PL402550A1 - Dopochwowe kompozycje farmaceutyczne oraz zastosowanie zródla nadtlenku i bioadhezyjnego nosnika - Google Patents

Dopochwowe kompozycje farmaceutyczne oraz zastosowanie zródla nadtlenku i bioadhezyjnego nosnika

Info

Publication number
PL402550A1
PL402550A1 PL402550A PL40255002A PL402550A1 PL 402550 A1 PL402550 A1 PL 402550A1 PL 402550 A PL402550 A PL 402550A PL 40255002 A PL40255002 A PL 40255002A PL 402550 A1 PL402550 A1 PL 402550A1
Authority
PL
Poland
Prior art keywords
peroxide source
pharmaceutical composition
bioadhesive
bioadhesive carrier
peroxide
Prior art date
Application number
PL402550A
Other languages
English (en)
Inventor
William J. Bologna
Howard L. Levine
Original Assignee
Columbia Laboratories (Bermuda) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Laboratories (Bermuda) Limited filed Critical Columbia Laboratories (Bermuda) Limited
Publication of PL402550A1 publication Critical patent/PL402550A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Przedmiotem wynalazku jest dopochwowa kompozycja farmaceutyczna do leczenia lub zapobiegania zakazeniom pochwy zawierajaca zródlo nadtlenku i bioadhezyjny preparat o przedluzonym uwalnianiu. Kompozycja obniza pH i zawiera nadtlenek w ilosci wystarczajacej do zwiekszenia stezenia tlenu, bez wyjalawiania lub nadmiernego niszczenia naturalnie wystepujacej flory bakteryjnej pochwy. Ponadto, przedmiotem wynalazku jest zastosowanie zródla nadtlenku i bioadhezyjnego preparatu o przedluzonym uwalnianiu do wytwarzania leku do podawania dopochwowego.
PL402550A 2001-10-29 2002-10-28 Dopochwowe kompozycje farmaceutyczne oraz zastosowanie zródla nadtlenku i bioadhezyjnego nosnika PL402550A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33068301P 2001-10-29 2001-10-29
US10/278,910 US7709026B2 (en) 2001-10-29 2002-10-24 Low concentration of peroxide for treating or preventing vaginal infections

Publications (1)

Publication Number Publication Date
PL402550A1 true PL402550A1 (pl) 2013-08-05

Family

ID=26959335

Family Applications (2)

Application Number Title Priority Date Filing Date
PL369725A PL216746B1 (pl) 2001-10-29 2002-10-28 Dopochwowa kompozycja farmaceutyczna i zastosowanie źródła nadtlenku oraz polikarbofilu
PL402550A PL402550A1 (pl) 2001-10-29 2002-10-28 Dopochwowe kompozycje farmaceutyczne oraz zastosowanie zródla nadtlenku i bioadhezyjnego nosnika

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL369725A PL216746B1 (pl) 2001-10-29 2002-10-28 Dopochwowa kompozycja farmaceutyczna i zastosowanie źródła nadtlenku oraz polikarbofilu

Country Status (31)

Country Link
US (1) US7709026B2 (pl)
EP (1) EP1441769B1 (pl)
JP (2) JP5153049B2 (pl)
KR (1) KR101009146B1 (pl)
CN (1) CN1578676A (pl)
AR (1) AR037047A1 (pl)
AT (1) ATE297222T1 (pl)
AU (1) AU2002346897B2 (pl)
BR (1) BR0213584A (pl)
CA (1) CA2465133C (pl)
DE (1) DE60204584T2 (pl)
DK (1) DK1441769T3 (pl)
ES (1) ES2243772T3 (pl)
HK (1) HK1063290A1 (pl)
HR (1) HRP20040480B1 (pl)
HU (1) HU229487B1 (pl)
IL (2) IL161512A0 (pl)
MA (1) MA26289A1 (pl)
ME (1) MEP34608A (pl)
MX (1) MXPA04003977A (pl)
MY (1) MY137791A (pl)
NO (1) NO20042199L (pl)
NZ (1) NZ532294A (pl)
PE (1) PE20030492A1 (pl)
PL (2) PL216746B1 (pl)
PT (1) PT1441769E (pl)
RS (1) RS51154B (pl)
RU (1) RU2329829C2 (pl)
SI (1) SI1441769T1 (pl)
WO (1) WO2003037382A1 (pl)
ZA (1) ZA200402943B (pl)

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US20040126369A1 (en) * 2002-12-30 2004-07-01 Richard Payne Delivery of peroxide-generating enzymes to the vaginal tract
DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
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Also Published As

Publication number Publication date
NO20042199L (no) 2004-05-26
MA26289A1 (fr) 2004-09-01
PT1441769E (pt) 2005-08-31
AU2002346897B2 (en) 2008-04-17
PE20030492A1 (es) 2003-06-16
CA2465133C (en) 2012-03-06
IL161512A0 (en) 2004-09-27
HRP20040480A2 (en) 2004-10-31
HUP0401672A2 (hu) 2005-07-28
JP5153049B2 (ja) 2013-02-27
CA2465133A1 (en) 2003-05-08
ATE297222T1 (de) 2005-06-15
BR0213584A (pt) 2004-08-24
HUP0401672A3 (en) 2008-04-28
IL161512A (en) 2009-07-20
JP2010248232A (ja) 2010-11-04
US20030091644A1 (en) 2003-05-15
PL216746B1 (pl) 2014-05-30
EP1441769B1 (en) 2005-06-08
RU2329829C2 (ru) 2008-07-27
ZA200402943B (en) 2005-03-30
RS51154B (sr) 2010-10-31
EP1441769A1 (en) 2004-08-04
AR037047A1 (es) 2004-10-20
JP2005510505A (ja) 2005-04-21
CN1578676A (zh) 2005-02-09
RU2004116312A (ru) 2005-04-10
SI1441769T1 (sl) 2005-12-31
KR20050056903A (ko) 2005-06-16
DE60204584T2 (de) 2006-03-16
RS36604A (en) 2006-12-15
NZ532294A (en) 2006-12-22
DE60204584D1 (de) 2005-07-14
PL369725A1 (pl) 2005-05-02
MEP34608A (en) 2011-02-10
MXPA04003977A (es) 2004-07-08
WO2003037382A1 (en) 2003-05-08
ES2243772T3 (es) 2005-12-01
MY137791A (en) 2009-03-31
HU229487B1 (en) 2014-01-28
DK1441769T3 (da) 2005-09-12
US7709026B2 (en) 2010-05-04
KR101009146B1 (ko) 2011-01-18
HK1063290A1 (en) 2004-12-24
HRP20040480B1 (en) 2007-11-30

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