SI0951465T1 - Alpha-amino acid amides, preparation thereof and the therapeutical use thereof - Google Patents

Alpha-amino acid amides, preparation thereof and the therapeutical use thereof

Info

Publication number
SI0951465T1
SI0951465T1 SI9730515T SI9730515T SI0951465T1 SI 0951465 T1 SI0951465 T1 SI 0951465T1 SI 9730515 T SI9730515 T SI 9730515T SI 9730515 T SI9730515 T SI 9730515T SI 0951465 T1 SI0951465 T1 SI 0951465T1
Authority
SI
Slovenia
Prior art keywords
alpha
preparation
amino acid
acid amides
therapeutical use
Prior art date
Application number
SI9730515T
Other languages
English (en)
Slovenian (sl)
Inventor
Paolo Chiesi
Paolo Ventura
Maurizio Delcanale
Fanti Renato De
Elisabetta Armani
Gino Villetti
Claudio Pietra
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of SI0951465T1 publication Critical patent/SI0951465T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI9730515T 1996-07-23 1997-07-15 Alpha-amino acid amides, preparation thereof and the therapeutical use thereof SI0951465T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96MI001544A IT1283489B1 (it) 1996-07-23 1996-07-23 Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
PCT/EP1997/003773 WO1998003472A1 (en) 1996-07-23 1997-07-15 Alpha-amino acid amides, preparation thereof and the therapeutical use thereof
EP97933680A EP0951465B1 (en) 1996-07-23 1997-07-15 Alpha-amino acid amides, preparation thereof and the therapeutical use thereof

Publications (1)

Publication Number Publication Date
SI0951465T1 true SI0951465T1 (en) 2003-08-31

Family

ID=11374651

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730515T SI0951465T1 (en) 1996-07-23 1997-07-15 Alpha-amino acid amides, preparation thereof and the therapeutical use thereof

Country Status (26)

Country Link
US (1) US6114391A (cs)
EP (1) EP0951465B1 (cs)
JP (1) JP4542208B2 (cs)
CN (1) CN1211351C (cs)
AR (1) AR007963A1 (cs)
AT (1) ATE237584T1 (cs)
AU (1) AU729176B2 (cs)
CA (1) CA2261259C (cs)
CZ (1) CZ295824B6 (cs)
DE (1) DE69721052T2 (cs)
DK (1) DK0951465T3 (cs)
ES (1) ES2195158T3 (cs)
HU (1) HU225623B1 (cs)
ID (1) ID17999A (cs)
IL (1) IL128020A (cs)
IT (1) IT1283489B1 (cs)
MY (1) MY118244A (cs)
NO (1) NO326826B3 (cs)
NZ (1) NZ333869A (cs)
PT (1) PT951465E (cs)
RU (1) RU2174511C2 (cs)
SI (1) SI0951465T1 (cs)
TR (1) TR199900087T2 (cs)
TW (1) TW557291B (cs)
WO (1) WO1998003472A1 (cs)
ZA (1) ZA976479B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672746A (en) 1994-08-30 1997-09-30 American Biogenetic Sciences, Inc. Antiproliferative and neurotrophic molecules
US6268396B1 (en) 1998-06-22 2001-07-31 American Biogenetic Sciences, Inc. Use of valproic acid analog for the treatment and prevention of migraine and affective illness
US20030035784A1 (en) 2001-03-05 2003-02-20 Kao Corporation Hair cosmetic, aminocarboxylic acid amide and method for producing the same
ATE336990T1 (de) * 2001-12-21 2006-09-15 Chiesi Farma Spa 2-indanylaminoderivate zur therapie von chronischen, akuten oder entzündlichen schmerzen
FR2843590B1 (fr) * 2002-08-14 2007-10-05 Prestwick Scient Capital Inc Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
US20040082543A1 (en) * 2002-10-29 2004-04-29 Pharmacia Corporation Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
EP1778623B1 (en) * 2004-08-03 2008-07-02 CHIESI FARMACEUTICI S.p.A. Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases
WO2014178083A1 (en) 2013-05-03 2014-11-06 Council Of Scientific & Industrial Research An improved synthesis of anti-parkinson agent
CN105646252A (zh) * 2016-02-25 2016-06-08 吉尔生化（上海）有限公司 一种丝氨酸酰胺盐酸盐的合成方法
BR112021026076A2 (pt) 2019-06-25 2022-03-29 Amtixbio Co Ltd Composto derivado introduzindo o grupo bifenila no novo ácido aminoalcanoico e composição farmacêutica antifúngica compreendendo o mesmo
CA3218884A1 (en) * 2021-05-11 2022-11-17 David Nutt Therapeutic aminoindane compounds and compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3010599A1 (de) * 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
NL8800260A (nl) * 1988-02-04 1989-09-01 Stamicarbon Alpha-n-hydroxyaminozuren, amiden en andere derivaten daarvan.
CA1339738C (en) * 1988-03-16 1998-03-17 Takashi Kamiya Process for the preparation of cephem derivatives and entermediates therefor
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5198547A (en) * 1992-03-16 1993-03-30 South Alabama Medical Science Foundation, Usa Process for N5-formylating tetrahydropteridines
GB9306886D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
US5332840A (en) * 1993-05-27 1994-07-26 Bristol-Myers Squibb Company Method for preparing a benzaldehyde intermediate
JP3959108B2 (ja) * 1994-06-28 2007-08-15 バイエル・アクチエンゲゼルシヤフト アミノ酸誘導体及びその有害生物防除剤としての使用

Also Published As

Publication number Publication date
ES2195158T3 (es) 2003-12-01
CA2261259C (en) 2006-10-03
DE69721052D1 (de) 2003-05-22
WO1998003472A1 (en) 1998-01-29
TR199900087T2 (xx) 1999-03-22
HUP9902992A3 (en) 2004-04-28
NZ333869A (en) 2000-05-26
IL128020A0 (en) 1999-11-30
AU3695297A (en) 1998-02-10
HU225623B1 (en) 2007-05-02
IT1283489B1 (it) 1998-04-21
ZA976479B (en) 1998-03-02
CZ295824B6 (cs) 2005-11-16
NO326826B3 (no) 2010-06-07
ID17999A (id) 1998-02-19
JP4542208B2 (ja) 2010-09-08
CN1225625A (zh) 1999-08-11
CZ18299A3 (cs) 1999-06-16
DK0951465T3 (da) 2003-08-11
CA2261259A1 (en) 1998-01-29
ITMI961544A1 (it) 1998-01-23
IL128020A (en) 2002-04-21
CN1211351C (zh) 2005-07-20
DE69721052T2 (de) 2004-02-05
NO990300L (no) 1999-01-22
MY118244A (en) 2004-09-30
NO326826B1 (no) 2009-02-23
AR007963A1 (es) 1999-11-24
PT951465E (pt) 2003-08-29
JP2001506577A (ja) 2001-05-22
NO990300D0 (no) 1999-01-22
EP0951465A1 (en) 1999-10-27
TW557291B (en) 2003-10-11
AU729176B2 (en) 2001-01-25
US6114391A (en) 2000-09-05
ITMI961544A0 (cs) 1996-07-23
RU2174511C2 (ru) 2001-10-10
EP0951465B1 (en) 2003-04-16
ATE237584T1 (de) 2003-05-15

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