ZW31480A1 - Cyclohexene derivatives - Google Patents

Cyclohexene derivatives

Info

Publication number
ZW31480A1
ZW31480A1 ZW314/80A ZW31480A ZW31480A1 ZW 31480 A1 ZW31480 A1 ZW 31480A1 ZW 314/80 A ZW314/80 A ZW 314/80A ZW 31480 A ZW31480 A ZW 31480A ZW 31480 A1 ZW31480 A1 ZW 31480A1
Authority
ZW
Zimbabwe
Prior art keywords
cyclohexene derivatives
cyclohexene
derivatives
Prior art date
Application number
ZW314/80A
Other languages
English (en)
Inventor
Albert Eduard Fischli
Hans Bruderer
Rudolf Pfister
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZW31480A1 publication Critical patent/ZW31480A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
ZW314/80A 1980-01-29 1980-12-19 Cyclohexene derivatives ZW31480A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH72480A CH644580A5 (de) 1980-01-29 1980-01-29 Cyclohexen-derivate.

Publications (1)

Publication Number Publication Date
ZW31480A1 true ZW31480A1 (en) 1981-09-02

Family

ID=4193699

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW314/80A ZW31480A1 (en) 1980-01-29 1980-12-19 Cyclohexene derivatives

Country Status (32)

Country Link
US (2) US4336268A (it)
EP (1) EP0033156B1 (it)
JP (1) JPS56120650A (it)
KR (6) KR850000626B1 (it)
AR (1) AR227906A1 (it)
AT (2) ATE9895T1 (it)
AU (1) AU540697B2 (it)
BR (1) BR8100484A (it)
CA (1) CA1161064A (it)
CH (1) CH644580A5 (it)
CS (6) CS219940B2 (it)
DE (2) DE3102603A1 (it)
DK (1) DK15681A (it)
ES (6) ES8301200A1 (it)
FI (1) FI801147A (it)
FR (1) FR2479815A1 (it)
GB (1) GB2068373B (it)
HU (1) HU182280B (it)
IE (1) IE50885B1 (it)
IL (1) IL61961A (it)
IT (1) IT1135001B (it)
LU (1) LU83096A1 (it)
MC (1) MC1365A1 (it)
NL (1) NL8100403A (it)
NO (1) NO149958C (it)
NZ (1) NZ196086A (it)
PH (1) PH16098A (it)
PT (1) PT72415B (it)
SE (1) SE8100403L (it)
YU (1) YU332180A (it)
ZA (1) ZA81459B (it)
ZW (1) ZW31480A1 (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372919B1 (en) * 2001-01-11 2002-04-16 Dov Pharmaceutical, Inc. (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent
US6569887B2 (en) 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US20060173064A1 (en) * 2001-08-24 2006-08-03 Lippa Arnold S (-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders
US20080081834A1 (en) 2002-07-31 2008-04-03 Lippa Arnold S Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
US20060100263A1 (en) * 2004-11-05 2006-05-11 Anthony Basile Antipyretic compositions and methods
BRPI0613943B1 (pt) 2005-07-27 2021-06-22 Otsuka America Pharmaceutical, Inc Composto, composição farmacêutica o compreendendo, usos de um composto e de uma composição farmacêutica, bem como composição neurobiologicamente ativa
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) * 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US20080269348A1 (en) * 2006-11-07 2008-10-30 Phil Skolnick Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US20090069374A1 (en) * 2007-06-06 2009-03-12 Phil Skolnick Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes, Methods For Their Preparation And Their Use As Medicaments
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH249047A (de) * 1944-03-20 1947-05-31 Ag J R Geigy Verfahren zur Darstellung eines basischen Esters einer 1-Aryl-cycloalkyl-1-carbonsäure.
CH249052A (de) * 1944-03-20 1947-05-31 Ag J R Geigy Verfahren zur Darstellung eines basischen Amids einer 1-Aryl-cycloalkyl-1-carbonsäure.
US2647122A (en) * 1948-10-01 1953-07-28 Sterling Drug Inc Tertiary amines and process of preparing them
US3109845A (en) * 1960-02-04 1963-11-05 Thomae Gmbh Dr K 1-cyclohexyl, 1-cyclohexenyl, 1-furyl, and 1-thienyl, tertiary amino substituted methanes
DE1518545A1 (de) * 1965-04-01 1970-01-15 Boehringer Mannheim Gmbh Verfahren zur Herstellung neuer Phenylcyclohexylalkylamine und ihrer Salze
DE1518663A1 (de) * 1965-08-02 1969-12-18 Gruenenthal Chemie Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung
US3408396A (en) * 1965-10-22 1968-10-29 Colgate Palmolive Co alpha-cyclohexyl-3, 4-disubstituted-phenyl acetamides
US3485873A (en) * 1966-12-21 1969-12-23 Sterling Drug Inc N-benzyl-n-methyl-omega-phenyl-omega-cycloalkyl-lower-alkylamines
US3737451A (en) * 1970-09-23 1973-06-05 Sandoz Ag Cis-3,4-diaryl-cyclopentylidene-and 1-cyclopentene-1-acetic acids and derivatives
US4053637A (en) * 1971-06-11 1977-10-11 Astra Lakemedal Aktiebolag Compounds of diphenylcyclopentylamine type and methods for their uses
CA1130318A (en) * 1978-10-11 1982-08-24 Peter M. Muller Cyclohexadiene derivatives

