DE60109938D1 - Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels - Google Patents

Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels

Info

Publication number
DE60109938D1
DE60109938D1 DE60109938T DE60109938T DE60109938D1 DE 60109938 D1 DE60109938 D1 DE 60109938D1 DE 60109938 T DE60109938 T DE 60109938T DE 60109938 T DE60109938 T DE 60109938T DE 60109938 D1 DE60109938 D1 DE 60109938D1
Authority
DE
Germany
Prior art keywords
styleneoid
triglycerid
mirror
compositions
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60109938T
Other languages
English (en)
Other versions
DE60109938T2 (de
Inventor
D Inman
Craig Hoppe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insmed Inc
Original Assignee
Insmed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insmed Inc filed Critical Insmed Inc
Application granted granted Critical
Publication of DE60109938D1 publication Critical patent/DE60109938D1/de
Publication of DE60109938T2 publication Critical patent/DE60109938T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DE60109938T 2000-08-16 2001-08-15 Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels Expired - Lifetime DE60109938T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22570400P 2000-08-16 2000-08-16
US225704P 2000-08-16
US920304 2001-08-02
US09/920,304 US6541522B2 (en) 2000-08-16 2001-08-02 Methods of using compositions containing hypotriglyceridemically active stilbenoids
PCT/US2001/025383 WO2002013806A2 (en) 2000-08-16 2001-08-15 Compositions containing hypotriglyceridemically active stilbenoids

Publications (2)

Publication Number Publication Date
DE60109938D1 true DE60109938D1 (de) 2005-05-12
DE60109938T2 DE60109938T2 (de) 2005-09-08

Family

ID=26919840

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60109938T Expired - Lifetime DE60109938T2 (de) 2000-08-16 2001-08-15 Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels

Country Status (6)

