FI941170A0 - Kinuklidiiniestereitä, menetelmä ja välituote niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia - Google Patents

Kinuklidiiniestereitä, menetelmä ja välituote niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia

Info

Publication number
FI941170A0
FI941170A0 FI941170A FI941170A FI941170A0 FI 941170 A0 FI941170 A0 FI 941170A0 FI 941170 A FI941170 A FI 941170A FI 941170 A FI941170 A FI 941170A FI 941170 A0 FI941170 A0 FI 941170A0
Authority
FI
Finland
Prior art keywords
pct
alkyl
image
preparation
pharmaceutical compositions
Prior art date
Application number
FI941170A
Other languages
English (en)
Swedish (sv)
Other versions
FI114707B (fi
FI941170A (fi
Inventor
Peter Edward Cross
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI941170A0 publication Critical patent/FI941170A0/fi
Publication of FI941170A publication Critical patent/FI941170A/fi
Application granted granted Critical
Publication of FI114707B publication Critical patent/FI114707B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI941170A 1991-09-14 1994-03-11 Menetelmä terapeuttisesti käyttökelpoisten 3'-kinuklidinyyli-2-(hydroksimetyyli)-2-fenyylialkanoaattijohdannaisten valmistamiseksi ja välituote FI114707B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9119705 1991-09-14
GB919119705A GB9119705D0 (en) 1991-09-14 1991-09-14 Therapeutic compounds
EP9202067 1992-09-03
PCT/EP1992/002067 WO1993006098A1 (en) 1991-09-14 1992-09-03 Quinuclidine esters process and intermediate for their preparation and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
FI941170A0 true FI941170A0 (fi) 1994-03-11
FI941170A FI941170A (fi) 1994-03-11
FI114707B FI114707B (fi) 2004-12-15

Family

ID=10701448

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941170A FI114707B (fi) 1991-09-14 1994-03-11 Menetelmä terapeuttisesti käyttökelpoisten 3'-kinuklidinyyli-2-(hydroksimetyyli)-2-fenyylialkanoaattijohdannaisten valmistamiseksi ja välituote

Country Status (31)

Country Link
US (1) US5543419A (fi)
EP (1) EP0603229B1 (fi)
JP (2) JP2672030B2 (fi)
KR (1) KR0135784B1 (fi)
CN (1) CN1037269C (fi)
AT (1) ATE167187T1 (fi)
AU (1) AU659487B2 (fi)
BR (1) BR9206499A (fi)
CA (1) CA2116356C (fi)
CZ (1) CZ281752B6 (fi)
DE (1) DE69225897T2 (fi)
DK (1) DK0603229T3 (fi)
EG (1) EG20072A (fi)
ES (1) ES2116343T3 (fi)
FI (1) FI114707B (fi)
GB (1) GB9119705D0 (fi)
GR (1) GR3027667T3 (fi)
HU (1) HU220594B1 (fi)
IL (1) IL103078A (fi)
MX (1) MX9205221A (fi)
MY (1) MY108602A (fi)
NO (1) NO305397B1 (fi)
NZ (1) NZ244324A (fi)
PL (1) PL170627B1 (fi)
PT (1) PT100863B (fi)
RU (1) RU2117669C1 (fi)
SG (1) SG50414A1 (fi)
TW (1) TW251285B (fi)
UA (1) UA42686C2 (fi)
WO (1) WO1993006098A1 (fi)
ZA (1) ZA926939B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE194342T1 (de) * 1996-01-19 2000-07-15 Lonza Ag Verfahren zur herstellung von optisch aktivem 3- chinuclidinol
CZ54498A3 (cs) * 1997-03-07 1998-11-11 Lonza Ag Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití
ATE318595T1 (de) * 1997-08-08 2006-03-15 Univ Duke Zusammensetzungen zur vereinfachung von chirurgischen verfahren
US6711436B1 (en) 1997-08-08 2004-03-23 Duke University Compositions, apparatus and methods for facilitating surgical procedures
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
RU2296762C2 (ru) 2000-12-22 2007-04-10 Альмиралль Продесфарма Аг Карбаматы хинуклидина, способы их получения и фармацевтическая композиция на их основе
BR0116624A (pt) 2000-12-28 2003-12-23 Almirall Prodesfarma Ag Composto, processo para produzir o mesmo, composição farmacêutica, uso do composto ou da composição farmacêutica, e, produto de combinação
DE102004057995A1 (de) * 2004-12-01 2006-06-08 Wacker Chemie Ag Verfahren zur Herstellung von α,α-Dialkyl-α-Hydroxymethyl-Carbonsäurederivaten
JP2010513277A (ja) * 2006-12-13 2010-04-30 ギリード・サイエンシズ・インコーポレーテッド COPDおよび慢性気管支炎の治療のためのムスカリン受容体アンタゴニストおよびβ−アゴニストの共通プロドラッグとしてのモノホスフェート
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
GB8923590D0 (en) * 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators

Also Published As

Publication number Publication date
ES2116343T3 (es) 1998-07-16
IL103078A0 (en) 1993-02-21
MY108602A (en) 1996-10-31
NO940905L (no) 1994-03-14
ATE167187T1 (de) 1998-06-15
PL170627B1 (en) 1997-01-31
DE69225897D1 (de) 1998-07-16
HUT66772A (en) 1994-12-28
IL103078A (en) 1996-07-23
EP0603229A1 (en) 1994-06-29
FI114707B (fi) 2004-12-15
SG50414A1 (en) 1998-07-20
JPH09315970A (ja) 1997-12-09
EG20072A (en) 1999-06-30
CN1070911A (zh) 1993-04-14
KR0135784B1 (ko) 1998-04-23
RU2117669C1 (ru) 1998-08-20
PT100863B (pt) 1999-07-30
JPH06510991A (ja) 1994-12-08
CA2116356A1 (en) 1993-04-01
JP2955533B2 (ja) 1999-10-04
WO1993006098A1 (en) 1993-04-01
ZA926939B (en) 1994-03-11
NO940905D0 (no) 1994-03-14
DE69225897T2 (de) 1998-10-15
HU9400729D0 (en) 1994-06-28
US5543419A (en) 1996-08-06
CA2116356C (en) 1998-03-31
JP2672030B2 (ja) 1997-11-05
FI941170A (fi) 1994-03-11
CZ395392A3 (en) 1994-07-13
AU2482392A (en) 1993-04-27
NZ244324A (en) 1993-12-23
CN1037269C (zh) 1998-02-04
TW251285B (fi) 1995-07-11
UA42686C2 (uk) 2001-11-15
BR9206499A (pt) 1995-11-21
EP0603229B1 (en) 1998-06-10
HU220594B1 (hu) 2002-03-28
DK0603229T3 (da) 1998-10-12
PT100863A (pt) 1993-10-29
MX9205221A (es) 1993-03-01
GR3027667T3 (en) 1998-11-30
AU659487B2 (en) 1995-05-18
GB9119705D0 (en) 1991-10-30
NO305397B1 (no) 1999-05-25
CZ281752B6 (cs) 1997-01-15

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Legal Events

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MA Patent expired