AU4005993A - New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them - Google Patents

New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them

Info

Publication number
AU4005993A
AU4005993A AU40059/93A AU4005993A AU4005993A AU 4005993 A AU4005993 A AU 4005993A AU 40059/93 A AU40059/93 A AU 40059/93A AU 4005993 A AU4005993 A AU 4005993A AU 4005993 A AU4005993 A AU 4005993A
Authority
AU
Australia
Prior art keywords
compounds
pyrrolothienopyrazine
processes
preparation
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU40059/93A
Other versions
AU659738B2 (en
Inventor
Gerhard Adam
Beatrice Guardiola-Lemaitre
Jean-Charles Lancelot
Sylvain Rault
Pierre Renard
Max Robba
Juan-Carlos Pilo Vicente
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of AU4005993A publication Critical patent/AU4005993A/en
Application granted granted Critical
Publication of AU659738B2 publication Critical patent/AU659738B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention relates to the compounds of general formula (I): <IMAGE> in which R1, R2, R3 and A are as defined in the description, to their optical isomers and to their addition salts with a pharmaceutically acceptable acid or base. Medicaments.
AU40059/93A 1992-06-05 1993-06-04 New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them Ceased AU659738B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9206800 1992-06-05
FR9206800A FR2691967B1 (en) 1992-06-05 1992-06-05 NOVEL PYRROLOTHIENOPYRAZINIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
AU4005993A true AU4005993A (en) 1993-12-09
AU659738B2 AU659738B2 (en) 1995-05-25

Family

ID=9430449

Family Applications (1)

Application Number Title Priority Date Filing Date
AU40059/93A Ceased AU659738B2 (en) 1992-06-05 1993-06-04 New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them

Country Status (11)

Country Link
EP (1) EP0573360B1 (en)
JP (1) JPH0794460B2 (en)
AT (1) ATE170187T1 (en)
AU (1) AU659738B2 (en)
CA (1) CA2097779A1 (en)
DE (1) DE69320542T2 (en)
DK (1) DK0573360T3 (en)
ES (1) ES2123038T3 (en)
FR (1) FR2691967B1 (en)
NZ (1) NZ247791A (en)
ZA (1) ZA933942B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3268003B1 (en) 2015-03-12 2020-07-29 Merck Sharp & Dohme Corp. Thienopyrazine inhibitors of irak4 activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997433A (en) * 1990-01-16 1991-03-05 Marlowe Goble E Endosteal fixation stud and system
FR2659332B1 (en) * 1990-03-08 1994-04-29 Adit Et Cie NOVEL PYRROLO [1,2-A] THIENO [3,2-F] DIAZEPINES [1,4], THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2660310B1 (en) * 1990-03-27 1992-06-05 Adir NOVEL 4H-PYRROLO [1,2A] THIENO [2,3-F] DIAZEPINE [1,4] DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
ZA933942B (en) 1993-12-30
AU659738B2 (en) 1995-05-25
FR2691967A1 (en) 1993-12-10
ES2123038T3 (en) 1999-01-01
DE69320542D1 (en) 1998-10-01
DE69320542T2 (en) 1999-04-29
JPH06172363A (en) 1994-06-21
EP0573360A1 (en) 1993-12-08
FR2691967B1 (en) 1995-06-09
DK0573360T3 (en) 1999-05-25
JPH0794460B2 (en) 1995-10-11
EP0573360B1 (en) 1998-08-26
ATE170187T1 (en) 1998-09-15
NZ247791A (en) 1994-12-22
CA2097779A1 (en) 1993-12-06

Similar Documents

Publication Publication Date Title
GR3018212T3 (en) Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them.
AU663200B2 (en) New 3-(hydroxybenzylidenyl)-indolin-2-ones, processes for their preparation and pharmaceutical compositions containing them
AU4616893A (en) New benzopyran compounds, process for their preparation and the pharmaceutical compositions which contain them
AU673893B2 (en) New pyridothiadiazones, processes for their preparation and the pharmaceutical compositions which contain them
AU6602394A (en) New alpha-amino acid compounds, a process for the preparation thereof and pharmaceutical compositions containing them
AU656674B2 (en) New thiochroman compounds, processes for the preparation thereof, and pharmaceutical compositions containing them
AU3559793A (en) New 3-aminochroman spiro compounds, processes for their preparation and pharmaceutical compositions containing them
AU668398B2 (en) New aminoalkylchromones, processes for the preparation thereof, and pharmaceutical compositions containing them
AU6187394A (en) New pyrrolopyrazine compounds, processes for their preparation and the pharmaceutical compositions which contain them
AU659738B2 (en) New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them
AU5511394A (en) New (cyclohexyl)alkene compounds, processes for preparing them and pharmaceutical compositions containing them
AU7753994A (en) New cyclised analogues of fatty acid metabolites a process for their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired