ZA959215B - Substituted tetracyclic azepine derivatives - Google Patents

Substituted tetracyclic azepine derivatives

Info

Publication number
ZA959215B
ZA959215B ZA959215A ZA959215A ZA959215B ZA 959215 B ZA959215 B ZA 959215B ZA 959215 A ZA959215 A ZA 959215A ZA 959215 A ZA959215 A ZA 959215A ZA 959215 B ZA959215 B ZA 959215B
Authority
ZA
South Africa
Prior art keywords
substituted tetracyclic
azepine derivatives
tetracyclic azepine
derivatives
substituted
Prior art date
Application number
ZA959215A
Other languages
English (en)
Inventor
Victor Karel Sipido
Francisco Javi Fernandez-Gadea
Jose Ignacio Andres-Gil
Theo Frans Meert
Pilar Gil-Lopetegui
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA959215B publication Critical patent/ZA959215B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA959215A 1994-11-02 1995-10-31 Substituted tetracyclic azepine derivatives ZA959215B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94203178 1994-11-02

Publications (1)

Publication Number Publication Date
ZA959215B true ZA959215B (en) 1997-04-30

Family

ID=8217337

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA959215A ZA959215B (en) 1994-11-02 1995-10-31 Substituted tetracyclic azepine derivatives

Country Status (30)

Country Link
US (1) US5552399A (hr)
EP (1) EP0789701B1 (hr)
JP (1) JP3818541B2 (hr)
KR (1) KR100392060B1 (hr)
CN (1) CN1085667C (hr)
AR (1) AR002238A1 (hr)
AT (1) ATE199087T1 (hr)
AU (1) AU704285B2 (hr)
BR (1) BR9509552A (hr)
CA (1) CA2203661A1 (hr)
CZ (1) CZ286945B6 (hr)
DE (1) DE69520070T2 (hr)
DK (1) DK0789701T3 (hr)
ES (1) ES2155898T3 (hr)
FI (1) FI113050B (hr)
GR (1) GR3035680T3 (hr)
HR (1) HRP950537A2 (hr)
HU (1) HUT77408A (hr)
IL (1) IL115819A (hr)
MY (1) MY113325A (hr)
NO (1) NO308035B1 (hr)
NZ (1) NZ295656A (hr)
PL (1) PL183686B1 (hr)
PT (1) PT789701E (hr)
RU (1) RU2163240C2 (hr)
SI (1) SI0789701T1 (hr)
TR (1) TR199501356A2 (hr)
TW (1) TW349950B (hr)
WO (1) WO1996014320A1 (hr)
ZA (1) ZA959215B (hr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ329954A (en) * 1996-04-12 1999-07-29 Janssen Pharmaceutica Nv Isoxazolidine tetracyclic and tricyclic ring system derivatives and medicaments
UA52778C2 (uk) * 1997-10-10 2003-01-15 Янссен Фармацевтика Н.В. Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
HRP20020305A8 (hr) 2002-04-10 2009-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 2-tia-dibenzoazuleni kao inhibitori produkcije faktora nekroze tumora i međuprodukti za njihovu pripravu
HRP20030885A2 (en) * 2003-11-03 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 2-THIA-DIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYYTEM DISEASES AND DISORDERS
HRP20030953A2 (en) * 2003-11-21 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. PREPARATION OF 1-AZA-2-OXA-DIBENZO[e,h]AZULENES AND THEIR USE FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
CA3069699A1 (en) * 2017-07-13 2019-01-17 Tonix Pharmaceuticals Holding Corp. Analogs of cyclobenzaprine and amitryptilene

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
NL7414038A (nl) * 1974-10-28 1976-05-03 Akzo Nv Nieuwe tetracyclische pyrrolidino derivaten.
DE2647114A1 (de) * 1975-10-21 1977-05-05 Hans Fickler Vorrichtung zur erzeugung einer laengsbewegung
JPS5572177A (en) * 1978-11-27 1980-05-30 Shionogi & Co Ltd 4,1-benzoxazepine or 4,1-benzothiazepine
RU2048469C1 (ru) * 1989-10-05 1995-11-20 Санкио Компани Лимитед Способ получения азетидинового производного или его фармацевтически приемлемой соли
US5512563A (en) * 1993-07-29 1996-04-30 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists

Also Published As

Publication number Publication date
GR3035680T3 (en) 2001-06-29
CA2203661A1 (en) 1996-05-17
MY113325A (en) 2002-01-31
CZ286945B6 (en) 2000-08-16
KR100392060B1 (ko) 2003-11-28
NO308035B1 (no) 2000-07-10
ATE199087T1 (de) 2001-02-15
EP0789701B1 (en) 2001-02-07
DK0789701T3 (da) 2001-06-18
HRP950537A2 (en) 1997-08-31
US5552399A (en) 1996-09-03
WO1996014320A1 (en) 1996-05-17
IL115819A0 (en) 1996-01-19
FI971854A (fi) 1997-04-30
AR002238A1 (es) 1998-03-11
RU2163240C2 (ru) 2001-02-20
FI113050B (fi) 2004-02-27
AU704285B2 (en) 1999-04-15
CN1085667C (zh) 2002-05-29
PL183686B1 (pl) 2002-06-28
PT789701E (pt) 2001-07-31
JP3818541B2 (ja) 2006-09-06
DE69520070D1 (de) 2001-03-15
CN1162313A (zh) 1997-10-15
TR199501356A2 (tr) 1996-06-21
JPH10508308A (ja) 1998-08-18
ES2155898T3 (es) 2001-06-01
HUT77408A (hu) 1998-04-28
TW349950B (en) 1999-01-11
PL319939A1 (en) 1997-09-01
NO972017L (no) 1997-04-30
IL115819A (en) 1998-10-30
CZ132397A3 (cs) 1998-01-14
MX9703255A (es) 1997-07-31
NZ295656A (en) 1998-10-28
NO972017D0 (no) 1997-04-30
BR9509552A (pt) 1997-09-16
EP0789701A1 (en) 1997-08-20
AU3924995A (en) 1996-05-31
SI0789701T1 (en) 2001-08-31
DE69520070T2 (de) 2001-09-13
FI971854A0 (fi) 1997-04-30

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