TR200100289T2 - Transdermal hormon uygulaması için estradiol içerkli flaster - Google Patents
Transdermal hormon uygulaması için estradiol içerkli flasterInfo
- Publication number
- TR200100289T2 TR200100289T2 TR2001/00289T TR200100289T TR200100289T2 TR 200100289 T2 TR200100289 T2 TR 200100289T2 TR 2001/00289 T TR2001/00289 T TR 2001/00289T TR 200100289 T TR200100289 T TR 200100289T TR 200100289 T2 TR200100289 T2 TR 200100289T2
- Authority
- TR
- Turkey
- Prior art keywords
- estradiol
- containing patch
- hormone administration
- transdermal hormone
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/65—Characterized by the composition of the particulate/core
- A61K2800/651—The particulate/core comprising inorganic material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Estradiolün veya eczacilik açisindan sakinca olusturmayan türevlerinin tek basina veya Gestajenler ile kombinasyon halinde insan veya hayvan cildine kontrollü olarak verilmesi için, bir arka tabakadan, tutucu yapistiricilar kullanilarak imal edilen ve etki maddesinin kombinasyon halinde verilmesine uygun, etki maddesi içeren buna bagli bir rezervuardan ve tekrar çikarilabilen bir koruyucu tabakadan ibaret olan etki maddesi içerikli flasterin özelligi, tutucu yapistiricinin saf balmumu veya bunun unsurlarini veya çinko oksit içermesidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19834007A DE19834007C1 (de) | 1998-07-29 | 1998-07-29 | Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200100289T2 true TR200100289T2 (tr) | 2001-07-23 |
Family
ID=7875613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/00289T TR200100289T2 (tr) | 1998-07-29 | 1999-07-16 | Transdermal hormon uygulaması için estradiol içerkli flaster |
Country Status (18)
Country | Link |
---|---|
US (1) | US6531149B1 (tr) |
EP (1) | EP1100477B1 (tr) |
JP (1) | JP2002521427A (tr) |
KR (1) | KR100559089B1 (tr) |
CN (1) | CN1172661C (tr) |
AR (1) | AR021459A1 (tr) |
AT (1) | ATE264097T1 (tr) |
AU (1) | AU758107B2 (tr) |
BR (1) | BR9912687A (tr) |
CA (1) | CA2338859C (tr) |
DE (2) | DE19834007C1 (tr) |
ES (1) | ES2220093T3 (tr) |
IL (2) | IL141033A0 (tr) |
PL (1) | PL194102B1 (tr) |
TR (1) | TR200100289T2 (tr) |
TW (1) | TW542726B (tr) |
WO (1) | WO2000006131A1 (tr) |
ZA (1) | ZA200100719B (tr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10304988A1 (de) * | 2003-02-07 | 2004-09-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten |
WO2005000198A2 (en) | 2003-05-07 | 2005-01-06 | Cedars-Sinai Medical Center | An intracellular estradiol binding protein, a polynucleotide encoding the same and cell lines overexpressing the same |
US7251128B2 (en) * | 2004-09-30 | 2007-07-31 | Intel Corporation | Adjustable portable computer |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
LT2782584T (lt) | 2011-11-23 | 2021-09-10 | Therapeuticsmd, Inc. | Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE251567C (tr) | ||||
NL6902314A (tr) | 1969-02-13 | 1970-08-17 | ||
US3637224A (en) | 1969-02-27 | 1972-01-25 | Fedders Corp | Annular sealing ring |
US4379454A (en) | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
CA1248450A (en) * | 1984-04-05 | 1989-01-10 | Kazuo Kigasawa | Soft patch |
US4624665A (en) | 1984-10-01 | 1986-11-25 | Biotek, Inc. | Method of transdermal drug delivery |
US4720489A (en) * | 1984-10-15 | 1988-01-19 | Douglas Shander | Hair growth modification with ornithine decarboxylase inhibitors |
ATE95430T1 (de) * | 1984-12-22 | 1993-10-15 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster. |
US4883669A (en) | 1985-02-25 | 1989-11-28 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration |
DD251567A1 (de) * | 1986-07-30 | 1987-11-18 | Jenapharm Veb | Verfahren zur herstellung gefaerbter, selbstklebender loesungsmittelhaltiger polymermischungen |
CN1021196C (zh) | 1986-12-29 | 1993-06-16 | 新泽西州州立大学(鲁杰斯) | 透皮雌激素/孕激素药剂单元、系统及方法 |
CH674618A5 (tr) | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
DE3743946A1 (de) | 1987-09-01 | 1989-03-09 | Lohmann Gmbh & Co Kg | Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung |
US4906475A (en) | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
JPH02180835A (ja) * | 1988-12-29 | 1990-07-13 | Lion Corp | 外用製剤 |
EP0409383B1 (en) * | 1989-07-21 | 1994-04-06 | Izhak Blank | Estradiol compositions and methods for topical applications |