Country Link
US (1) US6541522B2 (de)
EP (1) EP1311258B1 (de)
AT (1) ATE292460T1 (de)
AU (1) AU2001283355A1 (de)
DE (1) DE60109938T2 (de)
WO (1) WO2002013806A2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
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US20020058708A1 (en) * 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6552085B2 (en) * 2000-08-16 2003-04-22 Insmed Incorporated Compositions containing hypoglycemically active stilbenoids
US6410596B1 (en) * 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids
US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
US20050080024A1 (en) * 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives for the treatment of cardiovascular disorders
US20050080021A1 (en) * 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders
CA2529510A1 (en) * 2003-07-01 2005-01-13 President And Fellows Of Harvard College Compositions for manipulating the lifespan and stress response of cells and organisms
US20060025337A1 (en) * 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
US8017634B2 (en) * 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
AU2004312072B2 (en) 2003-12-29 2011-06-23 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
AR047658A1 (es) 2004-02-03 2006-02-01 Cargill Inc Concentrado de proteinas y corriente acuosa con carbohidratos hidrosolubles
CA2570121A1 (en) * 2004-06-16 2006-01-19 President And Fellows Of Harvard College Methods and compositions for modulating bax-ku70-mediated apoptosis
WO2006004722A2 (en) * 2004-06-30 2006-01-12 Biomol Research Laboratories, Inc. Compositions and methods for selectively activating human sirtuins
EP1838296B1 (de) * 2004-10-20 2012-08-08 Resverlogix Corp. Flavonoide und isoflavonoide zur vorbeugung und behandlung cardiovasculärer erkrankungen
WO2006138418A2 (en) * 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20070149466A1 (en) * 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
US8410109B2 (en) * 2005-07-29 2013-04-02 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
US20070029101A1 (en) * 2005-08-05 2007-02-08 Paul Croas Hammerhead forcible entry tool used to defeat burglar bars
WO2008075528A1 (ja) * 2006-12-20 2008-06-26 Kurohime Medical Co., Ltd. 甘茶の用途
JP5236664B2 (ja) 2007-02-01 2013-07-17 レスバーロジックス コーポレイション 心血管疾患を予防および治療するための化合物
US7824714B2 (en) * 2008-06-13 2010-11-02 Development Center For Biotechnology Chinese herb extract for treating dementia and preparation method thereof
AU2009262252B2 (en) 2008-06-26 2013-05-02 Resverlogix Corp. Methods of preparing quinazolinone derivatives
JP5635535B2 (ja) 2009-01-08 2014-12-03 レスバーロジックス コーポレイション 心血管疾患の予防および治療のための化合物
NZ595747A (en) 2009-03-18 2015-06-26 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
DK2421533T3 (en) 2009-04-22 2019-01-07 Resverlogix Corp Hitherto unknown anti-inflammatory agents
US8815310B2 (en) * 2011-01-10 2014-08-26 Morteza Naghavi Compositions for boosting metabolism, assisting weight loss, and promoting cardiovascular health
CN103945848B (zh) 2011-11-01 2016-09-07 雷斯韦洛吉克斯公司 被取代的喹唑啉酮的口服即释制剂
CN103172512B (zh) * 2011-12-23 2016-08-03 中国医学科学院医药生物技术研究所 一组木豆素结构类似化合物、制备方法和应用
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
CN105073744B (zh) 2012-12-21 2019-11-08 齐尼思表观遗传学有限公司 作为溴结构域抑制剂的新型杂环化合物
EP2801357A1 (de) * 2013-05-10 2014-11-12 IMD Natural Solutions GmbH Carboxylierte Stilbene zur Aktivierung von AMPK und Sirtuinen
CN103992290B (zh) * 2013-05-14 2016-07-06 中国医学科学院医药生物技术研究所 二芳基乙烯结构类似化合物及其制备方法和应用
CN104547001A (zh) * 2015-01-09 2015-04-29 刘长河 一种从木豆叶中提取抗骨质疏松和降脂物的工艺
CN107530356A (zh) 2015-03-13 2018-01-02 雷斯韦洛吉克斯公司 用于治疗补体相关疾病之组合物及治疗方法
WO2018233841A1 (de) * 2017-06-22 2018-12-27 Symrise Ag Geschmacksmodulierende aromastoffe
CN112175856B (zh) * 2019-07-05 2022-10-21 中粮生物科技股份有限公司 用于枯草芽孢杆菌发酵的固体培养基以及枯草芽孢杆菌固体菌剂及其制备方法和应用
JP2023547641A (ja) * 2020-11-05 2023-11-13 ソシエテ・デ・プロデュイ・ネスレ・エス・アー Ａｍｐｋ活性化剤としての置換レゾルシル酸化合物及びその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270529A (ja) * 1986-05-19 1987-11-24 Nippon Haipotsukusu:Kk 抗アレルギ−剤
US5827898A (en) 1996-10-07 1998-10-27 Shaman Pharmaceuticals, Inc. Use of bisphenolic compounds to treat type II diabetes
FR2778337B1 (fr) 1998-05-05 2001-08-31 Inst Nat Sante Rech Med Antagonistes des ligands du recepteur des arylhydrocarbures
EP1133308B1 (de) 1998-11-25 2003-11-12 Nutri Pharma ASA Zusammensetzung enthaltend sojaprotein, diätfasern und phytoestrogen sowie ihre verwendung zur vorbeugung und/oder behandlung von kardiovaskulären erkrankungen
DE10015525A1 (de) 2000-03-30 2001-10-11 Deutsches Krebsforsch Synthetische Derivate von Lunularsäure, Arzneimittel enthaltend diese Verbindung, Verfahren zur Herstellung der Lunularsäurederivate sowie deren Verwendung
US20020058708A1 (en) 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6410596B1 (en) 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids
US6552085B2 (en) 2000-08-16 2003-04-22 Insmed Incorporated Compositions containing hypoglycemically active stilbenoids

Also Published As

Publication number Publication date
EP1311258B1 (de) 2005-04-06
DE60109938T2 (de) 2005-09-08
AU2001283355A1 (en) 2002-02-25
EP1311258A2 (de) 2003-05-21
ATE292460T1 (de) 2005-04-15
US6541522B2 (en) 2003-04-01
WO2002013806A2 (en) 2002-02-21
US20020055541A1 (en) 2002-05-09
WO2002013806A3 (en) 2002-10-31

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