NO940905L - Kinuklidinesterprosess og mellomprodukter ved fremstilling av kinuklidinestere og farmasöytiske sammensetninger inneholdende dem - Google Patents
Kinuklidinesterprosess og mellomprodukter ved fremstilling av kinuklidinestere og farmasöytiske sammensetninger inneholdende demInfo
- Publication number
- NO940905L NO940905L NO940905A NO940905A NO940905L NO 940905 L NO940905 L NO 940905L NO 940905 A NO940905 A NO 940905A NO 940905 A NO940905 A NO 940905A NO 940905 L NO940905 L NO 940905L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- kinuclidine
- intermediates
- preparation
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919119705A GB9119705D0 (en) | 1991-09-14 | 1991-09-14 | Therapeutic compounds |
| PCT/EP1992/002067 WO1993006098A1 (en) | 1991-09-14 | 1992-09-03 | Quinuclidine esters process and intermediate for their preparation and pharmaceutical compositions containing them |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO940905D0 NO940905D0 (no) | 1994-03-14 |
| NO940905L true NO940905L (no) | 1994-03-14 |
| NO305397B1 NO305397B1 (no) | 1999-05-25 |
Family
ID=10701448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940905A NO305397B1 (no) | 1991-09-14 | 1994-03-14 | Kinuklidinesterprosess og mellomprodukter ved fremstilling av kinuklidinestere og farmas°ytiske sammensetninger inneholdende dem |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5543419A (no) |
| EP (1) | EP0603229B1 (no) |
| JP (2) | JP2672030B2 (no) |
| KR (1) | KR0135784B1 (no) |
| CN (1) | CN1037269C (no) |
| AT (1) | ATE167187T1 (no) |
| AU (1) | AU659487B2 (no) |
| BR (1) | BR9206499A (no) |
| CA (1) | CA2116356C (no) |
| CZ (1) | CZ281752B6 (no) |
| DE (1) | DE69225897T2 (no) |
| DK (1) | DK0603229T3 (no) |
| EG (1) | EG20072A (no) |
| ES (1) | ES2116343T3 (no) |
| FI (1) | FI114707B (no) |
| GB (1) | GB9119705D0 (no) |
| GR (1) | GR3027667T3 (no) |
| HU (1) | HU220594B1 (no) |
| IL (1) | IL103078A (no) |
| MX (1) | MX9205221A (no) |
| MY (1) | MY108602A (no) |
| NO (1) | NO305397B1 (no) |
| NZ (1) | NZ244324A (no) |
| PL (1) | PL170627B1 (no) |
| PT (1) | PT100863B (no) |
| RU (1) | RU2117669C1 (no) |
| SG (1) | SG50414A1 (no) |
| TW (1) | TW251285B (no) |
| UA (1) | UA42686C2 (no) |
| WO (1) | WO1993006098A1 (no) |
| ZA (1) | ZA926939B (no) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE194342T1 (de) * | 1996-01-19 | 2000-07-15 | Lonza Ag | Verfahren zur herstellung von optisch aktivem 3- chinuclidinol |
| CZ54498A3 (cs) * | 1997-03-07 | 1998-11-11 | Lonza Ag | Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití |
| JP2001513495A (ja) | 1997-08-08 | 2001-09-04 | デューク ユニバーシティ | 外科的処置を容易にする組成物、装置および方法 |
| US6711436B1 (en) | 1997-08-08 | 2004-03-23 | Duke University | Compositions, apparatus and methods for facilitating surgical procedures |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| SK8002003A3 (en) | 2000-12-22 | 2004-05-04 | Almirall Prodesfarma Ag | Quinuclidine carbamate derivatives and their use as M3 antagonists |
| AU2002238471B2 (en) | 2000-12-28 | 2007-06-28 | Almirall, S.A. | Quinuclidine derivatives and their use as M3 antagonists |
| DE102004057995A1 (de) * | 2004-12-01 | 2006-06-08 | Wacker Chemie Ag | Verfahren zur Herstellung von α,α-Dialkyl-α-Hydroxymethyl-Carbonsäurederivaten |
| US20100112061A1 (en) * | 2006-12-13 | 2010-05-06 | William Baker | Monophosphates as Mutual Prodrugs of Muscarinic Receptor Antagonists and Beta-Agonists for the Treatment of COPD And Chronic Bronchitis |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4843074A (en) * | 1988-05-17 | 1989-06-27 | Marion Laboratories, Inc. | 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts |
| GB8923590D0 (en) * | 1989-10-19 | 1989-12-06 | Pfizer Ltd | Antimuscarinic bronchodilators |
-
1991
- 1991-09-14 GB GB919119705A patent/GB9119705D0/en active Pending
-
1992
- 1992-09-03 US US08/204,260 patent/US5543419A/en not_active Expired - Fee Related
- 1992-09-03 AT AT92918526T patent/ATE167187T1/de not_active IP Right Cessation
- 1992-09-03 UA UA94005520A patent/UA42686C2/uk unknown
- 1992-09-03 PL PL92302771A patent/PL170627B1/pl unknown
- 1992-09-03 ES ES92918526T patent/ES2116343T3/es not_active Expired - Lifetime
- 1992-09-03 HU HU9400729A patent/HU220594B1/hu not_active IP Right Cessation
- 1992-09-03 AU AU24823/92A patent/AU659487B2/en not_active Ceased
- 1992-09-03 CZ CS923953A patent/CZ281752B6/cs not_active IP Right Cessation
- 1992-09-03 WO PCT/EP1992/002067 patent/WO1993006098A1/en active IP Right Grant
- 1992-09-03 RU RU94019411/04A patent/RU2117669C1/ru not_active IP Right Cessation
- 1992-09-03 JP JP5505734A patent/JP2672030B2/ja not_active Expired - Fee Related
- 1992-09-03 SG SG1996000871A patent/SG50414A1/en unknown
- 1992-09-03 EP EP92918526A patent/EP0603229B1/en not_active Expired - Lifetime
- 1992-09-03 DE DE69225897T patent/DE69225897T2/de not_active Expired - Fee Related
- 1992-09-03 DK DK92918526T patent/DK0603229T3/da active
- 1992-09-03 BR BR9206499A patent/BR9206499A/pt not_active Application Discontinuation
- 1992-09-03 KR KR1019940700816A patent/KR0135784B1/ko not_active IP Right Cessation
- 1992-09-03 CA CA002116356A patent/CA2116356C/en not_active Expired - Fee Related
- 1992-09-07 IL IL10307892A patent/IL103078A/en not_active IP Right Cessation
- 1992-09-10 TW TW081107184A patent/TW251285B/zh active
- 1992-09-11 PT PT100863A patent/PT100863B/pt active IP Right Grant
- 1992-09-11 ZA ZA926939A patent/ZA926939B/xx unknown
- 1992-09-11 MX MX9205221A patent/MX9205221A/es not_active IP Right Cessation
- 1992-09-14 CN CN92110746A patent/CN1037269C/zh not_active Expired - Fee Related
- 1992-09-14 MY MYPI92001642A patent/MY108602A/en unknown
- 1992-09-14 EG EG54292A patent/EG20072A/xx active
- 1992-09-14 NZ NZ244324A patent/NZ244324A/en unknown
-
1994
- 1994-03-11 FI FI941170A patent/FI114707B/fi not_active IP Right Cessation
- 1994-03-14 NO NO940905A patent/NO305397B1/no unknown
-
1997
- 1997-02-18 JP JP9033807A patent/JP2955533B2/ja not_active Expired - Fee Related
-
1998
- 1998-08-19 GR GR980401846T patent/GR3027667T3/el unknown
Also Published As
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