ZA93974B - N,N' substituted imidodicarbonimidic diamides derived from hydroxylamines. - Google Patents

N,N' substituted imidodicarbonimidic diamides derived from hydroxylamines.

Info

Publication number
ZA93974B
ZA93974B ZA93974A ZA93974A ZA93974B ZA 93974 B ZA93974 B ZA 93974B ZA 93974 A ZA93974 A ZA 93974A ZA 93974 A ZA93974 A ZA 93974A ZA 93974 B ZA93974 B ZA 93974B
Authority
ZA
South Africa
Prior art keywords
group
carbon atoms
mono
substituted
salts
Prior art date
Application number
ZA93974A
Other languages
English (en)
Inventor
Craig Canfield
David P Jacobus
Neil J Lewis
Original Assignee
Jacobus Pharmaceutical Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jacobus Pharmaceutical Company filed Critical Jacobus Pharmaceutical Company
Publication of ZA93974B publication Critical patent/ZA93974B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/13—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paints Or Removers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Detergent Compositions (AREA)
  • Luminescent Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Seasonings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA93974A 1992-02-14 1993-02-12 N,N' substituted imidodicarbonimidic diamides derived from hydroxylamines. ZA93974B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/837,258 US5322858A (en) 1992-02-14 1992-02-14 N,N'-substituted imidodicarbonimidic diamides derived from hydroxylamines

Publications (1)

Publication Number Publication Date
ZA93974B true ZA93974B (en) 1993-09-14

Family

ID=25273975

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA93974A ZA93974B (en) 1992-02-14 1993-02-12 N,N' substituted imidodicarbonimidic diamides derived from hydroxylamines.

Country Status (25)

Country Link
US (1) US5322858A (xx)
EP (1) EP0625967B1 (xx)
JP (1) JP3207200B2 (xx)
KR (1) KR950700243A (xx)
CN (1) CN1057520C (xx)
AT (1) ATE157352T1 (xx)
AU (1) AU668709B2 (xx)
CA (1) CA2129430C (xx)
CZ (1) CZ294257B6 (xx)
DE (1) DE69313438T2 (xx)
DK (1) DK0625967T3 (xx)
EG (1) EG20476A (xx)
ES (1) ES2108862T3 (xx)
FI (1) FI943738A (xx)
GR (1) GR3025429T3 (xx)
HU (1) HU220389B (xx)
IL (1) IL104484A (xx)
MX (1) MX9300688A (xx)
NO (1) NO302616B1 (xx)
NZ (1) NZ245865A (xx)
OA (1) OA10094A (xx)
PL (2) PL172001B1 (xx)
RU (1) RU2133737C1 (xx)
WO (1) WO1993016037A1 (xx)
ZA (1) ZA93974B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4321444A1 (de) * 1993-06-28 1995-01-05 Bernd Prof Dr Clement Pharmazeutische Zubereitung
US6551614B2 (en) 2001-03-14 2003-04-22 Jacobus Pharmaceutical Co., Inc. Antimalarial N,N′-substituted biguanides derived from hydroxylamines
AU2003220222A1 (en) 2002-03-13 2003-09-29 Signum Biosciences, Inc. Modulation of protein methylation and phosphoprotein phosphate
US7256218B2 (en) * 2002-11-22 2007-08-14 Jacobus Pharmaceutical Company, Inc. Biguanide and dihydrotriazine derivatives
CN1738794B (zh) * 2002-11-22 2010-12-22 雅各布斯制药公司 双胍和二氢三嗪衍生物
WO2006084033A1 (en) * 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
KR101578949B1 (ko) 2007-10-08 2015-12-18 엠엠브이 메디슨즈 포 말라리아 벤처 가요성 측쇄를 가지는 항말라리아 화합물
MX2010003972A (es) * 2007-10-13 2010-08-09 Univ Cornell Composiciones para producir una respuesta inmune contra para-tuberculosis sub-especie mycobacterium avium.
EP2282735B1 (en) 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulators for treating alzheimer, parkinson, diabetes
EP2273974A2 (en) * 2008-05-09 2011-01-19 Tolmar, Inc. Proguanil to treat skin/mucosal diseases
US10829440B2 (en) 2015-06-12 2020-11-10 Brown University Antibacterial compounds and methods of making and using same
WO2018106907A1 (en) * 2016-12-08 2018-06-14 Novatarg, Inc. Fused bicyclic alkylene linked imidodicarbonimidic diamides, methods for synthesis, and uses in therary
US11555010B2 (en) 2019-07-25 2023-01-17 Brown University Diamide antimicrobial agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB603070A (en) * 1946-01-25 1948-06-08 Albert Frederick Crowther Manufacture of biguanide derivatives
GB665680A (en) * 1948-02-20 1952-01-30 Rhone Poulenc Sa Improvements in or relating to the production of n-p-chlorophenyl-n-isopropyl biguanide
DE824942C (de) * 1949-01-31 1951-12-17 Ici Ltd Verfahren zur Herstellung von Biguanidderivaten
GB667116A (en) * 1949-04-25 1952-02-27 Albert Frederick Crowther Manufacture of biguanide derivatives
GB814563A (en) * 1956-11-15 1959-06-10 Vitamins Ltd Biguanides
GB1270831A (en) * 1968-11-22 1972-04-19 Beecham Group Ltd Di-hydro triazine derivatives and processes for their manufacture
GB1250531A (xx) * 1969-01-01 1971-10-20
US3723429A (en) * 1969-11-06 1973-03-27 Beecham Group Ltd Di-hydro triazine derivatives
US3660394A (en) * 1970-01-23 1972-05-02 Vitamins Ltd 4 6-dibenzo-1 2-dihydro-aryloxy-1 3 5-triazines

Also Published As

Publication number Publication date
CN1076689A (zh) 1993-09-29
JPH07503730A (ja) 1995-04-20
HUT68802A (en) 1995-07-28
CA2129430A1 (en) 1993-08-15
MX9300688A (es) 1993-08-01
ATE157352T1 (de) 1997-09-15
HU220389B (hu) 2002-01-28
DE69313438D1 (de) 1997-10-02
KR950700243A (ko) 1995-01-16
CA2129430C (en) 2004-04-06
NZ245865A (en) 1996-02-27
JP3207200B2 (ja) 2001-09-10
PL172001B1 (pl) 1997-07-31
ES2108862T3 (es) 1998-01-01
FI943738A0 (fi) 1994-08-12
US5322858A (en) 1994-06-21
CZ196494A3 (en) 1995-10-18
PL173258B1 (pl) 1998-02-27
EG20476A (en) 1999-05-31
NO302616B1 (no) 1998-03-30
CZ294257B6 (cs) 2004-11-10
RU94039539A (ru) 1997-05-27
WO1993016037A1 (en) 1993-08-19
IL104484A0 (en) 1993-05-13
EP0625967B1 (en) 1997-08-27
DK0625967T3 (da) 1998-03-23
IL104484A (en) 1998-07-15
NO942988L (no) 1994-10-05
EP0625967A1 (en) 1994-11-30
DE69313438T2 (de) 1998-03-19
NO942988D0 (no) 1994-08-12
AU3475993A (en) 1993-09-03
FI943738A (fi) 1994-10-12
GR3025429T3 (en) 1998-02-27
CN1057520C (zh) 2000-10-18
HU9401976D0 (en) 1994-09-28
AU668709B2 (en) 1996-05-16
RU2133737C1 (ru) 1999-07-27
OA10094A (en) 1996-12-18

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