IL149715A0 - MICROBIAL 9α-HYDROXYLATION OF STEROIDS - Google Patents

MICROBIAL 9α-HYDROXYLATION OF STEROIDS

Info

Publication number
IL149715A0
IL149715A0 IL14971500A IL14971500A IL149715A0 IL 149715 A0 IL149715 A0 IL 149715A0 IL 14971500 A IL14971500 A IL 14971500A IL 14971500 A IL14971500 A IL 14971500A IL 149715 A0 IL149715 A0 IL 149715A0
Authority
IL
Israel
Prior art keywords
hydroxylation
steroids
microbial
Prior art date
Application number
IL14971500A
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of IL149715A0 publication Critical patent/IL149715A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
IL14971500A 1999-10-22 2000-10-17 MICROBIAL 9α-HYDROXYLATION OF STEROIDS IL149715A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99203470 1999-10-22
EP99204449 1999-12-22
PCT/EP2000/010223 WO2001031050A1 (en) 1999-10-22 2000-10-17 MICROBIAL 9α-HYDROXYLATION OF STEROIDS

Publications (1)

Publication Number Publication Date
IL149715A0 true IL149715A0 (en) 2002-11-10

Family

ID=26153382

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14971500A IL149715A0 (en) 1999-10-22 2000-10-17 MICROBIAL 9α-HYDROXYLATION OF STEROIDS

Country Status (11)

Country Link
EP (1) EP1232278A1 (en)
CN (1) CN1224716C (en)
AR (1) AR026186A1 (en)
AU (1) AU775476B2 (en)
CA (1) CA2396879A1 (en)
CZ (1) CZ20021784A3 (en)
IL (1) IL149715A0 (en)
NO (1) NO20022449L (en)
NZ (1) NZ519039A (en)
RU (1) RU2268935C2 (en)
WO (1) WO2001031050A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003219134A1 (en) 2002-02-21 2003-09-09 Akzo Nobel N.V. Identification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity
AU2003302151A1 (en) * 2002-12-03 2004-07-09 N.V. Organon New expression system from rhodococcus
AT503486B1 (en) * 2006-04-11 2008-05-15 Iep Gmbh METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF STEROIDS
WO2009024572A1 (en) * 2007-08-21 2009-02-26 N.V. Organon Method for the production of modified steroid degrading microorganisms and their use
CN102413876A (en) 2009-02-23 2012-04-11 格罗宁根大学 Pharmaceutical compositions and methods for treating tuberculosis
CN103361394B (en) * 2013-08-07 2016-08-17 中国科学院上海高等研究院 Utilize the method that microorganism converts preparation 9 Alpha-hydroxies-androstenedione
CN103805577A (en) * 2013-08-14 2014-05-21 济南环亿生物科技有限公司 Method for efficiently producing hydroxysteroid dehydrogenase with testosterone comamonas
WO2015128534A1 (en) 2014-02-27 2015-09-03 Consejo Superior De Investigaciones Científicas Selective recombinant mutants of mycobacterium smegmatis mc2 155 and use thereof for producing 1,4-androstadiene-3,17-dione or 4-androstene-3,17-dione from natural sterols
CN107586762A (en) * 2017-09-18 2018-01-16 天津科技大学 A kind of dehydrogenase mutant of 3 sterone Δ 1 and its application
CN107955827B (en) * 2017-12-15 2019-07-02 江南大学 A kind of 9 Alpha-hydroxy androstane-4-alkene-3s of enzymatic conversion method production, the method for 17- diketone
US11001871B2 (en) 2017-12-15 2021-05-11 Jiangnan University Method for producing 9alpha-hydroxy androstane-4-alkene-3,17-diketone by enzymatic conversion
GB2577037A (en) * 2018-08-09 2020-03-18 Cambrex Karlskoga Ab Genetically-modified bacteria and uses thereof
CN110229838B (en) * 2019-05-28 2021-01-08 浙江理工大学 Method for obtaining hydroxylated compound by biotransformation of steroid compound
CN114621965B (en) * 2022-02-15 2023-10-03 复旦大学 3-sterone-delta 1 Dehydrogenase mutants and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196627B (en) * 1986-11-18 1988-12-28 Gyogyszerkutato Intezet Microbiological process for producing y alpha-hydroxy-4-androstene-3,17-dione

Also Published As

Publication number Publication date
CN1413260A (en) 2003-04-23
WO2001031050A1 (en) 2001-05-03
CA2396879A1 (en) 2001-05-03
NO20022449L (en) 2002-06-19
AR026186A1 (en) 2003-01-29
NO20022449D0 (en) 2002-05-23
RU2268935C2 (en) 2006-01-27
NZ519039A (en) 2004-09-24
AU1514501A (en) 2001-05-08
CZ20021784A3 (en) 2002-08-14
CN1224716C (en) 2005-10-26
RU2002113373A (en) 2004-02-27
EP1232278A1 (en) 2002-08-21
AU775476B2 (en) 2004-08-05

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