ZW1992A1 - 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol - Google Patents

4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Info

Publication number
ZW1992A1
ZW1992A1 ZW19/92A ZW1992A ZW1992A1 ZW 1992 A1 ZW1992 A1 ZW 1992A1 ZW 19/92 A ZW19/92 A ZW 19/92A ZW 1992 A ZW1992 A ZW 1992A ZW 1992 A1 ZW1992 A1 ZW 1992A1
Authority
ZW
Zimbabwe
Prior art keywords
difluorephenoxy
benzotiazolyl
methylamino
methyl
compound
Prior art date
Application number
ZW19/92A
Other languages
English (en)
Inventor
Antoine Stokbroekx Raymond
Arthur Jules Grauwels Gilbert
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZW1992A1 publication Critical patent/ZW1992A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Paper (AREA)
ZW19/92A 1991-02-25 1992-02-10 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol ZW1992A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65964591A 1991-02-25 1991-02-25

Publications (1)

Publication Number Publication Date
ZW1992A1 true ZW1992A1 (en) 1993-09-22

Family

ID=24646210

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW19/92A ZW1992A1 (en) 1991-02-25 1992-02-10 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Country Status (36)

Country Link
US (2) US5434168A (enExample)
EP (2) EP0573473B1 (enExample)
JP (1) JP2825652B2 (enExample)
KR (1) KR0165901B1 (enExample)
CN (3) CN1033454C (enExample)
AT (1) ATE131478T1 (enExample)
AU (1) AU649788B2 (enExample)
BG (1) BG62332B1 (enExample)
CA (1) CA2104000A1 (enExample)
CY (1) CY1924A (enExample)
CZ (1) CZ284705B6 (enExample)
DE (1) DE69206787T2 (enExample)
DK (1) DK0573473T3 (enExample)
DZ (1) DZ1560A1 (enExample)
EE (1) EE02983B1 (enExample)
ES (1) ES2083737T3 (enExample)
FI (1) FI933719A0 (enExample)
GR (1) GR3018692T3 (enExample)
HK (1) HK172296A (enExample)
HU (2) HUT67695A (enExample)
IE (1) IE69567B1 (enExample)
IL (3) IL100952A (enExample)
LV (1) LV11689B (enExample)
MA (1) MA22447A1 (enExample)
MX (1) MX9200777A (enExample)
NO (1) NO300591B1 (enExample)
NZ (2) NZ248437A (enExample)
PL (1) PL168791B1 (enExample)
RO (1) RO112959B1 (enExample)
RU (2) RU2094434C1 (enExample)
SK (1) SK278705B6 (enExample)
TN (1) TNSN92017A1 (enExample)
TW (1) TW218016B (enExample)
WO (1) WO1992014731A1 (enExample)
ZA (1) ZA921341B (enExample)
ZW (1) ZW1992A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol
TW282469B (enExample) * 1993-06-11 1996-08-01 Janssen Pharmaceutica Nv
MX9702506A (es) * 1994-10-14 1997-07-31 Janssen Pharmaceutica Nv Suspensiones orales de sabeluzol.
MX9703839A (es) * 1994-11-24 1997-08-30 Janssen Pharmaceutica Nv Soluciones intravenosas de lubeluzol.
WO1996032130A1 (en) * 1995-04-10 1996-10-17 Baxter International Inc. The use of cross-linked hemoglobin in treating subarachnoid hemorrhage
CN1200122A (zh) * 1995-10-25 1998-11-25 詹森药业有限公司 鲁贝洛唑n－氧化物
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
JP3404749B2 (ja) * 1996-06-27 2003-05-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｎ―［４―（ヘテロアリールメチル）フェニル］―ヘテロアリールアミン
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
NZ503491A (en) * 1997-11-10 2002-08-28 Bristol Myers Squibb Co 2-substituted amino-1,3-benzothiazole derivatives useful as protein tyrosine kinase inhibitors
GB9815785D0 (en) * 1998-07-20 1998-09-16 Cerebrus Ltd Chemical compounds
AU4537500A (en) 1999-05-12 2000-12-05 Neurosearch A/S Ion channel modulating agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963732A (en) * 1973-05-30 1976-06-15 Tiberio Bruzzese Process for preparing dihydroxydiphenylmethane derivatives
GB1458392A (en) * 1973-11-09 1976-12-15 Ici Ltd Optically-active 1-aryloxy-2,3-epoxypropane derivatives
US4310658A (en) * 1980-06-18 1982-01-12 Allied Corporation Production of polyester thermally stabilized with an oxirane
US4861785A (en) * 1984-12-03 1989-08-29 Janssen Pharmaceutica N.V. Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
US4689330A (en) * 1985-04-15 1987-08-25 Janssen Pharmaceutica N.V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
US4717760A (en) * 1986-07-10 1988-01-05 The Dow Chemical Company Fluorinated tris-epoxides based on triphenyl methane
JPH0643426B2 (ja) * 1986-07-25 1994-06-08 東京田辺製薬株式会社 イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Also Published As

Publication number Publication date
FI933719A7 (fi) 1993-08-24
NO933010D0 (no) 1993-08-24
IE920575A1 (en) 1992-08-26
FI933719L (fi) 1993-08-24
JP2825652B2 (ja) 1998-11-18
GR3018692T3 (en) 1996-04-30
DE69206787T2 (de) 1996-06-05
NO300591B1 (no) 1997-06-23
NZ241592A (en) 1994-07-26
ZA921341B (en) 1993-08-24
IL100952A0 (en) 1992-11-15
ES2083737T3 (es) 1996-04-16
RU2094434C1 (ru) 1997-10-27
DE69206787D1 (de) 1996-01-25
HUT67695A (en) 1995-04-28
LV11689B (en) 1997-08-20
CN1117048A (zh) 1996-02-21
CN1043609C (zh) 1999-06-16
SK278705B6 (sk) 1998-01-14
CN1064865A (zh) 1992-09-30
IL113837A0 (en) 1995-08-31
AU649788B2 (en) 1994-06-02
FI933719A0 (fi) 1993-08-24
NO933010L (no) 1993-08-24
RU2106348C1 (ru) 1998-03-10
DZ1560A1 (fr) 2002-02-17
US5675027A (en) 1997-10-07
EE02983B1 (et) 1997-04-15
IE69567B1 (en) 1996-10-02
RU95112519A (ru) 1997-04-20
CN1113437A (zh) 1995-12-20
CS51292A3 (en) 1992-09-16
ATE131478T1 (de) 1995-12-15
MA22447A1 (fr) 1992-10-01
US5434168A (en) 1995-07-18
DK0573473T3 (da) 1996-01-29
CZ284705B6 (cs) 1999-02-17
CN1033454C (zh) 1996-12-04
TNSN92017A1 (fr) 1993-06-08
EP0501552A1 (en) 1992-09-02
EP0573473B1 (en) 1995-12-13
IL100952A (en) 1995-12-31
BG98068A (bg) 1994-06-30
EP0573473A1 (en) 1993-12-15
PL168791B1 (pl) 1996-04-30
JPH06505012A (ja) 1994-06-09
RO112959B1 (ro) 1998-02-27
HU9302395D0 (en) 1993-11-29
MX9200777A (es) 1992-08-01
BG62332B1 (bg) 1999-08-31
CY1924A (en) 1997-03-07
CA2104000A1 (en) 1992-08-26
HU211560A9 (en) 1995-12-28
LV11689A (lv) 1997-02-20
WO1992014731A1 (en) 1992-09-03
TW218016B (enExample) 1993-12-21
IL113837A (en) 1996-05-14
KR0165901B1 (en) 1999-01-15
HK172296A (en) 1996-09-20
NZ248437A (en) 1994-07-26
AU1208592A (en) 1992-09-15

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