PE20030492A1 - Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales - Google Patents

Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales

Info

Publication number
PE20030492A1
PE20030492A1 PE2002001057A PE2002001057A PE20030492A1 PE 20030492 A1 PE20030492 A1 PE 20030492A1 PE 2002001057 A PE2002001057 A PE 2002001057A PE 2002001057 A PE2002001057 A PE 2002001057A PE 20030492 A1 PE20030492 A1 PE 20030492A1
Authority
PE
Peru
Prior art keywords
treatment
concentration
prevention
peroxide concentration
peroxide
Prior art date
Application number
PE2002001057A
Other languages
English (en)
Inventor
William J Bologna
Howard L Levine
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Publication of PE20030492A1 publication Critical patent/PE20030492A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA DE LIBERACION PROLONGADA QUE COMPRENDE UNA MEZCLA SINERGICA DE UNA FUENTE DE PEROXIDO EN UNA CANTIDAD DE 0,01mg A 500mg SELECCIONADO DE PEROXIDO DE CARBAMIDA Y UN BIOADHESIVO TAL COMO UN POLIMERO POLICARBOXILICO, QUE SE HINCHA EN EL AGUA Y QUE ES SOLUBLE EN LA MISMA SELECCIONADO DE POLICARBOFILO, CARACTERIZADA PORQUE SE MANTIENE UNA MUY BAJA CONCENTRACION DE PEROXIDO QUE SE LIBERA DURANTE UN PERIODO PROLONGADO DE AL MENOS 12 HORAS, EN UNA CANTIDAD SUFICIENTE PARA AUMENTAR LA CONCENTRACION DEL OXIGENO EN LA VAGINA, PROPORCIONANDO BENEFICIOS AL DISMINUIR EL pH DE LA VAGINA SIN ESTERILIZACION O SIN ELIMINACION DE LA FLORA VAGINAL LOCAL NORMALMENTE DESEADA. LA COMPOSICION PUEDE SER UTIL PARA EL TRATAMIENTO DE INFECCIONES VAGINALES
PE2002001057A 2001-10-29 2002-10-28 Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales PE20030492A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33068301P 2001-10-29 2001-10-29
US10/278,910 US7709026B2 (en) 2001-10-29 2002-10-24 Low concentration of peroxide for treating or preventing vaginal infections

Publications (1)

Publication Number Publication Date
PE20030492A1 true PE20030492A1 (es) 2003-06-16

Family

ID=26959335

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002001057A PE20030492A1 (es) 2001-10-29 2002-10-28 Baja concentracion de peroxido para el tratamiento o prevencion de enfermedades vaginales

Country Status (31)

Country Link
US (1) US7709026B2 (es)
EP (1) EP1441769B1 (es)
JP (2) JP5153049B2 (es)
KR (1) KR101009146B1 (es)
CN (1) CN1578676A (es)
AR (1) AR037047A1 (es)
AT (1) ATE297222T1 (es)
AU (1) AU2002346897B2 (es)
BR (1) BR0213584A (es)
CA (1) CA2465133C (es)
DE (1) DE60204584T2 (es)
DK (1) DK1441769T3 (es)
ES (1) ES2243772T3 (es)
HK (1) HK1063290A1 (es)
HR (1) HRP20040480B1 (es)
HU (1) HU229487B1 (es)
IL (2) IL161512A0 (es)
MA (1) MA26289A1 (es)
ME (1) MEP34608A (es)
MX (1) MXPA04003977A (es)
MY (1) MY137791A (es)
NO (1) NO20042199L (es)
NZ (1) NZ532294A (es)
PE (1) PE20030492A1 (es)
PL (2) PL216746B1 (es)
PT (1) PT1441769E (es)
RS (1) RS51154B (es)
RU (1) RU2329829C2 (es)
SI (1) SI1441769T1 (es)
WO (1) WO2003037382A1 (es)
ZA (1) ZA200402943B (es)

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US20040126369A1 (en) * 2002-12-30 2004-07-01 Richard Payne Delivery of peroxide-generating enzymes to the vaginal tract
DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
ES2237298B1 (es) 2003-07-16 2006-11-01 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.
US20050276865A1 (en) * 2004-05-20 2005-12-15 Servet Buyuktimkin Peroxide compounds for the prevention and treatment of sexual dysfunction in humans
DE102004054552A1 (de) * 2004-11-11 2006-05-18 Hcb Happy Child Birth Holding Ag Neue Zusammensetzung zur Erleichterung der Humangeburt
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US10383894B2 (en) * 2010-03-17 2019-08-20 Lutran Industries, Inc. Human medicinal treatment using salt of peroxymonosulfuric acid
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Also Published As

Publication number Publication date
DK1441769T3 (da) 2005-09-12
MXPA04003977A (es) 2004-07-08
MY137791A (en) 2009-03-31
EP1441769B1 (en) 2005-06-08
PL369725A1 (en) 2005-05-02
PL402550A1 (pl) 2013-08-05
RS36604A (en) 2006-12-15
RU2329829C2 (ru) 2008-07-27
JP2010248232A (ja) 2010-11-04
IL161512A (en) 2009-07-20
AU2002346897B2 (en) 2008-04-17
HRP20040480B1 (en) 2007-11-30
PL216746B1 (pl) 2014-05-30
NO20042199L (no) 2004-05-26
AR037047A1 (es) 2004-10-20
JP2005510505A (ja) 2005-04-21
HU229487B1 (en) 2014-01-28
HK1063290A1 (en) 2004-12-24
CN1578676A (zh) 2005-02-09
MEP34608A (en) 2011-02-10
NZ532294A (en) 2006-12-22
ES2243772T3 (es) 2005-12-01
ATE297222T1 (de) 2005-06-15
CA2465133C (en) 2012-03-06
ZA200402943B (en) 2005-03-30
RU2004116312A (ru) 2005-04-10
IL161512A0 (en) 2004-09-27
RS51154B (sr) 2010-10-31
DE60204584T2 (de) 2006-03-16
US20030091644A1 (en) 2003-05-15
EP1441769A1 (en) 2004-08-04
PT1441769E (pt) 2005-08-31
HUP0401672A3 (en) 2008-04-28
US7709026B2 (en) 2010-05-04
SI1441769T1 (sl) 2005-12-31
KR20050056903A (ko) 2005-06-16
HRP20040480A2 (en) 2004-10-31
MA26289A1 (fr) 2004-09-01
DE60204584D1 (de) 2005-07-14
CA2465133A1 (en) 2003-05-08
JP5153049B2 (ja) 2013-02-27
BR0213584A (pt) 2004-08-24
HUP0401672A2 (hu) 2005-07-28
WO2003037382A1 (en) 2003-05-08
KR101009146B1 (ko) 2011-01-18

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