ZM987A1 - New dihydrobenzofuran and chroman-carboxamide derivatives,processes for the preparation thereof and use thereof as neuroleptics - Google Patents

New dihydrobenzofuran and chroman-carboxamide derivatives,processes for the preparation thereof and use thereof as neuroleptics

Info

Publication number
ZM987A1
ZM987A1 ZM9/87A ZM987A ZM987A1 ZM 987 A1 ZM987 A1 ZM 987A1 ZM 9/87 A ZM9/87 A ZM 9/87A ZM 987 A ZM987 A ZM 987A ZM 987 A1 ZM987 A1 ZM 987A1
Authority
ZM
Zambia
Prior art keywords
neuroleptics
dihydrobenzofuran
chroman
processes
preparation
Prior art date
Application number
ZM9/87A
Other languages
English (en)
Original Assignee
Delagrange Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delagrange Lab filed Critical Delagrange Lab
Publication of ZM987A1 publication Critical patent/ZM987A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyamides (AREA)
ZM9/87A 1986-01-30 1987-01-29 New dihydrobenzofuran and chroman-carboxamide derivatives,processes for the preparation thereof and use thereof as neuroleptics ZM987A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8601279A FR2593504B1 (fr) 1986-01-30 1986-01-30 Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques

Publications (1)

Publication Number Publication Date
ZM987A1 true ZM987A1 (en) 1987-09-30

Family

ID=9331629

Family Applications (1)

Application Number Title Priority Date Filing Date
ZM9/87A ZM987A1 (en) 1986-01-30 1987-01-29 New dihydrobenzofuran and chroman-carboxamide derivatives,processes for the preparation thereof and use thereof as neuroleptics

Country Status (40)

Country Link
US (1) US5006570A (es)
EP (1) EP0231139B1 (es)
JP (1) JPS62277376A (es)
KR (1) KR870007160A (es)
CN (2) CN1016420B (es)
AT (1) ATE70063T1 (es)
AU (1) AU593605B2 (es)
BE (1) BE1000164A5 (es)
BG (1) BG46600A3 (es)
CA (1) CA1300161C (es)
CH (1) CH670827A5 (es)
CS (2) CS264288B2 (es)
DD (1) DD260065A5 (es)
DE (2) DE3702005A1 (es)
DK (1) DK46987A (es)
ES (2) ES2003671A6 (es)
FI (1) FI870347A (es)
FR (1) FR2593504B1 (es)
GB (1) GB2187188B (es)
GR (2) GR870134B (es)
HU (1) HU206107B (es)
IE (1) IE870128L (es)
IL (1) IL81299A (es)
IN (2) IN164389B (es)
IS (1) IS1446B6 (es)
IT (1) IT1205729B (es)
LU (1) LU86747A1 (es)
MA (1) MA20861A1 (es)
NO (1) NO168582C (es)
NZ (1) NZ219068A (es)
OA (1) OA08472A (es)
PH (1) PH23392A (es)
PL (2) PL152404B1 (es)
PT (1) PT84224B (es)
SU (2) SU1609451A3 (es)
TN (1) TNSN87012A1 (es)
YU (1) YU46185B (es)
ZA (1) ZA87552B (es)
ZM (1) ZM987A1 (es)
ZW (1) ZW1387A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611713B1 (fr) * 1987-02-27 1990-11-30 Adir Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2611715B1 (fr) * 1987-02-27 1989-05-12 Adir Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
JP2726306B2 (ja) * 1989-04-14 1998-03-11 本田技研工業株式会社 車両の前後輪操舵装置
US5122361A (en) * 1989-04-17 1992-06-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and imaging agents
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
GB9005014D0 (en) 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
WO1991017144A1 (en) * 1990-05-02 1991-11-14 Yoshitomi Pharmaceutical Industries, Ltd. Amide compound, pharmaceutical use thereof and novel 1-substituted pyrrolidinemethyl-amines
US5114947A (en) * 1990-12-27 1992-05-19 Erbamont Inc. Method for alleviating anxiety using benzobicyclic carboxamides
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
JPH07503480A (ja) * 1992-02-06 1995-04-13 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 5−ht4拮抗薬としてのベンゾピラン,ベンゾチオピランおよびベンゾフラン誘導体
US5708174A (en) * 1992-03-12 1998-01-13 Smithkline Beecham P.L.C. Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists
US6127379A (en) * 1993-02-01 2000-10-03 Smithkline Beecham P.L.C. Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
JP2999669B2 (ja) * 1993-08-24 2000-01-17 株式会社三和化学研究所 ベンゾ[b]フランカルボキサミド誘導体、その製法及び用途
JPH0820586A (ja) 1994-07-05 1996-01-23 Sanwa Kagaku Kenkyusho Co Ltd 1−アザビシクロ[3.3.0]オクタン誘導体、その塩及び製法並びに用途
JPH0873463A (ja) * 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
JPS63139180A (ja) * 1986-12-02 1988-06-10 Tanabe Seiyaku Co Ltd カルボン酸誘導体

