ZA90430B - Bis-aza-bicyclic anxiolytic agents - Google Patents

Bis-aza-bicyclic anxiolytic agents

Info

Publication number
ZA90430B
ZA90430B ZA90430A ZA90430A ZA90430B ZA 90430 B ZA90430 B ZA 90430B ZA 90430 A ZA90430 A ZA 90430A ZA 90430 A ZA90430 A ZA 90430A ZA 90430 B ZA90430 B ZA 90430B
Authority
ZA
South Africa
Prior art keywords
aza
bis
anxiolytic agents
bicyclic
bicyclic anxiolytic
Prior art date
Application number
ZA90430A
Other languages
English (en)
Inventor
Kishor Amratral Desai
Amratral Desai Kishor
Gene Michael Bright
Michael Bright Gene
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to ZA906885A priority Critical patent/ZA906885B/xx
Publication of ZA90430B publication Critical patent/ZA90430B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
ZA90430A 1989-01-23 1990-01-22 Bis-aza-bicyclic anxiolytic agents ZA90430B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ZA906885A ZA906885B (en) 1990-01-22 1990-08-29 Drying and/or heating device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/000275 WO1990008148A1 (en) 1989-01-23 1989-01-23 Bis-aza-bicyclic anxiolytic agents

Publications (1)

Publication Number Publication Date
ZA90430B true ZA90430B (en) 1991-08-28

Family

ID=22214801

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90430A ZA90430B (en) 1989-01-23 1990-01-22 Bis-aza-bicyclic anxiolytic agents

Country Status (38)

