ZA962657B - Pharmaceutical composition containing proton pump inhibitors - Google Patents

Pharmaceutical composition containing proton pump inhibitors

Info

Publication number
ZA962657B
ZA962657B ZA962657A ZA962657A ZA962657B ZA 962657 B ZA962657 B ZA 962657B ZA 962657 A ZA962657 A ZA 962657A ZA 962657 A ZA962657 A ZA 962657A ZA 962657 B ZA962657 B ZA 962657B
Authority
ZA
South Africa
Prior art keywords
proton pump
pharmaceutical composition
composition containing
pump inhibitors
containing proton
Prior art date
Application number
ZA962657A
Other languages
English (en)
Inventor
Kaushik K Dave
James B Williams
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA962657B publication Critical patent/ZA962657B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA962657A 1995-04-04 1996-04-03 Pharmaceutical composition containing proton pump inhibitors ZA962657B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/416,275 US5708017A (en) 1995-04-04 1995-04-04 Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors

Publications (1)

Publication Number Publication Date
ZA962657B true ZA962657B (en) 1996-10-09

Family

ID=23649308

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA962657A ZA962657B (en) 1995-04-04 1996-04-03 Pharmaceutical composition containing proton pump inhibitors

Country Status (30)

Country Link
US (1) US5708017A (fr)
EP (1) EP0819004B1 (fr)
JP (1) JP4603631B2 (fr)
KR (1) KR100419105B1 (fr)
CN (1) CN1080119C (fr)
AT (1) ATE438380T1 (fr)
AU (1) AU703755B2 (fr)
BR (1) BR9604803A (fr)
CA (1) CA2217515C (fr)
CY (1) CY2613B2 (fr)
CZ (1) CZ287297B6 (fr)
DE (1) DE69637985D1 (fr)
DK (1) DK0819004T3 (fr)
EA (1) EA000087B1 (fr)
EE (1) EE03473B1 (fr)
ES (1) ES2329098T3 (fr)
HK (1) HK1004658A1 (fr)
HU (1) HU227864B1 (fr)
IS (1) IS2706B (fr)
MX (1) MX9707694A (fr)
NO (1) NO312994B1 (fr)
NZ (1) NZ305708A (fr)
PL (1) PL183144B1 (fr)
PT (1) PT819004E (fr)
SI (1) SI0819004T1 (fr)
SK (1) SK282872B6 (fr)
TR (1) TR199701117T1 (fr)
UA (1) UA42061C2 (fr)
WO (1) WO1996031213A1 (fr)
ZA (1) ZA962657B (fr)

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CA2298823C (fr) * 1998-04-20 2011-06-07 Eisai Co., Ltd. Composition stabilisee comprenant un compose de type benzimidazole
HUP0103464A3 (en) * 1998-08-10 2002-11-28 U S Government Represented By Prodrugs of proton pump inhibitors and pharmaceutical compositions containing them
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
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EA004683B1 (ru) 1999-02-23 2004-06-24 Мерк Энд Ко., Инк. Фармацевтическая композиция, содержащая омепразол
FR2793688B1 (fr) 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
CA2387746C (fr) 1999-10-20 2010-06-29 Koji Ukai Procede de stabilisation de composes a base de benzimidazoles
GB2358136A (en) * 2000-01-15 2001-07-18 Univ Montfort A medicament for the treatment of equine oral stereotypies using a pH regulator
US6787342B2 (en) * 2000-02-16 2004-09-07 Merial Limited Paste formulations
DE60142515D1 (de) 2000-05-30 2010-08-19 Merial Ltd Zusammensetzungen zur vorbeugung von geschwüren in pferden
US6544556B1 (en) * 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
AU2001296908A1 (en) * 2000-09-29 2002-04-08 Geneva Pharmaceuticals, Inc. Proton pump inhibitor formulation
WO2002032427A1 (fr) * 2000-10-20 2002-04-25 Galephar M/F Formulation stable administrable par voie orale contenant un derive de benzimidazole
EP1331927B1 (fr) * 2000-10-27 2007-12-12 Leo Pharma A/S Composition topique contenant au moins une vitamine d ou un analogue de vitamine d et au moins un corticosteroide
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BR0312802A (pt) * 2002-07-19 2005-04-19 Michael E Garst Pró-drogas de inibidores de bombas de próton
GB2394895A (en) * 2002-11-06 2004-05-12 Cipla Ltd Proton pump inhibitor composition in paste form
EP1596821A2 (fr) * 2003-01-24 2005-11-23 The State Of Israel-Ministry Of Agriculture Compositions synergiques et procedes pour potentialiser une activite antioxydante
EP2112920B1 (fr) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Capsules contenant un inhibiteur de la pompe a protons comprenant des unites secondaires differemment structurees permettant une liberation retardee de l'ingredient actif
WO2005000269A1 (fr) * 2003-06-26 2005-01-06 Cipla Limited Preparations pharmaceutiques contenant un inhibiteur de la pompe a protons
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
WO2005039640A1 (fr) * 2003-10-03 2005-05-06 Allergan Inc. Compositions contenant des peptides en trefle et/ou des mucoadhesifs et des promedicaments d'un inhibiteur de pompe a proton
AU2005216863A1 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Methods and compositions for the intravenous administration of compounds related to proton pump inhibitors
JP2007523163A (ja) * 2004-02-18 2007-08-16 アラーガン、インコーポレイテッド プロトンポンプインヒビターのプロドラッグの投与のための方法および組成物
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US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
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Also Published As

Publication number Publication date
HK1004658A1 (en) 1998-12-04
CN1185107A (zh) 1998-06-17
WO1996031213A1 (fr) 1996-10-10
BR9604803A (pt) 1998-06-09
IS2706B (is) 2011-01-15
PL322619A1 (en) 1998-02-02
AU5379796A (en) 1996-10-23
CA2217515C (fr) 2005-03-15
EE9700244A (et) 1998-04-15
DK0819004T3 (da) 2009-11-30
ATE438380T1 (de) 2009-08-15
EP0819004A4 (fr) 2006-01-18
ES2329098T3 (es) 2009-11-20
CN1080119C (zh) 2002-03-06
PT819004E (pt) 2009-10-12
KR100419105B1 (ko) 2004-05-31
SI0819004T1 (sl) 2009-12-31
SK135097A3 (en) 1998-06-03
US5708017A (en) 1998-01-13
KR19980703576A (ko) 1998-11-05
EA199700294A1 (ru) 1998-02-26
AU703755B2 (en) 1999-04-01
NO974589D0 (no) 1997-10-03
CY2613B2 (en) 2011-04-06
UA42061C2 (uk) 2001-10-15
NZ305708A (en) 1999-11-29
HUP9801626A3 (en) 2000-06-28
SK282872B6 (sk) 2003-01-09
HUP9801626A2 (hu) 1999-02-01
MX9707694A (es) 1997-12-31
JPH11503160A (ja) 1999-03-23
PL183144B1 (pl) 2002-05-31
CZ287297B6 (en) 2000-10-11
CA2217515A1 (fr) 1996-10-10
TR199701117T1 (xx) 1998-02-21
EE03473B1 (et) 2001-08-15
EP0819004A1 (fr) 1998-01-21
IS4576A (is) 1997-10-02
EA000087B1 (ru) 1998-06-25
DE69637985D1 (de) 2009-09-17
EP0819004B1 (fr) 2009-08-05
CZ313597A3 (cs) 1998-04-15
JP4603631B2 (ja) 2010-12-22
NO312994B1 (no) 2002-07-29
HU227864B1 (en) 2012-05-29
NO974589L (no) 1997-12-03

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