ZA966313B - Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents, and medicaments comprising them. - Google Patents
Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents, and medicaments comprising them.Info
- Publication number
- ZA966313B ZA966313B ZA9606313A ZA966313A ZA966313B ZA 966313 B ZA966313 B ZA 966313B ZA 9606313 A ZA9606313 A ZA 9606313A ZA 966313 A ZA966313 A ZA 966313A ZA 966313 B ZA966313 B ZA 966313B
- Authority
- ZA
- South Africa
- Prior art keywords
- medicaments
- preparation
- cinnamic acid
- diagnostic agents
- substituted cinnamic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19527305A DE19527305A1 (de) | 1995-07-26 | 1995-07-26 | Substituierte Zimtsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA966313B true ZA966313B (en) | 1997-02-11 |
Family
ID=7767840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9606313A ZA966313B (en) | 1995-07-26 | 1996-07-25 | Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents, and medicaments comprising them. |
Country Status (29)
Country | Link |
---|---|
US (1) | US5883133A (xx) |
EP (1) | EP0755919B1 (xx) |
JP (1) | JP4177466B2 (xx) |
KR (1) | KR970006281A (xx) |
CN (1) | CN1062554C (xx) |
AR (1) | AR003467A1 (xx) |
AT (1) | ATE186720T1 (xx) |
AU (1) | AU704461B2 (xx) |
BR (1) | BR9603179A (xx) |
CA (1) | CA2182062C (xx) |
CZ (1) | CZ289327B6 (xx) |
DE (2) | DE19527305A1 (xx) |
DK (1) | DK0755919T3 (xx) |
ES (1) | ES2140765T3 (xx) |
GR (1) | GR3032363T3 (xx) |
HR (1) | HRP960356B1 (xx) |
HU (1) | HUP9602072A3 (xx) |
IL (1) | IL118925A (xx) |
MX (1) | MX9603004A (xx) |
MY (1) | MY115466A (xx) |
NO (1) | NO306060B1 (xx) |
NZ (1) | NZ299052A (xx) |
PL (1) | PL183439B1 (xx) |
RU (1) | RU2190601C2 (xx) |
SI (1) | SI0755919T1 (xx) |
SK (1) | SK282018B6 (xx) |
TR (1) | TR199600612A2 (xx) |
TW (1) | TW536531B (xx) |
ZA (1) | ZA966313B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19527305A1 (de) * | 1995-07-26 | 1997-01-30 | Hoechst Ag | Substituierte Zimtsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
US6878700B1 (en) | 1998-12-29 | 2005-04-12 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
US6867203B2 (en) | 1998-12-29 | 2005-03-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
US6110922A (en) | 1998-12-29 | 2000-08-29 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
DE10024319A1 (de) * | 2000-05-17 | 2001-11-22 | Merck Patent Gmbh | Bisacylguanidine |
GB0015205D0 (en) * | 2000-06-21 | 2000-08-09 | Karobio Ab | Bioisosteric thyroid receptor ligands and method |
US6521619B2 (en) | 2000-06-29 | 2003-02-18 | Icos Corporation | Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents |
JP2004502681A (ja) * | 2000-06-29 | 2004-01-29 | アボット・ラボラトリーズ | アリールフェニル複素環スルフィド誘導体および細胞接着を阻止する抗炎症性および免疫抑制性物質としてのその使用 |
DE10046993A1 (de) * | 2000-09-22 | 2002-04-11 | Aventis Pharma Gmbh | Substituierte Zimtsäureguanidide, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltendes Medikament |
AU2002357032B2 (en) * | 2001-11-29 | 2009-01-08 | Theracos, Inc | Compounds for treatment of inflammation, diabetes and related disorders |
DE10258168B4 (de) * | 2002-12-12 | 2005-07-07 | Infineon Technologies Ag | Integrierter DRAM-Halbleiterspeicher und Verfahren zum Betrieb desselben |
