AP1335A - Method for preparing substituted 4-phenyl-4-cyclohexanoic acids. - Google Patents
Method for preparing substituted 4-phenyl-4-cyclohexanoic acids. Download PDFInfo
- Publication number
- AP1335A AP1335A APAP/P/2000/001782A AP2000001782A AP1335A AP 1335 A AP1335 A AP 1335A AP 2000001782 A AP2000001782 A AP 2000001782A AP 1335 A AP1335 A AP 1335A
- Authority
- AP
- ARIPO
- Prior art keywords
- compound
- hydrogen
- alkyl
- water
- lithium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6161397P | 1997-10-10 | 1997-10-10 | |
PCT/US1998/021061 WO1999018793A1 (en) | 1997-10-10 | 1998-10-07 | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2000001782A0 AP2000001782A0 (en) | 2000-06-30 |
AP1335A true AP1335A (en) | 2004-11-29 |
Family
ID=22036929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/2000/001782A AP1335A (en) | 1997-10-10 | 1998-10-07 | Method for preparing substituted 4-phenyl-4-cyclohexanoic acids. |
Country Status (30)
Country | Link |
---|---|
EP (1) | EP1043930A4 (uk) |
JP (1) | JP2001519363A (uk) |
KR (1) | KR100560038B1 (uk) |
CN (1) | CN1192025C (uk) |
AP (1) | AP1335A (uk) |
AR (1) | AR015952A1 (uk) |
AU (1) | AU741832B2 (uk) |
BG (1) | BG104302A (uk) |
BR (1) | BR9814064A (uk) |
CA (1) | CA2305614A1 (uk) |
DZ (1) | DZ2619A1 (uk) |
EA (1) | EA003609B1 (uk) |
HU (1) | HUP0003905A3 (uk) |
ID (1) | ID25536A (uk) |
IL (1) | IL135434A (uk) |
MA (1) | MA24670A1 (uk) |
MY (1) | MY122105A (uk) |
NO (1) | NO20001777L (uk) |
NZ (1) | NZ503759A (uk) |
OA (1) | OA11347A (uk) |
PE (1) | PE121599A1 (uk) |
PL (1) | PL191974B1 (uk) |
SA (1) | SA99191000A (uk) |
SK (1) | SK4902000A3 (uk) |
TR (1) | TR200000945T2 (uk) |
TW (1) | TW440557B (uk) |
UA (1) | UA67753C2 (uk) |
UY (2) | UY25201A1 (uk) |
WO (1) | WO1999018793A1 (uk) |
ZA (1) | ZA989228B (uk) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9920152D0 (en) * | 1999-08-25 | 1999-10-27 | Smithkline Beecham Plc | Novel process |
WO2001043692A2 (en) * | 1999-12-15 | 2001-06-21 | Smithkline Beecham Corporation | SALTS OF Cis-4-CYANO-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]CYCLOHEXANE-1-CARBOXYLIC ACID |
AU3282201A (en) * | 2000-01-26 | 2001-08-07 | Smithkline Beecham Corporation | Monohydrate of CIS-lithium-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl) cyclohexanecarboxylate |
CA2402384A1 (en) | 2000-03-16 | 2001-09-20 | Inflazyme Pharmaceuticals Ltd. | Benzylated pde4 inhibitors |
BR0116852A (pt) | 2001-01-31 | 2004-02-25 | Pfizer Prod Inc | Derivados biarilados de nicotinamida úteis como inibidores de isozimas pde4 |
MXPA03006885A (es) | 2001-01-31 | 2003-11-13 | Pfizer Prod Inc | Derivados de eteres utiles como agentes inhibidores de las isozimas pde4. |
PL365443A1 (en) | 2001-01-31 | 2005-01-10 | Pfizer Products Inc. | Thiazolyl-, oxazolyl-, pyrrolyl-, and imidazolyl-acid amide derivatives useful as inhibitors of pde4 isozymes |
US7250518B2 (en) | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
CN102491959B (zh) * | 2011-12-19 | 2015-03-25 | 江苏澄扬作物科技有限公司 | 一种环氧乙烷衍生物的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5524438A (en) * | 1994-12-15 | 1996-06-11 | United Technologies Corporation | Segmented bulkhead liner for a gas turbine combustor |
US6452022B1 (en) * | 1997-10-10 | 2002-09-17 | Smithkline Beecham Corporation | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4021478A (en) * | 1972-07-13 | 1977-05-03 | The Upjohn Company | Preparation of carboxylic acids from glycidonitriles with ionic lewis acids |
MX9301943A (es) * | 1992-04-02 | 1994-08-31 | Smithkline Beecham Corp | Compuestos. |
MY118813A (en) * | 1997-02-12 | 2005-01-31 | Smithkline Beecham Corp | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
-
1998
- 1998-07-10 UA UA2000041944A patent/UA67753C2/uk unknown
- 1998-10-02 MA MA25278A patent/MA24670A1/fr unknown
- 1998-10-07 WO PCT/US1998/021061 patent/WO1999018793A1/en not_active Application Discontinuation
- 1998-10-07 UY UY25201A patent/UY25201A1/es not_active IP Right Cessation
- 1998-10-07 TR TR2000/00945T patent/TR200000945T2/xx unknown
- 1998-10-07 AR ARP980105002A patent/AR015952A1/es unknown
- 1998-10-07 ID IDW20000614A patent/ID25536A/id unknown
- 1998-10-07 CN CNB988100304A patent/CN1192025C/zh not_active Expired - Fee Related
- 1998-10-07 IL IL13543498A patent/IL135434A/en not_active IP Right Cessation
- 1998-10-07 CA CA002305614A patent/CA2305614A1/en not_active Abandoned
- 1998-10-07 HU HU0003905A patent/HUP0003905A3/hu not_active Application Discontinuation
- 1998-10-07 PL PL339759A patent/PL191974B1/pl not_active IP Right Cessation
- 1998-10-07 AU AU96874/98A patent/AU741832B2/en not_active Ceased
- 1998-10-07 JP JP2000515437A patent/JP2001519363A/ja active Pending
- 1998-10-07 KR KR1020007003742A patent/KR100560038B1/ko not_active IP Right Cessation
- 1998-10-07 EA EA200000406A patent/EA003609B1/ru not_active IP Right Cessation
- 1998-10-07 NZ NZ503759A patent/NZ503759A/en unknown
- 1998-10-07 EP EP98950965A patent/EP1043930A4/en not_active Withdrawn
- 1998-10-07 SK SK490-2000A patent/SK4902000A3/sk unknown
- 1998-10-07 AP APAP/P/2000/001782A patent/AP1335A/en active
- 1998-10-07 BR BR9814064-7A patent/BR9814064A/pt not_active IP Right Cessation
- 1998-10-07 DZ DZ980229A patent/DZ2619A1/xx active
- 1998-10-08 MY MYPI98004606A patent/MY122105A/en unknown
- 1998-10-09 ZA ZA989228A patent/ZA989228B/xx unknown
- 1998-10-09 PE PE1998000955A patent/PE121599A1/es not_active Application Discontinuation
- 1998-12-01 TW TW087116680A patent/TW440557B/zh not_active IP Right Cessation
-
1999
- 1999-01-26 SA SA99191000A patent/SA99191000A/ar unknown
- 1999-05-25 UY UY25524A patent/UY25524A1/es not_active Application Discontinuation
-
2000
- 2000-04-05 BG BG104302A patent/BG104302A/xx unknown
- 2000-04-06 NO NO20001777A patent/NO20001777L/no not_active Application Discontinuation
- 2000-04-07 OA OA1200000100A patent/OA11347A/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5524438A (en) * | 1994-12-15 | 1996-06-11 | United Technologies Corporation | Segmented bulkhead liner for a gas turbine combustor |
US6452022B1 (en) * | 1997-10-10 | 2002-09-17 | Smithkline Beecham Corporation | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP1335A (en) | Method for preparing substituted 4-phenyl-4-cyclohexanoic acids. | |
AP1215A (en) | Composition and methods for preparing substituted 4-phenyl-4- cynocyclohaxanic acids. | |
US6452022B1 (en) | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
MXPA00003405A (en) | Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
CZ20001273A3 (cs) | Způsob přípravy substituovaných 4-fenyl-4- kyancyklohexanových kyselin | |
EP1295869B1 (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
MXPA99007441A (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
EP1524268A1 (en) | Compounds and method for preparing sustituted 4-phenyl-4-cyanocyclohexanoic acids | |
NZ535657A (en) | Process and intermediates for preparing a cyclohexylnitrile | |
EP1246794A1 (en) | Process and intermediates for preparing a cyclohexylnitrile |