ZA9810765B - Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole. - Google Patents

Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.

Info

Publication number
ZA9810765B
ZA9810765B ZA9810765A ZA9810765A ZA9810765B ZA 9810765 B ZA9810765 B ZA 9810765B ZA 9810765 A ZA9810765 A ZA 9810765A ZA 9810765 A ZA9810765 A ZA 9810765A ZA 9810765 B ZA9810765 B ZA 9810765B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical composition
substituted pyridyl
vinyl pyrrolidone
benzimidazole
polymer
Prior art date
Application number
ZA9810765A
Other languages
English (en)
Inventor
Dilipkumar Thacharodi
Ashok Rampal
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of ZA9810765B publication Critical patent/ZA9810765B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA9810765A 1998-05-28 1998-11-25 Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole. ZA9810765B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8622498A 1998-05-28 1998-05-28

Publications (1)

Publication Number Publication Date
ZA9810765B true ZA9810765B (en) 1999-08-06

Family

ID=22197118

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810765A ZA9810765B (en) 1998-05-28 1998-11-25 Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.

Country Status (11)

Country Link
US (1) US20020128293A1 (zh)
EP (1) EP0960620B1 (zh)
CN (1) CN1136850C (zh)
AT (1) ATE315396T1 (zh)
AU (1) AU1979699A (zh)
BR (1) BR9910723A (zh)
DE (1) DE69833157T2 (zh)
ES (1) ES2256910T3 (zh)
RU (1) RU2216321C2 (zh)
WO (1) WO1999061022A1 (zh)
ZA (1) ZA9810765B (zh)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2298823C (en) * 1998-04-20 2011-06-07 Eisai Co., Ltd. Stabilized composition comprising a benzimidazole type compound
IL130602A0 (en) * 1999-06-22 2000-06-01 Dexcel Ltd Stable benzimidazole formulation
ES2168043B1 (es) 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
WO2001024780A2 (en) * 1999-10-01 2001-04-12 Natco Pharma Limited Soft gel capsule resistant to gastric juices
CA2387746C (en) 1999-10-20 2010-06-29 Koji Ukai Methods for stabilizing benzimidazole-based compounds
SI20720A (sl) * 2000-11-20 2002-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Nov farmacevtski pripravek v obliki celuloznih kapsul uporaben za derivate benzimidazola
US20030050620A1 (en) * 2001-09-07 2003-03-13 Isa Odidi Combinatorial type controlled release drug delivery device
US6620900B2 (en) * 2002-02-07 2003-09-16 Isp Investments Inc. Proliferous copolymer of vinyl pyrrolidone and vinyl acetate
DE10247037A1 (de) * 2002-10-09 2004-04-22 Abbott Gmbh & Co. Kg Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
PE20050150A1 (es) * 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
CL2004000983A1 (es) * 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US20050042277A1 (en) * 2003-07-17 2005-02-24 Irukulla Srinivas Pharmaceutical compositions having a swellable coating
WO2005027880A1 (en) * 2003-09-25 2005-03-31 Natco Pharma Limited Enteric soft gelatin capsule containing esomeprazole and method of preparation
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
WO2005051362A2 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating
EP1768668A2 (en) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8658216B2 (en) 2004-12-23 2014-02-25 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
US20080279951A1 (en) * 2005-02-02 2008-11-13 Rajesh Gandhi Stable Oral Benzimidazole Compositions Prepared by Non-Aqueous Layering Process
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US20070154542A1 (en) * 2005-12-30 2007-07-05 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
CA2648280C (en) 2006-04-03 2014-03-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
AR061166A1 (es) * 2006-06-01 2008-08-06 Schering Corp Composiciones farmaceuticas para la liberacion sostenida de fenilferina
WO2007138606A2 (en) * 2006-06-01 2007-12-06 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
KR20170097787A (ko) 2007-10-12 2017-08-28 다케다 파마슈티칼스 유에스에이, 인코포레이티드 음식 섭취와 관계없이 위장 장애를 치료하는 방법
US8911787B2 (en) 2008-02-26 2014-12-16 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
EP2293782B1 (en) * 2008-05-06 2015-08-12 Dexcel Pharma Technologies Ltd. Stable benzimidazole formulation
WO2011086194A1 (en) 2010-01-18 2011-07-21 Cephalon France Improved oral lysophilisates containing pvp/va
CN102940611B (zh) * 2012-11-26 2017-02-22 康普药业股份有限公司 一种含有埃索美拉唑镁的肠溶片剂
US20160256399A1 (en) 2013-11-04 2016-09-08 Capsugel Belgium Nv Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole
EP3209282A4 (en) * 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3216579A (en) * 1961-05-25 1965-11-09 Ind Biology Lab Inc Water-insoluble polyvinylpyrrolidone composition
US4139688A (en) * 1977-06-24 1979-02-13 Gaf Corporation Preparation of insoluble polyvinylpyrrolidone
US4180633A (en) * 1977-06-24 1979-12-25 Gaf Corporation Preparation of insoluble polyvinylpyrrolidone
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
DE2942657A1 (de) * 1979-10-22 1981-04-30 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von polyvinylpyrrolidon, dessen waessrige loesung eine hohe viskositaet aufweist, durch waermebehandlung von waessrigen loesungen von ueblichem polyvinylpyrrolidon
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
US5073614A (en) * 1990-10-18 1991-12-17 Isp Investments Inc. Strongly swellable, moderately crosslinked polyvinylpyrrolidone
YU48263B (sh) * 1991-06-17 1997-09-30 Byk Gulden Lomberg Chemische Fabrik Gmbh. Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola
US5178867A (en) * 1991-08-19 1993-01-12 Alza Corporation Dosage form for delivering drug in short-time period
US5252611A (en) * 1992-07-20 1993-10-12 Isp Investments Inc. Controlled release tablets including strongly swellable, moderately crosslinked polyvinylpyrrolidone
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
MX9600857A (es) * 1994-07-08 1997-06-28 Astra Ab Forma de dosificacion i en tabletas, con unidades multiples.
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
NZ318501A (en) * 1995-09-21 1999-06-29 Pharma Pass Llc Novel composition containing an acid-labile omeprazole and process for its preparation
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
DK173431B1 (da) * 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
US6228400B1 (en) * 1999-09-28 2001-05-08 Carlsbad Technology, Inc. Orally administered pharmaceutical formulations of benzimidazole derivatives and the method of preparing the same