NZ544671A (en) | 2003-06-26 | 2009-02-28 | Biotron Ltd | Antiviral compounds and methods |
PL2826770T3 (pl) | 2005-06-24 | 2019-02-28 | Biotron Limited | Przeciwwirusowe związki acyloguanidynowe |
US20120088737A2 (en) * | 2009-10-02 | 2012-04-12 | Ajinomoto Co., Inc | Novel acyl guanidine derivatives |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2734904A (en) * | 1956-02-14 | Xcxnhxc-nh | ||
US4544670A (en) | 1982-08-24 | 1985-10-01 | William H. Rorer, Inc. | Method of treating coccidiosis with acyl guanidines |
CZ284456B6 (cs) * | 1992-02-15 | 1998-12-16 | Hoechst Aktiengesellschaft | Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje |
CN1036267C (zh) * | 1992-02-15 | 1997-10-29 | 赫彻斯特股份公司 | 氨基取代的苯甲酰胍的制备方法 |
DE4325822A1 (de) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19527305A1 (de) * | 1995-07-26 | 1997-01-30 | Hoechst Ag | Substituierte Zimtsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1995
- 1995-07-26 DE DE19527305A patent/DE19527305A1/de not_active Withdrawn
-
1996
- 1996-05-16 PL PL96314279A patent/PL183439B1/pl unknown
- 1996-07-19 EP EP96111665A patent/EP0755919B1/de not_active Expired - Lifetime
- 1996-07-19 AT AT96111665T patent/ATE186720T1/de not_active IP Right Cessation
- 1996-07-19 DK DK96111665T patent/DK0755919T3/da active
- 1996-07-19 ES ES96111665T patent/ES2140765T3/es not_active Expired - Lifetime
- 1996-07-19 DE DE59603659T patent/DE59603659D1/de not_active Expired - Lifetime
- 1996-07-19 SI SI9630144T patent/SI0755919T1/xx unknown
- 1996-07-23 CN CN96110200A patent/CN1062554C/zh not_active Expired - Fee Related
- 1996-07-24 US US08/686,999 patent/US5883133A/en not_active Expired - Lifetime
- 1996-07-24 AR ARP960103724A patent/AR003467A1/es unknown
- 1996-07-24 MY MYPI96003033A patent/MY115466A/en unknown
- 1996-07-24 CZ CZ19962184A patent/CZ289327B6/cs not_active IP Right Cessation
- 1996-07-24 IL IL11892596A patent/IL118925A/en not_active IP Right Cessation
- 1996-07-24 AU AU60668/96A patent/AU704461B2/en not_active Ceased
- 1996-07-24 SK SK965-96A patent/SK282018B6/sk unknown
- 1996-07-24 TR TR96/00612A patent/TR199600612A2/xx unknown
- 1996-07-24 NZ NZ299052A patent/NZ299052A/en unknown
- 1996-07-25 MX MX9603004A patent/MX9603004A/es not_active IP Right Cessation
- 1996-07-25 ZA ZA9606313A patent/ZA966313B/xx unknown
- 1996-07-25 RU RU96115333/04A patent/RU2190601C2/ru not_active IP Right Cessation
- 1996-07-25 BR BR9603179-4A patent/BR9603179A/pt unknown
- 1996-07-25 NO NO963108A patent/NO306060B1/no unknown
- 1996-07-25 HR HR19527305.2 patent/HRP960356B1/xx not_active IP Right Cessation
- 1996-07-25 JP JP19628396A patent/JP4177466B2/ja not_active Expired - Fee Related
- 1996-07-25 CA CA002182062A patent/CA2182062C/en not_active Expired - Fee Related
- 1996-07-26 HU HU9602072A patent/HUP9602072A3/hu unknown
- 1996-07-26 KR KR1019960031743A patent/KR970006281A/ko not_active Application Discontinuation
- 1996-08-23 TW TW085110279A patent/TW536531B/zh active
-
2000
- 2000-01-14 GR GR20000400061T patent/GR3032363T3/el not_active IP Right Cessation
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