Also Published As

Publication number Publication date
FR2593504B1 (fr) 1988-12-09
IE870128L (en) 1987-07-30
DE3774888D1 (de) 1992-01-16
US5006570A (en) 1991-04-09
AU593605B2 (en) 1990-02-15
EP0231139A3 (en) 1988-04-27
OA08472A (fr) 1988-07-29
IT1205729B (it) 1989-03-31
YU46185B (sh) 1993-05-28
FR2593504A1 (fr) 1987-07-31
GR870134B (en) 1987-05-28
ZA87552B (en) 1987-10-28
IS3189A7 (is) 1987-07-31
IT8747583A0 (it) 1987-01-29
NO168582C (no) 1992-03-11
IN164389B (es) 1989-03-04
FI870347A0 (fi) 1987-01-27
HUT47093A (en) 1989-01-30
PT84224B (pt) 1989-03-30
CS36288A2 (en) 1988-09-16
BE1000164A5 (fr) 1988-07-05
IL81299A0 (en) 1987-08-31
ES2038679T3 (es) 1993-08-01
PH23392A (en) 1989-07-26
GR3003653T3 (es) 1993-03-16
ATE70063T1 (de) 1991-12-15
PL272298A1 (en) 1989-02-20
PL152491B1 (en) 1990-12-31
FI870347A (fi) 1987-07-31
MA20861A1 (fr) 1987-10-01
CN1062144A (zh) 1992-06-24
JPS62277376A (ja) 1987-12-02
NO870199L (no) 1987-07-31
EP0231139A2 (fr) 1987-08-05
BG46600A3 (en) 1990-01-15
DK46987A (da) 1987-07-31
NO168582B (no) 1991-12-02
PL263885A1 (en) 1988-09-15
DD260065A5 (de) 1988-09-14
CA1300161C (fr) 1992-05-05
PL152404B1 (en) 1990-12-31
DE3702005A1 (de) 1987-08-06
IS1446B6 (is) 1990-12-14
SU1609451A3 (ru) 1990-11-23
CS264300B2 (cs) 1989-06-13
PT84224A (fr) 1987-02-01
ES2003671A6 (es) 1988-11-01
GB8701870D0 (en) 1987-03-04
GB2187188A (en) 1987-09-03
HU206107B (en) 1992-08-28
TNSN87012A1 (fr) 1990-01-01
CS57887A2 (en) 1988-09-16
ZW1387A1 (en) 1987-10-28
NZ219068A (en) 1990-12-21
KR870007160A (ko) 1987-08-17
LU86747A1 (fr) 1987-06-02
YU11387A (en) 1988-06-30
SU1607688A3 (ru) 1990-11-15
CS264288B2 (en) 1989-06-13
GB2187188B (en) 1989-11-08
EP0231139B1 (fr) 1991-12-04
NO870199D0 (no) 1987-01-16
DK46987D0 (da) 1987-01-29
IN167060B (es) 1990-08-25
AU6785587A (en) 1987-08-06
CN87100978A (zh) 1987-09-16
CH670827A5 (es) 1989-07-14
CN1016420B (zh) 1992-04-29
IL81299A (en) 1991-09-16

Similar Documents

Publication Publication Date Title
ZM987A1 (en) New dihydrobenzofuran and chroman-carboxamide derivatives,processes for the preparation thereof and use thereof as neuroleptics
ATE62908T1 (de) Neue derivate von 4,5-dihydro-oxazolen, verfahren zu ihrer herstellung und ihre verwendung.
NO871575D0 (no) Fremgangsmaate for fremstilling av 1,5-benztiazepinderivater.
ZA925093B (en) 6-oxo-azepinoindol compounds as well as a process and intermediate products for the production thereof,and drugs that contain these compounds
ATE37368T1 (de) Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
AU658175B2 (en) Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
ATE170187T1 (de) Pyrrolothienopyrazin-verbindungen als 5ht3- rezeptoren-antagonisten