AR018013A1 - Una proteina de alto peso molecular (hmw) aislada de especies de chlamydia y los acidos nucleicos, vectores de expresion recombinante, celulas huespedtransformadas, proteinas recombinantes, composiciones inmunogenicas y antigenicas, metodos para producir una respuesta inmune en animales, antisueros, - Google Patents

Una proteina de alto peso molecular (hmw) aislada de especies de chlamydia y los acidos nucleicos, vectores de expresion recombinante, celulas huespedtransformadas, proteinas recombinantes, composiciones inmunogenicas y antigenicas, metodos para producir una respuesta inmune en animales, antisueros,

Info

Publication number
AR018013A1
AR018013A1 ARP980104960A ARP980104960A AR018013A1 AR 018013 A1 AR018013 A1 AR 018013A1 AR P980104960 A ARP980104960 A AR P980104960A AR P980104960 A ARP980104960 A AR P980104960A AR 018013 A1 AR018013 A1 AR 018013A1
Authority
AR
Argentina
Prior art keywords
chlamydia
species
promotional
nucleic acids
methods
Prior art date
Application number
ARP980104960A
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English (en)
Original Assignee
Antex Biolog Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antex Biolog Inc filed Critical Antex Biolog Inc
Publication of AR018013A1 publication Critical patent/AR018013A1/es

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56927Chlamydia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/125Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Chlamydiales (O)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/295Assays involving biological materials from specific organisms or of a specific nature from bacteria from Chlamydiales (o)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811Peptides or proteins is immobilized on, or in, an inorganic carrier
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813Carrier is a saccharide
    • Y10S530/814Cellulose or derivatives thereof
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se revela una proteína HMW de especies de Chlamydia y los ácidos nucleicos, vectores de expresion recombinante, células huésped transformadas, proteínasrecombinantes, composiciones inmunogénicas y antigénicas, métodos para producir una respuesta inmune en animales, antisueros, anticuerpos reactivos y equiposde diagnostico, método de deteccion y diagnostico de anticuerpos, método de deteccion y diagnostico de Chlamydia, composiciones farmacéuticas y de vacuna,métodos terapéuticos y de afeccionesrelacionadas con Chlamydia y métodos de deteccion y de diagnostico de ácidos nucleicos asociados. Las Chlamydiaconstituyen patogenos humanos de frecuente ocurrencia, que causan trastornos, tales como enfermedades transmitidas sexualmente, enfermedades respiratorias,que incluyen la neumonía, la conjuntivitis neonatal, y la ceguera. Las Chlamydia son bacterias intracelulares obligadas que infectan el revestimiento interiorepitelial del pulmon, la conjuntiva o tracto genital. Las especies más comunes de Chlamydia incluyen, Chlamydia trachomatis, Chlamydia psittaci, Chlamydiapecorum y Chlamydia pneumoniae.Recientemente, las especies nuevamente designadas de Chlamydia, Chlamydia pneumoniae (anteriormente Chlamydia trachomatis TWAR),han sido implicadas como la mayor causa de neumonitis humana epidémica y tal vez puedan jugar un papel en la aterosclerosis.
ARP980104960A 1997-10-02 1998-10-05 Una proteina de alto peso molecular (hmw) aislada de especies de chlamydia y los acidos nucleicos, vectores de expresion recombinante, celulas huespedtransformadas, proteinas recombinantes, composiciones inmunogenicas y antigenicas, metodos para producir una respuesta inmune en animales, antisueros, AR018013A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/942,596 US7459524B1 (en) 1997-10-02 1997-10-02 Chlamydia protein, sequence and uses thereof

Publications (1)

Publication Number Publication Date
AR018013A1 true AR018013A1 (es) 2001-10-31

Family

ID=25478327

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP980104960A AR018013A1 (es) 1997-10-02 1998-10-05 Una proteina de alto peso molecular (hmw) aislada de especies de chlamydia y los acidos nucleicos, vectores de expresion recombinante, celulas huespedtransformadas, proteinas recombinantes, composiciones inmunogenicas y antigenicas, metodos para producir una respuesta inmune en animales, antisueros,
ARP080105319A AR069600A2 (es) 1997-10-02 2008-12-05 Composiciones que comprenden un polipeptido aislado, o un anticuerpo aislado o fragmento que se une al antigeno del mismo, y un vehiculo, los vectores de expresion, las celulas hospedantes, los reactivos de diagnostico, los metodos para detectar chlamydia, anticuerpos anti-chlamydia y acidos nucleic

