AR026186A1 - Metodo para construir cepas geneticamente modificadas de microorganismos degradadores de esteroides que carecen de la capacidad para degradar el nucleo delos esteroides - Google Patents

Metodo para construir cepas geneticamente modificadas de microorganismos degradadores de esteroides que carecen de la capacidad para degradar el nucleo delos esteroides

Info

Publication number
AR026186A1
AR026186A1 ARP000105523A ARP000105523A AR026186A1 AR 026186 A1 AR026186 A1 AR 026186A1 AR P000105523 A ARP000105523 A AR P000105523A AR P000105523 A ARP000105523 A AR P000105523A AR 026186 A1 AR026186 A1 AR 026186A1
Authority
AR
Argentina
Prior art keywords
steroid
steroids
genetically modified
nucleus
degrad
Prior art date
Application number
ARP000105523A
Other languages
English (en)
Spanish (es)
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of AR026186A1 publication Critical patent/AR026186A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ARP000105523A 1999-10-22 2000-10-20 Metodo para construir cepas geneticamente modificadas de microorganismos degradadores de esteroides que carecen de la capacidad para degradar el nucleo delos esteroides AR026186A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203470 1999-10-22
EP99204449 1999-12-22

Publications (1)

Publication Number Publication Date
AR026186A1 true AR026186A1 (es) 2003-01-29

Family

ID=26153382

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000105523A AR026186A1 (es) 1999-10-22 2000-10-20 Metodo para construir cepas geneticamente modificadas de microorganismos degradadores de esteroides que carecen de la capacidad para degradar el nucleo delos esteroides

Country Status (11)

Country Link
EP (1) EP1232278A1 (cs)
CN (1) CN1224716C (cs)
AR (1) AR026186A1 (cs)
AU (1) AU775476B2 (cs)
CA (1) CA2396879A1 (cs)
CZ (1) CZ20021784A3 (cs)
IL (1) IL149715A0 (cs)
NO (1) NO20022449L (cs)
NZ (1) NZ519039A (cs)
RU (1) RU2268935C2 (cs)
WO (1) WO2001031050A1 (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE465247T1 (de) 2002-02-21 2010-05-15 Organon Nv Identifikation von 3-ketosteroid 9-alfa- hydroxylase genen und blockierte mikroorganismen in 3-ketosteroid 9-alfa-hydroxylase aktivität
WO2004055189A1 (en) * 2002-12-03 2004-07-01 Akzo Nobel N.V. New expression system from rhodococcus
AT503486B1 (de) * 2006-04-11 2008-05-15 Iep Gmbh Verfahren zur enantioselektiven reduktion von steroiden
RU2351645C1 (ru) * 2007-07-20 2009-04-10 Наталия Евгеньевна Войшвилло ШТАММ Rhodococcus erythropolis ВКПМ Ac-1740 ДЛЯ ПОЛУЧЕНИЯ 9 АЛЬФА-ГИДРОКСИСТЕРОИДОВ
WO2009024572A1 (en) * 2007-08-21 2009-02-26 N.V. Organon Method for the production of modified steroid degrading microorganisms and their use
RU2011138954A (ru) 2009-02-23 2013-03-27 Рейксюниверситейт Гронинген Фармацевтическая композиция и способы лечения туберкулеза
CN103361394B (zh) * 2013-08-07 2016-08-17 中国科学院上海高等研究院 利用微生物转化制备9α-羟基-雄烯二酮的方法
CN103805577A (zh) * 2013-08-14 2014-05-21 济南环亿生物科技有限公司 一种采用睾丸酮丛毛单胞菌高效生产羟基类固醇脱氢酶的方法
WO2015128534A1 (es) 2014-02-27 2015-09-03 Consejo Superior De Investigaciones Científicas MUTANTES RECOMBINANTES SELECTIVOS DE MYCOBACTERIUM SMEGMATIS mc2 155 Y SU USO PARA LA PRODUCCIÓN DE 1,4-ANDROSTADIEN-3,17-DIONA O 4-ANDROSTEN-3,17-DIONA A PARTIR DE ESTEROLES NATURALES
CN107586762A (zh) * 2017-09-18 2018-01-16 天津科技大学 一种3‑甾酮‑δ1‑脱氢酶突变体及其应用
CN107955827B (zh) * 2017-12-15 2019-07-02 江南大学 一种酶法转化生产9α-羟基雄甾-4-烯-3,17-二酮的方法
US11001871B2 (en) 2017-12-15 2021-05-11 Jiangnan University Method for producing 9alpha-hydroxy androstane-4-alkene-3,17-diketone by enzymatic conversion
GB2577037A (en) * 2018-08-09 2020-03-18 Cambrex Karlskoga Ab Genetically-modified bacteria and uses thereof
AU2020219424A1 (en) * 2019-02-08 2021-08-26 Euroapi France Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids
CN110229838B (zh) * 2019-05-28 2021-01-08 浙江理工大学 一种生物转化类固醇类化合物获取羟基化化合物的方法
CN114621965B (zh) * 2022-02-15 2023-10-03 复旦大学 一种3-甾酮-δ1-脱氢酶突变体及应用
CN120366249A (zh) * 2025-04-23 2025-07-25 浙江工业大学 一种3-甾酮-δ1-脱氢酶突变体及在催化甾体化合物脱氢中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196627B (en) * 1986-11-18 1988-12-28 Gyogyszerkutato Intezet Microbiological process for producing y alpha-hydroxy-4-androstene-3,17-dione
RU2039824C1 (ru) * 1993-06-22 1995-07-20 Институт биохимии и физиологии микроорганизмов РАН Способ получения андроста-1,4-диен-3,17-диона

