DE69833157D1 - Stabile orale pharmazeutische Zusammensetzung enthaltend ein Pyridylsulfinyl-substituiertes Benzimidazole - Google Patents
Stabile orale pharmazeutische Zusammensetzung enthaltend ein Pyridylsulfinyl-substituiertes BenzimidazoleInfo
- Publication number
- DE69833157D1 DE69833157D1 DE69833157T DE69833157T DE69833157D1 DE 69833157 D1 DE69833157 D1 DE 69833157D1 DE 69833157 T DE69833157 T DE 69833157T DE 69833157 T DE69833157 T DE 69833157T DE 69833157 D1 DE69833157 D1 DE 69833157D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical composition
- substituted pyridyl
- vinyl pyrrolidone
- polymer
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8622498A | 1998-05-28 | 1998-05-28 | |
US86224 | 1998-05-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69833157D1 true DE69833157D1 (de) | 2006-04-06 |
DE69833157T2 DE69833157T2 (de) | 2006-08-31 |
Family
ID=22197118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69833157T Expired - Fee Related DE69833157T2 (de) | 1998-05-28 | 1998-12-07 | Stabile orale pharmazeutische Zusammensetzung enthaltend ein substituiertes Pyridylsulfinylbenzimidazol |
Country Status (11)
Country | Link |
---|---|
US (1) | US20020128293A1 (de) |
EP (1) | EP0960620B1 (de) |
CN (1) | CN1136850C (de) |
AT (1) | ATE315396T1 (de) |
AU (1) | AU1979699A (de) |
BR (1) | BR9910723A (de) |
DE (1) | DE69833157T2 (de) |
ES (1) | ES2256910T3 (de) |
RU (1) | RU2216321C2 (de) |
WO (1) | WO1999061022A1 (de) |
ZA (1) | ZA9810765B (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1004305B1 (de) * | 1998-04-20 | 2011-09-28 | Eisai R&D Management Co., Ltd. | Stabilisierte zusammenstellungen die benzimidazole enthalten |
IL130602A0 (en) * | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
ES2168043B1 (es) | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
DE60016617T2 (de) * | 1999-10-01 | 2005-04-28 | Natco Pharma Ltd., Banjara Hills | Magensaftresistente gelartige weichkapsel |
CA2387746C (en) | 1999-10-20 | 2010-06-29 | Koji Ukai | Methods for stabilizing benzimidazole-based compounds |
SI20720A (sl) * | 2000-11-20 | 2002-06-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Nov farmacevtski pripravek v obliki celuloznih kapsul uporaben za derivate benzimidazola |
US20030050620A1 (en) * | 2001-09-07 | 2003-03-13 | Isa Odidi | Combinatorial type controlled release drug delivery device |
US6620900B2 (en) * | 2002-02-07 | 2003-09-16 | Isp Investments Inc. | Proliferous copolymer of vinyl pyrrolidone and vinyl acetate |
DE10247037A1 (de) | 2002-10-09 | 2004-04-22 | Abbott Gmbh & Co. Kg | Herstellung von festen Dosierungsformen unter Verwendung eines vernetzten nichtthermoplastischen Trägers |
MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
CL2004000983A1 (es) * | 2003-05-08 | 2005-03-04 | Altana Pharma Ag | Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y |
PE20050150A1 (es) * | 2003-05-08 | 2005-03-22 | Altana Pharma Ag | Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo |
US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
RU2375048C2 (ru) * | 2003-07-17 | 2009-12-10 | Д-Р Редди'С Лабораторис Инк. | Фармацевтическая композиция с набухающим покрытием |
AU2003272081A1 (en) * | 2003-09-25 | 2005-04-11 | Natco Pharma Limited | Enteric soft gelatin capsule containing esomeprazole and method of preparation |
TWI372066B (en) | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
CA2547398A1 (en) * | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating |
EP1768668A2 (de) | 2004-06-16 | 2007-04-04 | Tap Pharmaceutical Products, Inc. | Multi-ppi-dosierform |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