Country Link
US (1) US5122525A (ko)
EP (1) EP0380217B1 (ko)
JP (1) JPH0643427B2 (ko)
KR (1) KR910009289B1 (ko)
CN (1) CN1022186C (ko)
AP (1) AP128A (ko)
AR (1) AR246969A1 (ko)
AT (1) ATE82574T1 (ko)
AU (1) AU614214B2 (ko)
BA (1) BA98302A (ko)
BG (1) BG51046A3 (ko)
CA (1) CA2008108C (ko)
CZ (1) CZ277698B6 (ko)
DD (1) DD291560A5 (ko)
DE (1) DE69000467T2 (ko)
DK (1) DK0380217T3 (ko)
EG (1) EG19306A (ko)
ES (1) ES2053094T3 (ko)
FI (1) FI95381C (ko)
GR (1) GR3006925T3 (ko)
HU (1) HU215154B (ko)
IE (1) IE62670B1 (ko)
IL (1) IL93073A (ko)
IS (1) IS1667B (ko)
MA (1) MA21735A1 (ko)
MX (1) MX19222A (ko)
MY (1) MY104861A (ko)
NO (1) NO175978C (ko)
NZ (1) NZ232168A (ko)
OA (1) OA10041A (ko)
PL (1) PL163836B1 (ko)
PT (1) PT92919B (ko)
RO (1) RO110142B1 (ko)
RU (1) RU2015977C1 (ko)
SK (1) SK279339B6 (ko)
WO (2) WO1990008148A1 (ko)
YU (1) YU47554B (ko)
ZA (1) ZA90430B (ko)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990008148A1 (en) * 1989-01-23 1990-07-26 Pfizer Inc. Bis-aza-bicyclic anxiolytic agents
WO1992000075A1 (en) * 1990-06-29 1992-01-09 Pfizer Inc. Pyridopyrazine derivatives for treating substance abuse and addiction
ES2072141T3 (es) * 1991-01-31 1995-07-01 Pfizer Resolucion de trans-2-(2-pirimidinil)-7-(hidroximetil)octahidro-2h-pirido(1,2a)pirazina.
DE69218414T2 (de) * 1991-02-27 1998-01-22 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten
US5157034A (en) * 1991-02-27 1992-10-20 Pfizer Inc. Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
US5185449A (en) * 1991-02-27 1993-02-09 Pfizer Inc. Process and intermediate for certain bis-aza-bicyclic anxiolytic agents
US5311195A (en) * 1991-08-30 1994-05-10 Etak, Inc. Combined relative and absolute positioning method and apparatus
HUT71488A (en) * 1991-09-25 1995-11-28 Pfizer Process for the production of neuroleptic 2-substituted perhydro-1-h-pyrido[1,2a]pyrazines and pharmaceuticals compositions containing the same
US5719286A (en) * 1992-06-16 1998-02-17 Pfizer Inc. Process and intermediates for bis-aza-bicyclic anxiolytic agents
WO1994006794A1 (en) * 1992-09-24 1994-03-31 National Institutes Of Health Aralkyl diazabicycloalkane derivatives for cns disorders
IL104506A (en) * 1993-01-25 1997-11-20 Israel State Fast changing heating- cooling device and method, particularly for cryogenic and/or surgical use
US5637713A (en) * 1993-08-20 1997-06-10 Pfizer Inc. Process for preparing trans-piperidine-2,5-dicarboxylates
US5455350A (en) * 1993-10-13 1995-10-03 Pfizer Inc. Process and intermediate for certain bis-aza-bicyclic anxiolytic agents
IL107460A (en) * 1993-11-01 1999-06-20 Israel State Controlled cryogenic contact system
ES2166830T3 (es) * 1994-09-30 2002-05-01 Pfizer Derivados 2,7-sustituidos de octahidro-1h-pirido(1,2-a)pirazina.
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
WO1996010570A1 (en) * 1994-09-30 1996-04-11 Pfizer Inc. NEUROLEPTIC 2,7-DISUBSTITUTED PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES
RU2162470C2 (ru) * 1995-12-21 2001-01-27 Пфайзер Инк. 2,7-замещенные производные октагидропирроло[1,2-а]пиразина, способ лечения, фармацевтическая композиция, промежуточные соединения
BR9710018A (pt) * 1996-07-01 1999-08-10 Pfizer Preparação de (7S,trans)-2-(2-pirimidinil)-7-(hidroximetil)octa-hidro-2H-pirido[1,2-A]pirazina
PA8469101A1 (es) * 1998-04-09 2000-09-29 Pfizer Prod Inc Ligandos azabiciclicos de receptores 5ht1
US6251893B1 (en) * 1998-06-15 2001-06-26 Nps Allelix Corp. Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
HN1999000146A (es) * 1998-09-21 2000-11-11 Pfizer Prod Inc Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas.
US20020016334A1 (en) * 2000-07-31 2002-02-07 Coe Jotham Wadsworth Pharmaceutical composition for the treatment of attention deficit hyperactivity disorder (ADHD)
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine
EA009527B1 (ru) * 2003-03-12 2008-02-28 Пфайзер Продактс Инк. Пиридилоксиметильные и бензизоксазольные азабициклические производные
WO2004092173A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. A2a adenosine receptor antagonists
DK1689721T3 (da) * 2003-11-26 2010-09-20 Pfizer Prod Inc Aminopyrazolderivater som GSK-3-ihibitorer
BRPI0511529A (pt) * 2004-05-27 2008-01-02 Warner Lambert Co combinação terapêutica para distúrbios de hiperatividade/déficit de atenção
US7658206B2 (en) 2006-12-05 2010-02-09 Kohler Co. Plumbing valve with stick control handle

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
US4339579A (en) * 1980-12-29 1982-07-13 American Home Products Corporation 2,6-Bis-(pyrrolopyrazinyl)pyrazines
US4400511A (en) * 1982-05-07 1983-08-23 American Home Products Corporation 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids
US4414389A (en) * 1982-05-25 1983-11-08 American Home Products Corporation 4-Substituted-piperidino carboxamides
US4517187A (en) * 1982-10-18 1985-05-14 Pennwalt Corporation 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3409440A1 (de) * 1984-03-15 1985-09-26 Bayer Ag, 5090 Leverkusen Imidazo(1,5-a)pyridyl-methan- und imidazo(1,5-b)pyridazinylmethan-derivate, ihre herstellung und sie enthaltende aufzeichnungsmaterialien
IT1204803B (it) * 1986-02-17 1989-03-10 Acraf Composto farmacologicamente attivo e composizioni farmaceutiche che lo contengono,procedimento per prepararlo e intermedio utile in detto procedimento
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
JP2668259B2 (ja) * 1988-02-18 1997-10-27 塩野義製薬株式会社 複素環化合物および抗潰瘍剤
WO1990008148A1 (en) * 1989-01-23 1990-07-26 Pfizer Inc. Bis-aza-bicyclic anxiolytic agents

Also Published As

Publication number Publication date
SK279339B6 (sk) 1998-10-07
KR900011774A (ko) 1990-08-02
NO175978C (no) 1995-01-11
EG19306A (en) 1995-01-31
US5122525A (en) 1992-06-16
FI95381C (fi) 1996-01-25
PT92919B (pt) 1995-12-29
DE69000467D1 (de) 1992-12-24
CS29990A3 (en) 1992-11-18
AP9000158A0 (en) 1990-01-31
RO110142B1 (ro) 1995-10-30
MA21735A1 (fr) 1990-10-01
IL93073A (en) 1994-05-30
CA2008108C (en) 1995-08-08
FI913510A0 (fi) 1991-07-22
HU215154B (hu) 2000-09-28
IS3529A7 (is) 1990-07-24
PT92919A (pt) 1990-07-31
MY104861A (en) 1994-06-30
AR246969A1 (es) 1994-10-31
AU614214B2 (en) 1991-08-22
YU47554B (sh) 1995-10-03
NO912863L (no) 1991-07-22
DD291560A5 (de) 1991-07-04
RU2015977C1 (ru) 1994-07-15
MX19222A (es) 1993-12-01
PL163836B1 (pl) 1994-05-31
AU4867990A (en) 1990-07-26
KR910009289B1 (ko) 1991-11-09
OA10041A (en) 1996-10-14
HUT63163A (en) 1993-07-28
CA2008108A1 (en) 1990-07-23
CN1022186C (zh) 1993-09-22
GR3006925T3 (ko) 1993-06-30
YU11190A (sh) 1993-05-28
CZ277698B6 (en) 1993-03-17
IE62670B1 (en) 1995-03-08
JPH02233681A (ja) 1990-09-17
ATE82574T1 (de) 1992-12-15
BG51046A3 (en) 1993-01-15
JPH0643427B2 (ja) 1994-06-08
IE900225L (en) 1990-07-23
AP128A (en) 1991-03-20
CN1044464A (zh) 1990-08-08
WO1990008148A1 (en) 1990-07-26
DK0380217T3 (da) 1992-12-14
IS1667B (is) 1997-11-14
EP0380217A1 (en) 1990-08-01
EP0380217B1 (en) 1992-11-19
NO175978B (no) 1994-10-03
ES2053094T3 (es) 1994-07-16
DE69000467T2 (de) 1993-04-01
NZ232168A (en) 1991-08-27
FI95381B (fi) 1995-10-13
NO912863D0 (no) 1991-07-22
BA98302A (bs) 2001-09-14
WO1990008144A1 (en) 1990-07-26

Similar Documents

Publication Publication Date Title
ZA90430B (en) Bis-aza-bicyclic anxiolytic agents
DE69030767D1 (en) Defibrillationselektrode
GB2235563B (en) Guitar-style synthesizer-controllers
AU108277S (en) Hedge-shears
EP0405242A3 (en) Vip-analogs ii
IL94829A0 (en) Indenoindoles i
GB8912309D0 (en) Phonecorder
CS490790A3 (en) Chaff-cutter
IL94778A0 (en) Thioxotetrazolines
GB8906867D0 (en) Becvem
GB8911764D0 (en) Cornerwise
EP0424336A3 (en) Subwarhead
GB9003724D0 (en) Toychest ii
BG49771A1 (en) Electric- bow evaparator
GB8900732D0 (en) Agents
EP0430866A3 (en) Connection piece
EP0417059A3 (en) Bicyclic tetrahydroxylated pyrrolizidines
GB8915677D0 (en) Cancrusher
GB8901318D0 (en) Animotion
GB8917621D0 (en) Possette
GB8923417D0 (en) Rod-strip
EP0435208A3 (en) Neuro-computer
CA64817S (en) Liminaire
CA64463S (en) Tapeplayer
CA64838S (en) Automibile