Also Published As

Publication number Publication date
CA2396879A1 (en) 2001-05-03
RU2002113373A (ru) 2004-02-27
CN1224716C (zh) 2005-10-26
CZ20021784A3 (cs) 2002-08-14
EP1232278A1 (en) 2002-08-21
IL149715A0 (en) 2002-11-10
NO20022449D0 (no) 2002-05-23
WO2001031050A1 (en) 2001-05-03
AU1514501A (en) 2001-05-08
AU775476B2 (en) 2004-08-05
CN1413260A (zh) 2003-04-23
NZ519039A (en) 2004-09-24
NO20022449L (no) 2002-06-19
RU2268935C2 (ru) 2006-01-27

Similar Documents

Publication Publication Date Title
AR026186A1 (es) Metodo para construir cepas geneticamente modificadas de microorganismos degradadores de esteroides que carecen de la capacidad para degradar el nucleo delos esteroides
Al-Hinai et al. The Clostridium sporulation programs: diversity and preservation of endospore differentiation
Dong et al. Efficient genome editing in Aspergillus niger with an improved recyclable CRISPR-HDR toolbox and its application in introducing multiple copies of heterologous genes
WO2007089677A3 (en) Systems and methods for producing biofuels and related materials
MX9606476A (es) Inhibicion citoplasmica de expresion de genes.
BR0214366A (pt) construção de ácido nucleico recombinante, célula e, métodos para produzir ácido láctico, e para reduzir a atividade de piruvato descarboxilase em uma célula
US10351891B2 (en) Hydroxyacyl-coenzyme A dehydrogenase gene, an acyl-coenzyme A thiolase gene, genetically engineered strains and a use thereof
MX2010002990A (es) Produccion de isoprenoides.
MX2009009371A (es) Produccion mejorada de derivados de acidos grasos.
WO2008079469A3 (en) Genetically engineered biological indicator
MY156588A (en) Systems using cell culture for production of isoprene
BR112017020474A2 (pt) levedura modificada, meio de fermentação, método para produção de um bioproduto, ácido nucleico, vetor e método de fermentação para produzir etanol
JP2017537656A5 (cs)
NZ599479A (en) Improved reverse genetics methods for virus rescue
Faramarzi et al. MICROALGAL BIOTRANSFORMATION OF STEROIDS 1
MX2021013856A (es) Métodos para la producción de aglicona de estrictosidina y alcaloides indol monoterpenoides.
EP4635527A3 (en) Thymic constructs and uses thereof
US9567563B2 (en) Aspergillus mutant strain and transformant thereof
MY198223A (en) Cell Culture Medium For Eukaryotic Cells
BR112014026885A2 (pt) método para produzir etanol mediante fermentação de um produto de grãos integrais
MX2021011185A (es) Produccion microbiana de compuestos.
CA3080641C (en) Commercial hopper grain bin assembly method
EP3322806B1 (en) Base sequence for protein expression and method for producing protein using same
ATE299178T1 (de) Verfahren zur herstellung von säugetier-zellinien
WO2009113101A3 (en) Genetically transformed microorganism for biomass fermentation

Legal Events

Date Code Title Description
FA Abandonment or withdrawal