ZA936394B - Monohydrate of 5-(2-(4-(1,2 benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one hydrochioride - Google Patents

Monohydrate of 5-(2-(4-(1,2 benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one hydrochioride

Info

Publication number
ZA936394B
ZA936394B ZA936394A ZA936394A ZA936394B ZA 936394 B ZA936394 B ZA 936394B ZA 936394 A ZA936394 A ZA 936394A ZA 936394 A ZA936394 A ZA 936394A ZA 936394 B ZA936394 B ZA 936394B
Authority
ZA
South Africa
Prior art keywords
hydrochioride
benzisothiazol
indol
piperazinyl
monohydrate
Prior art date
Application number
ZA936394A
Other languages
English (en)
Inventor
Douglas J M Allen
Frank R Busch
Sabeto A Diroma
Dennis M Godek
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA936394B publication Critical patent/ZA936394B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA936394A 1992-09-01 1993-08-31 Monohydrate of 5-(2-(4-(1,2 benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one hydrochioride ZA936394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/939,204 US5312925A (en) 1992-09-01 1992-09-01 Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride

Publications (1)

Publication Number Publication Date
ZA936394B true ZA936394B (en) 1995-02-28

Family

ID=25472737

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA936394A ZA936394B (en) 1992-09-01 1993-08-31 Monohydrate of 5-(2-(4-(1,2 benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one hydrochioride

Country Status (21)

Country Link
US (1) US5312925A (pt)
EP (1) EP0586191A1 (pt)
JP (1) JP2742372B2 (pt)
KR (2) KR100278321B1 (pt)
CN (1) CN1033641C (pt)
AU (1) AU657231B2 (pt)
BR (1) BR9303014A (pt)
CA (1) CA2105114C (pt)
CZ (1) CZ285984B6 (pt)
DE (1) DE9312903U1 (pt)
EG (1) EG20251A (pt)
FI (1) FI115460B (pt)
HU (1) HU221725B1 (pt)
IL (1) IL106777A (pt)
MX (1) MX9305277A (pt)
NO (1) NO300270B1 (pt)
NZ (1) NZ248543A (pt)
PL (2) PL174396B1 (pt)
RU (1) RU2081116C1 (pt)
TW (1) TW422845B (pt)
ZA (1) ZA936394B (pt)

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US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
JPH0686253B2 (ja) * 1992-01-28 1994-11-02 株式会社日立東サービスエンジニアリング フレキシブルコンテナ収納体
IT1255263B (it) * 1992-04-02 1995-10-25 Metodo e composizione liquida per la realizzazione di scritte indelebili su un substrato cartaceo
DE69322707T2 (de) * 1992-07-31 1999-08-19 Bristol-Myers Squibb Company Diphenyl Oxazole-, Thiazole- und Imidazole-Derivate als Inhibitoren der Wiederaufnahme des Adenosins

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US5312925A (en) 1994-05-17
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FI933804A (fi) 1994-03-02
RU2081116C1 (ru) 1997-06-10
CN1033641C (zh) 1996-12-25
NO300270B1 (no) 1997-05-05
JPH06157521A (ja) 1994-06-03
CA2105114A1 (en) 1994-03-02
PL173967B1 (pl) 1998-05-29
IL106777A (en) 1997-04-15
NO933093L (no) 1994-03-02
NO933093D0 (no) 1993-08-31
AU4600493A (en) 1994-06-16
KR940007025A (ko) 1994-04-26
PL300235A1 (en) 1994-04-05
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HU221725B1 (hu) 2002-12-28
CA2105114C (en) 2000-02-15
JP2742372B2 (ja) 1998-04-22
TW422845B (en) 2001-02-21
BR9303014A (pt) 1994-03-15
CZ285984B6 (cs) 1999-12-15
KR100278321B1 (ko) 2001-01-15
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