AR016726A1 - Procedimiento para purificar esteres de carbazol precursores del acido 6-cloro-alfa-metilcarbazol-2-acetico - Google Patents

Procedimiento para purificar esteres de carbazol precursores del acido 6-cloro-alfa-metilcarbazol-2-acetico

Info

Publication number
AR016726A1
AR016726A1 ARP990102821A ARP990102821A AR016726A1 AR 016726 A1 AR016726 A1 AR 016726A1 AR P990102821 A ARP990102821 A AR P990102821A AR P990102821 A ARP990102821 A AR P990102821A AR 016726 A1 AR016726 A1 AR 016726A1
Authority
AR
Argentina
Prior art keywords
purifying
methylarbazol
carbazol
chlorine
acetic
Prior art date
Application number
ARP990102821A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR016726A1 publication Critical patent/AR016726A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/84—Separation, e.g. from tar; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un procedimiento para purificar un éster de di(alquilo C1-6) del ácido (6-cloro-2-carbazolil)metilmalonico de la formula (I) en la que Ra y Rb deben seriguales y se seleccionan del grupo formado por alquilo C1-6, comprende separar, por separacion defase, del citado éster de cabazol una o más impurezas por lomenos una vez, en el que el disolvente usado para realizar la citada separacion de fases es ácido acético. En una realizacion preferida, el citado ácidoacético galcial que se mantiene a unatemperatura de aproximadamente 30 a aproximadamente 110sC y el cita éster de carbazol se obtiene con una pureza de por lomenos 99,90% en peso por lo que la cantidad de impurezas presentes en él es 0,10% en peso o menos. En una realizacion más preferida del citado procedimiento,la citada temperatura es de aproximadamente 50 a aproximadamente 70SC y la citada separacion de fases se realiza solo una vez.
ARP990102821A 1998-06-16 1999-06-11 Procedimiento para purificar esteres de carbazol precursores del acido 6-cloro-alfa-metilcarbazol-2-acetico AR016726A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8948098P 1998-06-16 1998-06-16

Publications (1)

Publication Number Publication Date
AR016726A1 true AR016726A1 (es) 2001-07-25

Family

ID=22217887

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990102821A AR016726A1 (es) 1998-06-16 1999-06-11 Procedimiento para purificar esteres de carbazol precursores del acido 6-cloro-alfa-metilcarbazol-2-acetico

Country Status (26)

Country Link
US (1) US6013808A (es)
EP (1) EP0965586B1 (es)
JP (1) JP3449602B2 (es)
KR (1) KR100342148B1 (es)
CN (1) CN1119329C (es)
AR (1) AR016726A1 (es)
AT (1) ATE237588T1 (es)
AU (1) AU745058C (es)
BR (1) BR9902279A (es)
CA (1) CA2274355C (es)
CZ (1) CZ293399B6 (es)
DE (1) DE69906876T2 (es)
DK (1) DK0965586T3 (es)
ES (1) ES2196723T3 (es)
HK (1) HK1023999A1 (es)
HU (1) HUP9901989A3 (es)
ID (1) ID23297A (es)
IL (1) IL130428A (es)
PL (1) PL333741A1 (es)
PT (1) PT965586E (es)
RU (1) RU2182148C2 (es)
SG (1) SG76627A1 (es)
TR (1) TR199901330A2 (es)
TW (1) TW491839B (es)
YU (1) YU26999A (es)
ZA (1) ZA993974B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020049283A (ko) * 2000-12-19 2002-06-26 이계안 하이브리드 전기 자동차용 토크 제어 시동방법
JP4467880B2 (ja) 2002-12-09 2010-05-26 株式会社日立製作所 プロジェクトの評価システムおよび方法
TWI692598B (zh) 2019-05-03 2020-05-01 愛烙達股份有限公司 可變形之燭芯及設置該燭芯之燃燒裝置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193923A (en) * 1978-08-21 1980-03-18 Hoffmann-La Roche Inc. Tetrahydro 2-carbazolyl methyl malonate derivatives
CH637117A5 (de) * 1979-03-02 1983-07-15 Hoffmann La Roche Verfahren zur herstellung eines carbazolderivates.
JPS62263153A (ja) * 1986-05-28 1987-11-16 エフ・ホフマン―ラ　ロシユ　アーゲー カルバゾ−ル誘導体
DE3814887C1 (es) * 1988-05-02 1989-09-21 Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De

Also Published As

Publication number Publication date
KR20000006168A (ko) 2000-01-25
ZA993974B (en) 2000-12-15
RU2182148C2 (ru) 2002-05-10
BR9902279A (pt) 2000-02-29
SG76627A1 (en) 2000-11-21
ID23297A (id) 2000-04-05
ATE237588T1 (de) 2003-05-15
AU745058B2 (en) 2002-03-07
DE69906876T2 (de) 2003-12-24
TR199901330A2 (xx) 2000-01-21
HUP9901989A3 (en) 2001-01-29
EP0965586B1 (en) 2003-04-16
IL130428A0 (en) 2000-06-01
HUP9901989A2 (hu) 2000-03-28
CN1242362A (zh) 2000-01-26
HK1023999A1 (en) 2000-09-29
CZ214299A3 (cs) 2000-04-12
US6013808A (en) 2000-01-11
KR100342148B1 (ko) 2002-06-27
YU26999A (sh) 2002-12-10
PT965586E (pt) 2003-06-30
JP2000007656A (ja) 2000-01-11
ES2196723T3 (es) 2003-12-16
EP0965586A1 (en) 1999-12-22
PL333741A1 (en) 1999-12-20
TW491839B (en) 2002-06-21
CA2274355A1 (en) 1999-12-16
DE69906876D1 (de) 2003-05-22
HU9901989D0 (en) 1999-08-30
IL130428A (en) 2003-12-10
CA2274355C (en) 2004-08-10
AU745058C (en) 2002-11-07
CN1119329C (zh) 2003-08-27
JP3449602B2 (ja) 2003-09-22
CZ293399B6 (cs) 2004-04-14
AU3503899A (en) 1999-12-23
DK0965586T3 (da) 2003-08-04

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