TR200100289T2 - Transdermal hormon uygulaması için estradiol içerkli flaster - Google Patents

Transdermal hormon uygulaması için estradiol içerkli flaster

Info

Publication number
TR200100289T2
TR200100289T2 TR2001/00289T TR200100289T TR200100289T2 TR 200100289 T2 TR200100289 T2 TR 200100289T2 TR 2001/00289 T TR2001/00289 T TR 2001/00289T TR 200100289 T TR200100289 T TR 200100289T TR 200100289 T2 TR200100289 T2 TR 200100289T2
Authority
TR
Turkey
Prior art keywords
estradiol
containing patch
hormone administration
transdermal hormone
combination
Prior art date
Application number
TR2001/00289T
Other languages
English (en)
Inventor
Kirstgen Elvira
Meconi Reinhold
Lohmann Therapie- Systeme Ag Lts
Original Assignee
Lohmann Therapie- Systeme Ag Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7875613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200100289(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lohmann Therapie- Systeme Ag Lts filed Critical Lohmann Therapie- Systeme Ag Lts
Publication of TR200100289T2 publication Critical patent/TR200100289T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60Particulates further characterized by their structure or composition
    • A61K2800/65Characterized by the composition of the particulate/core
    • A61K2800/651The particulate/core comprising inorganic material

Abstract

Estradiolün veya eczacilik açisindan sakinca olusturmayan türevlerinin tek basina veya Gestajenler ile kombinasyon halinde insan veya hayvan cildine kontrollü olarak verilmesi için, bir arka tabakadan, tutucu yapistiricilar kullanilarak imal edilen ve etki maddesinin kombinasyon halinde verilmesine uygun, etki maddesi içeren buna bagli bir rezervuardan ve tekrar çikarilabilen bir koruyucu tabakadan ibaret olan etki maddesi içerikli flasterin özelligi, tutucu yapistiricinin saf balmumu veya bunun unsurlarini veya çinko oksit içermesidir.
TR2001/00289T 1998-07-29 1999-07-16 Transdermal hormon uygulaması için estradiol içerkli flaster TR200100289T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19834007A DE19834007C1 (de) 1998-07-29 1998-07-29 Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung

Publications (1)

Publication Number Publication Date
TR200100289T2 true TR200100289T2 (tr) 2001-07-23

Family

ID=7875613

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00289T TR200100289T2 (tr) 1998-07-29 1999-07-16 Transdermal hormon uygulaması için estradiol içerkli flaster

Country Status (18)

Country Link
US (1) US6531149B1 (tr)
EP (1) EP1100477B1 (tr)
JP (1) JP2002521427A (tr)
KR (1) KR100559089B1 (tr)
CN (1) CN1172661C (tr)
AR (1) AR021459A1 (tr)
AT (1) ATE264097T1 (tr)
AU (1) AU758107B2 (tr)
BR (1) BR9912687A (tr)
CA (1) CA2338859C (tr)
DE (2) DE19834007C1 (tr)
ES (1) ES2220093T3 (tr)
IL (2) IL141033A0 (tr)
PL (1) PL194102B1 (tr)
TR (1) TR200100289T2 (tr)
TW (1) TW542726B (tr)
WO (1) WO2000006131A1 (tr)
ZA (1) ZA200100719B (tr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10304988A1 (de) * 2003-02-07 2004-09-09 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten
JP2006525030A (ja) * 2003-05-07 2006-11-09 セダーズ−シナイ メディカル センター 細胞内エストラジオール結合タンパク質、このタンパク質をコードするポリヌクレオチドおよびこのタンパク質を過剰発現する細胞
US7251128B2 (en) * 2004-09-30 2007-07-31 Intel Corporation Adjustable portable computer
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
EP3145489A1 (en) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
BR112018070199A2 (pt) 2016-04-01 2019-01-29 Therapeuticsmd Inc composição farmacêutica de hormônio esteroide
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE251567C (tr)
NL6902314A (tr) 1969-02-13 1970-08-17
US3637224A (en) 1969-02-27 1972-01-25 Fedders Corp Annular sealing ring
US4379454A (en) 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
CA1248450A (en) * 1984-04-05 1989-01-10 Kazuo Kigasawa Soft patch
US4624665A (en) 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
EP0186019B1 (de) * 1984-12-22 1993-10-06 Schwarz Pharma Ag Wirkstoffpflaster
US4883669A (en) 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
DD251567A1 (de) * 1986-07-30 1987-11-18 Jenapharm Veb Verfahren zur herstellung gefaerbter, selbstklebender loesungsmittelhaltiger polymermischungen
CN1021196C (zh) 1986-12-29 1993-06-16 新泽西州州立大学(鲁杰斯) 透皮雌激素/孕激素药剂单元、系统及方法
CH674618A5 (tr) 1987-04-02 1990-06-29 Ciba Geigy Ag
DE3743946A1 (de) 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
US4906475A (en) 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
JPH02180835A (ja) * 1988-12-29 1990-07-13 Lion Corp 外用製剤
DE69007886T2 (de) * 1989-07-21 1994-11-17 Izhak Blank Östradiol enthaltende Mittel und Verfahren zur topischen Anwendung.
CA2065311C (en) * 1989-09-08 2000-01-11 Chia-Ming Chiang Solid matrix system for transdermal drug delivery
JP3273430B2 (ja) * 1989-12-28 2002-04-08 日東電工株式会社 エストロゲン含有ゲル製剤
DE4115849A1 (de) * 1991-05-15 1992-11-19 Lohmann Therapie Syst Lts Penetrationsfoerdernde substanz
JPH04342532A (ja) * 1991-05-21 1992-11-30 Sekisui Chem Co Ltd 経皮吸収貼付剤
JP3086288B2 (ja) * 1991-07-23 2000-09-11 扶桑薬品工業株式会社 経皮吸収製剤
JPH05148135A (ja) * 1991-11-29 1993-06-15 L T T Kenkyusho:Kk 貼付剤用物理的吸収促進剤及びそれを含む貼付剤
DE4230588C1 (de) * 1992-09-12 1993-10-07 Lohmann Therapie Syst Lts Dexpanthenol-haltiges Pflaster zur transdermalen Applikation von Steroidhormonen und Verfahren zu seiner Herstellung
JP2569396B2 (ja) * 1992-12-04 1997-01-08 株式会社太平洋 経皮投与型薬物用貼付剤
JP3197102B2 (ja) * 1993-03-29 2001-08-13 積水化学工業株式会社 経皮吸収製剤及びその製造方法
JP3305101B2 (ja) * 1994-03-29 2002-07-22 積水化学工業株式会社 経皮吸収製剤
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
JPH0827003A (ja) * 1994-07-22 1996-01-30 Sekisui Chem Co Ltd 経皮吸収製剤
AU692944B2 (en) * 1994-11-18 1998-06-18 Hisamitsu Pharmaceutical Co., Inc. Percutaneously absorbable patch
ES2160727T3 (es) * 1994-12-24 2001-11-16 Pacific Corp Parches medicinales para administracion percutanea.
ES2190472T5 (es) * 1995-06-07 2012-03-09 Ortho-Mcneil Pharmaceutical, Inc. Parche transdérmico para la administración de 17-deacetil norgestimato, en combinación con un estrógeno.
US5783208A (en) * 1996-07-19 1998-07-21 Theratech, Inc. Transdermal drug delivery matrix for coadministering estradiol and another steroid
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch

