FR2843590B1 - Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique - Google Patents

Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique

Info

Publication number
FR2843590B1
FR2843590B1 FR0210306A FR0210306A FR2843590B1 FR 2843590 B1 FR2843590 B1 FR 2843590B1 FR 0210306 A FR0210306 A FR 0210306A FR 0210306 A FR0210306 A FR 0210306A FR 2843590 B1 FR2843590 B1 FR 2843590B1
Authority
FR
France
Prior art keywords
derivatives
amino
hydroxypropanoic acid
glycinergic
action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0210306A
Other languages
English (en)
Other versions
FR2843590A1 (fr
Inventor
Smith Kathleen Clarence
Jean Marie Georges Contreras
Laurence Nathalie Deyon
Camille Georges Wermuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PRESTWICK SCIENT CAPITAL Inc
Original Assignee
PRESTWICK SCIENT CAPITAL Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PRESTWICK SCIENT CAPITAL Inc filed Critical PRESTWICK SCIENT CAPITAL Inc
Priority to FR0210306A priority Critical patent/FR2843590B1/fr
Priority to UAA200501927A priority patent/UA80559C2/uk
Priority to JP2004528582A priority patent/JP2005535715A/ja
Priority to AU2003274213A priority patent/AU2003274213B2/en
Priority to MXPA05001761A priority patent/MXPA05001761A/es
Priority to EP03758195A priority patent/EP1529030A2/fr
Priority to KR1020077013426A priority patent/KR100890674B1/ko
Priority to PL03375413A priority patent/PL375413A1/xx
Priority to NZ538633A priority patent/NZ538633A/en
Priority to KR1020057002073A priority patent/KR100756138B1/ko
Priority to CA002497347A priority patent/CA2497347A1/fr
Priority to EA200500333A priority patent/EA010417B1/ru
Priority to US10/524,869 priority patent/US7488755B2/en
Priority to BR0313740-6A priority patent/BR0313740A/pt
Priority to GEAP8683A priority patent/GEP20074194B/en
Priority to CNA038188481A priority patent/CN1675169A/zh
Priority to PCT/FR2003/002447 priority patent/WO2004016580A2/fr
Publication of FR2843590A1 publication Critical patent/FR2843590A1/fr
Priority to IL16677805A priority patent/IL166778A0/xx
Priority to NO20050961A priority patent/NO20050961L/no
Priority to CR7736A priority patent/CR7736A/es
Application granted granted Critical
Publication of FR2843590B1 publication Critical patent/FR2843590B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0210306A 2002-08-14 2002-08-14 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique Expired - Fee Related FR2843590B1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR0210306A FR2843590B1 (fr) 2002-08-14 2002-08-14 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
UAA200501927A UA80559C2 (en) 2002-08-14 2003-01-08 The derivatives of r(+)-2-amino-3-hydroxypropanoic acid having the glycinergic action
BR0313740-6A BR0313740A (pt) 2002-08-14 2003-08-01 Derivados do ácido r(+)-2-amino-3-hidróxi-propanóico com ação glicinérgica
MXPA05001761A MXPA05001761A (es) 2002-08-14 2003-08-01 Derivado de acido r(+)-2-amino-3-hidroxipropanoico con accion glicinergica.
EP03758195A EP1529030A2 (fr) 2002-08-14 2003-08-01 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
KR1020077013426A KR100890674B1 (ko) 2002-08-14 2003-08-01 글리신성 ｒ(+)-2-아미노-3-히드록시프로판산 유도체
PL03375413A PL375413A1 (en) 2002-08-14 2003-08-01 Derivatives of glycinergic r(+)-2-amino-3-hydroxypropanoic acid
NZ538633A NZ538633A (en) 2002-08-14 2003-08-01 R(+)-2-amino-3-hydroxypropanoic acid derivatives with glycinergic action
KR1020057002073A KR100756138B1 (ko) 2002-08-14 2003-08-01 글리신성 ｒ(+)-2-아미노-3-히드록시프로판산 유도체
CA002497347A CA2497347A1 (fr) 2002-08-14 2003-08-01 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
JP2004528582A JP2005535715A (ja) 2002-08-14 2003-08-01 グリシン作動性を有するｒ（＋）−２−アミノ−３−ヒドロキシプロピオン酸誘導体
US10/524,869 US7488755B2 (en) 2002-08-14 2003-08-01 Derivatives of glycinergic R(+)-2-amino-3-hydroxypropanoic acid
AU2003274213A AU2003274213B2 (en) 2002-08-14 2003-08-01 Derivatives of glycinergic R(+)-2-amino-3-hydroxypropanoic acid
GEAP8683A GEP20074194B (en) 2002-08-14 2003-08-01 Derivatives of glycinergic r(+)-2-amino-3-hydroxypropanoic acid
CNA038188481A CN1675169A (zh) 2002-08-14 2003-08-01 具有甘氨酸能作用的r(+)－2－氨基－3－羟基丙酸衍生物
PCT/FR2003/002447 WO2004016580A2 (fr) 2002-08-14 2003-08-01 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
EA200500333A EA010417B1 (ru) 2002-08-14 2003-08-01 Производные r(+)-2-амино-3-гидроксипропионовой кислоты с глицинэргическим действием
IL16677805A IL166778A0 (en) 2002-08-14 2005-02-09 Derivatives of gl ycinergic r(+)-2-amino-3-hydroxypropanoic acid
NO20050961A NO20050961L (no) 2002-08-14 2005-02-23 R(+)-2-Amino-3-Hydroksypropansyrederivater med glysinergisk virkning
CR7736A CR7736A (es) 2002-08-14 2005-03-11 Derivado de acido r(+)-2 amino -3-hidroxipropanoico con accion glicinergica

