (en) * 2010-03-17 2019-08-20 Lutran Industries, Inc. Human medicinal treatment using salt of peroxymonosulfuric acid
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US9895311B2 (en) 2014-09-25 2018-02-20 Pharmiva Ab Foam-forming compositions and methods for delivering an active to a body cavity
EP3606516A4 (en) * 2017-03-30 2021-01-20 Scientelle, LLC METHODS OF TREATMENT AND PREVENTION OF INFECTION
ES2947949T3 (es) 2017-05-23 2023-08-24 Pharmiva Ab Composiciones formadoras de espuma para administrar un activo a una cavidad corporal
CN113164384A (zh) * 2018-10-26 2021-07-23 维拉莫有限公司 黏膜粘附性凝胶组合物
US11850303B2 (en) * 2020-10-27 2023-12-26 Uqora, Inc. Gel and a suppository and methods to provide the gel and suppository

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Also Published As

Publication number Publication date
JP2005510505A (ja) 2005-04-21
PE20030492A1 (es) 2003-06-16
BR0213584A (pt) 2004-08-24
ZA200402943B (en) 2005-03-30
JP2010248232A (ja) 2010-11-04
US20030091644A1 (en) 2003-05-15
DK1441769T3 (da) 2005-09-12
ES2243772T3 (es) 2005-12-01
MEP34608A (en) 2011-02-10
EP1441769B1 (en) 2005-06-08
PL216746B1 (pl) 2014-05-30
AU2002346897B2 (en) 2008-04-17
MXPA04003977A (es) 2004-07-08
MY137791A (en) 2009-03-31
IL161512A (en) 2009-07-20
RU2004116312A (ru) 2005-04-10
MA26289A1 (fr) 2004-09-01
CN1578676A (zh) 2005-02-09
US7709026B2 (en) 2010-05-04
CA2465133C (en) 2012-03-06
CA2465133A1 (en) 2003-05-08
PT1441769E (pt) 2005-08-31
HRP20040480B1 (en) 2007-11-30
EP1441769A1 (en) 2004-08-04
RS51154B (sr) 2010-10-31
RU2329829C2 (ru) 2008-07-27
HU229487B1 (en) 2014-01-28
NO20042199L (no) 2004-05-26
NZ532294A (en) 2006-12-22
JP5153049B2 (ja) 2013-02-27
HRP20040480A2 (en) 2004-10-31
RS36604A (en) 2006-12-15
PL369725A1 (en) 2005-05-02
HUP0401672A3 (en) 2008-04-28
IL161512A0 (en) 2004-09-27
HK1063290A1 (en) 2004-12-24
ATE297222T1 (de) 2005-06-15
SI1441769T1 (sl) 2005-12-31
KR101009146B1 (ko) 2011-01-18
PL402550A1 (pl) 2013-08-05
KR20050056903A (ko) 2005-06-16
DE60204584D1 (de) 2005-07-14
DE60204584T2 (de) 2006-03-16
HUP0401672A2 (hu) 2005-07-28
WO2003037382A1 (en) 2003-05-08

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