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP080105319A AR069600A2 (es) 1997-10-02 2008-12-05 Composiciones que comprenden un polipeptido aislado, o un anticuerpo aislado o fragmento que se une al antigeno del mismo, y un vehiculo, los vectores de expresion, las celulas hospedantes, los reactivos de diagnostico, los metodos para detectar chlamydia, anticuerpos anti-chlamydia y acidos nucleic

Country Status (16)

Country Link
US (6) US7459524B1 (es)
EP (2) EP1019028A4 (es)
JP (1) JP2001518489A (es)
KR (1) KR100586569B1 (es)
CN (2) CN1268637C (es)
AR (2) AR018013A1 (es)
AU (1) AU752426B2 (es)
BR (1) BR9813841A (es)
CA (1) CA2305709A1 (es)
CO (1) CO5050400A1 (es)
HK (1) HK1034187A1 (es)
HU (1) HUP0004639A3 (es)
NZ (1) NZ503763A (es)
SA (1) SA99191283B1 (es)
WO (1) WO1999017741A1 (es)
ZA (1) ZA989012B (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6710033B1 (en) 1996-08-14 2004-03-23 Vanderbilt University Methods and treatment of multiple sclerosis
US5868735A (en) 1997-03-06 1999-02-09 Scimed Life Systems, Inc. Cryoplasty device and method
US6890526B2 (en) 1997-05-06 2005-05-10 Vanderbilt University Methods and reagents for the treatment of multiple sclerosis
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
WO2000034498A1 (en) * 1998-12-04 2000-06-15 University Of Manitoba Two-step immunization procedure against chlamydia infection
US20020061848A1 (en) 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US20080213264A1 (en) * 1998-12-08 2008-09-04 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
DE60036698T2 (de) * 1999-05-03 2008-07-24 Sanofi Pasteur Ltd., Toronto Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen
DE60133190T2 (de) 2000-04-21 2009-04-02 CORIXA CORP., Wilmington Verbindungen und verfahren zur behandlung und diagnose von chlamydia-infektionen
US6919187B2 (en) * 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US7731980B2 (en) * 2000-10-02 2010-06-08 Emergent Product Development Gaithersburg Inc. Chlamydia PMP proteins, gene sequences and uses thereof
US7537772B1 (en) 2000-10-02 2009-05-26 Emergent Product Development Gaithersburg Inc. Chlamydia protein, gene sequence and the uses thereof
GB0109297D0 (en) 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
ES2386386T3 (es) * 2001-12-12 2012-08-20 Novartis Vaccines And Diagnostics S.R.L. Inmunización contra Chlamydia trachomatis
US7807802B2 (en) 2002-11-12 2010-10-05 Abbott Lab Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae
ITTO20050905A1 (it) * 2005-12-23 2007-06-24 Univ Degli Studi Torino Leganti sintetici capaci di legare l'ocratossina e relativi usi
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
TR201807756T4 (tr) 2006-09-26 2018-06-21 Infectious Disease Res Inst Sentetik adjuvan içeren aşı bileşimi.
PT2086582E (pt) 2006-10-12 2013-01-25 Glaxosmithkline Biolog Sa Vacina compreendendo uma emulsão adjuvante óleo em água
SI2086582T1 (sl) 2006-10-12 2013-02-28 Glaxosmithkline Biologicals S.A. Cepivo, ki obsega emulzijo olja v vodi kot adjuvans
TW200908994A (en) 2007-04-20 2009-03-01 Glaxosmithkline Biolog Sa Vaccine
EP2162460A4 (en) * 2007-06-14 2012-06-06 Emergent Product Dev Gaithersburg Inc VACCINES AGAINST CHLAMYDIA INFECTIONS
US20090254588A1 (en) * 2007-06-19 2009-10-08 Zhong Li Multi-Dimensional Data Merge
WO2009158240A1 (en) * 2008-06-16 2009-12-30 Emergent Product Development Uk Limited Salmonella vectored vaccines against chlamydia and methods of use
WO2010005474A1 (en) * 2008-06-16 2010-01-14 Emergent Product Development Gaithersburg Inc. Recombinant modified vaccinia virus ankara (mva) expressing chlamydia polypeptide antigens
EP2413959A4 (en) 2009-01-29 2013-06-19 British Columbia Cancer Agency CHLAMYDIA-ANTIGENE COMPREHENSIVE COMPOSITIONS
EP2437753B1 (en) 2009-06-05 2016-08-31 Infectious Disease Research Institute Synthetic glucopyranosyl lipid adjuvants and vaccine compositions containing them
ES2651005T3 (es) 2010-03-09 2018-01-23 Biomedical Research Models, Inc. Una nueva estrategia de vacunación mucosa para el virus del herpes simple tipo-2
AU2012243039B2 (en) 2011-04-08 2017-07-13 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
CN104363892A (zh) 2012-02-07 2015-02-18 传染性疾病研究院 包含tlr4激动剂的改进佐剂制剂及其使用方法
RS57420B1 (sr) 2012-05-16 2018-09-28 Immune Design Corp Vakcine za hsv-2
AU2014203873A1 (en) 2013-01-07 2015-07-30 Biomedical Research Models, Inc. Therapeutic vaccines for treating herpes simplex virus type 2 infections
CA2909221A1 (en) 2013-04-18 2014-10-23 Immune Design Corp. Gla monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
US11801223B2 (en) 2013-12-31 2023-10-31 Access To Advanced Health Institute Single vial vaccine formulations
WO2017176076A1 (en) 2016-04-06 2017-10-12 Ewha University - Industry Collaboration Foundation A peptide with ability to penetrate cell membrane
CN109562057A (zh) 2016-05-16 2019-04-02 传染病研究所 聚乙二醇化脂质体和使用方法
IL314130A (en) 2016-05-16 2024-09-01 Access To Advanced Health Inst Formulation containing a TLR agonist and methods of use
BR112018074352B1 (pt) 2016-06-01 2021-11-30 Infectious Disease Research Institute Partículas de nanoalume contendo um agente de dimensionamento
KR102673794B1 (ko) 2017-06-15 2024-06-11 액세스 투 어드밴스드 헬스 인스티튜트 나노구조 지질 담체 및 안정적인 에멀션 그리고 이들의 용도
CN111315406A (zh) 2017-09-08 2020-06-19 传染病研究所 包括皂苷的脂质体调配物及其使用方法
CN114340665A (zh) 2019-05-25 2022-04-12 传染病研究所 用于对佐剂疫苗乳剂进行喷雾干燥的组合物和方法
AU2021337493A1 (en) 2020-09-04 2023-05-18 Access To Advanced Health Institute Co-lyophilized rna and nanostructured lipid carrier
WO2024052882A1 (en) 2022-09-09 2024-03-14 Access To Advanced Health Institute Immunogenic vaccine composition incorporating a saponin

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258029A (en) 1979-04-23 1981-03-24 Connaught Laboratories Limited Synthetic adjuvants for stimulation of antigenic responses
US4427782A (en) * 1981-03-03 1984-01-24 Caldwell Harlan D Isolation of principal outer membrane protein and antigen of Chlamydia trachomatis
US4952496A (en) 1984-03-30 1990-08-28 Associated Universities, Inc. Cloning and expression of the gene for bacteriophage T7 RNA polymerase
DE3521994A1 (de) 1985-06-20 1987-01-02 Bayer Ag N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US4935352A (en) 1985-10-21 1990-06-19 Takeda Chemical Industries, Ltd. Expression vector for animal cell line and use thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
DE69018926T2 (de) 1989-09-04 1995-08-24 Wellcome Found Vakzine gegen Bordetella.
US5071962A (en) 1990-05-31 1991-12-10 The United State Of America As Represented By The Department Of Health And Human Services Nucleotide, deduced amino acid sequence, isolation and purification of heat-shock chlamydial proteins
US5965141A (en) 1991-02-15 1999-10-12 Uab Research Foundation Epitopic regions of pneumococcal surface protein a
US5725863A (en) * 1991-09-06 1998-03-10 The United States Of America As Represented By The Secretary Of Agriculture Polypeptides useful in prevention of chlamydia infection
ES2143716T3 (es) * 1992-06-25 2000-05-16 Smithkline Beecham Biolog Composicion de vacuna que contiene adyuvantes.
GB9214857D0 (en) 1992-07-13 1992-08-26 Medical Res Council Human nucleic acid fragments and their use
IL107628A0 (en) 1992-11-18 1994-02-27 Calypte Inc Immunoassays for microorganisms associated with sexually transmitted diseases
WO1995007353A2 (en) 1993-09-10 1995-03-16 The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services Binding domains from plasmodium vivax and plasmodium falciparum erythrocyte binding proteins
CN1134112A (zh) 1993-11-03 1996-10-23 辉瑞大药厂 衣原体感染的疫苗及治疗方法
US5565352A (en) 1993-11-24 1996-10-15 Arch Development Corporation Deubiquitinating enzyme: compositions and methods
DE69510116T2 (de) 1994-02-23 1999-11-18 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Nicht reduzierendes Saccharid bildendes Enzym, dieses kodierende DNA, und deren Herstellungen und Verwendungen
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US6019982A (en) * 1994-08-26 2000-02-01 The Administrators Of The Tulane Educational Fund Mutant enterotoxin effective as a non-toxic oral adjuvant
DE69628554T2 (de) 1995-03-28 2004-05-06 Hitachi Chemical Co., Ltd. Chlamydia-pneumoniae-antigen, verfahren zu seiner herstellung, verfahren zur testung von anti-chlamydia-pneumoniae-antikörper durch seine verwendung und reagenz zum testen von anti-chlamydia-pneumoniae-antikörper
GB9506863D0 (en) 1995-04-03 1995-05-24 Smithkline Beecham Biolog Vaccines
US5807978A (en) * 1995-06-07 1998-09-15 Kokolus; William J. Immunogenic peptides of prostate specific antigen
JPH09184843A (ja) * 1995-12-28 1997-07-15 Meiji Milk Prod Co Ltd クラミジア・トラコマチス感染の診断方法
US6464979B1 (en) 1996-09-12 2002-10-15 Aventis Pasteur Limited Chlamydial vaccines and methods of preparation thereof
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
KR100769103B1 (ko) 1997-11-28 2007-10-23 세로노 제네틱스 인스티튜트 에스.에이. 클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도
ES2330903T3 (es) 1997-12-17 2009-12-16 Serono Genetics Institute S.A. Adncs extendidos para proteinas secretadas.
US6077693A (en) * 1998-05-14 2000-06-20 Incyte Pharmaceuticals, Inc. Polynucleotide encoding a promonocyte associated protein
US20020061848A1 (en) 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
KR20100132086A (ko) 1998-12-08 2010-12-16 코릭사 코포레이션 클라미디아 감염을 치료 및 진단하기 위한 조성물 및 이를 포함하는 약제학적 조성물 및 진단 키트
US6565856B1 (en) 1998-12-08 2003-05-20 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US7731980B2 (en) 2000-10-02 2010-06-08 Emergent Product Development Gaithersburg Inc. Chlamydia PMP proteins, gene sequences and uses thereof
GB0103169D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
EP2162460A4 (en) 2007-06-14 2012-06-06 Emergent Product Dev Gaithersburg Inc VACCINES AGAINST CHLAMYDIA INFECTIONS
JP4743455B2 (ja) 2009-05-26 2011-08-10 トヨタ自動車株式会社 燃料電池システム