Also Published As

Publication number Publication date
IL141033A (en) 2009-06-15
CA2338859A1 (en) 2000-02-10
KR20010079571A (ko) 2001-08-22
JP2002521427A (ja) 2002-07-16
EP1100477B1 (de) 2004-04-14
AR021459A1 (es) 2002-07-24
AU5160799A (en) 2000-02-21
PL194102B1 (pl) 2007-04-30
CN1172661C (zh) 2004-10-27
IL141033A0 (en) 2002-02-10
ATE264097T1 (de) 2004-04-15
US6531149B1 (en) 2003-03-11
BR9912687A (pt) 2001-06-05
KR100559089B1 (ko) 2006-03-13
PL345695A1 (en) 2002-01-02
WO2000006131A1 (de) 2000-02-10
EP1100477A1 (de) 2001-05-23
TW542726B (en) 2003-07-21
DE19834007C1 (de) 2000-02-24
AU758107B2 (en) 2003-03-13
CA2338859C (en) 2007-09-18
CN1310614A (zh) 2001-08-29
ZA200100719B (en) 2002-06-14
DE59909189D1 (de) 2004-05-19
ES2220093T3 (es) 2004-12-01

Similar Documents

Publication Publication Date Title
TR200100289T2 (tr) Transdermal hormon uygulaması için estradiol içerkli flaster
AU760588B2 (en) Pressure sensitive adhesive matrix patch for the treatment of onychomycosis
KR960703545A (ko) 테스토스테론의 공급을 위한 피부패치 및 방법(skin patches and methods for providing testosterone)
DK0744944T3 (da) Transdermale terapeutiske systemer indeholdende kønssterioder
DE3778223D1 (de) Biologisch erodierbares system mit gesteuerter freisetzung des arzneiwirkstoffes.
NO950051D0 (no) Plaster for lavtsmeltende og/eller flyktige aktive bestanddeler
TR200101033T2 (tr) Akış direnci hafifletilmiş, aerosol halindeki aktif maddenin verilmesi
ATE238778T1 (de) Transdermales therapeutisches system zur abgabe von hormonen
PT1047409E (pt) Tts contendo um antioxidante
JPH07258060A (ja) 皮膚美白用貼付剤
US9700522B2 (en) Transdermal patch and method for delivery of vitamin B12
KR950703972A (ko) 항혈전성 치료 및 암 예방을 위한 아세틸살리실산을 함유하는 경피 투여 시스템(transdermal administration system containing acetylsalicyliic acid for antithrombotic therapy and the prevention of cancer)
ATE128029T1 (de) Transdermales estradiol als therapeutisches system.
Garmyn et al. Mechanisms of and variables affecting UVR photoadaptation in human skin
ES2315309T3 (es) Combinacion de un sistema terapeutico transdermico y de una preparacion oral y/o parenteral que contiene agonistas dopaminergicos para el tratamiento de ebfermedades dopaminergicas.
JP2002521427A5 (tr)
TR200003839T2 (tr) Hormon ve kristalleşmeyi engelleyen maddeler içeren transdermal terapi sistemi
US5156846A (en) Percutaneous drug delivery system
CO5011044A1 (es) Filtro solar con color que desaparece funciona como filtro solar
TR200100290T2 (tr) Transdermal hormon uygulaması için estradiol içerikli flaster
ZA200200519B (en) Transdermal delivery of lasofoxifene.
ATE214606T1 (de) Transdermales therapeutisches system mit dem wirkstoff scopolaminbase
GB1292545A (en) Medical plaster
TR200000249T2 (tr) Bir etki maddesinin deri üzerinden bir organizmaya geçirilmesi ve deri üzerine tatbik işlemine dair transdermal terapötik sistem (TTS)
AR019133A1 (es) Filtro solar con indicador de color que desaparece