ZA882827B - Ibuprofen sustained release matrix and process - Google Patents

Ibuprofen sustained release matrix and process

Info

Publication number
ZA882827B
ZA882827B ZA882827A ZA882827A ZA882827B ZA 882827 B ZA882827 B ZA 882827B ZA 882827 A ZA882827 A ZA 882827A ZA 882827 A ZA882827 A ZA 882827A ZA 882827 B ZA882827 B ZA 882827B
Authority
ZA
South Africa
Prior art keywords
ibuprofen
sustained release
granulation
release matrix
erosion
Prior art date
Application number
ZA882827A
Other languages
English (en)
Inventor
Galen Wesley Radebaugh
Wesley Radebaugh Galen
Thomas Nicholas Julian
Nicholas Julian Thomas
Robert Glinecke
Glinecke Robert
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of ZA882827B publication Critical patent/ZA882827B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA882827A 1987-04-22 1988-04-21 Ibuprofen sustained release matrix and process ZA882827B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/041,164 US4806359A (en) 1987-04-22 1987-04-22 Iburprofen sustained release matrix and process

Publications (1)

Publication Number Publication Date
ZA882827B true ZA882827B (en) 1989-12-27

Family

ID=21915089

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA882827A ZA882827B (en) 1987-04-22 1988-04-21 Ibuprofen sustained release matrix and process

Country Status (21)

Country Link
US (1) US4806359A (de)
EP (2) EP0290168B1 (de)
JP (2) JP2519296B2 (de)
KR (1) KR960007750B1 (de)
AT (1) ATE86479T1 (de)
AU (2) AU604110B2 (de)
CA (1) CA1310272C (de)
DE (2) DE3865077D1 (de)
ES (1) ES2039277T3 (de)
GR (1) GR1000019B (de)
HK (1) HK22892A (de)
IE (1) IE62786B1 (de)
IN (1) IN165929B (de)
MY (1) MY103076A (de)
NO (1) NO176203C (de)
NZ (1) NZ224278A (de)
PH (1) PH25176A (de)
PT (1) PT87285B (de)
SG (1) SG104091G (de)
WO (1) WO1988008299A1 (de)
ZA (1) ZA882827B (de)

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US5104648A (en) * 1989-02-02 1992-04-14 Mallinckrodt Specialty Chemicals Company High ibuprofen content granulations
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
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FR2677886B1 (fr) * 1991-06-18 1995-03-31 Adir Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale.
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140179C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Ibuprofen enthaltendes Arzneimittel
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DE4140172C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Ibuprofen enthaltendes Arzneimittel
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HU230440B1 (hu) * 1999-03-31 2016-06-28 Janssen Pharmaceutica N.V Előgélesített keményítőt tartalmazó szabályozott felszabadulású készítmények
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JP2004522752A (ja) * 2001-02-05 2004-07-29 アール．ピー． シェーラー テクノロジーズ インコーポレイテッド 薬学的活性剤の味を軽減するための方法および組成物
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
PL223471B1 (pl) * 2002-03-15 2016-10-31 Cypress Bioscience Inc Kompozycja farmaceutyczna zawierająca milnacypran do stosowania w leczeniu zespołu nadwrażliwości jelita grubego
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
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EP1663145B1 (de) * 2003-09-26 2011-04-06 ALZA Corporation Oros-push-stick für die kontrollierte abgabe von wirkstoffen
JP4919801B2 (ja) * 2003-09-26 2012-04-18 アルザ・コーポレーシヨン 高い薬剤配合量を提供する薬剤コーティング及びそれを提供する方法
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US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
ES2403069T3 (es) * 2005-02-22 2013-05-13 Sun Pharma Advanced Research Company Ltd Composición oral de liberación controlada que contiene levetiracetam
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US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
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Also Published As

Publication number Publication date
AU604110B2 (en) 1990-12-06
IE62786B1 (en) 1995-02-22
PT87285A (pt) 1988-05-01
WO1988008299A1 (en) 1988-11-03
DE3879080T2 (de) 1993-07-15
PT87285B (pt) 1992-08-31
ES2039277T3 (es) 1993-09-16
AU1719788A (en) 1988-12-02
NZ224278A (en) 1990-09-26
JP2776856B2 (ja) 1998-07-16
MY103076A (en) 1993-04-30
EP0290168B1 (de) 1991-09-25
JPH01503070A (ja) 1989-10-19
IE881195L (en) 1988-10-22
HK22892A (en) 1992-04-03
US4806359A (en) 1989-02-21
SG104091G (en) 1992-02-14
NO881732D0 (no) 1988-04-21
NO881732L (no) 1988-10-24
DE3865077D1 (de) 1991-10-31
KR960007750B1 (ko) 1996-06-12
GR880100258A (en) 1989-01-31
ATE86479T1 (de) 1993-03-15
KR880012213A (ko) 1988-11-26
DE3879080D1 (de) 1993-04-15
NO176203B (no) 1994-11-14
PH25176A (en) 1991-03-27
CA1310272C (en) 1992-11-17
EP0312581B1 (de) 1993-03-10
JP2519296B2 (ja) 1996-07-31
EP0312581A1 (de) 1989-04-26
NO176203C (no) 1995-02-22
GR1000019B (el) 1990-01-31
EP0290168A1 (de) 1988-11-09
AU1477488A (en) 1988-10-27
IN165929B (de) 1990-02-10
JPS63280021A (ja) 1988-11-17
AU603675B2 (en) 1990-11-22

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