NO972017D0 - Substituerte tetracykliske azepinderivater som har affinitet for 5-HT2 -reseptorer - Google Patents

Substituerte tetracykliske azepinderivater som har affinitet for 5-HT2 -reseptorer

Info

Publication number
NO972017D0
NO972017D0 NO972017A NO972017A NO972017D0 NO 972017 D0 NO972017 D0 NO 972017D0 NO 972017 A NO972017 A NO 972017A NO 972017 A NO972017 A NO 972017A NO 972017 D0 NO972017 D0 NO 972017D0
Authority
NO
Norway
Prior art keywords
receptors
affinity
substituted tetracyclic
azepine derivatives
tetracyclic azepine
Prior art date
Application number
NO972017A
Other languages
English (en)
Other versions
NO972017L (no
NO308035B1 (no
Inventor
Victor Karel Sipido
Francisco Javi Fernandez-Gadea
Jose Ignacio Andres-Gil
Theo Frans Meert
Pilar Gil-Lopetegui
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO972017D0 publication Critical patent/NO972017D0/no
Publication of NO972017L publication Critical patent/NO972017L/no
Publication of NO308035B1 publication Critical patent/NO308035B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO972017A 1994-11-02 1997-04-30 Substituerte tetracykliske azepinderivater som har affinitet for 5-HT2-reseptorer NO308035B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94203178 1994-11-02
US08/457,968 US5552399A (en) 1994-11-02 1995-05-31 Substituted tetracyclic azepine derivatives
PCT/EP1995/004196 WO1996014320A1 (en) 1994-11-02 1995-10-25 Substituted tetracyclic azepine derivatives which have affinity for 5-ht2 receptors

Publications (3)

Publication Number Publication Date
NO972017D0 true NO972017D0 (no) 1997-04-30
NO972017L NO972017L (no) 1997-04-30
NO308035B1 NO308035B1 (no) 2000-07-10

Family

ID=8217337

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972017A NO308035B1 (no) 1994-11-02 1997-04-30 Substituerte tetracykliske azepinderivater som har affinitet for 5-HT2-reseptorer

Country Status (30)

Country Link
US (1) US5552399A (no)
EP (1) EP0789701B1 (no)
JP (1) JP3818541B2 (no)
KR (1) KR100392060B1 (no)
CN (1) CN1085667C (no)
AR (1) AR002238A1 (no)
AT (1) ATE199087T1 (no)
AU (1) AU704285B2 (no)
BR (1) BR9509552A (no)
CA (1) CA2203661A1 (no)
CZ (1) CZ286945B6 (no)
DE (1) DE69520070T2 (no)
DK (1) DK0789701T3 (no)
ES (1) ES2155898T3 (no)
FI (1) FI113050B (no)
GR (1) GR3035680T3 (no)
HR (1) HRP950537A2 (no)
HU (1) HUT77408A (no)
IL (1) IL115819A (no)
MY (1) MY113325A (no)
NO (1) NO308035B1 (no)
NZ (1) NZ295656A (no)
PL (1) PL183686B1 (no)
PT (1) PT789701E (no)
RU (1) RU2163240C2 (no)
SI (1) SI0789701T1 (no)
TR (1) TR199501356A2 (no)
TW (1) TW349950B (no)
WO (1) WO1996014320A1 (no)
ZA (1) ZA959215B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0892804T3 (da) * 1996-04-12 2002-12-02 Janssen Pharmaceutica Nv Isoxazolidin derivater
UA52778C2 (uk) * 1997-10-10 2003-01-15 Янссен Фармацевтика Н.В. Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
HRP20020305A8 (en) 2002-04-10 2009-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20030885A2 (en) * 2003-11-03 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 2-THIA-DIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYYTEM DISEASES AND DISORDERS
HRP20030953A2 (en) * 2003-11-21 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. PREPARATION OF 1-AZA-2-OXA-DIBENZO[e,h]AZULENES AND THEIR USE FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
US20110086086A1 (en) * 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
WO2019014651A1 (en) * 2017-07-13 2019-01-17 Tonix Pharmaceuticals Holding Corp. ANALOGUES OF CYCLOBENZAPRINE AND AMITRYPTILENE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
NL7414038A (nl) * 1974-10-28 1976-05-03 Akzo Nv Nieuwe tetracyclische pyrrolidino derivaten.
DE2647114A1 (de) * 1975-10-21 1977-05-05 Hans Fickler Vorrichtung zur erzeugung einer laengsbewegung
JPS5572177A (en) * 1978-11-27 1980-05-30 Shionogi & Co Ltd 4,1-benzoxazepine or 4,1-benzothiazepine
CA2026925A1 (en) * 1989-10-05 1991-04-06 Hiroshi Fukumi Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
US5512563A (en) * 1993-07-29 1996-04-30 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists

Also Published As

Publication number Publication date
CA2203661A1 (en) 1996-05-17
DE69520070D1 (de) 2001-03-15
JPH10508308A (ja) 1998-08-18
CZ286945B6 (en) 2000-08-16
CN1162313A (zh) 1997-10-15
BR9509552A (pt) 1997-09-16
FI971854A7 (fi) 1997-04-30
AR002238A1 (es) 1998-03-11
ZA959215B (en) 1997-04-30
ES2155898T3 (es) 2001-06-01
PL319939A1 (en) 1997-09-01
PL183686B1 (pl) 2002-06-28
MX9703255A (es) 1997-07-31
NZ295656A (en) 1998-10-28
AU3924995A (en) 1996-05-31
HRP950537A2 (en) 1997-08-31
HUT77408A (hu) 1998-04-28
CZ132397A3 (cs) 1998-01-14
NO972017L (no) 1997-04-30
AU704285B2 (en) 1999-04-15
CN1085667C (zh) 2002-05-29
MY113325A (en) 2002-01-31
FI971854A0 (fi) 1997-04-30
KR100392060B1 (ko) 2003-11-28
DE69520070T2 (de) 2001-09-13
GR3035680T3 (en) 2001-06-29
JP3818541B2 (ja) 2006-09-06
ATE199087T1 (de) 2001-02-15
IL115819A0 (en) 1996-01-19
SI0789701T1 (en) 2001-08-31
PT789701E (pt) 2001-07-31
WO1996014320A1 (en) 1996-05-17
NO308035B1 (no) 2000-07-10
EP0789701A1 (en) 1997-08-20
DK0789701T3 (da) 2001-06-18
EP0789701B1 (en) 2001-02-07
FI113050B (fi) 2004-02-27
TR199501356A2 (tr) 1996-06-21
RU2163240C2 (ru) 2001-02-20
US5552399A (en) 1996-09-03
IL115819A (en) 1998-10-30
TW349950B (en) 1999-01-11

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