AR021459A1 - PARCHE QUE CONTIENE ESTRADIOL PARA LA APLICACIoN PERCUTÁNEA DE HORMONAS. - Google Patents
PARCHE QUE CONTIENE ESTRADIOL PARA LA APLICACIoN PERCUTÁNEA DE HORMONAS.Info
- Publication number
- AR021459A1 AR021459A1 ARP990103732A ARP990103732A AR021459A1 AR 021459 A1 AR021459 A1 AR 021459A1 AR P990103732 A ARP990103732 A AR P990103732A AR P990103732 A ARP990103732 A AR P990103732A AR 021459 A1 AR021459 A1 AR 021459A1
- Authority
- AR
- Argentina
- Prior art keywords
- patch containing
- hormones
- active ingredient
- percutaneous application
- containing estradiol
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 2
- 229960005309 estradiol Drugs 0.000 title abstract 2
- 229930182833 estradiol Natural products 0.000 title abstract 2
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 239000004821 Contact adhesive Substances 0.000 abstract 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 239000011241 protective layer Substances 0.000 abstract 1
- 239000011787 zinc oxide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/65—Characterized by the composition of the particulate/core
- A61K2800/651—The particulate/core comprising inorganic material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19834007A DE19834007C1 (de) | 1998-07-29 | 1998-07-29 | Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR021459A1 true AR021459A1 (es) | 2002-07-24 |
Family
ID=7875613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990103732A AR021459A1 (es) | 1998-07-29 | 1999-07-28 | PARCHE QUE CONTIENE ESTRADIOL PARA LA APLICACIoN PERCUTÁNEA DE HORMONAS. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6531149B1 (https=) |
| EP (1) | EP1100477B1 (https=) |
| JP (1) | JP2002521427A (https=) |
| KR (1) | KR100559089B1 (https=) |
| CN (1) | CN1172661C (https=) |
| AR (1) | AR021459A1 (https=) |
| AT (1) | ATE264097T1 (https=) |
| AU (1) | AU758107B2 (https=) |
| BR (1) | BR9912687A (https=) |
| CA (1) | CA2338859C (https=) |
| DE (2) | DE19834007C1 (https=) |
| ES (1) | ES2220093T3 (https=) |
| IL (2) | IL141033A0 (https=) |
| PL (1) | PL194102B1 (https=) |
| TR (1) | TR200100289T2 (https=) |
| TW (1) | TW542726B (https=) |
| WO (1) | WO2000006131A1 (https=) |
| ZA (1) | ZA200100719B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10304988A1 (de) * | 2003-02-07 | 2004-09-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten |
| JP2006525030A (ja) | 2003-05-07 | 2006-11-09 | セダーズ−シナイ メディカル センター | 細胞内エストラジオール結合タンパク質、このタンパク質をコードするポリヌクレオチドおよびこのタンパク質を過剰発現する細胞 |
| US7251128B2 (en) * | 2004-09-30 | 2007-07-31 | Intel Corporation | Adjustable portable computer |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE251567C (https=) | ||||
| NL6902314A (https=) | 1969-02-13 | 1970-08-17 | ||
| US3637224A (en) | 1969-02-27 | 1972-01-25 | Fedders Corp | Annular sealing ring |
| US4379454A (en) | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
| CA1248450A (en) * | 1984-04-05 | 1989-01-10 | Kazuo Kigasawa | Soft patch |
| US4624665A (en) | 1984-10-01 | 1986-11-25 | Biotek, Inc. | Method of transdermal drug delivery |
| US4720489A (en) * | 1984-10-15 | 1988-01-19 | Douglas Shander | Hair growth modification with ornithine decarboxylase inhibitors |
| ATE95430T1 (de) * | 1984-12-22 | 1993-10-15 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster. |
| US4883669A (en) | 1985-02-25 | 1989-11-28 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration |
| DD251567A1 (de) * | 1986-07-30 | 1987-11-18 | Jenapharm Veb | Verfahren zur herstellung gefaerbter, selbstklebender loesungsmittelhaltiger polymermischungen |
| CN1021196C (zh) | 1986-12-29 | 1993-06-16 | 新泽西州州立大学(鲁杰斯) | 透皮雌激素/孕激素药剂单元、系统及方法 |
| CH674618A5 (https=) | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
| DE3743946A1 (de) | 1987-09-01 | 1989-03-09 | Lohmann Gmbh & Co Kg | Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung |
| US4906475A (en) | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| JPH02180835A (ja) * | 1988-12-29 | 1990-07-13 | Lion Corp | 外用製剤 |
| DE69007886T2 (de) * | 1989-07-21 | 1994-11-17 | Izhak Blank | Östradiol enthaltende Mittel und Verfahren zur topischen Anwendung. |
| AU644815B2 (en) * | 1989-09-08 | 1993-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Solid matrix system for transdermal drug delivery |
| JP3273430B2 (ja) * | 1989-12-28 | 2002-04-08 | 日東電工株式会社 | エストロゲン含有ゲル製剤 |
| DE4115849A1 (de) * | 1991-05-15 | 1992-11-19 | Lohmann Therapie Syst Lts | Penetrationsfoerdernde substanz |
| JPH04342532A (ja) * | 1991-05-21 | 1992-11-30 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
| JP3086288B2 (ja) * | 1991-07-23 | 2000-09-11 | 扶桑薬品工業株式会社 | 経皮吸収製剤 |
| JPH05148135A (ja) * | 1991-11-29 | 1993-06-15 | L T T Kenkyusho:Kk | 貼付剤用物理的吸収促進剤及びそれを含む貼付剤 |
| DE4230588C1 (de) * | 1992-09-12 | 1993-10-07 | Lohmann Therapie Syst Lts | Dexpanthenol-haltiges Pflaster zur transdermalen Applikation von Steroidhormonen und Verfahren zu seiner Herstellung |
| JP2569396B2 (ja) * | 1992-12-04 | 1997-01-08 | 株式会社太平洋 | 経皮投与型薬物用貼付剤 |
| JP3197102B2 (ja) * | 1993-03-29 | 2001-08-13 | 積水化学工業株式会社 | 経皮吸収製剤及びその製造方法 |
| JP3305101B2 (ja) * | 1994-03-29 | 2002-07-22 | 積水化学工業株式会社 | 経皮吸収製剤 |
| DE4416927C1 (de) * | 1994-05-13 | 1995-08-31 | Lohmann Therapie Syst Lts | Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung |
| JPH0827003A (ja) * | 1994-07-22 | 1996-01-30 | Sekisui Chem Co Ltd | 経皮吸収製剤 |
| US5820878A (en) * | 1994-11-18 | 1998-10-13 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneously absorbable patch |
| EP0746311B1 (en) * | 1994-12-24 | 2001-07-11 | Pacific Corporation | Medicinal patches for percutaneous administration |
| CA2222133C (en) * | 1995-06-07 | 2002-12-24 | Cygnus, Inc. | Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen |
| US5783208A (en) * | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
| US5948433A (en) * | 1997-08-21 | 1999-09-07 | Bertek, Inc. | Transdermal patch |
-
1998
- 1998-07-29 DE DE19834007A patent/DE19834007C1/de not_active Expired - Fee Related
-
1999
- 1999-07-16 EP EP99936555A patent/EP1100477B1/de not_active Expired - Lifetime
- 1999-07-16 KR KR1020017001313A patent/KR100559089B1/ko not_active Expired - Fee Related
- 1999-07-16 WO PCT/EP1999/005085 patent/WO2000006131A1/de not_active Ceased
- 1999-07-16 AU AU51607/99A patent/AU758107B2/en not_active Ceased
- 1999-07-16 ES ES99936555T patent/ES2220093T3/es not_active Expired - Lifetime
- 1999-07-16 BR BR9912687-7A patent/BR9912687A/pt not_active IP Right Cessation
- 1999-07-16 PL PL99345695A patent/PL194102B1/pl not_active IP Right Cessation
- 1999-07-16 CA CA002338859A patent/CA2338859C/en not_active Expired - Fee Related
- 1999-07-16 AT AT99936555T patent/ATE264097T1/de not_active IP Right Cessation
- 1999-07-16 DE DE59909189T patent/DE59909189D1/de not_active Expired - Lifetime
- 1999-07-16 TR TR2001/00289T patent/TR200100289T2/xx unknown
- 1999-07-16 CN CNB998088528A patent/CN1172661C/zh not_active Expired - Fee Related
- 1999-07-16 IL IL14103399A patent/IL141033A0/xx unknown
- 1999-07-16 JP JP2000561986A patent/JP2002521427A/ja active Pending
- 1999-07-16 US US09/744,711 patent/US6531149B1/en not_active Expired - Fee Related
- 1999-07-22 TW TW088112440A patent/TW542726B/zh not_active IP Right Cessation
- 1999-07-28 AR ARP990103732A patent/AR021459A1/es active IP Right Grant
-
2001
- 2001-01-23 IL IL141033A patent/IL141033A/en not_active IP Right Cessation
- 2001-01-25 ZA ZA200100719A patent/ZA200100719B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL194102B1 (pl) | 2007-04-30 |
| CN1172661C (zh) | 2004-10-27 |
| ATE264097T1 (de) | 2004-04-15 |
| ZA200100719B (en) | 2002-06-14 |
| TR200100289T2 (tr) | 2001-07-23 |
| IL141033A (en) | 2009-06-15 |
| EP1100477A1 (de) | 2001-05-23 |
| ES2220093T3 (es) | 2004-12-01 |
| CA2338859C (en) | 2007-09-18 |
| BR9912687A (pt) | 2001-06-05 |
| PL345695A1 (en) | 2002-01-02 |
| WO2000006131A1 (de) | 2000-02-10 |
| IL141033A0 (en) | 2002-02-10 |
| EP1100477B1 (de) | 2004-04-14 |
| US6531149B1 (en) | 2003-03-11 |
| DE19834007C1 (de) | 2000-02-24 |
| DE59909189D1 (de) | 2004-05-19 |
| TW542726B (en) | 2003-07-21 |
| KR20010079571A (ko) | 2001-08-22 |
| AU758107B2 (en) | 2003-03-13 |
| CN1310614A (zh) | 2001-08-29 |
| JP2002521427A (ja) | 2002-07-16 |
| KR100559089B1 (ko) | 2006-03-13 |
| CA2338859A1 (en) | 2000-02-10 |
| AU5160799A (en) | 2000-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |