AP231A - Antimalarial composition. - Google Patents
Antimalarial composition. Download PDFInfo
- Publication number
- AP231A AP231A APAP/P/1991/000275A AP9100275A AP231A AP 231 A AP231 A AP 231A AP 9100275 A AP9100275 A AP 9100275A AP 231 A AP231 A AP 231A
- Authority
- AP
- ARIPO
- Prior art keywords
- effective amount
- pharmaceutical composition
- benflumetol
- artemether
- compound
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 31
- 239000003430 antimalarial agent Substances 0.000 title abstract description 16
- 230000000078 anti-malarial effect Effects 0.000 title description 13
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- SXYIRMFQILZOAM-HVNFFKDJSA-N dihydroartemisinin methyl ether Chemical compound C1C[C@H]2[C@H](C)CC[C@H]3[C@@H](C)[C@@H](OC)O[C@H]4[C@]32OO[C@@]1(C)O4 SXYIRMFQILZOAM-HVNFFKDJSA-N 0.000 claims abstract description 30
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN90106722A CN1058717A (zh) | 1990-08-08 | 1990-08-08 | 抗疟新药—复方蒿甲醚及其制备方法 |
| CN91102575A CN1085527C (zh) | 1990-08-08 | 1991-04-24 | 增效复方抗疟药本芴醇的制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9100275A0 AP9100275A0 (en) | 1991-07-31 |
| AP231A true AP231A (en) | 1993-01-31 |
Family
ID=25742651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1991/000275A AP231A (en) | 1990-08-08 | 1991-06-12 | Antimalarial composition. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5677331A (fr) |
| EP (1) | EP0500823B1 (fr) |
| JP (1) | JP2562857B2 (fr) |
| KR (1) | KR100221689B1 (fr) |
| CN (2) | CN1058717A (fr) |
| AP (1) | AP231A (fr) |
| AT (1) | ATE135209T1 (fr) |
| AU (1) | AU642747B2 (fr) |
| CA (1) | CA2065285C (fr) |
| DE (2) | DE69117922T2 (fr) |
| DK (1) | DK0500823T3 (fr) |
| EG (1) | EG19905A (fr) |
| ES (1) | ES2084168T3 (fr) |
| FI (1) | FI921491L (fr) |
| GR (1) | GR3019313T3 (fr) |
| HU (1) | HU227345B1 (fr) |
| IE (1) | IE72095B1 (fr) |
| IL (1) | IL98463A (fr) |
| LU (1) | LU90844I2 (fr) |
| MA (1) | MA22176A1 (fr) |
| NL (1) | NL300048I2 (fr) |
| NZ (1) | NZ238477A (fr) |
| PT (1) | PT97945B (fr) |
| SA (1) | SA91120263B1 (fr) |
| WO (1) | WO1992002217A1 (fr) |
| ZA (1) | ZA914490B (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5637594A (en) * | 1991-04-11 | 1997-06-10 | Ciba Geigy Corporation | Antimalarial synergistic compositions containing benflumetol |
| HU220605B1 (hu) * | 1992-02-07 | 2002-03-28 | Novartis Ag. | Eljárás benflumetol-tartalmú maláriaellenes szinergetikus gyógyászati készítmények előállítására |
| WO1995027964A1 (fr) * | 1994-04-12 | 1995-10-19 | Qualcomm Incorporated | Procede et dispositif de transport de fret au moyen d'un systeme de navigation par satellite |
| US5657088A (en) * | 1995-12-22 | 1997-08-12 | Cirrus Logic, Inc. | System and method for extracting caption teletext information from a video signal |
| US6136847A (en) * | 1996-12-02 | 2000-10-24 | Johns Hopkins University | Water-soluble trioxanes as potent and safe antimalarial agents |
| CH692321A5 (de) | 1997-11-03 | 2002-05-15 | Mepha Ag | Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält. |
| CO5040050A1 (es) * | 1998-06-25 | 2001-05-29 | Novartis Ag | Compuestos de 2-amino-1-(9-arilmetilidina-2,7-dicloro-9h- fluoren-4-ilo)-etanoles n-sustituidos, procedimientos para su obtencion y preparados farmaceuticos que los contienen . |
| IN191696B (fr) * | 1999-02-12 | 2003-12-20 | Council Scient Ind Res | |
| EP1267864A1 (fr) * | 2000-03-31 | 2003-01-02 | Council Of Scientific & Industrial Research | Formulation synergetique anti-paludique |
| US20040038933A1 (en) * | 2000-10-20 | 2004-02-26 | Yutaro Kaneko | Pharmaceutical compositions, dose and method for treating malaria |
| US7842719B2 (en) * | 2002-10-31 | 2010-11-30 | Kemin Foods, L.C. | Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus |
| WO2004075817A2 (fr) * | 2003-02-26 | 2004-09-10 | Vrije Universiteit Brussel | Composition pharmaceutique pouvant etre mise en suspension |
| BRPI0413767A (pt) * | 2003-09-04 | 2006-10-31 | Cipla Ltd | produto farmacêutico ou formulação farmacêutica, processo para preparar um produto farmacêutico ou formulação farmacêutica, método para tratar um doença e uso de pelo menos uma artemisinina ou um sal, solvato ou derivado desta |
| US20110206636A1 (en) * | 2003-09-16 | 2011-08-25 | Kemin Foods, LLC | Use of Endoperoxides for the Treatment of Infections Caused by Flaviviridae, Including Hepatitis C, Bovine Viral Diarrhea and Classical Swine Fever Virus |
| WO2007017646A2 (fr) * | 2005-08-05 | 2007-02-15 | Cipla Limited | Composition antimalarienne |
| WO2007036947A1 (fr) * | 2005-09-30 | 2007-04-05 | Ipca Laboratories Limited | Composition anti-paludéenne à libération retardée |
| WO2008001294A2 (fr) * | 2006-06-26 | 2008-01-03 | Ranbaxy Laboratories Limited | Compositions pharmaceutiques pour l'administration orale à des doses élévées d'arteméther et de luméfantrine |
| CN100463669C (zh) * | 2006-08-31 | 2009-02-25 | 广州市医药工业研究所 | 复方蒿甲醚自乳化剂 |
| WO2008098586A1 (fr) * | 2007-02-13 | 2008-08-21 | Dafra Pharma N.V. | Composition de support pharmaceutique et composition pharmaceutique |
| CH700941B1 (de) * | 2007-12-04 | 2010-11-15 | Mepha Ag | Pharmazeutische Zusammensetzung zur Behandlung von Malaria. |
| FR2926993B1 (fr) * | 2008-02-06 | 2011-03-11 | Sanofi Aventis | Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artemisinine ou l'un de ses derives pour le traitement du paludisme |
| WO2010004573A1 (fr) * | 2008-07-07 | 2010-01-14 | Ipca Laboratories Limited | Composition pharmaceutique synergiste antipaludique |
| JP6166346B2 (ja) * | 2012-03-30 | 2017-07-19 | ズートツッカー アクチェンゲゼルシャフト マンハイム／オクセンフルト | チューインガムコア材料の表面に塗布するための改良された圧延化合物粉末 |
| CN103251584A (zh) * | 2013-05-09 | 2013-08-21 | 西安力邦制药有限公司 | 注射用蒿甲醚/本芴醇复方脂肪乳的制备及其在疟疾治疗中的应用 |
| WO2015140709A1 (fr) * | 2014-03-19 | 2015-09-24 | Novartis Ag | Formes posologiques pharmaceutiques solides |
| KR20190139291A (ko) * | 2017-04-24 | 2019-12-17 | 노파르티스 아게 | 2-아미노-l-(2-(4-플루오로페닐)-3-(4-플루오로페닐아미노)-8,8-디메틸-5,6-디하이드로이미다조[1,2-a]피라진-7(8h)-일)에타논 및 이의 조합물의 치료 요법 |
| CN113599382B (zh) * | 2021-08-20 | 2023-01-03 | 兰州大学 | 喹啉类衍生物在制备治疗糖尿病及其并发症药物中的应用 |
| CN116410197A (zh) * | 2023-03-03 | 2023-07-11 | 五邑大学 | 一种喹啉环内过氧桥环衍生物及其制备方法 |
| CN116747218B (zh) * | 2023-08-21 | 2023-10-31 | 山东省中医药研究院 | 百秋李醇、百秋李醇复合抗疟组合物及制备抗疟原虫药物中的应用 |
| LU506390B1 (en) | 2024-02-09 | 2025-08-11 | L2R Sas | Oil-in-water jellified emulsion for use in anti-malarial treatment |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0362810A1 (fr) * | 1988-10-07 | 1990-04-11 | Hoechst Aktiengesellschaft | Compositions contre la malaria et méthodes de traitement utilisant la quinidine, artémisinine ou leurs dérivés |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85100781B (zh) * | 1985-04-01 | 1988-07-06 | 广西壮族自治区桂林制药厂 | 抗疟药物青蒿酯的制备方法 |
| CN85100978A (zh) * | 1985-04-01 | 1986-08-13 | 中医研究院中药研究所 | 还原青蒿素的生产工艺 |
| CN87101346A (zh) * | 1987-06-09 | 1988-03-09 | 山东省中医药研究所 | 青蒿素提取工艺 |
| CN1029680C (zh) * | 1988-11-10 | 1995-09-06 | 军事医学科学院微生物流行病研究所 | 抗疟新药苯芴醇的合成新工艺 |
-
1990
- 1990-08-08 CN CN90106722A patent/CN1058717A/zh not_active Withdrawn
-
1991
- 1991-04-24 CN CN91102575A patent/CN1085527C/zh not_active Expired - Lifetime
- 1991-06-05 DK DK91911449.6T patent/DK0500823T3/da active
- 1991-06-05 DE DE69117922T patent/DE69117922T2/de not_active Expired - Lifetime
- 1991-06-05 HU HU9201528A patent/HU227345B1/hu unknown
- 1991-06-05 DE DE2001199038 patent/DE10199038I2/de active Active
- 1991-06-05 WO PCT/EP1991/001033 patent/WO1992002217A1/fr not_active Ceased
- 1991-06-05 EP EP91911449A patent/EP0500823B1/fr not_active Expired - Lifetime
- 1991-06-05 JP JP3510033A patent/JP2562857B2/ja not_active Expired - Lifetime
- 1991-06-05 FI FI921491A patent/FI921491L/fi unknown
- 1991-06-05 KR KR1019920700800A patent/KR100221689B1/ko not_active Expired - Lifetime
- 1991-06-05 ES ES91911449T patent/ES2084168T3/es not_active Expired - Lifetime
- 1991-06-05 AU AU79549/91A patent/AU642747B2/en not_active Expired
- 1991-06-05 AT AT91911449T patent/ATE135209T1/de not_active IP Right Cessation
- 1991-06-05 CA CA002065285A patent/CA2065285C/fr not_active Expired - Lifetime
- 1991-06-10 MA MA22451A patent/MA22176A1/fr unknown
- 1991-06-11 EG EG35991A patent/EG19905A/xx active
- 1991-06-11 NZ NZ238477A patent/NZ238477A/xx not_active IP Right Cessation
- 1991-06-12 IE IE198991A patent/IE72095B1/en not_active IP Right Cessation
- 1991-06-12 IL IL9846391A patent/IL98463A/en not_active IP Right Cessation
- 1991-06-12 PT PT97945A patent/PT97945B/pt not_active IP Right Cessation
- 1991-06-12 ZA ZA914490A patent/ZA914490B/xx unknown
- 1991-06-12 AP APAP/P/1991/000275A patent/AP231A/en active
- 1991-12-10 SA SA91120263A patent/SA91120263B1/ar unknown
-
1994
- 1994-03-23 US US08/216,440 patent/US5677331A/en not_active Expired - Lifetime
-
1996
- 1996-03-14 GR GR960400492T patent/GR3019313T3/el unknown
-
2001
- 2001-07-19 LU LU90844C patent/LU90844I2/fr unknown
- 2001-07-19 NL NL300048C patent/NL300048I2/nl unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0362810A1 (fr) * | 1988-10-07 | 1990-04-11 | Hoechst Aktiengesellschaft | Compositions contre la malaria et méthodes de traitement utilisant la quinidine, artémisinine ou leurs dérivés |
Non-Patent Citations (1)
| Title |
|---|
| Parasitology 90, 1985, pp. 705-715, espec. 709-710 * |
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