ZA989338B - Process for the synthesis of chloropurine intermediates. - Google Patents

Process for the synthesis of chloropurine intermediates.

Info

Publication number
ZA989338B
ZA989338B ZA9809338A ZA989338A ZA989338B ZA 989338 B ZA989338 B ZA 989338B ZA 9809338 A ZA9809338 A ZA 9809338A ZA 989338 A ZA989338 A ZA 989338A ZA 989338 B ZA989338 B ZA 989338B
Authority
ZA
South Africa
Prior art keywords
synthesis
chloropurine
intermediates
chloropurine intermediates
Prior art date
Application number
ZA9809338A
Other languages
English (en)
Inventor
Martin Francis Jones
Christopher John Wallis
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA989338B publication Critical patent/ZA989338B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA9809338A 1997-10-14 1998-10-13 Process for the synthesis of chloropurine intermediates. ZA989338B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9721780.6A GB9721780D0 (en) 1997-10-14 1997-10-14 Process for the synthesis of chloropurine intermediates

Publications (1)

Publication Number Publication Date
ZA989338B true ZA989338B (en) 2000-04-13

Family

ID=10820547

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9809338A ZA989338B (en) 1997-10-14 1998-10-13 Process for the synthesis of chloropurine intermediates.

Country Status (44)

Country Link
US (1) US6646125B1 (sk)
EP (1) EP1023292B1 (sk)
JP (1) JP4531250B2 (sk)
KR (1) KR100543845B1 (sk)
CN (1) CN1160354C (sk)
AP (1) AP1182A (sk)
AR (1) AR014921A1 (sk)
AT (1) ATE249461T1 (sk)
AU (1) AU738462B2 (sk)
BG (1) BG64597B1 (sk)
BR (1) BR9813048B1 (sk)
CA (1) CA2306958C (sk)
CO (1) CO4980899A1 (sk)
CZ (1) CZ294482B6 (sk)
DE (1) DE69818084T2 (sk)
DK (1) DK1023292T3 (sk)
EA (1) EA003183B1 (sk)
EE (1) EE04059B1 (sk)
EG (1) EG21730A (sk)
ES (1) ES2205553T3 (sk)
GB (1) GB9721780D0 (sk)
GE (1) GEP20022679B (sk)
HK (1) HK1027807A1 (sk)
HR (1) HRP20000216B1 (sk)
HU (1) HUP0003984A3 (sk)
ID (1) ID24927A (sk)
IL (1) IL135323A (sk)
IN (1) IN184590B (sk)
IS (1) IS2195B (sk)
MA (1) MA24676A1 (sk)
MY (1) MY127470A (sk)
NO (1) NO325030B1 (sk)
NZ (1) NZ503679A (sk)
OA (1) OA11370A (sk)
PE (1) PE121899A1 (sk)
PL (1) PL188477B1 (sk)
PT (1) PT1023292E (sk)
RS (1) RS49710B (sk)
SK (1) SK285331B6 (sk)
TR (1) TR200000976T2 (sk)
TW (1) TW436488B (sk)
UA (1) UA54550C2 (sk)
WO (1) WO1999019327A1 (sk)
ZA (1) ZA989338B (sk)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ298144B6 (cs) 1997-11-27 2007-07-04 Lonza Ag Zpusob výroby (1S,4R)- nebo (1R,4S)-4-(2-amino-6-chlor-9-H-purin-9-yl)-2-cyklopenten-1-methanolu
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
GB0320738D0 (en) 2003-09-04 2003-10-08 Glaxo Group Ltd Novel process
CN100465174C (zh) * 2006-06-13 2009-03-04 中国科学院上海有机化学研究所 制备光学纯阿巴卡韦的方法
KR101109476B1 (ko) * 2009-06-26 2012-01-31 현대제철 주식회사 실린더 교체용 지그장치
KR20170078868A (ko) 2010-01-27 2017-07-07 비이브 헬쓰케어 컴퍼니 항바이러스 치료
CN104672239A (zh) * 2013-11-26 2015-06-03 上海迪赛诺化学制药有限公司 一种采用一锅法制备阿巴卡韦式v中间体的工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS6175A (ja) * 1984-03-06 1986-01-06 ブリストル−マイア−ズ　コムパニ− 神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
IT1229531B (it) * 1988-01-20 1991-09-04 Univ Minnesota Composti nucleosidi dideossidideidrocarbociclici e formulazione farmaceutica che li contiene
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5329008A (en) * 1993-04-07 1994-07-12 Glaxo Inc. Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
SK284810B6 (sk) * 1997-05-13 2005-12-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu

Also Published As

Publication number Publication date
BG64597B1 (bg) 2005-08-31
AR014921A1 (es) 2001-04-11
MY127470A (en) 2006-12-29
CA2306958C (en) 2007-09-04
JP2001519432A (ja) 2001-10-23
EE04059B1 (et) 2003-06-16
TR200000976T2 (tr) 2000-11-21
AU9547698A (en) 1999-05-03
HUP0003984A2 (hu) 2001-04-28
KR20010015744A (ko) 2001-02-26
NO325030B1 (no) 2008-01-21
HRP20000216B1 (en) 2002-08-31
NZ503679A (en) 2002-09-27
PL188477B1 (pl) 2005-02-28
UA54550C2 (uk) 2003-03-17
NO20001896L (no) 2000-06-13
EA200000318A1 (ru) 2000-12-25
RS49710B (sr) 2007-12-31
DK1023292T3 (da) 2003-11-10
MA24676A1 (fr) 1999-07-01
EP1023292B1 (en) 2003-09-10
CZ20001367A3 (cs) 2000-10-11
DE69818084D1 (de) 2003-10-16
IL135323A0 (en) 2001-05-20
SK5362000A3 (en) 2001-03-12
EA003183B1 (ru) 2003-02-27
CA2306958A1 (en) 1999-04-22
IN184590B (sk) 2000-09-09
WO1999019327A1 (en) 1999-04-22
DE69818084T2 (de) 2004-07-15
CZ294482B6 (cs) 2005-01-12
IS5423A (is) 2000-03-28
KR100543845B1 (ko) 2006-01-23
YU20200A (sh) 2003-02-28
BG104352A (en) 2001-02-28
PE121899A1 (es) 1999-12-20
HUP0003984A3 (en) 2002-12-28
AP2000001790A0 (en) 2000-06-30
JP4531250B2 (ja) 2010-08-25
US6646125B1 (en) 2003-11-11
ID24927A (id) 2000-08-31
OA11370A (en) 2004-01-27
HRP20000216A2 (en) 2000-08-31
EG21730A (en) 2002-02-27
IS2195B (is) 2007-01-15
SK285331B6 (sk) 2006-11-03
CO4980899A1 (es) 2000-11-27
CN1160354C (zh) 2004-08-04
BR9813048A (pt) 2000-08-15
EP1023292A1 (en) 2000-08-02
NO20001896D0 (no) 2000-04-12
CN1281457A (zh) 2001-01-24
HK1027807A1 (en) 2001-01-23
PT1023292E (pt) 2004-02-27
IL135323A (en) 2004-07-25
BR9813048B1 (pt) 2010-07-13
ES2205553T3 (es) 2004-05-01
TW436488B (en) 2001-05-28
GEP20022679B (en) 2002-04-25
ATE249461T1 (de) 2003-09-15
PL339904A1 (en) 2001-01-15
GB9721780D0 (en) 1997-12-10
EE200000162A (et) 2001-04-16
AU738462B2 (en) 2001-09-20
AP1182A (en) 2003-06-18

Similar Documents

Publication Publication Date Title
ZA9811586B (en) Process for the synthesis of 1,3-diols
AU7287598A (en) Process for the conversion of hydrocarbons
IL133363A (en) Process for the production of herapin
IL133140A0 (en) Novel process for the preparation of 4-aryl-piperidines
ZA989338B (en) Process for the synthesis of chloropurine intermediates.
IL129868A0 (en) Process for the synthesis of benzothiopenes
HUP0003452A3 (en) Process for the preparation of 1-aryl-3-cyclopropyl-1,3-propanediones
ZA982255B (en) Process for the preparation of arylmalonates.
ZA987741B (en) Process for the preparation of oxazaphosphorine-2-amines
EP1038579A4 (en) PROCESS FOR THE PREPARATION OF CATALYSTS
ZA989241B (en) Process for the preparation of azacycloalkylalkanoyl pseudotetrapeptides
SI1023292T1 (en) Process for the synthesis of chloropurine intermediates
ZA979066B (en) Process for the synthesis of β-ketonitriles.
MXPA01001471A (es) Nuevo proceso para la sintesis de exoquelinas.
GB9807032D0 (en) Process for the preparation of (S)-3-carbethoxy-3-benzylpiperidine
GC0000093A (en) Process for the synthesis of pharmaceutically acceptable chloropurine intermediates.
ZA9710340B (en) Method for the synthesis of deoxypyridinoline.
EP1023271A4 (en) PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS THUS PRODUCED
IL131765A0 (en) Process for the purification of substituted p-nitrodiphenylethers
IL113555A0 (en) Process for the synthesis of haloalkylferrocenes
ZA963753B (en) Synthesis of benzoquinolinones.
IL132237A (en) Process for the preparation of 3-isochromanone
IL136026A0 (en) Process for the production of formylimidazoles
HUP9601521A3 (en) Process for preparing substituted quinoline-intermediates and the intermediates arising from the process
ZA981924B (en) Process for the preparation of n-carboxylalkyl-3-fluoro-4- dialkylaminoanilines