ZA976479B - Alfa-amino acids amides, preparation thereof and the therapeutical use thereof. - Google Patents

Alfa-amino acids amides, preparation thereof and the therapeutical use thereof.

Info

Publication number
ZA976479B
ZA976479B ZA9706479A ZA976479A ZA976479B ZA 976479 B ZA976479 B ZA 976479B ZA 9706479 A ZA9706479 A ZA 9706479A ZA 976479 A ZA976479 A ZA 976479A ZA 976479 B ZA976479 B ZA 976479B
Authority
ZA
South Africa
Prior art keywords
alfa
preparation
amino acids
therapeutical use
acids amides
Prior art date
Application number
ZA9706479A
Other languages
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Maurizio Delcanale
Renato De Fanti
Elisabetta Armani
Gino Villetti
Claudio Pietra
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of ZA976479B publication Critical patent/ZA976479B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9706479A 1996-07-23 1997-07-22 Alfa-amino acids amides, preparation thereof and the therapeutical use thereof. ZA976479B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI001544A IT1283489B1 (it) 1996-07-23 1996-07-23 Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico

Publications (1)

Publication Number Publication Date
ZA976479B true ZA976479B (en) 1998-03-02

Family

ID=11374651

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9706479A ZA976479B (en) 1996-07-23 1997-07-22 Alfa-amino acids amides, preparation thereof and the therapeutical use thereof.

Country Status (26)

Country Link
US (1) US6114391A (cs)
EP (1) EP0951465B1 (cs)
JP (1) JP4542208B2 (cs)
CN (1) CN1211351C (cs)
AR (1) AR007963A1 (cs)
AT (1) ATE237584T1 (cs)
AU (1) AU729176B2 (cs)
CA (1) CA2261259C (cs)
CZ (1) CZ295824B6 (cs)
DE (1) DE69721052T2 (cs)
DK (1) DK0951465T3 (cs)
ES (1) ES2195158T3 (cs)
HU (1) HU225623B1 (cs)
ID (1) ID17999A (cs)
IL (1) IL128020A (cs)
IT (1) IT1283489B1 (cs)
MY (1) MY118244A (cs)
NO (1) NO326826B3 (cs)
NZ (1) NZ333869A (cs)
PT (1) PT951465E (cs)
RU (1) RU2174511C2 (cs)
SI (1) SI0951465T1 (cs)
TR (1) TR199900087T2 (cs)
TW (1) TW557291B (cs)
WO (1) WO1998003472A1 (cs)
ZA (1) ZA976479B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672746A (en) 1994-08-30 1997-09-30 American Biogenetic Sciences, Inc. Antiproliferative and neurotrophic molecules
BR9911421A (pt) 1998-06-22 2001-03-27 American Biogenetic Sciences Uso de análogo do ácido valpróico para o tratamento e prevenção da enxaqueca e doenças emocionais
US20030035784A1 (en) 2001-03-05 2003-02-20 Kao Corporation Hair cosmetic, aminocarboxylic acid amide and method for producing the same
DK1321139T3 (da) * 2001-12-21 2007-01-02 Chiesi Farma Spa 2-indanylaminoderivater til behandling af kronisk, akut eller inflammatorisk smerte
FR2843590B1 (fr) * 2002-08-14 2007-10-05 Prestwick Scient Capital Inc Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
US20040082543A1 (en) * 2002-10-29 2004-04-29 Pharmacia Corporation Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
PL1778623T3 (pl) * 2004-08-03 2008-12-31 Chiesi Farm Spa Pochodne kwasów 1-fenyloalkanokarboksylowych do leczenia chorób neurodegeneracyjnych
WO2014178083A1 (en) 2013-05-03 2014-11-06 Council Of Scientific & Industrial Research An improved synthesis of anti-parkinson agent
CN105646252A (zh) * 2016-02-25 2016-06-08 吉尔生化（上海）有限公司 一种丝氨酸酰胺盐酸盐的合成方法
KR102286897B1 (ko) 2019-06-25 2021-08-09 (주)앰틱스바이오 신규한 아미노알칸산에 바이페닐기를 도입한 유도체 화합물 및 이를 포함하는 항진균성 약학적 조성물
WO2022238507A1 (en) * 2021-05-11 2022-11-17 Awakn Ls Europe Holdings Limited Therapeutic aminoindane compounds and compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3050800C2 (cs) * 1979-03-22 1989-06-22 Continental Pharma Inc., Bruessel/Bruxelles, Be
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
NL8800260A (nl) * 1988-02-04 1989-09-01 Stamicarbon Alpha-n-hydroxyaminozuren, amiden en andere derivaten daarvan.
CN1022837C (zh) * 1988-03-16 1993-11-24 卫材株式会社 制备头孢烯衍生物的方法
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5198547A (en) * 1992-03-16 1993-03-30 South Alabama Medical Science Foundation, Usa Process for N5-formylating tetrahydropteridines
GB9306886D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
US5332840A (en) * 1993-05-27 1994-07-26 Bristol-Myers Squibb Company Method for preparing a benzaldehyde intermediate
HU223083B1 (hu) * 1994-06-28 2004-03-29 Bayer Ag. Fungicid hatású aminosavszármazékok, eljárás előállításukra és alkalmazásuk

Also Published As

Publication number Publication date
CA2261259A1 (en) 1998-01-29
CA2261259C (en) 2006-10-03
ITMI961544A1 (it) 1998-01-23
DK0951465T3 (da) 2003-08-11
NZ333869A (en) 2000-05-26
NO326826B1 (no) 2009-02-23
ATE237584T1 (de) 2003-05-15
CN1225625A (zh) 1999-08-11
IL128020A0 (en) 1999-11-30
JP2001506577A (ja) 2001-05-22
RU2174511C2 (ru) 2001-10-10
AU729176B2 (en) 2001-01-25
DE69721052T2 (de) 2004-02-05
IL128020A (en) 2002-04-21
PT951465E (pt) 2003-08-29
NO990300L (no) 1999-01-22
NO990300D0 (no) 1999-01-22
ES2195158T3 (es) 2003-12-01
EP0951465B1 (en) 2003-04-16
ITMI961544A0 (cs) 1996-07-23
MY118244A (en) 2004-09-30
CN1211351C (zh) 2005-07-20
HU225623B1 (en) 2007-05-02
US6114391A (en) 2000-09-05
CZ18299A3 (cs) 1999-06-16
CZ295824B6 (cs) 2005-11-16
AR007963A1 (es) 1999-11-24
JP4542208B2 (ja) 2010-09-08
TR199900087T2 (xx) 1999-03-22
AU3695297A (en) 1998-02-10
HUP9902992A3 (en) 2004-04-28
TW557291B (en) 2003-10-11
NO326826B3 (no) 2010-06-07
SI0951465T1 (en) 2003-08-31
WO1998003472A1 (en) 1998-01-29
DE69721052D1 (de) 2003-05-22
ID17999A (id) 1998-02-19
IT1283489B1 (it) 1998-04-21
EP0951465A1 (en) 1999-10-27

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