AU644815B2 (en) * | 1989-09-08 | 1993-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Solid matrix system for transdermal drug delivery |
JP3273430B2 (ja) * | 1989-12-28 | 2002-04-08 | 日東電工株式会社 | エストロゲン含有ゲル製剤 |
DE4115849A1 (de) * | 1991-05-15 | 1992-11-19 | Lohmann Therapie Syst Lts | Penetrationsfoerdernde substanz |
JPH04342532A (ja) * | 1991-05-21 | 1992-11-30 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
JP3086288B2 (ja) * | 1991-07-23 | 2000-09-11 | 扶桑薬品工業株式会社 | 経皮吸収製剤 |
JPH05148135A (ja) * | 1991-11-29 | 1993-06-15 | L T T Kenkyusho:Kk | 貼付剤用物理的吸収促進剤及びそれを含む貼付剤 |
DE4230588C1 (de) * | 1992-09-12 | 1993-10-07 | Lohmann Therapie Syst Lts | Dexpanthenol-haltiges Pflaster zur transdermalen Applikation von Steroidhormonen und Verfahren zu seiner Herstellung |
JP2569396B2 (ja) * | 1992-12-04 | 1997-01-08 | 株式会社太平洋 | 経皮投与型薬物用貼付剤 |
JP3197102B2 (ja) * | 1993-03-29 | 2001-08-13 | 積水化学工業株式会社 | 経皮吸収製剤及びその製造方法 |
JP3305101B2 (ja) * | 1994-03-29 | 2002-07-22 | 積水化学工業株式会社 | 経皮吸収製剤 |
DE4416927C1 (de) * | 1994-05-13 | 1995-08-31 | Lohmann Therapie Syst Lts | Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung |
JPH0827003A (ja) * | 1994-07-22 | 1996-01-30 | Sekisui Chem Co Ltd | 経皮吸収製剤 |
WO1996015776A1 (fr) * | 1994-11-18 | 1996-05-30 | Hisamitsu Pharmaceutical Co., Inc. | Timbre absorbable par voie percutanee |
EP0746311B1 (en) * | 1994-12-24 | 2001-07-11 | Pacific Corporation | Medicinal patches for percutaneous administration |
UA48973C2 (uk) * | 1995-06-07 | 2002-09-16 | Орто-Макнейл Фармасьютікалз Інк. | Трансдермальний пластир на основі 17-деацетилноргестимату для попередження овуляції |
US5783208A (en) * | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
US5948433A (en) * | 1997-08-21 | 1999-09-07 | Bertek, Inc. | Transdermal patch |
-
1998
- 1998-07-29 DE DE19834007A patent/DE19834007C1/de not_active Expired - Fee Related
-
1999
- 1999-07-16 EP EP99936555A patent/EP1100477B1/de not_active Expired - Lifetime
- 1999-07-16 ES ES99936555T patent/ES2220093T3/es not_active Expired - Lifetime
- 1999-07-16 PL PL99345695A patent/PL194102B1/pl not_active IP Right Cessation
- 1999-07-16 KR KR1020017001313A patent/KR100559089B1/ko not_active IP Right Cessation
- 1999-07-16 AT AT99936555T patent/ATE264097T1/de not_active IP Right Cessation
- 1999-07-16 WO PCT/EP1999/005085 patent/WO2000006131A1/de active IP Right Grant
- 1999-07-16 IL IL14103399A patent/IL141033A0/xx unknown
- 1999-07-16 US US09/744,711 patent/US6531149B1/en not_active Expired - Fee Related
- 1999-07-16 CA CA002338859A patent/CA2338859C/en not_active Expired - Fee Related
- 1999-07-16 AU AU51607/99A patent/AU758107B2/en not_active Ceased
- 1999-07-16 JP JP2000561986A patent/JP2002521427A/ja active Pending
- 1999-07-16 CN CNB998088528A patent/CN1172661C/zh not_active Expired - Fee Related
- 1999-07-16 TR TR2001/00289T patent/TR200100289T2/tr unknown
- 1999-07-16 DE DE59909189T patent/DE59909189D1/de not_active Expired - Lifetime
- 1999-07-16 BR BR9912687-7A patent/BR9912687A/pt not_active IP Right Cessation
- 1999-07-22 TW TW088112440A patent/TW542726B/zh not_active IP Right Cessation
- 1999-07-28 AR ARP990103732A patent/AR021459A1/es active IP Right Grant
-
2001
- 2001-01-23 IL IL141033A patent/IL141033A/en not_active IP Right Cessation
- 2001-01-25 ZA ZA200100719A patent/ZA200100719B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2220093T3 (es) | 2004-12-01 |
CA2338859A1 (en) | 2000-02-10 |
CN1172661C (zh) | 2004-10-27 |
AU5160799A (en) | 2000-02-21 |
AR021459A1 (es) | 2002-07-24 |
ZA200100719B (en) | 2002-06-14 |
ATE264097T1 (de) | 2004-04-15 |
EP1100477B1 (de) | 2004-04-14 |
CA2338859C (en) | 2007-09-18 |
KR100559089B1 (ko) | 2006-03-13 |
TW542726B (en) | 2003-07-21 |
PL194102B1 (pl) | 2007-04-30 |
WO2000006131A1 (de) | 2000-02-10 |
EP1100477A1 (de) | 2001-05-23 |
DE19834007C1 (de) | 2000-02-24 |
JP2002521427A (ja) | 2002-07-16 |
PL345695A1 (en) | 2002-01-02 |
KR20010079571A (ko) | 2001-08-22 |
BR9912687A (pt) | 2001-06-05 |
CN1310614A (zh) | 2001-08-29 |
DE59909189D1 (de) | 2004-05-19 |
US6531149B1 (en) | 2003-03-11 |
IL141033A (en) | 2009-06-15 |
AU758107B2 (en) | 2003-03-13 |
IL141033A0 (en) | 2002-02-10 |
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