Also Published As

Publication number Publication date
LU83096A1 (de) 1982-09-10
PT72415B (en) 1982-07-26
DK15681A (da) 1981-07-30
ES506686A0 (es) 1982-12-16
IE50885B1 (en) 1986-08-06
PT72415A (en) 1981-02-01
NL8100403A (nl) 1981-08-17
KR840001552B1 (ko) 1984-10-05
ES506684A0 (es) 1983-10-16
ATE9895T1 (de) 1984-11-15
PH16098A (en) 1983-06-24
FR2479815B1 (it) 1984-02-17
AU6671981A (en) 1981-08-06
GB2068373B (en) 1983-11-30
AU540697B2 (en) 1984-11-29
IT8119047A0 (it) 1981-01-08
CS219944B2 (en) 1983-03-25
EP0033156A2 (de) 1981-08-05
CS219941B2 (en) 1983-03-25
US4336268A (en) 1982-06-22
ES8400079A1 (es) 1983-10-16
CS219943B2 (en) 1983-03-25
NO149958C (no) 1984-07-25
MC1365A1 (fr) 1981-10-23
KR840001554B1 (ko) 1984-10-05
ES8301884A1 (es) 1982-12-16
DE3166656D1 (en) 1984-11-22
AR227906A1 (es) 1982-12-30
ES498866A0 (es) 1982-12-01
KR850000626B1 (ko) 1985-05-06
CS219942B2 (en) 1983-03-25
ES506688A0 (es) 1982-12-16
ES8301885A1 (es) 1982-12-16
ES506687A0 (es) 1982-12-16
IL61961A (en) 1984-05-31
KR840001553B1 (ko) 1984-10-05
KR850002003A (ko) 1985-04-10
FI801147A (fi) 1981-07-30
ES8301878A1 (es) 1982-12-16
ATA35581A (de) 1984-05-15
ES8301200A1 (es) 1982-12-01
NO149958B (no) 1984-04-16
ES8301883A1 (es) 1982-12-16
NO810297L (no) 1981-07-30
ES506685A0 (es) 1982-12-16
IE810153L (en) 1981-07-29
SE8100403L (sv) 1981-07-30
CH644580A5 (de) 1984-08-15
KR830005105A (ko) 1983-07-23
IL61961A0 (en) 1981-02-27
EP0033156B1 (de) 1984-10-17
YU332180A (en) 1983-10-31
US4448991A (en) 1984-05-15
GB2068373A (en) 1981-08-12
CS219940B2 (en) 1983-03-25
IT1135001B (it) 1986-08-20
KR850000627B1 (ko) 1985-05-06
ZA81459B (en) 1982-02-24
BR8100484A (pt) 1981-08-18
AT376654B (de) 1984-12-27
CA1161064A (en) 1984-01-24
NZ196086A (en) 1984-08-24
EP0033156A3 (en) 1982-03-17
CS220347B2 (en) 1983-03-25
KR840001551B1 (ko) 1984-10-05
HU182280B (en) 1983-12-28
FR2479815A1 (fr) 1981-10-09
JPS56120650A (en) 1981-09-22
DE3102603A1 (de) 1981-12-10

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