WO2006067599A2 (en) | 2004-12-23 | 2006-06-29 | Ranbaxy Laboratories Limited | Stable oral benzimidazole compositions and process of preparation thereof |
EP1845982A2 (de) * | 2005-02-02 | 2007-10-24 | Ranbaxy Laboratories Limited | Durch ein nichtwässriges schichtungsverfahren hergestellte stabile orale benzimidaziol-zusammensetzungen |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
EP1965774A2 (de) * | 2005-12-30 | 2008-09-10 | Cogentus Pharmaceuticals, Inc. | Orale pharmazeutische formulierungen mit nichtsteroidalen entzündungshemmern und säurehemmern |
US9561188B2 (en) | 2006-04-03 | 2017-02-07 | Intellipharmaceutics Corporation | Controlled release delivery device comprising an organosol coat |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
TWI405567B (zh) * | 2006-06-01 | 2013-08-21 | Merck Sharp & Dohme | 持續釋放脫羥腎上腺素之醫藥組合物 |
US20100297226A1 (en) * | 2006-06-01 | 2010-11-25 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
RU2013106514A (ru) | 2007-10-12 | 2015-03-10 | Такеда Фармасьютикалз Норт Америка, Инк. | Способы лечения нарушений желудочно-кишечного тракта независимо от потребления пищи |
US8911787B2 (en) | 2008-02-26 | 2014-12-16 | Ranbaxy Laboratories Limited | Stable oral benzimidazole compositions and process of preparation thereof |
EP2293782B1 (de) * | 2008-05-06 | 2015-08-12 | Dexcel Pharma Technologies Ltd. | Stabile benzimidazolformulierung |
WO2011086194A1 (en) | 2010-01-18 | 2011-07-21 | Cephalon France | Improved oral lysophilisates containing pvp/va |
CN102940611B (zh) * | 2012-11-26 | 2017-02-22 | 康普药业股份有限公司 | 一种含有埃索美拉唑镁的肠溶片剂 |
EP3065720A1 (de) * | 2013-11-04 | 2016-09-14 | Capsugel Belgium NV | Verfahren und systeme zur verbesserten bioverfügbarkeit von aktiven pharmazeutischen inhaltsstoffen mit esomeprazol |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3216579A (en) * | 1961-05-25 | 1965-11-09 | Ind Biology Lab Inc | Water-insoluble polyvinylpyrrolidone composition |
US4180633A (en) * | 1977-06-24 | 1979-12-25 | Gaf Corporation | Preparation of insoluble polyvinylpyrrolidone |
US4139688A (en) * | 1977-06-24 | 1979-02-13 | Gaf Corporation | Preparation of insoluble polyvinylpyrrolidone |
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
DE2942657A1 (de) * | 1979-10-22 | 1981-04-30 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von polyvinylpyrrolidon, dessen waessrige loesung eine hohe viskositaet aufweist, durch waermebehandlung von waessrigen loesungen von ueblichem polyvinylpyrrolidon |
IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
US5073614A (en) * | 1990-10-18 | 1991-12-17 | Isp Investments Inc. | Strongly swellable, moderately crosslinked polyvinylpyrrolidone |
YU48263B (sh) * | 1991-06-17 | 1997-09-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola |
US5178867A (en) * | 1991-08-19 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug in short-time period |
US5252611A (en) * | 1992-07-20 | 1993-10-12 | Isp Investments Inc. | Controlled release tablets including strongly swellable, moderately crosslinked polyvinylpyrrolidone |
FR2692146B1 (fr) * | 1992-06-16 | 1995-06-02 | Ethypharm Sa | Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention. |
EE03305B1 (et) * | 1994-07-08 | 2000-12-15 | Astra Aktiebolag | Paljuosaline tableteeritud annusvorm I |
ES2094694B1 (es) * | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion. |
DE69631834T2 (de) * | 1995-09-21 | 2005-02-10 | Pharma Pass Ii Llc, Irvine | Neues ein säureempfindliches benzimidazol enthaltendes mittel und verfahren zu dessen herstellung |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
SE9704869D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
