ZA97770B - Substituted diaryldicarboxylic acid diguanidides processes for their preparation their use as a medicament or diagnostic and medicament containing them - Google Patents

Substituted diaryldicarboxylic acid diguanidides processes for their preparation their use as a medicament or diagnostic and medicament containing them

Info

Publication number
ZA97770B
ZA97770B ZA97770A ZA97770A ZA97770B ZA 97770 B ZA97770 B ZA 97770B ZA 97770 A ZA97770 A ZA 97770A ZA 97770 A ZA97770 A ZA 97770A ZA 97770 B ZA97770 B ZA 97770B
Authority
ZA
South Africa
Prior art keywords
medicament
diagnostic
substituted
processes
preparation
Prior art date
Application number
ZA97770A
Inventor
Heinz-Werner Kleemann
Joachim Brendel
Jan-Robert Schwark
Andreas Weichert
Hans Jochen Lang
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA97770B publication Critical patent/ZA97770B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/60—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA97770A 1996-01-31 1997-01-30 Substituted diaryldicarboxylic acid diguanidides processes for their preparation their use as a medicament or diagnostic and medicament containing them ZA97770B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19603425A DE19603425A1 (en) 1996-01-31 1996-01-31 Substituted diaryldicarboxylic acid diguanidides, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them

Publications (1)

Publication Number Publication Date
ZA97770B true ZA97770B (en) 1997-07-31

Family

ID=7784136

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA97770A ZA97770B (en) 1996-01-31 1997-01-30 Substituted diaryldicarboxylic acid diguanidides processes for their preparation their use as a medicament or diagnostic and medicament containing them

Country Status (19)

Country Link
EP (1) EP0787717A1 (en)
JP (1) JPH09221465A (en)
KR (1) KR970059165A (en)
AR (1) AR005596A1 (en)
AU (1) AU1239097A (en)
BR (1) BR9700817A (en)
CA (1) CA2196388A1 (en)
CZ (1) CZ27197A3 (en)
DE (1) DE19603425A1 (en)
HR (1) HRP970057A2 (en)
HU (1) HUP9700277A3 (en)
IL (1) IL120093A0 (en)
NO (1) NO970406L (en)
NZ (1) NZ314145A (en)
PL (1) PL317844A1 (en)
SK (1) SK12797A3 (en)
TR (1) TR199700059A2 (en)
TW (1) TW430642B (en)
ZA (1) ZA97770B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10024319A1 (en) * 2000-05-17 2001-11-22 Merck Patent Gmbh New bis-acylguanidine compounds are subtype-1 cellular sodium ion-proton antiporter inhibitors useful e.g. for treating arrhythmia, angina pectoris, infarction and insulin-independent diabetes mellitus
AR065785A1 (en) * 2007-03-19 2009-07-01 Xenon Pharmaceuticals Inc BIARETO AND BIHETEROARILE COMPOUNDS OF UTILITY IN THE TREATMENT OF IRON DISORDERS

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (en) 1989-09-06 1991-03-07 Hoechst Ag BENZOYLGUANIDINE, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICINE AND THE MEDICINE CONTAINING IT
DK0556674T3 (en) 1992-02-15 1996-10-14 Hoechst Ag 3,5-Substituted benzoylguanidines with antiarrhythmic and inhibitory effect on cell proliferation
US5278933A (en) 1992-06-30 1994-01-11 Hunsinger Terrance D Fiber optic splice organizer and associated method
EP0604852A1 (en) * 1992-12-28 1994-07-06 Hoechst Aktiengesellschaft 2,4-Substituted 5-(N-substituted-sulfamoyl) benzoylguanidines, as antiarrhythmic agents, inhibitors of the proliferation of cells and inhibitors of sodium-hydrogen exchange
IL109570A0 (en) * 1993-05-17 1994-08-26 Fujisawa Pharmaceutical Co Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
DE4327244A1 (en) * 1993-08-13 1995-02-16 Hoechst Ag Urea-substituted benzoyl guanedines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them

Also Published As

Publication number Publication date
TW430642B (en) 2001-04-21
PL317844A1 (en) 1997-08-04
HUP9700277A3 (en) 1998-04-28
NZ314145A (en) 1997-11-24
NO970406D0 (en) 1997-01-30
HUP9700277A2 (en) 1997-10-28
IL120093A0 (en) 1997-04-15
JPH09221465A (en) 1997-08-26
TR199700059A2 (en) 1997-08-21
HRP970057A2 (en) 1998-04-30
EP0787717A1 (en) 1997-08-06
DE19603425A1 (en) 1997-08-07
HU9700277D0 (en) 1997-03-28
CZ27197A3 (en) 1998-05-13
AR005596A1 (en) 1999-06-23
NO970406L (en) 1997-08-01
KR970059165A (en) 1997-08-12
CA2196388A1 (en) 1997-08-01
SK12797A3 (en) 1998-02-04
AU1239097A (en) 1997-08-07
BR9700817A (en) 1998-07-07

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