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0210306A FR2843590B1 (fr) 2002-08-14 2002-08-14 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique

Publications (2)

Publication Number Publication Date
FR2843590A1 FR2843590A1 (fr) 2004-02-20
FR2843590B1 true FR2843590B1 (fr) 2007-10-05

Family

ID=30775996

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0210306A Expired - Fee Related FR2843590B1 (fr) 2002-08-14 2002-08-14 Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique

Country Status (19)

Country Link
US (1) US7488755B2 (fr)
EP (1) EP1529030A2 (fr)
JP (1) JP2005535715A (fr)
KR (2) KR100890674B1 (fr)
CN (1) CN1675169A (fr)
AU (1) AU2003274213B2 (fr)
BR (1) BR0313740A (fr)
CA (1) CA2497347A1 (fr)
CR (1) CR7736A (fr)
EA (1) EA010417B1 (fr)
FR (1) FR2843590B1 (fr)
GE (1) GEP20074194B (fr)
IL (1) IL166778A0 (fr)
MX (1) MXPA05001761A (fr)
NO (1) NO20050961L (fr)
NZ (1) NZ538633A (fr)
PL (1) PL375413A1 (fr)
UA (1) UA80559C2 (fr)
WO (1) WO2004016580A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9199916B2 (en) * 2011-11-10 2015-12-01 Ramamohan Rao Davuluri Process for the preparation of (R)-N-benzyl-2-acetamido-3-methoxypropionamide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03236315A (ja) * 1989-12-05 1991-10-22 Nippon Oil & Fats Co Ltd 抗精神病薬
US5332758A (en) * 1990-07-13 1994-07-26 Kanebo, Ltd. Collagen metabolism ameliorant and its use
ES2036926B1 (es) * 1991-08-08 1994-01-16 Uriach & Cia Sa J "procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
GB9425730D0 (en) 1994-12-20 1995-02-22 Nycomed Pharma As Compounds
PT871440E (pt) * 1995-12-07 2006-07-31 Daniel C Javitt Tratamento de sintomas negativos e cognitivos de esquizofrenia com antagonistas da captacao de glicina
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
IL139008A0 (en) * 1998-04-14 2001-11-25 Gen Hospital Corp Methods for treating neuropsychiatric disorders
GB2410947B (en) 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
AU2003274213A1 (en) 2004-03-03
CR7736A (es) 2008-10-10
GEP20074194B (en) 2007-09-10
EA010417B1 (ru) 2008-08-29
EA200500333A1 (ru) 2005-08-25
KR20050055697A (ko) 2005-06-13
KR100756138B1 (ko) 2007-09-05
CA2497347A1 (fr) 2004-02-26
US7488755B2 (en) 2009-02-10
AU2003274213B2 (en) 2008-03-13
BR0313740A (pt) 2005-07-19
UA80559C2 (en) 2007-10-10
IL166778A0 (en) 2006-01-15
EP1529030A2 (fr) 2005-05-11
WO2004016580A3 (fr) 2004-04-08
US20050261372A1 (en) 2005-11-24
FR2843590A1 (fr) 2004-02-20
JP2005535715A (ja) 2005-11-24
PL375413A1 (en) 2005-11-28
MXPA05001761A (es) 2005-04-25
WO2004016580A2 (fr) 2004-02-26
NZ538633A (en) 2007-10-26
KR20070067250A (ko) 2007-06-27
NO20050961L (no) 2005-04-28
KR100890674B1 (ko) 2009-03-26
CN1675169A (zh) 2005-09-28

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Legal Events

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ST Notification of lapse

Effective date: 20130430