AP3576A - Inhibitors of flaviviridae viruses - Google Patents

Inhibitors of flaviviridae viruses

Info

Publication number
AP3576A
AP3576A AP2012006414A AP2012006414A AP3576A AP 3576 A AP3576 A AP 3576A AP 2012006414 A AP2012006414 A AP 2012006414A AP 2012006414 A AP2012006414 A AP 2012006414A AP 3576 A AP3576 A AP 3576A
Authority
AP
ARIPO
Prior art keywords
inhibitors
flaviviridae viruses
flaviviridae
viruses
Prior art date
Application number
AP2012006414A
Other languages
English (en)
Other versions
AP2012006414A0 (en
Inventor
Eda Canales
Michael O'neil Hanrahan Clarke
Scott E Lazerwith
Willard Lew
Philip Anthony Morganelli
William J Watkins
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43538203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3576(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of AP2012006414A0 publication Critical patent/AP2012006414A0/xx
Application granted granted Critical
Publication of AP3576A publication Critical patent/AP3576A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AP2012006414A 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses AP3576A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29557610P 2010-01-15 2010-01-15
US35348110P 2010-06-10 2010-06-10
PCT/US2011/021335 WO2011088345A1 (en) 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses

Publications (2)

Publication Number Publication Date
AP2012006414A0 AP2012006414A0 (en) 2012-08-31
AP3576A true AP3576A (en) 2016-02-08

Family

ID=43538203

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2012006414A AP3576A (en) 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses

Country Status (27)

Country Link
US (2) US8513298B2 (enExample)
EP (2) EP2523950B1 (enExample)
JP (2) JP5868872B2 (enExample)
KR (1) KR101727776B1 (enExample)
CN (1) CN102712633B (enExample)
AP (1) AP3576A (enExample)
AR (1) AR080001A1 (enExample)
AU (1) AU2011205744B2 (enExample)
BR (1) BR112012017382A2 (enExample)
CA (1) CA2785567C (enExample)
CL (1) CL2012001960A1 (enExample)
CR (1) CR20120417A (enExample)
EA (1) EA021196B1 (enExample)
EC (1) ECSP12012104A (enExample)
ES (1) ES2626150T3 (enExample)
IL (1) IL220545B (enExample)
MX (1) MX2012008211A (enExample)
NZ (1) NZ600817A (enExample)
PE (1) PE20130281A1 (enExample)
PL (1) PL2523950T3 (enExample)
PT (1) PT2523950T (enExample)
SG (2) SG10201500298PA (enExample)
SI (1) SI2523950T1 (enExample)
TW (1) TWI491609B (enExample)
UY (1) UY33183A (enExample)
WO (1) WO2011088345A1 (enExample)
ZA (1) ZA201205248B (enExample)

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AU2010276441B2 (en) * 2009-07-21 2015-07-02 Gilead Sciences, Inc. Inhibitors of Flaviviridae viruses
EP2507249B1 (en) 2009-09-09 2015-11-11 Gilead Sciences, Inc. Inhibitors of flaviviridae viruses
AU2011205744B2 (en) 2010-01-15 2015-06-25 Gilead Sciences, Inc. Inhibitors of Flaviviridae viruses
PT2523951E (pt) * 2010-01-15 2015-09-14 Gilead Sciences Inc Inibidores de vírus flaviviridae
WO2012087596A1 (en) * 2010-12-20 2012-06-28 Gilead Sciences, Inc. Combinations for treating hcv
DE102011003295A1 (de) * 2011-01-28 2012-08-02 Kiekert Ag Kraftfahrzeugschloss
EP2734515B1 (en) * 2011-07-13 2015-11-04 Gilead Sciences, Inc. Thiophen-2-carboxylic acid derivatives useful as inhibitors of flaviviridae viruses
AU2012308295B2 (en) * 2011-09-16 2017-10-26 Gilead Sciences, Inc. Methods for treating HCV
CN103087052A (zh) * 2011-10-31 2013-05-08 上海壹志医药科技有限公司 噻吩衍生物及其药物用途
CA2875718A1 (en) 2012-06-08 2013-12-12 Selcia Limited Macrocyclic inhibitors of flaviviridae viruses
NZ724503A (en) 2012-06-08 2017-12-22 Gilead Sciences Inc Macrocyclic inhibitors of flaviviridae viruses
AR091279A1 (es) 2012-06-08 2015-01-21 Gilead Sciences Inc Inhibidores macrociclicos de virus flaviviridae
US8759544B2 (en) 2012-08-17 2014-06-24 Gilead Sciences, Inc. Synthesis of an antiviral compound
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CN107074904B (zh) 2014-10-23 2022-12-23 深圳华大智造科技股份有限公司 信号约束测序(scs)和用于信号约束测序的核苷酸类似物
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FI3706762T3 (fi) 2017-12-07 2024-12-13 Univ Emory N4-hydroksisytidiini ja johdannaisia sekä niihin liittyviä virusten vastaisia käyttötapoja
CN108096562B (zh) * 2017-12-25 2021-05-11 武汉百药联科科技有限公司 20s蛋白酶体抑制剂在制备治疗日本乙型脑炎病毒感染的药物中的用途
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Also Published As

Publication number Publication date
JP5868872B2 (ja) 2016-02-24
ES2626150T3 (es) 2017-07-24
AU2011205744A1 (en) 2012-07-26
PE20130281A1 (es) 2013-03-08
AU2011205744B2 (en) 2015-06-25
EA201290576A1 (ru) 2013-01-30
CR20120417A (es) 2012-11-30
CA2785567C (en) 2018-03-27
US20110178129A1 (en) 2011-07-21
CN102712633A (zh) 2012-10-03
NZ600817A (en) 2014-08-29
TW201134822A (en) 2011-10-16
BR112012017382A2 (pt) 2017-12-05
US8513298B2 (en) 2013-08-20
US20130315861A1 (en) 2013-11-28
PL2523950T3 (pl) 2017-09-29
WO2011088345A1 (en) 2011-07-21
SG182475A1 (en) 2012-08-30
IL220545A0 (en) 2012-08-30
SG10201500298PA (en) 2015-03-30
AP2012006414A0 (en) 2012-08-31
TWI491609B (zh) 2015-07-11
UY33183A (es) 2011-08-31
ZA201205248B (en) 2013-03-27
CN102712633B (zh) 2015-07-29
CA2785567A1 (en) 2011-07-21
KR20120101733A (ko) 2012-09-14
SI2523950T1 (sl) 2017-06-30
AR080001A1 (es) 2012-03-07
EP2523950A1 (en) 2012-11-21
KR101727776B1 (ko) 2017-04-17
PT2523950T (pt) 2017-06-01
CL2012001960A1 (es) 2012-10-26
US9321753B2 (en) 2016-04-26
EA021196B1 (ru) 2015-04-30
EP2523950B1 (en) 2017-03-15
JP2016041732A (ja) 2016-03-31
ECSP12012104A (es) 2012-09-28
JP2013517291A (ja) 2013-05-16
IL220545B (en) 2018-02-28
EP3219713A1 (en) 2017-09-20
MX2012008211A (es) 2012-08-08

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