Also Published As

Publication number Publication date
CA2305709A1 (en) 1999-04-15
NZ503763A (en) 2003-01-31
US20040067524A1 (en) 2004-04-08
EP1019028A4 (en) 2002-11-20
EP1019028A1 (en) 2000-07-19
US7459524B1 (en) 2008-12-02
CO5050400A1 (es) 2001-06-27
HUP0004639A3 (en) 2004-10-28
US7419807B2 (en) 2008-09-02
KR100586569B1 (ko) 2006-06-02
EP1862472A3 (en) 2008-03-19
US7534445B2 (en) 2009-05-19
JP2001518489A (ja) 2001-10-16
AU752426B2 (en) 2002-09-19
US20050048557A1 (en) 2005-03-03
HUP0004639A2 (hu) 2001-04-28
HK1034187A1 (en) 2001-10-19
ZA989012B (en) 1999-04-12
BR9813841A (pt) 2000-10-03
CN1911960B (zh) 2012-11-07
SA99191283B1 (ar) 2006-04-18
US6642023B1 (en) 2003-11-04
KR20010030902A (ko) 2001-04-16
US7655246B2 (en) 2010-02-02
EP1862472A2 (en) 2007-12-05
WO1999017741A1 (en) 1999-04-15
CN1268637C (zh) 2006-08-09
US20040137005A1 (en) 2004-07-15
AR069600A2 (es) 2010-02-03
CN1283108A (zh) 2001-02-07
US6887843B1 (en) 2005-05-03
AU9598898A (en) 1999-04-27
CN1911960A (zh) 2007-02-14

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