ZA926939B - Antimuscarinic bronchodilators - Google Patents

Antimuscarinic bronchodilators

Info

Publication number
ZA926939B
ZA926939B ZA926939A ZA926939A ZA926939B ZA 926939 B ZA926939 B ZA 926939B ZA 926939 A ZA926939 A ZA 926939A ZA 926939 A ZA926939 A ZA 926939A ZA 926939 B ZA926939 B ZA 926939B
Authority
ZA
South Africa
Prior art keywords
pct
alkyl
image
sec
optionally substituted
Prior art date
Application number
ZA926939A
Other languages
English (en)
Inventor
Peter Edward Cross
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA926939B publication Critical patent/ZA926939B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ZA926939A 1991-09-14 1992-09-11 Antimuscarinic bronchodilators ZA926939B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919119705A GB9119705D0 (en) 1991-09-14 1991-09-14 Therapeutic compounds

Publications (1)

Publication Number Publication Date
ZA926939B true ZA926939B (en) 1994-03-11

Family

ID=10701448

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA926939A ZA926939B (en) 1991-09-14 1992-09-11 Antimuscarinic bronchodilators

Country Status (31)

Country Link
US (1) US5543419A (ru)
EP (1) EP0603229B1 (ru)
JP (2) JP2672030B2 (ru)
KR (1) KR0135784B1 (ru)
CN (1) CN1037269C (ru)
AT (1) ATE167187T1 (ru)
AU (1) AU659487B2 (ru)
BR (1) BR9206499A (ru)
CA (1) CA2116356C (ru)
CZ (1) CZ281752B6 (ru)
DE (1) DE69225897T2 (ru)
DK (1) DK0603229T3 (ru)
EG (1) EG20072A (ru)
ES (1) ES2116343T3 (ru)
FI (1) FI114707B (ru)
GB (1) GB9119705D0 (ru)
GR (1) GR3027667T3 (ru)
HU (1) HU220594B1 (ru)
IL (1) IL103078A (ru)
MX (1) MX9205221A (ru)
MY (1) MY108602A (ru)
NO (1) NO305397B1 (ru)
NZ (1) NZ244324A (ru)
PL (1) PL170627B1 (ru)
PT (1) PT100863B (ru)
RU (1) RU2117669C1 (ru)
SG (1) SG50414A1 (ru)
TW (1) TW251285B (ru)
UA (1) UA42686C2 (ru)
WO (1) WO1993006098A1 (ru)
ZA (1) ZA926939B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE194342T1 (de) 1996-01-19 2000-07-15 Lonza Ag Verfahren zur herstellung von optisch aktivem 3- chinuclidinol
CZ54498A3 (cs) * 1997-03-07 1998-11-11 Lonza Ag Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití
JP2001513495A (ja) * 1997-08-08 2001-09-04 デューク ユニバーシティ 外科的処置を容易にする組成物、装置および方法
US6711436B1 (en) 1997-08-08 2004-03-23 Duke University Compositions, apparatus and methods for facilitating surgical procedures
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
DK1345937T3 (da) 2000-12-22 2006-01-16 Almirall Prodesfarma Ag Quinuclidincarbamatderivater og deres anvendelse som M3-antagonister
CZ301209B6 (cs) 2000-12-28 2009-12-09 Laboratorios Almirall, S.A. Nové chinuklidinové deriváty a medicinální kompozice s jejich obsahem
DE102004057995A1 (de) * 2004-12-01 2006-06-08 Wacker Chemie Ag Verfahren zur Herstellung von α,α-Dialkyl-α-Hydroxymethyl-Carbonsäurederivaten
US20100112061A1 (en) * 2006-12-13 2010-05-06 William Baker Monophosphates as Mutual Prodrugs of Muscarinic Receptor Antagonists and Beta-Agonists for the Treatment of COPD And Chronic Bronchitis
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
GB8923590D0 (en) * 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators

Also Published As

Publication number Publication date
RU2117669C1 (ru) 1998-08-20
DK0603229T3 (da) 1998-10-12
JP2955533B2 (ja) 1999-10-04
GB9119705D0 (en) 1991-10-30
MX9205221A (es) 1993-03-01
DE69225897T2 (de) 1998-10-15
FI941170A0 (fi) 1994-03-11
CZ281752B6 (cs) 1997-01-15
EG20072A (en) 1999-06-30
TW251285B (ru) 1995-07-11
NO940905D0 (no) 1994-03-14
PT100863A (pt) 1993-10-29
SG50414A1 (en) 1998-07-20
EP0603229B1 (en) 1998-06-10
UA42686C2 (ru) 2001-11-15
JPH09315970A (ja) 1997-12-09
AU659487B2 (en) 1995-05-18
WO1993006098A1 (en) 1993-04-01
HUT66772A (en) 1994-12-28
FI114707B (fi) 2004-12-15
CN1037269C (zh) 1998-02-04
CZ395392A3 (en) 1994-07-13
HU220594B1 (hu) 2002-03-28
JP2672030B2 (ja) 1997-11-05
IL103078A (en) 1996-07-23
HU9400729D0 (en) 1994-06-28
KR0135784B1 (ko) 1998-04-23
FI941170A (fi) 1994-03-11
IL103078A0 (en) 1993-02-21
CA2116356A1 (en) 1993-04-01
CN1070911A (zh) 1993-04-14
DE69225897D1 (de) 1998-07-16
US5543419A (en) 1996-08-06
BR9206499A (pt) 1995-11-21
EP0603229A1 (en) 1994-06-29
PT100863B (pt) 1999-07-30
NO940905L (no) 1994-03-14
JPH06510991A (ja) 1994-12-08
GR3027667T3 (en) 1998-11-30
AU2482392A (en) 1993-04-27
ATE167187T1 (de) 1998-06-15
MY108602A (en) 1996-10-31
NZ244324A (en) 1993-12-23
ES2116343T3 (es) 1998-07-16
NO305397B1 (no) 1999-05-25
PL170627B1 (en) 1997-01-31
CA2116356C (en) 1998-03-31

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