DK173431B1 (da) * | 1998-03-20 | 2000-10-23 | Gea Farmaceutisk Fabrik As | Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs |
US6228400B1 (en) * | 1999-09-28 | 2001-05-08 | Carlsbad Technology, Inc. | Orally administered pharmaceutical formulations of benzimidazole derivatives and the method of preparing the same |
-
1998
- 1998-11-25 ZA ZA9810765A patent/ZA9810765B/xx unknown
- 1998-12-07 EP EP98123251A patent/EP0960620B1/de not_active Expired - Lifetime
- 1998-12-07 ES ES98123251T patent/ES2256910T3/es not_active Expired - Lifetime
- 1998-12-07 AT AT98123251T patent/ATE315396T1/de not_active IP Right Cessation
- 1998-12-07 DE DE69833157T patent/DE69833157T2/de not_active Expired - Fee Related
- 1998-12-09 RU RU98122664/14A patent/RU2216321C2/ru not_active IP Right Cessation
- 1998-12-18 CN CNB981255280A patent/CN1136850C/zh not_active Expired - Fee Related
-
1999
- 1999-01-26 AU AU19796/99A patent/AU1979699A/en not_active Abandoned
- 1999-01-26 BR BR9910723-6A patent/BR9910723A/pt not_active Application Discontinuation
- 1999-01-26 WO PCT/IB1999/000139 patent/WO1999061022A1/en active Application Filing
-
2001
- 2001-10-09 US US09/973,265 patent/US20020128293A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1237415A (zh) | 1999-12-08 |
CN1136850C (zh) | 2004-02-04 |
DE69833157T2 (de) | 2006-08-31 |
EP0960620B1 (de) | 2006-01-11 |
AU1979699A (en) | 1999-12-13 |
ATE315396T1 (de) | 2006-02-15 |
US20020128293A1 (en) | 2002-09-12 |
WO1999061022A1 (en) | 1999-12-02 |
RU2216321C2 (ru) | 2003-11-20 |
BR9910723A (pt) | 2001-06-12 |
ES2256910T3 (es) | 2006-07-16 |
ZA9810765B (en) | 1999-08-06 |
EP0960620A1 (de) | 1999-12-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69833157D1 (de) | Stabile orale pharmazeutische Zusammensetzung enthaltend ein Pyridylsulfinyl-substituiertes Benzimidazole | |
AU777322B2 (en) | Solid oral pharmaceutical formulation of modified release that contains an acid labile benzimidazole compound | |
ES2675581T3 (es) | Método para producir gránulos de un compuesto de bencimidazol recubiertos | |
EP1020460A3 (de) | Das Natrium Salz des (-)-Enantiomer von Omeprazole | |
EP0392959A3 (de) | Verwendung von Sertindol zur Behandlung von Schizophrenie | |
SE8804629A (de) | ||
NO20023313L (no) | Nye substituerte benzimidazol doseringsformer og fremgangsmåte for anvendelse av samme | |
HUP0201489A2 (hu) | Új adagolási forma | |
WO1998000114A3 (de) | Stabile arzneiform mit benzimidazolderivaten als wirkstoff zur oralen verabreichung und verfahren zu ihrer herstellung | |
NZ514129A (en) | Tolperison-containing, pharmaceutical preparation for oral administration | |
SE8804628A (de) | ||
WO2001013898A3 (en) | Pharmaceutical formulations with different release times | |
ZA978099B (en) | Controlled release pharmaceutical compositions for the oral administration containing nifedipine as active substance. | |
BG60101A3 (en) | Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le | |
WO2000048445A3 (de) | Pharmazeutische zusammensetzung enthaltend desoxypeganin zur behandlung der nikotinabhängigkeit | |
DE69907479D1 (de) | Piroxicam enthaltende gastrointestinale Zubereitung aus merheren Einheiten bestehend | |
DE68907091T2 (de) | Scleroglucan und Wirkstoff enthaltende pharmazeutische Tabletten und Kapselgranulate. | |
JO1653B1 (en) | The current benzimidazole is a therapeutically active method for preparing it | |
IL122719A0 (en) | Controlled release pharmaceutical compositions for oral administration containing nifedipine as active substance | |
JP2005075788A (ja) | ベンズイミダゾール系医薬組成物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |