ZA924271B - Tri-and tetravalent mono specific antigen binding proteins - Google Patents
Tri-and tetravalent mono specific antigen binding proteinsInfo
- Publication number
- ZA924271B ZA924271B ZA924271A ZA924271A ZA924271B ZA 924271 B ZA924271 B ZA 924271B ZA 924271 A ZA924271 A ZA 924271A ZA 924271 A ZA924271 A ZA 924271A ZA 924271 B ZA924271 B ZA 924271B
- Authority
- ZA
- South Africa
- Prior art keywords
- tri
- tetravalent
- antigen binding
- binding proteins
- specific antigen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
- C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919112536A GB9112536D0 (en) | 1991-06-11 | 1991-06-11 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA924271B true ZA924271B (en) | 1993-12-13 |
Family
ID=10696461
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA924271A ZA924271B (en) | 1991-06-11 | 1992-06-11 | Tri-and tetravalent mono specific antigen binding proteins |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0560947B1 (fr) |
JP (1) | JP3373849B2 (fr) |
KR (1) | KR930701490A (fr) |
AT (1) | ATE192457T1 (fr) |
AU (1) | AU1971692A (fr) |
CA (1) | CA2088367C (fr) |
DE (1) | DE69230994T2 (fr) |
DK (1) | DK0560947T3 (fr) |
ES (1) | ES2146212T3 (fr) |
FI (1) | FI930580A (fr) |
GB (1) | GB9112536D0 (fr) |
NO (1) | NO930440L (fr) |
NZ (1) | NZ243099A (fr) |
WO (1) | WO1992022583A2 (fr) |
ZA (1) | ZA924271B (fr) |
Families Citing this family (153)
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AU675268B2 (en) * | 1992-12-10 | 1997-01-30 | Celltech Limited | Humanised antibodies directed against A33 antigen |
DE4310141A1 (de) * | 1993-03-29 | 1994-10-06 | Boehringer Mannheim Gmbh | Homobidentale trifunktionelle Linker |
DE4310142A1 (de) * | 1993-03-29 | 1994-10-06 | Boehringer Mannheim Gmbh | Immunologisch aktive Konjugate und ein Verfahren zu ihrer Herstellung |
GB9812545D0 (en) | 1998-06-10 | 1998-08-05 | Celltech Therapeutics Ltd | Biological products |
GB9824632D0 (en) | 1998-11-10 | 1999-01-06 | Celltech Therapeutics Ltd | Biological compounds |
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US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
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GB0013810D0 (en) | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
GB0124317D0 (en) | 2001-10-10 | 2001-11-28 | Celltech R&D Ltd | Biological products |
EP1534753B1 (fr) | 2002-05-28 | 2011-08-03 | UCB Pharma, S.A. | Isomeres de position de peg d'un anticorps contre le tnfalpha (cdp870) |
WO2004042017A2 (fr) | 2002-10-31 | 2004-05-21 | Genentech, Inc. | Methodes et compositions pouvant augmenter la production d'anticorps |
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ES2382879T3 (es) | 2005-09-14 | 2012-06-14 | Ucb Pharma, S.A. | Conjugado de anticuerpo - polímero de peine. |
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EP1897886A1 (fr) * | 2006-09-08 | 2008-03-12 | Bayer Schering Pharma Aktiengesellschaft | Composés utilisés en tant que dimères d'aptamères et leurs utilisations dans le diagnostic et la thérapie |
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DK172629B1 (da) * | 1986-02-14 | 1999-03-22 | Nihon Mediphysics Co Ltd | Reaktive højmolekylære forbindelser med mindst én fri aminogruppe, højmolekylære forbindelser kombineret med et fysiologisk |
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GB8719042D0 (en) * | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
GB8719041D0 (en) * | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
GB8903022D0 (en) * | 1989-02-10 | 1989-03-30 | Celltech Ltd | Chemical compounds |
AU6290090A (en) * | 1989-08-29 | 1991-04-08 | University Of Southampton | Bi-or trispecific (fab)3 or (fab)4 conjugates |
EP0462246A4 (en) * | 1989-11-07 | 1992-11-25 | Bristol-Myers Squibb Company | Oligomeric immunoglobulins |
US5091542A (en) * | 1990-03-09 | 1992-02-25 | Hybritech Incorporated | Tris-maleimido compounds as intermediates in trifunctional antibody synthesis |
GB9012995D0 (en) * | 1990-06-11 | 1990-08-01 | Celltech Ltd | Multivalent antigen-binding proteins |
-
1991
- 1991-06-11 GB GB919112536A patent/GB9112536D0/en active Pending
-
1992
- 1992-06-11 CA CA002088367A patent/CA2088367C/fr not_active Expired - Lifetime
- 1992-06-11 ZA ZA924271A patent/ZA924271B/xx unknown
- 1992-06-11 JP JP51108392A patent/JP3373849B2/ja not_active Expired - Fee Related
- 1992-06-11 KR KR1019930700387A patent/KR930701490A/ko not_active Application Discontinuation
- 1992-06-11 NZ NZ243099A patent/NZ243099A/en not_active IP Right Cessation
- 1992-06-11 EP EP92912329A patent/EP0560947B1/fr not_active Expired - Lifetime
- 1992-06-11 WO PCT/GB1992/001047 patent/WO1992022583A2/fr active IP Right Grant
- 1992-06-11 ES ES92912329T patent/ES2146212T3/es not_active Expired - Lifetime
- 1992-06-11 DE DE69230994T patent/DE69230994T2/de not_active Expired - Lifetime
- 1992-06-11 AT AT92912329T patent/ATE192457T1/de not_active IP Right Cessation
- 1992-06-11 AU AU19716/92A patent/AU1971692A/en not_active Abandoned
- 1992-06-11 DK DK92912329T patent/DK0560947T3/da active
-
1993
- 1993-02-09 NO NO93930440A patent/NO930440L/no unknown
- 1993-02-10 FI FI930580A patent/FI930580A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU1971692A (en) | 1993-01-12 |
ATE192457T1 (de) | 2000-05-15 |
KR930701490A (ko) | 1993-06-11 |
DE69230994T2 (de) | 2001-02-01 |
WO1992022583A2 (fr) | 1992-12-23 |
NO930440D0 (no) | 1993-02-09 |
CA2088367C (fr) | 2002-08-20 |
CA2088367A1 (fr) | 1992-12-12 |
WO1992022583A3 (fr) | 1993-04-01 |
FI930580A (fi) | 1993-04-02 |
DK0560947T3 (da) | 2000-08-07 |
EP0560947A1 (fr) | 1993-09-22 |
NO930440L (no) | 1993-04-02 |
DE69230994D1 (de) | 2000-06-08 |
JPH06502657A (ja) | 1994-03-24 |
EP0560947B1 (fr) | 2000-05-03 |
JP3373849B2 (ja) | 2003-02-04 |
FI930580A0 (fi) | 1993-02-10 |
ES2146212T3 (es) | 2000-08-01 |
NZ243099A (en) | 1996-07-26 |
GB9112536D0 (en) | 1991-07-31 |
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