ZA961231B - Substituted benzenesulfonyllureas and -thioureas process for their preparation their use as a medicament or diagnostic and medicament containing them - Google Patents

Substituted benzenesulfonyllureas and -thioureas process for their preparation their use as a medicament or diagnostic and medicament containing them

Info

Publication number
ZA961231B
ZA961231B ZA961231A ZA961231A ZA961231B ZA 961231 B ZA961231 B ZA 961231B ZA 961231 A ZA961231 A ZA 961231A ZA 961231 A ZA961231 A ZA 961231A ZA 961231 B ZA961231 B ZA 961231B
Authority
ZA
South Africa
Prior art keywords
medicament
benzenesulfonyllureas
thioureas
diagnostic
substituted
Prior art date
Application number
ZA961231A
Other languages
English (en)
Inventor
Heinrich Englert
Uwe Gerlach
Dieter Mania
Heinz Goegelein
Joachim Kaiser
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA961231B publication Critical patent/ZA961231B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42—Sulfonylthioureas; Sulfonylisothioureas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA961231A 1995-02-17 1996-02-16 Substituted benzenesulfonyllureas and -thioureas process for their preparation their use as a medicament or diagnostic and medicament containing them ZA961231B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19505397A DE19505397A1 (de) 1995-02-17 1995-02-17 Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
ZA961231B true ZA961231B (en) 1996-08-27

Family

ID=7754249

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA961231A ZA961231B (en) 1995-02-17 1996-02-16 Substituted benzenesulfonyllureas and -thioureas process for their preparation their use as a medicament or diagnostic and medicament containing them

Country Status (32)

Country Link
US (1) US5652268A (pt)
EP (1) EP0727416B1 (pt)
JP (1) JP3905568B2 (pt)
KR (1) KR100450914B1 (pt)
CN (1) CN1058705C (pt)
AR (1) AR003924A1 (pt)
AT (1) ATE189213T1 (pt)
AU (1) AU700793B2 (pt)
BR (1) BR9600778A (pt)
CA (1) CA2169694C (pt)
CY (1) CY2220B1 (pt)
CZ (1) CZ291271B6 (pt)
DE (2) DE19505397A1 (pt)
DK (1) DK0727416T3 (pt)
ES (1) ES2143675T3 (pt)
FI (1) FI120393B (pt)
GR (1) GR3033049T3 (pt)
HK (1) HK1011965A1 (pt)
HR (1) HRP960077B1 (pt)
HU (1) HU226463B1 (pt)
IL (1) IL117150A (pt)
MY (1) MY113431A (pt)
NO (1) NO305751B1 (pt)
NZ (1) NZ280991A (pt)
PL (1) PL181950B1 (pt)
PT (1) PT727416E (pt)
RU (1) RU2198163C2 (pt)
SI (1) SI9600049B (pt)
SK (1) SK281605B6 (pt)
TR (1) TR199600118A2 (pt)
TW (1) TW355183B (pt)
ZA (1) ZA961231B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
DE19647000A1 (de) * 1996-11-14 1998-05-20 Hoechst Ag 3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19832009A1 (de) 1998-07-16 2000-01-20 Hoechst Marion Roussel De Gmbh 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
IL141414A0 (en) * 1998-09-10 2002-03-10 Aventis Pharma Gmbh Use of benzenesulfonyl (thio) ureas for the treatment and prophylaxis of dysfunctions of the autonomous nervous system and use of benzenesulfonyl (thio) ureas in combination with beta-receptor blockers
DE19917233A1 (de) * 1999-04-16 2000-10-19 Aventis Pharma Gmbh Kristalline Formen des Natriumsalzes des 5-Chlor-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonyl-phenyl)-ethyl)- benzamids
DE19923086A1 (de) 1999-05-20 2000-11-23 Aventis Pharma Gmbh Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054482A1 (de) 2000-11-03 2002-05-08 Aventis Pharma Gmbh Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054481A1 (de) 2000-11-03 2002-05-08 Aventis Pharma Gmbh Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
DE102004061017A1 (de) * 2004-12-18 2006-06-22 Sanofi-Aventis Deutschland Gmbh Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
MY148903A (en) * 2007-06-05 2013-06-14 Sanofi Aventis Di(hetero)arylclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them
WO2023020412A1 (zh) * 2021-08-16 2023-02-23 中国科学院上海药物研究所 磺酰脲化合物、制备方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1198354B (de) * 1963-09-25 1965-08-12 Hoechst Ag Verfahren zur Herstellung von Benzol-sulfonylharnstoffen
DE1518874C3 (de) * 1964-10-07 1975-03-13 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
BE754454A (fr) * 1969-08-06 1971-02-05 Bayer Ag Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
DE2413514C3 (de) * 1974-03-21 1982-03-04 Hoechst Ag, 6000 Frankfurt N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung
DK0612724T3 (da) * 1993-02-23 1997-06-16 Hoechst Ag Substituerede benzensulfonylurinstoffer og -thiourinstoffer, fremgangsmåde til deres fremstilling og deres anvendelse som farmaceutika

Also Published As

Publication number Publication date
IL117150A (en) 2001-03-19
HRP960077B1 (en) 2001-06-30
DE59604262D1 (de) 2000-03-02
JPH08245554A (ja) 1996-09-24
CA2169694C (en) 2008-05-20
NO305751B1 (no) 1999-07-19
AR003924A1 (es) 1998-09-30
RU2198163C2 (ru) 2003-02-10
HU9503879D0 (en) 1996-02-28
CZ43696A3 (en) 1996-09-11
FI960689A (fi) 1996-08-18
TR199600118A2 (tr) 1996-10-21
CA2169694A1 (en) 1996-08-18
PL312528A1 (en) 1996-08-19
SI9600049B (en) 2001-12-31
TW355183B (en) 1999-04-01
KR100450914B1 (ko) 2004-12-03
JP3905568B2 (ja) 2007-04-18
CZ291271B6 (cs) 2003-01-15
ATE189213T1 (de) 2000-02-15
CN1058705C (zh) 2000-11-22
HUT73973A (en) 1996-10-28
DK0727416T3 (da) 2000-06-13
ES2143675T3 (es) 2000-05-16
HU226463B1 (en) 2008-12-29
AU700793B2 (en) 1999-01-14
CN1134414A (zh) 1996-10-30
IL117150A0 (en) 1996-06-18
PL181950B1 (pl) 2001-10-31
PT727416E (pt) 2000-06-30
EP0727416A1 (de) 1996-08-21
AU4556096A (en) 1996-08-29
NZ280991A (en) 1997-01-29
EP0727416B1 (de) 2000-01-26
HRP960077A2 (en) 1997-12-31
FI120393B (fi) 2009-10-15
BR9600778A (pt) 1997-12-23
CY2220B1 (en) 2003-04-18
NO960627D0 (no) 1996-02-16
GR3033049T3 (en) 2000-08-31
SK281605B6 (sk) 2001-05-10
FI960689A0 (fi) 1996-02-15
SI9600049A (en) 1996-10-31
HK1011965A1 (en) 1999-07-23
KR960031433A (ko) 1996-09-17
NO960627L (no) 1996-08-19
SK21196A3 (en) 1996-10-02
MY113431A (en) 2002-02-28
DE19505397A1 (de) 1996-08-22
US5652268A (en) 1997-07-29

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