ZA985317B - Omeprazole sodium salt - Google Patents

Omeprazole sodium salt

Info

Publication number
ZA985317B
ZA985317B ZA985317A ZA985317A ZA985317B ZA 985317 B ZA985317 B ZA 985317B ZA 985317 A ZA985317 A ZA 985317A ZA 985317 A ZA985317 A ZA 985317A ZA 985317 B ZA985317 B ZA 985317B
Authority
ZA
South Africa
Prior art keywords
sodium salt
omeprazole sodium
omeprazole
salt
sodium
Prior art date
Application number
ZA985317A
Other languages
English (en)
Inventor
Anders Gustavsson
Kristina Kjellbom
Ingvar Ymen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA985317B publication Critical patent/ZA985317B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA985317A 1997-06-27 1998-06-18 Omeprazole sodium salt ZA985317B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9702483A SE510643C2 (sv) 1997-06-27 1997-06-27 Termodynamiskt stabil omeprazol natrium form B

Publications (1)

Publication Number Publication Date
ZA985317B true ZA985317B (en) 1999-01-11

Family

ID=20407555

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985317A ZA985317B (en) 1997-06-27 1998-06-18 Omeprazole sodium salt

Country Status (35)

Country Link
US (1) US6207188B1 (de)
EP (2) EP0991641B1 (de)
JP (1) JP3377218B2 (de)
KR (1) KR100580987B1 (de)
CN (1) CN1134432C (de)
AR (1) AR013350A1 (de)
AT (1) ATE233756T1 (de)
AU (1) AU750239B2 (de)
BR (1) BR9810483A (de)
CA (1) CA2294614C (de)
CZ (1) CZ296723B6 (de)
DE (1) DE69811892T2 (de)
DK (1) DK0991641T3 (de)
EE (1) EE03613B1 (de)
EG (1) EG24224A (de)
ES (1) ES2191944T3 (de)
HK (1) HK1026699A1 (de)
HU (1) HU227976B1 (de)
ID (1) ID24829A (de)
IL (2) IL133559A0 (de)
IS (1) IS1946B (de)
MY (1) MY127871A (de)
NO (1) NO318245B1 (de)
NZ (1) NZ501929A (de)
PL (1) PL190869B1 (de)
PT (1) PT991641E (de)
RU (1) RU2186778C2 (de)
SA (1) SA98190410B1 (de)
SE (1) SE510643C2 (de)
SK (1) SK283958B6 (de)
TR (1) TR199903270T2 (de)
TW (1) TW483758B (de)
UA (1) UA58556C2 (de)
WO (1) WO1999000380A1 (de)
ZA (1) ZA985317B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
GB2324093A (en) 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
WO2000071122A1 (en) * 1999-05-20 2000-11-30 Par Pharmaceutical, Inc. Stabilized composition based on pyridinyl-sulfinyl-benzimidazoles and process
SE9903831D0 (sv) 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US20030212274A1 (en) * 2000-05-15 2003-11-13 Bakthavathsalan Vijayaraghavan Novel amorphous form of omeprazole salts
EP1306375B1 (de) 2000-08-04 2006-10-11 Takeda Pharmaceutical Company Limited Salze von benzimidazol-derivaten und deren verwendung
WO2002015908A1 (fr) * 2000-08-18 2002-02-28 Takeda Chemical Industries, Ltd. Injections
EP1411900B2 (de) 2001-06-01 2013-12-04 Pozen, Inc. Pharmazeutische zusammensetzungen für die koordinierte abgabe von nsaid
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
EP1556043A1 (de) * 2002-10-22 2005-07-27 Ranbaxy Laboratories, Ltd. Amorphe form von esomeprazol-magnesiumsalz
CN1842525A (zh) 2003-05-05 2006-10-04 兰贝克赛实验室有限公司 苯并咪唑衍生物的钡盐
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
NZ551970A (en) * 2004-06-24 2010-01-29 Astrazeneca Ab New process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
WO2006073779A1 (en) * 2004-12-30 2006-07-13 Transform Phamaceuticals, Inc. Novel omeprazole forms and related methods
EP1907375B1 (de) * 2005-06-08 2013-07-24 LEK Pharmaceuticals d.d. Kristallines solvat von omeprazol-natrium
EA201100313A1 (ru) 2008-09-09 2011-10-31 Астразенека Аб Способ доставки фармацевтической композиции пациенту, нуждающемуся в этом
CN101412710B (zh) * 2008-12-16 2010-04-21 海南百那医药发展有限公司 一种奥美拉唑钠化合物及其制法
EP2445499A4 (de) 2009-06-25 2013-02-27 Astrazeneca Ab Verfahren zur behandlung eines patienten mit risiko der entwicklung eines nsaid-assoziierten geschwürs
CA2766524A1 (en) * 2009-06-25 2010-12-29 Pozen Inc. Method for treating a patient in need of aspirin therapy
CN102351846B (zh) * 2011-09-07 2012-08-22 周晓东 一种新的奥美拉唑钠化合物及其药物组合物
CN102319223B (zh) * 2011-09-21 2013-06-19 石药集团欧意药业有限公司 一种埃索美拉唑冻干制剂及其制备方法
CN102512380B (zh) * 2011-12-20 2013-04-17 海南锦瑞制药股份有限公司 一种以奥美拉唑钠为活性成分的冻干粉针剂及其制备方法
WO2013101897A2 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
CN102827147B (zh) * 2012-09-13 2013-08-07 山东罗欣药业股份有限公司 一种奥美拉唑钠晶体化合物及含有该晶体化合物的药物组合物
CN102871973A (zh) * 2012-10-16 2013-01-16 浙江亚太药业股份有限公司 一种奥美拉唑钠冻干制剂及其制备方法
CN103012371B (zh) * 2013-01-05 2014-02-12 宁辉 奥美拉唑钠结晶化合物、其制备方法及其药物组合物
CN103570687B (zh) * 2013-11-15 2015-01-07 悦康药业集团有限公司 一种奥美拉唑钠晶体化合物
CN104788426B (zh) * 2015-04-02 2015-12-30 天津大学 一种奥美拉唑钠半水合物及其制备方法
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2719916A1 (de) * 1977-05-04 1978-11-09 Kali Chemie Pharma Gmbh Verfahren zur herstellung von 2,9-dioxatricyclo eckige klammer auf 4,3,1,0 hoch 3,7 eckige klammer zu decanen
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
ES2023778A6 (es) * 1990-12-12 1992-02-01 Genesis Para La Investigacion Procedimiento para preparar sales alcalinas del omeprazol
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
CA2170647C (en) 1994-07-08 2001-03-13 Pontus John Arvid Bergstrand Multiple unit tableted dosage form i
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
CN1042423C (zh) * 1995-05-25 1999-03-10 常州市第四制药厂 奥美拉唑盐水合物及其制备方法
WO1998040377A1 (en) * 1997-03-07 1998-09-17 A/S Gea Farmaceutisk Fabrik Process for the preparation of 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose
EP0968205A1 (de) * 1997-03-07 2000-01-05 A/S GEA Farmaceutisk Fabrik Verfahren zur herstellung von 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazolen und dabei verwendbare neue verbindungen
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B

