ZA962502B - Monomeric insulin analog formulations. - Google Patents

Monomeric insulin analog formulations.

Info

Publication number
ZA962502B
ZA962502B ZA9602502A ZA962502A ZA962502B ZA 962502 B ZA962502 B ZA 962502B ZA 9602502 A ZA9602502 A ZA 9602502A ZA 962502 A ZA962502 A ZA 962502A ZA 962502 B ZA962502 B ZA 962502B
Authority
ZA
South Africa
Prior art keywords
insulin analog
monomeric insulin
analog formulations
formulations
monomeric
Prior art date
Application number
ZA9602502A
Other languages
English (en)
Inventor
Michael Rosario De Felippis
Bruce Hill Frank
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA962502B publication Critical patent/ZA962502B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
ZA9602502A 1995-03-31 1996-03-28 Monomeric insulin analog formulations. ZA962502B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41488095A 1995-03-31 1995-03-31

Publications (1)

Publication Number Publication Date
ZA962502B true ZA962502B (en) 1997-09-29

Family

ID=23643384

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9602502A ZA962502B (en) 1995-03-31 1996-03-28 Monomeric insulin analog formulations.

Country Status (23)

Country Link
US (1) US5952297A (ru)
EP (1) EP0735048A1 (ru)
JP (1) JPH11502856A (ru)
KR (1) KR19980703425A (ru)
CN (1) CN1185114A (ru)
AR (1) AR002976A1 (ru)
AU (1) AU720300B2 (ru)
BR (1) BR9607935A (ru)
CA (1) CA2216516A1 (ru)
CO (1) CO4700482A1 (ru)
CZ (1) CZ305297A3 (ru)
EA (1) EA000970B1 (ru)
HU (1) HUP9801700A3 (ru)
IL (1) IL117696A (ru)
MX (1) MX9707428A (ru)
NO (1) NO974498L (ru)
NZ (1) NZ305719A (ru)
PE (1) PE38797A1 (ru)
PL (1) PL322626A1 (ru)
TR (1) TR199701078T1 (ru)
WO (1) WO1996030040A1 (ru)
YU (1) YU18596A (ru)
ZA (1) ZA962502B (ru)

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CN1125081C (zh) 1999-09-08 2003-10-22 中国科学院上海生物化学研究所 重组天然和新型人胰岛素及其制备方法
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US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
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US7312192B2 (en) * 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
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US7683029B2 (en) * 2003-05-07 2010-03-23 Philip Morris Usa Inc. Liquid aerosol formulations containing insulin and aerosol generating devices and methods for generating aerosolized insulin
CA2580313C (en) 2004-07-19 2016-03-15 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
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EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
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US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
US9408893B2 (en) 2011-08-29 2016-08-09 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
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WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
WO2014088836A1 (en) 2012-12-03 2014-06-12 Merck Sharp & Dohme Corp. O-glycosylated carboxy terminal portion (ctp) peptide-based insulin and insulin analogues
US9670162B2 (en) 2013-03-14 2017-06-06 The Board Of Trustees Of The Leland Stanford Junio Mitochondrial aldehyde dehyrogenase-2 modulators and methods of use thereof
CA2907848A1 (en) 2013-04-03 2014-10-09 Sanofi Treatment of diabetes mellitus by long-acting formulations of insulins
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
EP3077414B1 (en) 2013-12-04 2020-06-17 Merck Sharp & Dohme Corp. Method for preparing crystalline insulin
RS64124B1 (sr) 2014-05-07 2023-05-31 Boehringer Ingelheim Int Inhalator i kontejner
DK3139984T3 (da) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Forstøver
ES2954961T3 (es) 2014-05-07 2023-11-27 Boehringer Ingelheim Int Unidad, nebulizador y método
WO2016007682A1 (en) * 2014-07-08 2016-01-14 Amphastar Pharmaceuticals Inc. Micronized insulin, micronized insulin analogues, and methods of manufacturing the same
US10124040B2 (en) 2014-08-26 2018-11-13 Merck Sharp & Dohme Corp. Method for preparing crystalline insulin or insulin analog compositions
LT3229828T (lt) 2014-12-12 2023-06-12 Sanofi-Aventis Deutschland Gmbh Insulino glargino/liksisenatido fiksuoto santykio kompozicija
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Also Published As

Publication number Publication date
BR9607935A (pt) 1998-06-02
CO4700482A1 (es) 1998-12-29
WO1996030040A1 (en) 1996-10-03
CZ305297A3 (cs) 1998-02-18
NO974498D0 (no) 1997-09-29
EA199700285A1 (ru) 1998-02-26
IL117696A (en) 2000-01-31
CA2216516A1 (en) 1996-10-03
AU720300B2 (en) 2000-05-25
US5952297A (en) 1999-09-14
NZ305719A (en) 1998-09-24
IL117696A0 (en) 1996-07-23
EA000970B1 (ru) 2000-08-28
NO974498L (no) 1997-10-08
AR002976A1 (es) 1998-05-27
PE38797A1 (es) 1997-10-04
YU18596A (sh) 1998-07-10
KR19980703425A (ko) 1998-11-05
EP0735048A1 (en) 1996-10-02
AU5381296A (en) 1996-10-16
HUP9801700A2 (hu) 1998-11-30
TR199701078T1 (xx) 1998-01-21
MX9707428A (es) 1997-12-31
CN1185114A (zh) 1998-06-17
JPH11502856A (ja) 1999-03-09
PL322626A1 (en) 1998-02-02
HUP9801700A3 (en) 1998-12-28

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