Also Published As

Publication number Publication date
EP0960620A1 (en) 1999-12-01
WO1999061022A1 (en) 1999-12-02
ATE315396T1 (de) 2006-02-15
DE69833157T2 (de) 2006-08-31
CN1136850C (zh) 2004-02-04
EP0960620B1 (en) 2006-01-11
AU1979699A (en) 1999-12-13
DE69833157D1 (de) 2006-04-06
RU2216321C2 (ru) 2003-11-20
ES2256910T3 (es) 2006-07-16
BR9910723A (pt) 2001-06-12
US20020128293A1 (en) 2002-09-12
CN1237415A (zh) 1999-12-08

Similar Documents

Publication Publication Date Title
ZA9810765B (en) Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
AU777322B2 (en) Solid oral pharmaceutical formulation of modified release that contains an acid labile benzimidazole compound
EP1020460A3 (en) The sodium salt of the (-)-enantiomer of omeprazole
EP0392959A3 (en) Use of sertindole for the treatment of schizophrenia
ES2375269T3 (es) Preparado farmacéutico en forma de una pasta que comprende un ingrediente activo l�?bil ante los �?cidos.
WO1998000114A3 (de) Stabile arzneiform mit benzimidazolderivaten als wirkstoff zur oralen verabreichung und verfahren zu ihrer herstellung
IE921733A1 (en) Oral presentation forms for acid-unstable active compounds
HK1039742A1 (en) New stable multi-unitary pharmaceutical preparations containing substituted benzimidazoles
RU98122664A (ru) Устойчивая фармацевтическая композиция для перорального введения, содержащая замещенный пиридилсульфинилбензимидазол
HUP0201489A2 (hu) Új adagolási forma
NZ514129A (en) Tolperison-containing, pharmaceutical preparation for oral administration
IE64850B1 (en) Therapeutically active substituted benzimidazole and process for its preparation
KR20030059318A (ko) 산 불안정성 활성 성분을 포함하는 현탁액 형태의 약학 제제
AU8144387A (en) Medicaments for the treatment of addiction
ZA978099B (en) Controlled release pharmaceutical compositions for the oral administration containing nifedipine as active substance.
CA2089748A1 (en) Pharmaceutical compositions containing 5-difluoromethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl]benzimidazole and an anti-helicobacter agent for the treatment of gastrointestinal disorders
IE913232A1 (en) New oral drug forms
DE69907479D1 (de) Piroxicam enthaltende gastrointestinale Zubereitung aus merheren Einheiten bestehend
KR100605235B1 (ko) 판토프라졸 함유 경질 캡슐 제제 및 그 제조방법
CA2478958A1 (en) Use of proton pump inhibitors for the treatment of airway disorders
WO2003077916A1 (en) Use of proton pump inhibitors for the treatment of noncardiac chest pain
JP2005075788A (ja) ベンズイミダゾール系医薬組成物
IL122719A0 (en) Controlled release pharmaceutical compositions for oral administration containing nifedipine as active substance