Also Published As

Publication number Publication date
TR199903270T2 (xx) 2000-07-21
SE9702483D0 (sv) 1997-06-27
SE510643C2 (sv) 1999-06-14
EE9900593A (et) 2000-08-15
SA98190410B1 (ar) 2006-06-10
TW483758B (en) 2002-04-21
UA58556C2 (uk) 2003-08-15
SK172999A3 (en) 2000-07-11
EP0991641B1 (de) 2003-03-05
DE69811892T2 (de) 2004-03-04
NO996440D0 (no) 1999-12-23
PL190869B1 (pl) 2006-02-28
HU227976B1 (en) 2012-07-30
EP1186602A2 (de) 2002-03-13
HK1026699A1 (en) 2000-12-22
CN1134432C (zh) 2004-01-14
EP1186602A3 (de) 2002-03-27
IS1946B (is) 2004-10-13
IS5314A (is) 1999-12-21
JP2001508805A (ja) 2001-07-03
AU750239B2 (en) 2002-07-11
RU2186778C2 (ru) 2002-08-10
CA2294614C (en) 2002-01-08
NO996440L (no) 2000-02-08
SE9702483L (sv) 1998-12-28
NO318245B1 (no) 2005-02-21
SK283958B6 (sk) 2004-06-08
IL133559A (en) 2006-04-10
ATE233756T1 (de) 2003-03-15
US6207188B1 (en) 2001-03-27
BR9810483A (pt) 2000-09-12
ID24829A (id) 2000-08-24
DE69811892D1 (de) 2003-04-10
JP3377218B2 (ja) 2003-02-17
HUP0003017A2 (hu) 2001-06-28
CZ296723B6 (cs) 2006-05-17
ES2191944T3 (es) 2003-09-16
MY127871A (en) 2006-12-29
AR013350A1 (es) 2000-12-27
KR100580987B1 (ko) 2006-05-17
HUP0003017A3 (en) 2002-01-28
IL133559A0 (en) 2001-04-30
CZ469999A3 (cs) 2000-08-16
CN1261362A (zh) 2000-07-26
NZ501929A (en) 2001-06-29
KR20010014165A (ko) 2001-02-26
PL337735A1 (en) 2000-08-28
PT991641E (pt) 2003-06-30
AU8135398A (en) 1999-01-19
WO1999000380A1 (en) 1999-01-07
EG24224A (en) 2008-11-10
DK0991641T3 (da) 2003-05-19
EE03613B1 (et) 2002-02-15
CA2294614A1 (en) 1999-01-07
EP0991641A1 (de) 2000-04-12

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